- Research Article
- 10.25258/ijpqa.17.1.43
Computed Tomography Evaluation of Acute Pancreatitis and Its Prognostic Correlation with the CT Severity Index
- Jan 30, 2026
- International Journal of Pharmaceutical Quality Assurance
- Arbind Kumar Singh + 1 more +1
Background: Acute pancreatitis (AP) is an acute inflammatory condition of the pancreas with a wide spectrum of clinical severity, ranging from mild disease to severe forms associated with complications and mortality. Early assessment of disease severity is essential for effective management. Contrast-enhanced computed tomography and the CT Severity Index are widely used imaging tools for evaluating pancreatic inflammation, necrosis, and predicting clinical outcomes. Objective: To evaluate the role of CECT in patients with acute pancreatitis and determine its prognostic correlation with the CT Severity Index. Methods: This prospective observational study was conducted in the Department of Radiology, Sadar Hospital, Lakhisarai, Bihar, India and Sonoscan Pvt.Ltd, Malda, West Bengal, India. over a period of 8 months. A total of 80 patients diagnosed with acute pancreatitis based on clinical and laboratory findings were included. All patients underwent CECT abdomen within 72 hours of symptom onset. CT findings were assessed for pancreatic inflammation, necrosis, and peripancreatic complications, and CTSI scores were calculated. Clinical outcomes including hospital stay, organ failure, ICU admission, and mortality were recorded and correlated with CTSI. Results: Gallstones (45%) and alcohol (35%) were the most common etiological factors. Most patients had mild to moderate diseases based on CTSI. Higher CTSI scores were significantly associated with longer hospital stay, increased complications, ICU admission, and mortality. Conclusion: CECT with CTSI is a reliable imaging modality for early diagnosis, severity assessment, and prognostic evaluation in acute pancreatitis, aiding clinicians in risk stratification and appropriate management.
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