Introduction: Community-acquired pneumonia (CAP) is a major cause of infectious disease mortality and a burden on healthcare systems.CURB-65 and Pneumonia Severity Index (PSI) scores assess disease severity and guide hospitalization decisions, but their role in predicting hospital stay remains unclear.This study evaluates the effectiveness of CURB-65 and PSI scores in predicting hospital stay and their utility in forecasting ICU admission and mortality. Materials and Methods:This retrospective study included adult CAP patients admitted to the Pulmonology Department via the Emergency Department between September 2021 and September 2022.CURB-65 and PSI scores were calculated, and their correlations with hospital stay, ICU admission, and mortality were analyzed using SPSS 20.0.Results: A total of 82 patients (median age 67.69 years) were included.Patients hospitalized 7 days had a median CURB-65 score of 1 and PSI score of 83, while those >7 days had a CURB-65 score of 2 and PSI score of 115.CURB-65 scores 2 were linked to prolonged stays (>7 days) in 70% of patients, compared to 41% in those 7 days.PSI scores also differed significantly between groups (p < 0.01).Moderate positive correlations were observed between hospital stay and both CURB-65 (r = 0.411) and PSI scores (r = 0.472).ROC analysis showed an AUC of 0.754 for PSI, with 84.8% sensitivity and 46.9% specificity. Conclusion:CURB-65 and PSI scores effectively predict hospital length of stay in CAP patients, aiding clinical decision-making and resource allocation.

Introduction:This study aimed to evaluate the clinical, obstetric, and perinatal outcomes of pregnant women with epilepsy and to investigate the impact of antiepileptic drug (AED) regimens (monotherapy versus polytherapy) on these outcomes. Materials and Methods:This retrospective study included 98 singleton pregnancies with epilepsy who delivered at a tertiary referral center between October 2022 and May 2025.Patients were grouped based on AED use: monotherapy or polytherapy.Composite adver se perinatal outcome (CAPO), including preterm birth, NICU admission, low Apgar scores, and neonatal complications, was the primary outcome.Univariate and multivariate logistic regression analyses were performed to identify factors associated with CAPO.Results: Among the participants, 76 (77.6%) received antiepileptic treatment; 60 (61.2%) received monotherapy and 16 (16.3%)received polytherapy.CAPO occurred in 37.8% of all cases, with a significantly higher rate in the polytherapy group compared to the m onotherapy group.Seizure during pregnancy, cesarean delivery due to fetal distress, and lower birth weight were more frequent in the polythe rapy group.In multivariate analysis, polytherapy was identified as an independent predictor of CAPO (aOR: 10.609; 95% CI: 1.617 -69.604), while higher gestational age at delivery was protective. Conclusion:This study revealed that cases of polytherapy resulted in significantly elevated incidence of seizures during pregnancy, cesarean sections due to fetal distress, low birth weight, and CAPO compared to monotherapy.The data suggest that the use of multiple antiepileptic drugs may adversely affect perinatal outcomes by increasing fetal exposure.

Familial Mediterranean Fever (FMF) is the most common autoinflammatory disease characterized by recurrent episodes of abdomin al pain, fever and serositis.FMF is an autosomal recessively inherited and self-limiting disease.It is more common in countries around the Mediterranean.Guillain Barre Syndrome (GBS) is an acute, immune -mediated polyneuropathy affecting peripheral nerves and nerve roots.GBS is usually characterized by progressive flaccid paralysis and decreased deep tendon reflexes .Central nervous system involvement is not common in the course of FMF.Guillain Barre Syndrome developed in a patient who was followed with colchicine treatment fo r 1 year due to Familial Mediterranean Fever.In the literature review, no association of these two dise ases was found.This case is presented to draw attention to the coexistence of immune-mediated Familial Mediterranean Fever and Guillain Barre Syndrome.In this case, it was thought that two inflammatory diseases may have affected each other or autoinflammatory diseases can be seen together.

IntroductionCOVID-19, also known as coronavirus disease 2019, is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).The disease was first identified in December 2019 in Wuhan, China, and has since spread globally, leading to a pandemic.SARS-CoV-2 is spread primarily through respiratory droplets and close contact with infected people (1).Common symptoms include fever, cough, fatigue and shortness of breath, although some infected individuals may be asymptomatic (1,2).The global pandemic had a profound impact on society, with significant disruption to travel, trade, education and health systems.In response to the crisis, a range of measures were implemented to control the spread of the disease, including social distancing, mask-wearing and vaccination campaigns (3,4).CRP: C-reactive protein (CRP) is a biomarker indicative of COVID-19 infection.Patients with COVID-19 exhibit elevated levels of CRP, a protein that increases in response to inflammation and infection.Although elevated CRP levels can be indicative of inflammatory diseases, including COVID-19, they lack specificity and can be elevated due to other infections and inflammatory conditions.In COVID-19 patients, CRP levels can offer valuable information regarding the severity and prognosis of the disease; however, they are not employed for diagnostic or monitoring purposes.Evaluated alongside other clinical findings and test results, CRP can aid in the comprehensive management of the disease (5,6).Ferritin: COVID-19 infection is associated with ferritin, a protein responsible for iron storage, which may increase during infection and

