In recent years, nanostructures assembled by DNA have found promising applications in optics, medicine, and sensing. DNA origami in particular provides unique self‐assembly properties, not only enabling a vast variety of functionalization schemes but also presenting a promising route to fabricate large‐scale, bottom‐up nanostructured arrays. This approach has comparable precision to electron beam lithography but avoids slow and expensive patterning steps. However, self‐assembly of lattices with high order and well‐defined periodicity requires careful tuning of the deposition parameters and interactions involved, which has been done mostly on mica so far. As mica is not compatible with standard microfabrication processes, we investigate here the assembly of DNA origami lattices on the most general microfabrication material, that is, silicon wafers, which has turned out to be rather challenging. We study how the forming of polycrystalline 2D‐fishnet‐type lattices is influenced by different incubation conditions and strengths of the origami–origami and origami‐surface interactions, with the aim to create large‐scale single‐crystalline lattices. The lattices are characterized by atomic force microscopy and analyzed for precision of formation, achievable domain size, and surface coverage of well‐formed lattices. Thanks to the silicon substrate, these DNA origami lattices can be further combined with traditional microfabrication processes to turn them, for example, into metamaterials with novel optical properties.

Metal–organic frameworks (MOFs), composed of metal nodes coordinated with organic ligands, have emerged as a versatile class of functional materials for next‐generation smart textile systems. Their high surface area, tunable pore chemistry, and modular structural diversity enable multifunctional textile platforms. When integrated into textile substrates, MOFs can retain the properties, breathability, and comfort of fabrics while imparting advanced functionalities significant for sensing, environmental protection, biomedical interfaces, and energy‐related applications. This review provides a comprehensive overview of recent advances in MOF‐integrated smart textiles, focusing on material design principles, integration strategies, and application‐driven performance. Key fabrication approaches including surface coating, in situ growth, post‐synthetic modification, hydrothermal assembly, and emerging printing techniques such as inkjet and electrohydrodynamic jet are critically examined with respect to scalability, durability, and textile compatibility. Representative applications spanning gas and chemical sensing, detoxification, antimicrobial and biomedical functions, energy harvesting, and flexible energy storage are systematically discussed. Finally, current challenges and future opportunities are outlined, highlighting pathways toward scalable, durable, and application‐oriented MOF‐based smart textiles for real‐world applications.

Programming Quantum Hardware with DNA The cover illustrates the deterministic integration of single silver nanocluster emitters into a quantum computing architecture. By establishing a “Rule-of-10” threshold for DNA-templated metallization, in their Research Article (10.1002/sstr.202500822), Swati Tanwar, Ishan Barman, and co-workers achieve one-per-site growth with nanometer precision. This quantitative framework enables the scalable patterning of discrete photonic arrays, bridging the gap between bottom-up biological assembly and the next generation of chip-based quantum technologies.

Deciphering heterometallic synergy in the oxygen evolution reaction (OER) remains a challenge due to the structural complexity of traditional catalysts. We report a series of fluorinated metal–organic frameworks, M‐dfdmt (M = Fe, Co, Ni), featuring a “mercapto‐carboxyl” (mercarb) coordination motif that marries electrical conductivity with catalytic site accessibility. Within this architecture, soft thiolate groups establish deep M–S orbital hybridization for continuous charge transport, while labile [MO 6 ] units serve as primary active sites. While homoleptic Ni‐dfdmt exhibits high intrinsic conductivity (7.34 × 10 −4 S cm −1 ), the heterometallic NiFe‐dfdmt achieves superior OER activity. Theoretical charge population analyses, corroborated by X‐ray photoelectron spectroscopic binding energy shifts, reveal that coupling Ni and Fe induces a directed electron density shift and establishes local electric‐field gradients between heterometallic centers, which optimizes the electronic environment for intermediate adsorption. Kinetic studies, including a reaction order of 1.04 with respect to OH − , further support a lattice oxygen mechanism (LOM). By isolating heterometallic crosstalk within a crystallographically precise lattice, this work clarifies how electronically rewired coordination environments can modulate intermediate binding and facilitate charge transfer in molecularly defined electrocatalysts.

We report the realization of a two‐dimensional analog of the archetypical metal‐organic framework UiO‐66 as a Langmuir monolayer, constructed from preformed metal oxo clusters and amphiphilic terephthalic acid ligands at the air–water interface. Structural changes of the metal oxo clusters in aqueous solution were elucidated to clarify their role in interfacial self‐assembly at the water surface. Langmuir balance studies demonstrated that self‐assembly with specifically designed organic linkers proceeds through a coordination‐driven process. The resulting films were characterized by complementary techniques to determine their morphology, thickness, and composition. Based on these findings, a packing model of the monolayer was proposed. Finally, we extended this coordination‐driven self‐assembly strategy beyond aqueous systems to form, for the first time, monolayers at the air– N , N ‐dimethylformamide interface.

