Centro Universitario Toledo

Background/Objectives: The consumption of ultra-processed foods (UPFs) has increased markedly in recent decades and has been associated with adverse health outcomes. In childhood, the family environment plays a central role in shaping dietary habits and oral health behaviors. This study investigated the association between UPF consumption by caregivers and children, its relationship with caregivers' periodontal health-related quality of life, and described children's dietary practices and oral hygiene habits. Methods: This cross-sectional study was conducted with caregivers of children participating in the Happy Smile Project in Birigui, São Paulo, Brazil. UPF consumption was assessed using a questionnaire based on the NOVA classification, and periodontal health-related quality of life was evaluated using the OHIP-14-PD. Results: A high frequency of UPF consumption was observed among both caregivers and children. Children whose caregivers had high UPF consumption were more likely to also present high consumption (OR = 9.96; 95% CI: 5.38-18.44; p < 0.001). Higher caregiver education was associated with lower odds of high UPF consumption among children. Children in the high-consumption group were older and showed higher consumption of sweetened milk beverages (p < 0.001). Risk behaviors for oral health, such as nighttime use of sweetened bottles and absence of toothbrushing afterward, were frequently reported. Regarding periodontal health-related quality of life, only the physical disability domain showed significantly higher scores among caregivers with high UPF consumption (p = 0.014). Conclusions: This study demonstrated that high consumption of ultra-processed foods by caregivers significantly increased the odds of children's consumption and was associated with a greater negative impact on caregivers' periodontal health-related quality of life, specifically in the physical disability domain. In addition, children exhibited a high frequency of oral health-damaging behaviors. These findings highlight the importance of family-centered strategies aimed at reducing the intake of ultra-processed foods and promoting healthier dietary and oral health behaviors.

To evaluate the financial applicability of the DNA-HPV test for cervical cancer screening in a developing country like Brazil. This was a retrospective, observational study based on documentary data, conducted to assess the cost-effectiveness of cervical cancer screening strategies in Brazil. The study used national cervical cancer screening data collected between January 1 and December 31, 2020 for women between 25 and 64 years old, performing a cost-effectiveness assessment of two different screening tests. No sensitivity analysis was conducted due to the descriptive nature of this preliminary cost assessment. Based on the cervical smear, the Brazilian protocol has an estimated cost of US$117.5 million. In contrast, when using the HPV DNA test, the estimated cost is US$1.39 billion. The current use of the cervical smear is the least expensive and the only one that aligns with Brazil's financial resources allocated to health.

The aim of this study was to evaluate the linear and volumetric measurements of the frontal sinus (FS), using cone beam computed tomography (CBCT) scans, for a discriminatory analysis of gender, age and facial skeletal pattern in a Brazilian population. A total of 300 CBCT scans were analyzed, measuring the height, width, length and volume of the FS. The measurements were divided into groups: sex, age (<20 to >40 years and >40 years) and facial skeletal pattern classes I, II and III. The function values in the centroid group were 0.675 for male and -0.292 for female. A rule was established indicating that if the value of D is greater than 0.19, the sample will be classified as male. The results showed a significant difference in women, who had significantly lower volume, width and depth than men (p-value<0.001, 0.003 and <0.001 respectively). No significant differences could be observed between the age and facial skeletal pattern groups. The results suggest that the FS measures of volume, height, width and depth have moderate discriminatory power for predicting gender in a Brazilian population. In conclusion, the results show that the FS has potential for determining gender, but the accuracy of the method and its applicability for analyzing age and facial skeletal pattern were limited in our population.

Although dental surgeons implemented effective measures to minimize contamination risks, continuous training and awareness strategies remain essential to enhance protection in dental settings.

