Centro de Estudos do Laboratório de Aptidão Física de São Caetano do Sul

BackgroundImmunization against pneumococcal disease (PD) for individuals with certain coexisting health conditions is guided by the recommendations of the National Immunization Program (NIP) in the Unified Health System (SUS) in Brazil. There are uncertainties regarding the size of the population at risk of PD in Brazil and the proportion of high-risk individuals that are assessed at the Reference Centers for Special Immunobiologicals (Centros de Referência para Imunobiológicos Especiais, CRIE). Objectives were to assess the high-risk population size by using the outpatient claims database of Brazilian National Health System (SUS), and to estimate vaccination coverage rates.Box 1:High-Risk Groups as defined by the National Immunization Program (NIP) in the Unified Health System in BrazilFigure 1:Number of distinct individuals at high risk for pneumococcal disease by health condition, logarithmic scaleMethodsICD-10 and procedure codes related to high-risk health conditions, as defined by the NIP (Box 1) were defined, together with proxies of disease activity and severity. Data from DATASUS-SIA, the outpatient information system of medium-to-high complexity levels of care in the SUS, and the information system of immunobiologicals (SI-PNI) were analyzed. Encrypted identifiers were used to allow for the counting of distinct individuals from November 2021 to October 2023. Complete vaccination schemes were defined as having received at least one PCV13 and two or more PPS23 doses; incomplete vaccination schemes as one PCV13 and less than two PPS23 doses; and non-conforming vaccination schemes as more than one PCV13 and less than two PPS23 doses.ResultsEstimated size of the high-risk population was 1,609,181 individuals (Figure 1). Coverage rate for having received at least one dose of PCV13 was estimated at 45.5% and for the complete vaccination scheme at 3.5% of the high-risk population. Among vaccinated individuals, most received incomplete (N= 249,132, 34%) or non-conforming vaccination schemes (427,940, 58.4%), while a minority received the complete vaccination scheme (n=55,595, 7.6%) (Table 1).ConclusionA small proportion of high-risk individuals was estimated to have received the complete pneumococcal vaccination scheme, possibly due to the high complexity of the vaccination scheme, and limited access to CRIE, considering the continental size of Brazil and the concentration of CRIE in large cities. These findings should be considered in the design of vaccination strategies targeting PD in SUS.DisclosuresRicardo Macarini Ferreira, Md/ MBA, Pfizer Brazil: Employee Daniela V. Pachito, MD PhD MBA, Pfizer: Employee|Pfizer: Stocks/Bonds (Private Company) Paulo Almeida, PhD, Pfizer Brazil: Employee

Introdução: A análise do número de passos tem sido associada com diversas variáveis relacionadas à saúde de idosos, na aptidão física, composição corporal, capacidade funcional e sua redução está relacionada com diversas doenças crônicas não transmissíveis. A redução do número de passos/dia está associada com desfechos negativos na composição corporal, desenvolvimento de doenças e risco de morte por câncer. Objetivo: Determinar o perfil de aptidão física e capacidade funcional de acordo com o nível de atividade física avaliados de mulheres adultas praticantes de atividades físicas. Métodos: Participaram deste estudo 159 mulheres praticantes regulares de atividade física com idade entre 50 a 86 anos (69,55±7,9 anos) participantes do Projeto Longitudinal de Envelhecimento e Aptidão Física de São Caetano do Sul. O nível de atividade física foi mensurado pelo número de passos, por pedômetro (Digiwalker C 700/SW 200), por sete dias consecutivos. A avaliação da aptidão física foi realizada pela força de membros superiores e inferiores e agilidade. A capacidade funcional foi mensurada pela mobilidade e equilíbrio. A análise estatística utilizada foi ANOVA One-Way, seguido de Post Hoc Bonferroni e nos dados não paramétricos utilizou-se os testes de Kruskal-Wallis e Mann-Whitney. O número de passos foi dividido em tercil (tercil 1 < 5.618 passos/dia; tercil 2 5.619-9.054 passos/dia e tercil 3 > 9.055 passos/dia). O nível de significância adotado foi de p<0,05. Resultados: Foi encontrado que o tercil 3 resultou em diferenças estatisticamente significantes nas variáveis antropométricas: peso, IMC, circunferência de cintura e circunferência de quadril, variáveis neuromotoras: força de membros inferiores e agilidade e na capacidade funcional em mobilidade geral e locomoção. Conclusão: mulheres que se encontram com o padrão de passos diários superior a 9050 obtiveram melhor perfil de aptidão física e capacidade funcional.

