Objective(s): To determine the sexual dysfunction rate and related factors in women of reproductive age who had been infected with SARS-CoV-2 in Phu Nhuan District, Ho Chi Minh City, Vietnam.Methods: A cross-sectional study was conducted between 01/11/2022 and 30/03/2023 over 387 women aged 18 -49 years who had been infected with SARS-CoV-2 at least one time, and were living in Phu Nhuan District, HCM City.Data collection was made by online interview with Google form based on FSFI questionnaire.Results: Overall sexual dysfunction rate in the women of study is 57.6%; the rates of specific sexual domains include reduced libido (92.2%); reduced arousal (82.7%); insufficient lubrication (69.3%); anorgasmia (73.6%); lack of satisfaction (81.9%), and dyspareunia (63.6%).Women with sexual dysfunction were referred to the Sexual Counseling Unit of Tu Du Hospital for appropriate intervention.Poisson multivariate regression analysis shows that "age group 41-49" has a 1.37 times higher risk of overall sexual dysfunction than age group 18-30 (PR*: 1.37; 95%CI 1.06 -1.76), and women with sexual dysfunction have "a shorter interval between SARS-CoV-2 infection and the survey point of time" than those without sexual dysfunction (p= 0.005).Conclusion: Overall, sexual dysfunction and specific sexual disorder rates remarkably increased in Phu Nhuan women of reproductive age who were infected with SARS-CoV-2.Therefore, there should be a post-Covid strategy to screen for early detection and prompt intervention to help influenced subjects.

Background: Carcinomas of the oral cavity can be debilitating, making postsurgical rehabilitation crucial for maintaining the patient's quality of life.Adenoid cystic carcinomas (ACC) represent 3% to 5% of all malignant neoplasms in the head and neck region.Case presentation: This report presents a case of adenoid cystic carcinoma of the hard palate.The patient reported swelling in the hard palate, as well as externally on the right nasolabial fold and infra-orbital region.A preliminary diagnosis of a minor salivary gland tumor was made.No distant organ metastasis had occurred.Incisional biopsy reported the swelling as adenoid cystic carcinoma of a solid pattern.A subtotal maxillectomy with radial free flap reconstruction was planned.Due to the failure of the flap reconstruction, a surgical obturator became necessary.Conclusion: The surgical obturator enhanced the patient's quality of life after surgery by incorporating teeth, a feature not found in conventional obturators.This allowed the patient to consume a soft diet more easily.

Background: Asian countries exhibit a high prevalence of hypertension., substantially increasing the burden of cardiovascular diseases owing to variables such as lifestyle choices, eating habits, and genetic dispositions. Objective: The systematic review evaluates the effectiveness of collaborative care approaches in the treatment of hypertension and the corresponding complications, emphasizing the significance of interdisciplinary healthcare teams in enhancing patient outcomes. Methodology: The researchers conducted a systematic evaluation using several search engines to find intervention-based experimental studies. A comprehensive search was carried out using one or more of the following online databases: Web of Science, Google Scholar, Science Direct, Pro Quest, Pub Med, Research Gate, and Scopus. The research group conducted this systematic review following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)" guidelines. Results: This review incorporated the latest research findings ranging from 2003 to 2023. The present review included a total of 20 studies that met the specified criteria out of 2334 studies. Interventions that involve collaboration among healthcare professionals, such as pharmacists, nurses, and dietitians in Asia, resulted in significant decreases in both systolic and diastolic blood pressure among individuals. We used the ZEE tool to evaluate the quality and relevancy of the research. Conclusion: The review demonstrates the effectiveness of the collaborative care framework and emphasizes the need for a multidisciplinary approach in educating patients.

