Beijing Royal Integrative Medicine Hospital

Background Fever is a common clinical manifestation following acute myocardial infarction(AMI). However, differentiating its etiology-specifically, distinguishing between fever caused by the absorption of necrotic tissue and fever due to concurrent infection is critical, as this distinction directly influences treatment decisions and patient prognosis. Methods This retrospective study reviewed AMI patients from two centers. Participants were divided into two groups: a fever of non-infectious origin group and patients with fever secondary to infection.We initially identified candidate risk factors demonstrating significant differences, Then,a stepwise selection technique was applied to potential univariate correlates (P < 0.1) to construct a multivariable risk score model. Results 69 out of 1507 AMI patients were included, with 32 patients (46.4%) presenting AMI complicated by infection and 37 patients (53.6%) having AMI without infection but presenting with fever.Twelve dichotomous characteristics were screened as candidate predictor variables. Using stepwise elimination, four independent predictors were retained in the final logistic model: age, peak body temperature (BT), baseline platelet count, and peak CRP. Multivariate analysis identified the following independent predictors:age (OR=1.11, 95% CI: 1.041-1.186), peak BT (OR=9.83, 95% CI: 1.954-49.441), baseline platelet count (OR=1.01, 95% CI: 0.999-1.029), and peak CRP (OR=1.01, 95% CI: 0.998-1.026).A risk score was calculated by assigning points to categorized levels of each predictor weighted by their respective regression coefficients. The scoring distribution were: age (0,1,2,3,4,5 points), peak BT (0, 1, 3, 5 points), baseline platelet count (0, 1, 3, 5, 6 points), and peak CRP (0, 1, 2 points), which ranged from a minimum of 0 to a maximum of 18 .The score could predict the risk of infection with good discriminative ability (AuROC: 0.899, 95% CI: 0.823-0.975 P=0.000) in fever of AMI patients. Conclusions We first demonstrate that a simple bedside score incorporating BT, CRP, platelet count, and age can effectively discriminate between sterile inflammatory fever and infectious fever in patients with AMI.

Gastric cancer remains a global health burden due to its late diagnosis and poor prognosis. Conversion therapy aims to make the initially unresectable tumor resectable through systemic treatment, providing the opportunity for long-term survival. The rise of immunotherapy has brought new potential to this field. Immunotherapy combined with chemotherapy, anti-angiogenic drugs or chemoradiotherapy has shown good efficacy in specific patients. This review summarizes the current evidence of conversion strategies based on immunotherapy, emphasizes key biomarkers, and explores the future direction of precise, multi-modal treatment.

With the slow decline of the epidemic's influence on people's lives, numerous international sporting events eventually recommenced. Within this particular framework, the Qatar 2022 FIFA World Cup has progressively captured the attention of the general public. This event serves as both a recreational activity and a commemoration of liberty, athletics, and well-being. This research focuses on the examination of the fan violence community during the 2022 FIFA World Cup in Qatar, with a particular emphasis on dysfunctional fans. This report uses event review and bibliometrics as its research approach. An extensive body of existing research literature was utilized to investigate the factors contributing to the decline in fan violence during the Qatar World Cup. In the end, it was determined that the issue was connected to the British government's prohibition of passports and the implementation of widespread surveillance. Nevertheless, due to the temporal gap of one year after the occurrence and the nascent stage of the research, the derived results lack reliability.

Many scholars have previously studied the birth rate and its development, but there are still gaps in the research on which factors play a dominant role in the birth rate. Therefore, this paper will provide a clear study of this issue, using China as an example to help major countries solve the problem of low birth rates and economic development. The population issues caused by low birth rate were researched and the main factors for birth rate were found from research. The decisive factors that determine the birth rate in China were analyzed. The link between birth rate and economic development is examined. This study figures out that the two main factors that influence the birth rate are the divorce rate and the female employment rate. There is a relatively strong correlation between the birth rate and economic development. The formula and the principle of Vector Autoregressive (VAR), Bayesian Information Criterion (BIC) and Times Series Graphical lasso (TSGlasso), were researched and used.

Hantaviruses have always existed in today’s society, and people in many countries have been attacked by rodents, or unknowingly in contact with rodent fluids, leading to a silent increase in the number of hantavirus cases. Compared to the current COVID-19 epidemic, the hantavirus is not well known to the world, but in fact, not only in the United States but in China, HFPS cases account for more than half of the confirmed cases globally. Both HPS and HFPS can lead to severe clinical features such as hypotensive shock, renal failure, and other symptoms. At present, there is no specific medicine, and the vaccine technology is not mature. Vaccines are still in development and have not yet reached the ideal state. So, this essay is to summarize the past surveillance and control of the hantavirus in the United States to reduce the possibility of a resurgence of the virus. By explaining the cases of hantavirus in the United States and the work, race, gender, and many different aspects of the patients, the current treatment direction and methods of hantavirus are explained. On the whole, people should pay more attention to epidemic monitoring, strengthen customs management, strengthen people's awareness of the hantavirus, and strengthen education in high-risk areas, to be more able to control the outbreak of the epidemic.

