Background Climate change is increasing the frequency and severity of heatwaves across South Asia, with disproportionate impacts on vulnerable populations. Pregnant and lactating women face heightened health risks due to physiological changes, gendered social responsibilities, and constrained access to adaptive resources. Despite this, women’s lived experiences and adaptation practices during pregnancy remain understudied and largely absent from institutional climate responses. This knowledge gap hampers the development of effective, gender-sensitive adaptation policies. Methods This qualitative study, embedded within the Heat in Pregnancy (HiP)-India project, will be conducted in three climatically vulnerable sites: Gurugram (Haryana), Bilaspur (Chhattisgarh), and Puducherry. Guided by a socio-ecological framework, we will conduct in-depth interviews with pregnant and lactating women, focus group discussions with caregivers, and key informant interviews with health workers and local stakeholders, alongside non-participant observations. Interviews will take place during and shortly after the heat season to capture both real-time and reflective experiences. Using purposive sampling, we will recruit 20–25 women per site, along with caregivers and stakeholders, primarily from the HiP-India cohort who have consented to follow-up. Data will be thematically analysed using NVivo, with reporting guided by COREQ standards. Anticipated Results The study will generate contextualised insights into women’s heat-adaptation practices during pregnancy and lactation across diverse agro-climatic zones, document traditional and emerging coping strategies, and identify structural, social, and institutional barriers shaping adaptation capacity. Conclusion By centering women’s lived experiences, this research will inform the design of culturally appropriate, gender-responsive heat adaptation interventions suitable for low-resource settings. Findings will support both practical community-based solutions and evidence-based advocacy for more inclusive climate adaptation policies at local and national levels.

Due to the proliferation of new SARS-CoV-2 variants, most COVID-19 cases are now caused by post-vaccine infections and a substantial proportion are reinfections. While prior research on correlates of protection has focused on the role of anti-spike antibodies, the results of the corresponding antibody assays may not accurately predict the risk of infection with new SARS-CoV-2 variants. In this study, we investigated the association between live virus neutralising antibody activity and SARS-CoV-2 infection risk using self-administered capillary microsample blood tests from VirusWatch participants. The study was conducted during the transition between the dominance of the B.1.617.2 (Delta) and B.1.1.529 (Omicron BA.1) SARS-CoV-2 variants, enabling us to investigate the association between variant-specific virus inhibition and subsequent infections within each dominance period within a test-negative study design. Greater inhibition of Omicron BA.1 live virus was associated with a reduction in infection risk during both the Delta and Omicron BA.1 dominance periods. Delta virus inhibition was associated with infection risk reduction during the Delta dominance period, but we found no association between Delta inhibition and protection against infection during the Omicron BA.1 dominance period. Our results are consistent with earlier findings and suggest that variant-specific serosurveillance of immunity and protection against SARS-CoV-2 infection at the population level could inform public health policy in near-real time using inexpensive and accessible home-based testing.

We present a genome assembly from an individual female Venturia canescens (ichneumonid wasp; Arthropoda; Insecta; Hymenoptera; Ichneumonidae). The genome sequence has a total length of 299.96 megabases. Most of the assembly (97.25%) is scaffolded into 11 chromosomal pseudomolecules. The mitochondrial genome has also been assembled, with a length of 27.35 kilobases. Gene annotation of this assembly on Ensembl identified 14 281 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

We present a genome assembly from an individual Echiichthys vipera (Lesser weever; Chordata; Actinopteri; Perciformes; Trachinidae). The genome sequence has a total length of 800.38 megabases. Most of the assembly (99.21%) is scaffolded into 25 chromosomal pseudomolecules, including the X and Y sex chromosomes. The mitochondrial genome has also been assembled, with a length of 16.92 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces genome assemblies for eukaryotic species found in Britain and Ireland.

We present a genome assembly from an individual female Rutpela maculata (a longhorn beetle; Arthropoda; Insecta; Coleoptera; Cerambycidae). The genome sequence is 2,021.6 megabases in span. Most of the assembly is scaffolded into 10 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 17.84 kilobases in length. Gene annotation of this assembly on Ensembl identified 14,238 protein-coding genes.

We present a genome assembly from an individual female Atolmis rubricollis (Red-necked Footman; Arthropoda; Insecta; Lepidoptera; Erebidae). The assembly contains two haplotypes with total lengths of 647.88 megabases and 585.85 megabases. Most of haplotype 1 (99.59%) is scaffolded into 32 chromosomal pseudomolecules, including the W and Z sex chromosomes. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 15.43 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

The aim of this data note is to describe data collected in 2022 on sexual history, attitudes, enjoyment and regret. Data were collected from mothers (age range 47-75 years (mean 60.0), n = 4653) their partners (age range 47-83 years (mean 62.9), n= 1945) and offspring (aged ~30 years, females n= 2702, males n=1366) in the Avon Longitudinal Study of Parents & Children (ALSPAC). Many of the questions asked are identical, or similar, to those collected in the British NATSAL (National Surveys of Sexual Attitudes & Lifestyles). Repeating the same questions in both ALSPAC generations allows for direct inter-generational comparisons within ALSPAC as well as across studies. Areas covered include age at sexual debut; having drunk alcohol, used drugs or contraception at sexual debut; the circumstances under which participants met their first sexual partner; sexual orientation; the Brief Sexual Attitudes Scale; regret at first sexual experience, lifetime experiences of sexual regret and the degree of regret, as well as the reason(s) for that regret; number of sexual partners both in the last two years and over their lifetime; current frequency and enjoyment of sex. ALSPAC provides a rich resource of data collected on a wide variety of topics including details of the participants' environment, lifestyle, physical and mental health over the life span, including sexual experiences collected retrospectively from the parents, and from the age of 11 in the offspring. There are thus many opportunities for research on a wide variety of topics related to potentially risky and normal sexual behaviours, sexual health, functioning and well-being.

We present a genome assembly from an individual male Propylea quattuordecimpunctata (14-Spot Ladybird; Arthropoda; Insecta; Coleoptera; Coccinellidae). The genome sequence has a total length of 579.30 megabases. Most of the assembly (96.58%) is scaffolded into 10 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled, with a length of 19.07 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

<ns3:p> We present a genome assembly from an individual female <ns3:italic>Crepidodera fulvicornis</ns3:italic> (leaf beetle; Arthropoda; Insecta; Coleoptera; Chrysomelidae). The genome sequence has a total length of 493.21 megabases. Most of the assembly (99.53%) is scaffolded into 9 chromosomal pseudomolecules. The mitochondrial genome has also been assembled, with a length of 19.7 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland. </ns3:p>

We present a genome assembly from an individual <i>Chelidonichthys lucerna</i> (tub gurnard; Chordata; Actinopteri; Perciformes; Triglidae). The assembly contains two haplotypes with total lengths of 649.07 megabases and 651.58 megabases. Most of haplotype 1 (96.66%) is scaffolded into 24 chromosomal pseudomolecules. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled, with a length of 16.52 kilobases. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.