Vermiform appendix torsion is a rare acute abdominal emergency in the pediatric population, with possibly 25 case reports appearing in English-language publications since 1918, when it was initially described, surgeons mostly accidentally found it during surgery.It can be primary or secondary.Clinical manifestations mimic acute appendicitis.This vermiform appendix torsion is a case report of a 9-year-old girl who had her appendix twisted on itself 360 degrees in an anticlockwise direction.A late diagnosis can result in the appendix being gangrenous.We report a case of a 9-year-old girl who presented to the emergency department with abdominal pain, non-bilious vomiting, constipation, and fever.Laboratory data revealed a white cell count of 19,000 per microliter, with 74% neutrophils.Abdominal Ultrasound was inconclusive.Surgeons performed an emergency laparoscopic exploration with a provisional diagnosis of acute appendicitis.A laparoscopic examination revealed an anticlockwise 360° twist in the appendix.They performed an appendectomy, and the recovery after the procedure went smoothly.Vermiform appendix torsion is a highly uncommon ailment that might be challenging to differentiate from acute appendicitis.Late detection and inappropriate management plans can result in the appendix gangrene and perforation.In pediatric patients with acute abdominal pain, it is critical to consider appendicular torsion as a differential diagnosis.

Background: The success of intrauterine insemination (IUI) can be influenced by multiple factors, extending beyond age and the number of treatment cycles.Objectives: This study aims to conduct a thorough analysis of 466 IUI treatment cycles performed on 221 patients at a fertility center within a university hospital between 2021 and 2023.Methods: A retrospective review of medical records was conducted, encompassing 466 IUI treatment cycles performed on 221 patients at a university hospital's fertility center from 2021 to 2023.Female patients were categorized into three age groups: below 35 years old, between 35 and 40 years old, and over 40 years old.The study evaluated multiple outcomes, including rates of biochemical pregnancy, clinical pregnancy, live births, and miscarriages.A Kaplan-Meier analysis was employed to assess treatment cycle success within each age group.Results: The average age of the patients was 35.2 years, ranging from 21 to 49 years.The overall rate of biochemical pregnancy was 69.6%.Biochemical pregnancy rates significantly declined with increasing female age, with rates of 45.6% for those below 35 years old, 39.8% for those aged 35 to 40 years, and 34.1% for those over 40 years old (p = 0.002).However, there were no significant differences observed in other pregnancy outcomes across different age groups.The cumulative biochemical pregnancy rate increased up to four cycles in all age groups.Conclusion: It is recommended to consider up to four insemination cycles before proceeding to an IVF/ICSI cycle.

Objective: Formulation aims to develop a film that dissolves quickly for advanced solid dosage forms in order to increase the drug's bioavailability and enhance its action. Natural gum and artificial polymers were combined to develop films with the desired properties. Method: Metoclopramide FDF was developed in nine different formulations (F1-F9) using the solvent casting process. The effect of varying formulation parameters on the physical and mechanical characteristics of metoclopramide films was investigated in vitro using phosphate buffer at 6.8 pH. Several techniques were used to evaluate the films' weight, thickness, tensile strength, folding durability, and oral dissolving time in order to determine the best possible formulation. Results: The findings showed that the materials were employed consistently throughout the whole film in terms of drug content. While all the formulations had acceptable testing features, formulation F7 was deemed the most promising due to its 99.12% in-vitro drug release and other characteristics. All the formulations are shown to obey first-order kinetics and fickian release. The formulation showed enhanced drug release rates over a 9minute period, indicating its adaptability. It contained the ideal polymer concentrations of Cyamopsis tetragonoloba gum, HPMC, and PEG. Conclusion: The study suggests that metoclopramide fast-dissolving oral films are the most effective antiemetic option for quick onset of action and enhanced bioavailability.