Introduction: Family physicians have an important role in the diagnosis and treatment of obesity, as most obese patients are first seen by the family physician.The aim of our study was to evaluate the obesity management of family physicians working in family heal th centers in Van province. Materials and Methods:This cross-sectional study was conducted between 04.05.2021-30.07.2021 with 126 volunteer family physicians working in family health centers representing Van province.The questionnaire including sociodemographic characteristics, obe sity knowledge and self-efficacy questions were completed by the physicians themselves.Results: Only 13 (10.3%) of the physicians knew the number of obese patients registered in their units.Although 97 (77%) of the physicians stated that the family physician was responsible for obesity management, 54 (42.9%) stated they calculated the body mass index of their patients "sometimes" and 48 (38.1%) "rarely".Seventy-one (56.3%) of the physicians thought family physicians had a great role in the prevention of obesity, while 63 (50%) argued the best role of the family physicians in obesity management isn't treating these patients but referring them to the relevant fields.Among physicians who calculated BMI "often", 6 6.7% indicated that they were professionally prepared to treat overweight patients and didn't consider themselves unsuccessful in getting their patients to lose weight. Conclusion:Our study shows that although obesity is included in chronic disease follow -up in primary care, it has not been put into practice.It is clear that there is a need to train family physicians on obesity management and to help them gain self -efficacy.

vermian agenesis, mega cisterna magna), vascular malformations, corpus callosum (CC) agenesis constitutes CNS anomalies (5).Ultrasonography (US) is the primary and most frequently used diagnostic tool for detecting CNS anomalies (6).Major processes such as neuronal proliferation, migration or organization in the CNS developmental process occur in the second half of pregnancy.However, most of the CNS anomalies can be detected with a detailed US evaluation performed during the 18-20 weeks of pregnancy.(7).Fetal Magnetic Resonance Imaging (MRI),

Ama: Bipolar bozukluk(BB), mani ve depresyon dnemleriyle karakterize arada dzelmelerin olduu kronik bir bozukluktur.Son zamanlarda Bipolar bozukluun(BB) patofizyolojisinde inflamatuar sistem zerinde durulmaktadr.Ortalama trombosit hacmi(MPV), trombosit dalm genilii(PDW) ve eritrosit dalm genilii(RDW) inflamasyon dzeyini lmek iin nerilen, olduka ucuz hematolojik biyobelirtelerdir.Psikiyatri d hastalklarda bu belirtelerle ilgili ok sayda alma

Sella turcica, which keeping the pituitary gland inside, is frequently used in cephalometric analysis during the orthodontic treatment planning because it can be easily detected in lateral cephalometric radiographs. Embryologically, the cartilage forming the anterior wall of the sella turcica develops from the neural crest cells. Similarly, it has been reported that the dental epithelial progenitor cells and maxillary, palatal and frontonasal development regions also generated from neural crest cells and these cells are effective in sella turcica bridging and tooth development and eruption. Thus, in the literature, the variations in sella turcica dimensions and morphology has been associated with different craniofacial and dental anomalies due to its relationship with pituitary gland, development origin, and anatomic position. At this point, the correct analysis of sella turcica, provide early diagnosis of the anomalies and pathologies that can be arise in the future. However, it has been observed that conflicting results were obtained from these studies in which subjects with different ethnical origin, age, and craniofacial morphologies were evaluated and different radiographic techniques were used. In this review, it was aimed to examine these studies which were evaluated the association of sella turcica dimensions and morphology with different craniofacial and dental anomalies.

Introduction:This study aimed to investigate the correlation between the modified and the classical methods in carpal tunnel syndrome (CTS) diagnosis. Materials and Methods:The study included a total of 275 hands of 188 patients.First, the patients with CTS complaints were diagnosed according to the classical and the modified methods.Then, it was investigated whether there was a correlation between these two methods.The correlation agreement analysis between two methods was evaluated with the Kappa test. Results:In present study, it was found that 155 hands were (80 mild + 75 moderate) diagnosed with CTS, and 137 patients were female (85.2%).Moreover, it was detected that the modified method had a sensitivity of 90% and specificity of 97% regarding the classical method.In diagnosing moderate CTS, the modified method showed a high sensitivity and specificity (98.6% -100%, respectively). Conclusion:In conclusion, a near-perfect agreement was found between the modified and the classical methods for the diagnosis of CTS.

INTRODUCTION: It is important to detect endometrial cancer (EC) in endometrial intraepithelial neoplasia (EIN) patients. It was aimed to determine the role of systemic immune inflammation index (SII) in predicting concurrent EC in women with EIN. METHODS: In this retrospective study, 429 women with EIN divided into three groups according to final histopathologic results: benign(n=151), EIN(n=152), and EC(n=126). Demographic and clinical data, pathologic and laboratory result were collected. Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and SII index were calculated and compared among groups. RESULTS: The SII, PLR and NLR values of benign, EIN and EC groups were compared and all values of EC group were the highest. The ROC analysis showed that although all markers had statistical significance, the AUC of SII was the highest. The SII score&gt;0.67 (95%CI: 7.17-37.3) had a 16.35-fold, preoperative platelet count &gt; 287 (95%CI: 1.91-6.2) had a 3.45-fold and age &gt;49 years (95%CI: 1.97-5.92) had 3.42-fold increased risk for EC. DISCUSSION AND CONCLUSION: Although age and preoperative platelet count were found independent risk factors, SII was the strongest predictor for EC in women with EIN. SII can be used as a predictive marker for identifying concurrent EC or having risk for developing EC in women with EIN.