Zinc oxide is a safe material for humans, with high biocompatibility and negligible cytotoxicity. Interestingly, it shows exceptional antimicrobial activity against bacteria, viruses, fungi, etc., especially when reduced to the nanometer size. As it is easily understandable, thanks to its properties, it is at the forefront of safe antimicrobials in this pandemic era. Besides, in the view of the 2022 European Green Deal announced by the European Commission, even science and nanotechnology are moving towards “greener” approaches to the synthesis of nanoparticles. Among them, biogenic ZnO nanoparticles have been extensively studied for their biological applications and environmental remediation. Plants, algae, fungi, yeast, etc., (which are composed of naturally occurring biomolecules) play, in biogenic processes, an active role in the formation of nanoparticles with distinct shapes and sizes. The present review targets the biogenic synthesis of ZnO nanoparticles, with a specific focus on their bioactive properties and antimicrobial application.

Among halogenated molecules, those containing chlorine atoms are fundamental in many areas such as pharmaceuticals, polymers, agrochemicals and natural metabolites. Despite the fact that many reactions have been developed to install chlorine on organic molecules, most of them rely on toxic and hazardous chlorinating reagents as well as harsh conditions. In an attempt to move towards more sustainable approaches, photoredox catalysis and electrocatalysis have emerged as powerful alternatives to traditional methods. In this review, we collect the most recent and significant examples of visible-light- or current-mediated chlorination published in the last five years.

The utilization of crude glycerol, generated as a by-product from the biodiesel production process, for the production of high value-added products represents an opportunity to overcome the negative impact of low glycerol prices in the biodiesel industry. In this study, the biochemical behavior of Yarrowia lipolytica strains FMCC Y-74 and FMCC Y-75 was investigated using glycerol as a carbon source. Initially, the effect of pH value (3.0–7.0) was examined to produce polyols, intracellular lipids, and polysaccharides. At low pH values (initial pH 3.0–5.0), significant mannitol production was recorded. The highest mannitol production (19.64 g L−1) was obtained by Y. lipolytica FMCC Y-74 at pH = 3.0. At pH values ranging between 5.0 and 6.0, intracellular polysaccharides synthesis was favored, while polyols production was suppressed. Subsequently, the effect of crude glycerol and its concentration on polyols production was studied. Y. lipolytica FMCC Y-74 showed high tolerance to impurities of crude glycerol. Initial substrate concentrations influence polyols production and distribution with a metabolic shift toward erythritol production being observed when the initial glycerol concentration (Gly0) increased. The highest total polyols production (=56.64 g L−1) was obtained at Gly0 adjusted to ≈120 g L−1. The highest polyols conversion yield (0.59 g g−1) and productivity (4.36 g L−1 d−1) were reached at Gly0 = 80 g L−1. In fed-batch intermittent fermentation with glycerol concentration remaining ≤60 g L−1, the metabolism was shifted toward mannitol biosynthesis, which was the main polyol produced in significant quantities (=36.84 g L−1) with a corresponding conversion yield of 0.51 g g−1.

The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although, with the benefit of increased diagnostic techniques and improved understanding, these structures are attracting greater attention in additional research settings, including applications as organic radicals and semiconductors. In addition, the benzodithiazole functionality has been shown to be a valuable synthetic intermediate in the preparation of a variety of other privileged aromatic and heteroaromatic targets, many of which are important APIs. In this review, the authors aim to critically analyse the potential applicability of these compounds to the fields of not only small-scale laboratory synthetic and medicinal chemistry but also commercial-scale processes and increasingly materials chemistry.

Fischer–Tropsch synthesis (FTS) produces hundreds of hydrocarbons and oxygenates by simple reactants (CO + H2) and the detailed chain propagation mechanism is still in dispute. An industrial iron-based catalyst was used to further clarify the mechanism by adding aldehyde, alcohol and alkene species into a fixed-bed tubular reactor. The added species were investigated in H2 and syngas atmospheres, respectively. 1-alkene in the H2 atmosphere presented an obvious hydrogenolysis, in which the produced C1 species participated in C–C bond formation simultaneously. Co-feeding Cn alkene with syngas showed remarkable Cn+1 alcohol selectivity compared to the normal FTS reaction. In addition, the carbonyl group of aldehyde was extremely unstable over the iron-based catalyst and could easily be hydrogenated to an alcohol hydroxyl group, which could even undergo dehydration for hydrocarbon species formation. Experimental data confirmed that both heavier alkenes and alcohols added can be converted to chain growth intermediates and then undergo monomer insertion for chain propagation. These results provide strong evidence that the chain propagation in the FTS reaction is simultaneously controlled by the surface carbide mechanism and the CO insertion mechanism, with surface CHx species and CO as monomers, respectively. The study is of guiding significance for FTS mechanism understanding and kinetic modeling.

The catalytic production of syngas by the partial oxidation of methane (POM) was investigated over Pd supported on ceria (0.5–2 Pd wt.%) prepared by incipient wetness impregnation and by mechanochemical methods. The performance of the Pd/CeO2 catalyst prepared by milling CeO2 and Pd acetate was superior to that prepared by milling CeO2 and Pd nitrate and to Pd/CeO2 prepared by impregnation from Pd acetate. The best catalytic activity of the Pd/CeO2 catalyst prepared from CeO2 and Pd acetate was obtained by milling at 50 Hz for 5 min. Two-step combustion and reforming reaction mechanism were identified. Remarkably, methane conversion increased progressively with Pd loading for the catalysts prepared by incipient wetness impregnation, whereas low metal loading showed better conversion of methane for the catalysts prepared by ball milling using Pd acetate. This was explained in terms of an impressive dispersion of Pd species with a strong interaction with the surface of ceria, as deduced from transmission electron microscopy, Raman spectroscopy and X-ray photoelectron spectroscopy characterization, which revealed a large quantity of highly oxidized species at the surface.

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The self-condensation and cross-condensation reactions of ethanol and isoamyl alcohol are examined to better understand the potential routes to value-added byproducts from fuel ethanol production. Reactions have been carried out in both batch autoclave and continuous condensed-phase reactors using a lanthanum-promoted, alumina-supported nickel catalyst at near-critical condensed phase conditions. Analysis of multiple candidate kinetic models led to a Langmuir–Hinshelwood rate expression that is first-order in alcohol with water as the strongly adsorbed species. This model provides the best fit of data from both batch and continuous reactor experiments. Activation energies for primary condensation reactions increase as carbon chain lengths increase. Selectivities to higher alcohols of 94% and 87% for ethanol and isoamyl alcohol, respectively, were observed at different operating conditions.

A series of benzylidene-3-pyrrolines were prepared from chalcone derivatives, arylacetylene and sulfonamide via a three-step sequence without the isolation of intermediates. Typically, the reaction of 1,3-di-p-tolylprop-2-en-1-one with lithium phenylacetylide was followed by substitution with tosylamide and then silver-catalyzed 5-exo-dig cyclization to give N-tosyl-2-benzylidene-3,5-di-p-tolyl-2,5-dihydro-1H-pyrrole with a 86% yield. Furthermore, transformation to the corresponding substituted 3-pyrrolin-2-one and pyrrole by m-chloroperbenzoic acid (mcpba)-oxidation and acid-catalyzed aromatization, respectively, was investigated.