Background: Mini-gastric bypass (MGB) surgery is a successful and secure method for losing weight. It provides lasting weight loss with the possibility of revision or reversal. The procedure has potential benefits such as reduced surgery duration and enhanced patient contentment. Nevertheless, there are ongoing worries about its anatomical structure and metabolic consequences. Objectives: This systematic review aims to evaluate the safety and efficacy of MGB surgery. It assesses postoperative complications, adverse events, weight loss outcomes, and resolution of comorbidities. The review provides guidance for clinicians, researchers, and patients in their decision-making process. Methods: The study design followed the guidelines for meta-analyses of interventional studies. The researchers conducted a thorough investigation by exploring five scholarly databases, including PubMed, Scopus, Google scholar, and Web of Science. Their objective was to identify any published materials from the period of 2014 to 2024 available in each database. To accomplish this, they devised an all-encompassing search strategy utilizing MeSH keywords. Within the realm of their study, they utilized the phrases "Safety and Efficacy", "Mini-Gastric Bypass Surgery", "Clinical trials", and "observational" to further enrich their investigation. Results: 156 articles were collected, nine full-text studies included in the review. The included studies provide insights into the safety and efficacy of MGB surgery. Studies from different countries report positive outcomes related to resolution of comorbidities and weight loss. Conclusion: MGB surgery is a promising alternative for those considering bariatric surgery. More research and follow-up studies are necessary for concerns and standard of care establishment.

Background: Burnout among healthcare professionals, particularly nurses, is a significant concern globally.Emergency department (ED) nurses, operating in high-stress environments, may be particularly vulnerable to burnout.This study aimed to investigate the prevalence of burnout and its association with various sociodemographic factors among ED nurses in Saudi Arabia.Study Aim: To determine the prevalence of burnout and identify sociodemographic factors associated with burnout among ED nurses.Methodology: A cross-sectional study was conducted involving 179 ED nurses in Saudi Arabia, to evaluate burnout, the Maslach Burnout Inventory was utilized.Categorizing scores into high and low burnout.Sociodemographic factors including age, gender, marital status, nationality, current housing status, and years of experience were analyzed for their association with burnout using chi-square tests.When a p-value was less than 0.05, statistical significance was reached.Results: The overall prevalence of burnout among ED nurses was 65.4%.Personal burnout was reported by 60.2% of participants, work-related burnout by 64.4%, and patient-related burnout by 49.8%.Younger nurses (25-29 years) demonstrated significantly higher burnout scores compared to other age groups (χ² = 10.843,p = 0.028).Saudi nationality was associated with higher burnout prevalence (χ² = 10.505,p = 0.033).Significant correlations were found between personal, work-related, and patient-related burnout domains (p < 0.001).Conclusion: The interconnected nature of burnout domains emphasizes the need for comprehensive interventions.These findings provide insights for healthcare organizations to develop targeted strategies to mitigate burnout among ED nurses and enhance overall workforce well-being.

Background: In Saudi Arabia, sickle-cell disease is among the most prevalent hematologic hereditary illnesses. In SCD patients, vascular-occlusive pain crises are a common reason for emergency room visits, and patients' suffering may go untreated. This research offers a systematic literature review of the current treatments for acute pain crises in SCD patients. Method: The authors examined five scientific databases-MEDLINE, PubMed, CENTRAL, CINAHL, and Web of Science-to locate published works through 2023. For every database, a comprehensive search strategy was developed using MeSH keywords. The phrases opioids, anemia, sickle cell, double-blinded, randomized controlled study, acute pain, and clinical trial are used. Results: Six full-text articles with 424 patients were included for our review out of the 201 articles initially gathered from databases. Duplication was removed, and the articles were assessed against inclusion criteria. Of the included studies, three were conducted in the United States, one in Connecticut, one in Maryland, and one in Canada. Using guidelines for higher opioid doses for acute painful episodes in SCD patients was related to better pain outcomes and fewer hospitalizations. According to current standards, patients with SCD should get opioid analgesia within 30 minutes of being triaged. Conclusion: Almost all SCD patients who were hospitalized as a result of acute pain were provided opioids; there's no set method in strict accordance with guidelines from the Centers for Disease Control and Prevention.