Obesity is a chronic disease that endangers human health. In recent years, the phenomenon of obesity has become more and more common, and it has become a global epidemic. Obesity is closely associated with many adverse metabolic changes and diseases, such as insulin resistance, type 2 diabetes mellitus, coronary heart disease, nervous system diseases and some malignant tumors, which have caused a huge burden on the country’s medical finance. In most countries of the world, the incidence of cancer caused by obesity is increasing year on year. Diabetes associated with obesity can lead to secondary neuropathy. How to treat obesity and its secondary diseases has become an urgent problem for patients, doctors and society. This article will summarize the multidisciplinary research on obesity and its complications.

Objective: To investigate the clinical efficacy of the combination of enhanced “Shou Tai Wan” soup and progesterone in the treatment of early pre-eclampsia miscarriage. Methods: 86 patients with early pre-eclampsia miscarriage in our hospital from July 2021 to July 2022 were selected and randomly divided into two groups of 43 cases each. The control group was treated with progesterone, while the study group was treated with an addition of enhanced “Shou Tai Wan” soup. The treatment effects of the two groups and the changes in the inflammatory factor levels and sex hormone levels before and after the treatment were observed. Results: INF-? and Il-2 were lower and IL-4 was higher in the study group than in the control group after treatment (p-value < 0.05); the total effective rate of treatment was higher in the study group (95.35%) than in the control group (74.42%), (p-value < 0.05); the levels of P, E2 and ?-hCG were higher in the study group than in the control group after treatment (p-value < 0.05). Conclusion: The combined application of enhanced “Shou Tai Wan” soup and progesterone in patients with early preterm abortion is more effective by improving the patients’ sex hormone levels and reducing the level of inflammatory factors, which is conducive to the improvement of the treatment effect and worthy of promotion.

Abstract Backgrounds: The health of university staff is a major occupational health concern worldwide. Studies have reported low health-related quality of life (HRQOL), low job satisfaction and poor mental health in this occupational group. However, none of previous studies have measured health utility and compared it to a national norm. Therefore, this study was conducted to gain a deeper understanding of the HRQOL of university staff in China and to identify risk factors influential to their health. Methods: This was a cross-sectional survey conducted in a public university in China. Participants were interviewed face-to-face for demographic and socioeconomic information and health conditions. The Chinese version of the EQ-5D-5L instrument was used to measure HRQOL for calculating health utility. The relationship between health utility and sample characteristics was first examined using t-test and correlation analysis. Multivariate generalized linear models were further applied to evaluate the significance of these associations while adjusting for other variables. Results: The sample (n=154) had a mean age of 40.65 years and slightly more females (51.30%). The overall prevalence of diseases or symptoms was 81.17%. Participants attained the means (SDs) of 0.945 (0.073) and 83.00 (11.32) for the health utility and visual analogue scale respectively. The most affected domain was the anxiety/depression with 40.26% of participants reporting problems and 37.66% of the sample reported problems in the pain/discomfort domain. There were less than 5% participants reported problems in the mobility, self-care or daily activity domains individually. Multivariate models revealed that psychological/emotional conditions were associated with the largest utility loss of -0.067 (95%CI: -0.089, -0.045) followed by having a Master’s degree or higher (-0.048, 95%CI: -0.09, -0.005) and pain in body parts other than head, neck and back (-0.034, 95%CI: -0.055, -0.014).Conclusions: University staff in China may have worse HRQOL than the general population, which manifested mainly with the pain/discomfort and anxiety/depression domains. The significant factors for utility loss were having a Master’s degree or higher, psychological conditions and pain in body parts other than the head, neck and back. Targeted health promotion policies and programs should be created to benefit this occupational group and society overall.

Aims To explore the relationships of procollagen type 1 N-terminal propeptide (P1NP) and β cross-linked C-telopeptide of type 1 collagen (β-CTX) with bone mineral density (BMD) in postmenopausal women. Methods All postmenopausal women were selected from a community-based case-control study. The anteroposterior L1-L4 and left proximal femur BMD were measured. P1NP and β-CTX were also collected and tested. The main correlation analysis was applied to explore the relationships of BMD, P1NP, and β-CTX. Results The total 1055 postmenopausal women were enrolled. The BMD at all sites kept a decrease continually with age (P < 0.01). In addition, the level of β-CTX increased significantly from 45 to 50 years old and remained at a high level in the later stage, while the level of P1NP changed little or even decreased with age. Logistic regression model showed that β-CTX has better ability to predict BMD than P1NP, as demonstrated by an area under the curve (AUC) of 0.63. Conclusion P1NP and β-CTX are important markers to monitor bone metabolism. This trial is registered with ChiCTR-SOC-17013090. The date of registration is Oct. 23, 2017.