Calcium silicate-based sealers are bioactive materials that release ions when in contact with body fluids. Therefore, this study aims mapping/trace bone formation markers released by MTA Fillapex, BioRoot RCS, and experimental tricalcium silicate-based sealer (CEO) into subcutaneous tissues, bloodstream and body organs. Toward, polyethylene tubes filled with sealers were implanted into connective tissue of Wistar rats. On days 7, 15, 30, and 45 after implantation, blood samples were collected to measure calcium (Ca2+), phosphorus (P), and alkaline phosphatase (ALP) levels. Thereafter, the animals were killed, and the brain, liver, kidneys, and subcutaneous tissue were removed and processed to determine the concentrations of Ca2+ and P by ICP-OES. Similar Ca2+ levels were observed in subcutaneous tissue for all groups, although, at 45days, it was identified a reduction in Ca2+ serum levels of CEO compared to those two other sealers and an increase in Ca2+ levels in the liver compared to those released by MTA Fillapex. In contrast, no trace of P was detected in any tissue; moreover, plasma P and ALP serum levels of MTA Fillapex were higher at day 30. Our findings showed that Ca2+ were identified in local tissues, bloodstream, and organs from all sealers. The up-regulation of bone marker levels promoted by sealers can modify body homeostasis and induce tissue damage. Besides, MTA Fillapex was associated with a raise of bone marker levels, suggesting a possible systemic effect. The sealer composition can affect not only the local repair process but also the systemic health.

O presente artigo analisou o impacto no Orçamento Geral do Estado (OGE) durante a pandemia da covid-19. Foram examinadas as despesas na saúde em diversos Grupos de Natureza de Despesa (GND) entre 2015 e 2022, com dados do Business Intelligence (B.I.) extraídos do Sistema Integrado de Execução Financeira e Orçamentária dos Municípios (SIAFEM). A pesquisa é descritiva e usa uma abordagem quantitativa para analisar os gastos públicos relacionados ao combate à covid-19 no planejamento orçamentário da saúde no Pará. O estudo encontrou um aumento nas despesas de investimentos e custeio da máquina pública com serviços de saúde pós-pandemia, contrariando a expectativa de redução. Os gastos em saúde têm um impacto abrangente, contribuindo significativamente para vários ODS, especialmente o ODS 3, que está diretamente relacionado à resposta à covid-19. Este estudo buscou identificar o impacto nos gastos públicos com despesas decorrentes do combate à pandemia da covid-19. Naturalmente se pensava no arrefecimento dos gastos com saúde pública, mas se encontrou uma outra realidade de incremento de investimentos e custeio da máquina pública com serviços públicos de saúde pós-pandemia.

A dor é uma experiência comum que afeta a vida das pessoas de formas variadas, estando presente nos hospitais de forma extensa. Os opioides são recorrentemente utilizados para tratamento de dores intensas constantes, em especial na dor nociceptiva, que está associada a danos teciduais, como em pós-cirúrgicos e traumas severos. Embora o uso dos opioides demonstrem eficácia no alívio da dor intensa, o uso prolongado pode acarretar danos à saúde, como depressão respiratória e redução da motilidade gástrica. Porém, os efeitos mais preocupantes quando se trata de opioides são a tolerância, a dependência e a hiperalgesia. Portanto, a prescrição desses medicamentos deve ser monitorada e adaptada para minimizar os potenciais riscos e otimizar o tratamento. Dessa forma, o objetivo da pesquisa consiste em identificar e conhecer o perfil terapêutico dos prontuários médicos sobre o uso de analgésicos opioides em um hospital localizado na região oeste do Paraná. A metodologia desta pesquisa trata-se de uma pesquisa exploratória de abordagem qualitativa e quantitativa, caracterizada pela natureza descritiva, por meio da análise de prontuários médicos. Durante a pesquisa foram analisados 198 prontuários, dos quais 100 constavam o registro do uso de opioides. Observou-se que os opioides prescritos com maior frequência foram: tramadol, fentanil e morfina. Um outro dado relevante identificado está relacionado com a prevalência de 61% de pacientes do gênero feminino com idade de 29-39 anos. Observou-se também que a principal associação entre opioides está relacionado com a administração dos medicamentos fentanil e tramadol. Os resultados ressaltam a necessidade de estratégias visando uma prescrição mais consciente, considerando alternativas não opioides sempre que possível. Destaca-se a importância da vigilância continua dos profissionais da saúde para garantir a eficácia do tratamento e minimizar potenciais riscos devido ao uso de opioides.