Ulcerative colitis (UC), a chronic inflammatory bowel disease, is hallmarked by persistent mucosal injury, oxidative stress, and dysregulated immune responses. Current therapies suffer from limited efficacy and systemic side effects, necessitating safer, targeted alternatives. Carbon dots (CDs) have emerged as versatile nanoplatforms, favored for their excellent biocompatibility and tailorable bioactivity. Inspired by the anti‐inflammatory and antioxidant properties of the traditional herb Scutellaria baicalensis , we developed herb‐derived CDs for targeted UC therapy. Three variants of CDs derived from Scutellaria baicalensis —namely, Carb‐CDs, Micro‐CDs, and Hydro‐CDs—were synthesized. Among these, Hydro‐CDs demonstrated superior performance, characterized by low cytotoxicity, strong reactive oxygen species (ROS) scavenging capabilities, enhanced superoxide dismutase (SOD)‐like activity, and improved anti‐inflammatory effects in macrophages. In the acute colitis model, Hydro‐CDs accumulated specifically in the inflamed colon tissues and markedly alleviated disease severity. Transcriptomic, KEGG, and Gene Set Enrichment Analysis (GSEA) analyses revealed Hydro‐CDs modulated critical signaling pathways (cAMP, calcium, and cGMP‐PKG), thereby reducing pro‐inflammatory cytokine secretion, upregulating tight junction protein expression, and restoring abnormal blood parameters. This study presents the inaugural synthesis of CDs derived from Scutellaria baicalensis and confirms their significant efficacy in UC treatment. It underscores the potential of herbal CDs as an innovative and synergistic nanotherapeutic approach for targeted intervention in inflammatory diseases, while also paving the way for the integration of natural medicinal components with nanotechnology.

Single‐atom engineering (SAE) is a promising approach for next‐generation rechargeable batteries due to its maximal atom utilization, high catalytic activity, and tunable selectivity. However, the incomplete understanding of the microenvironment of single atoms and their electrochemical behavior limits their practical application in rechargeable batteries. Most existing review articles either discuss battery chemistry or characterization techniques and rarely connect atomic‐scale defects, confinement, and coordination design to practical battery performance and its operando mechanism. This article provides an overview of SAE and examines both carbon‐ and metal‐based hosts, focusing on how microenvironment engineering influences electronic structure, charge transfer, active‐site stability, and energy efficiency. The major synthetic routes for constructing isolated and densely packed single‐atom sites are compared, and their advantages, limitations, and scalability are evaluated. Finally, it discusses applications of SAE in metal, metal‐ion, metal‐sulfur, and metal‐air batteries with an emphasis on metal nucleation, polysulfide/oxygen redox kinetics, and long‐term cycling, and integrates advanced ex situ and in situ/operando characterization with theoretical and data‐driven studies to clarify the dynamic structure–function relationships of single‐atom sites under battery cycling. Together, these perspectives provide a clear framework for designing robust, scalable next‐generation batteries based on SAE.

Acoustic Holograms In their Research Article (10.1002/sstr.202500354), Yifan Zhu, Hui Zhang, Badreddine Assouar, and co-workers report the concept of acoustic phase holographic imaging by metasurfaces that reveals the intrinsic coupling mechanism between amplitude and phase. They describe the governing equations for their dynamic coupling relationship, enabling phase holographic imaging acoustic communication with anti-attenuation and anti-interference properties. They furthermore experimentally demonstrate this new concept of phase holographic imaging.

Fluorescent organic nanoparticles (FoNPs) with backbone stiffness‐dependent photoluminescence were synthesized via microemulsion atom transfer radical polymerization (ATRP) of 2‐(2‐bromoisobutyryloxy)ethyl methacrylate (BiBEM), ethylene glycol dimethacrylate (EGDMA), and methacrylate monomers bearing pendant fluorophores, 1‐pyrenemethyl methacrylate (PyMMA), or 4‐(1,2,2‐triphenylethenyl)benzenemethyl methacrylate (TPEMMA). The crosslinking density precisely tuned the intraparticle rigidity, enabling systematic control over emission mechanisms. Pyrene‐containing FoNPs exhibited a rigidity‐dependent transition from excimer‐dominated to monomer‐dominated fluorescence, whereas TPE‐based FoNPs displayed aggregation‐induced emission (AIE) enhancement as intramolecular motion was restricted. Solvent‐dependent studies revealed that increased polarity and viscosity, particularly in benzyl alcohol and DMSO, promoted cooperative rigidification and enhanced emission intensity through specific polymer–solvent interactions. Furthermore, the retained alkyl bromide chain ends on FoNPs enabled dual roles as initiators and crosslinkers in UV‐induced polymerization of poly(ethylene glycol) acrylates, forming luminescent FoNP–OEG hybrid gels with improved mechanical robustness. This work establishes a versatile platform for integrating tunable optical and mechanical properties into a single polymeric nanoparticle framework, offering new design principles for multifunctional soft materials and providing a platform for future sensing, imaging, and photonic applications.