Topical glycopyrronium bromide is an acetylcholine receptor antagonist approved for the treatment of severe primary axillary hyperhidrosis in adults. The ointment is often prescribed off-label for hyperhidrosis on palms and soles. This case report presents ocular side effects after topical glycopyrronium bromide use, leading to several clinical follow-ups and diagnostic tests. This case report underscores the importance of recognising potential side effects for clinicians, especially in off-label treatment.

Thoracoscopic surgery is an alternative to open repair of congenital diaphragmatic hernia and oesophageal atresia. Studies show faster recovery compared with open approaches. Neonatal thoracoscopy was initially associated with longer operative times and higher complication rates. However, risks have declined with greater expertise, improved techniques, and careful patient selection. Neonatal anaesthetic management remains a demanding task and requires specialised skills. Thoracoscopy is now a safe option, though open surgery remains necessary in selected cases.

With this review, we aim to provide information about microvascular decompression in various forms of neurovascular conflicts between blood vessels and cranial nerves 7, 9, and 10 in the posterior fossa. Specifically, we will address the treatment of hemifacial spasms, glossopharyngeal neuralgia, and, in rare cases, vagus nerve involvement. We intend to disseminate this information widely to doctors in Denmark, as it is our impression that the diseases mentioned in the article are not well known to all doctors who encounter these patients, and the same applies to the treatment options.

This review investigates how recurrent colorectal cancer (CRC) affects ~16% of patients within 5 years after curative surgery and is linked to high mortality. Early dissemination and tumor dormancy challenge detection. Most recurrences occur in the liver, lungs, or peritoneum. Follow-up aims to detect early, but the survival benefits are uncertain. Around half of patients with recurrence may receive curative treatment, often involving surgery or chemotherapy. More research is needed to improve outcomes.

This review summarises studies on transgender individuals' satisfaction, regret, sexual well-being, and psychosocial outcomes after gender-affirming surgery. Qualitative studies with follow-up from months to years show satisfaction rates of 59-93% after top surgery and 61-88% after bottom surgery. Regret was low (0-4.7%). Several studies also reported improvements in mental health and quality of life, though many relied on non-validated and inconsistent outcome measures.

Irreparable rotator cuff tears show increasing incidence with age. In symptomatic cases, first-line therapy should be a minimum of six months of physical training, as many improve over time. Reparability is evaluated clinically and by MRI - assessing tendon retraction, fatty infiltration, and muscle atrophy. If symptoms persist, surgical treatment is considered: reverse shoulder arthroplasty is generally offered to older patients (> 60 years), while joint-preserving procedures such as tendon transfer or superior capsular reconstruction may be suitable for younger patients (less-than 60 years), as argued in this review.

Oral cavity cancer requires early recognition and multidisciplinary management. This review outlines key clinical signs, diagnostic pathways, treatment strategies, common complications, and rehabilitation. General practitioners and ENT specialists play a crucial role in early detection and follow-up. Treatment is primarily surgical, often followed by radiotherapy. Rehabilitation and quality of life are essential aspects of care. The review reflects current national guidelines and practice in Denmark.