A pandemia do COVID-19 apresentou-se como grande problema de saúde pública para o Brasil e o mundo. Ela teve impacto em indicadores de saúde, como morbidade, mortalidade e gastos com saúde, além de impactos econômicos importantes relacionados ao fechamento de estabelecimentos e o isolamento social. Diante desse cenário, essa pesquisa foi proposta para o município de São Caetano de Sul (São Paulo) com o objetivo de analisar a relação entre comportamentos e hábitos de vidas das pessoas com a infecção pelo coronavírus, e comparar os dados entre dois momentos específicos de circulação de variantes do vírus coronavírus diferentes – a Delta e a Ômicron. Os dados apresentados nessa pesquisa são o resultado de 496 entrevistas realizadas em um laboratório de análises clínicas durante o momento de realização do exame para teste para COVID-19. Ao todo foram 218 participantes de pesquisa que testaram positivos para o COVID-19 e 278 negativos. Os resultados apresentaram que a contaminação pelo coronavírus é multifatorial e dependente de muitas condições. Essa característica ainda se acentua quando os cenários de duas circulações de variantes distintas são comparados, como apresentado no estudo.

Introduction Despite the results of epidemiological and psychometric studies reporting comparable levels of tobacco dependence among males and females, some clinical studies have detected disparities. Some smoking cessation studies based on clinical setting programs reported poorer outcomes among women than men.Methods This retrospective cohort study aimed to compare treatment success and retention between men and women on a smoking cessation program (n = 1,014) delivered at a CAPS-AD unit in Brazil. The psychological intervention lasted 6 weeks for each group of 15 patients. Each patient had to participate in weekly group cognitive-behavioral therapy (CBT) sessions and individual medical appointments during this period. These appointments were focused on the possibility of prescribing pharmacological treatment (i.e., nicotine replacement therapy, bupropion, or nortriptyline) as adjuvants to group therapy.Results The women had lower smoking severity at baseline, more clinical symptoms, and lower prevalence of alcohol and drug use disorders and were older than the men. Females had significantly higher levels of success (36.6% vs. 29.7%) and retention (51.6% vs. 41.4%) than males. Sensitivity analysis showed that female gender was significantly associated with both retention and success, among those without drug use disorders only.Conclusion Depending on the smoking cessation setting (i.e., low and middle-income countries and mental health and addiction care units), females can achieve similar and even higher quit rates than males. Previous drug use disorder was an important confounding variable in the gender outcomes analyses. Future studies should try to replicate these positive smoking cessation effects of CBT-based group therapy plus pharmacotherapy in women.

ABSTRACT Introduction: Few studies have analyzed the association between physical activity and hospitalizations or mortality as a result of the new coronavirus, particularly in Brazil. Objective: To analyze the association between physical activity and deaths by Covid-19 in the Brazilian capitals. Method: An observational cross-sectional ecological study, in which data on the prevalence of physical activity during leisure time, and deaths by Covid-19 were analyzed for twenty-six Brazilian capitals plus the Federal District. Data were collected through the Risk Factor Surveillance System for chronic non-communicable diseases, and SUS Analytical for COVID-19 in Brazil, of the Brazilian Ministry of Health. For the data analysis, simple Pearson correlation and multiple regression were used, with a level of significance of 5%. Results: The data show the existence of an inverse correlation between physical activity during leisure time and accumulated deaths (r = −0.44, p = 0.03), mortality rate/100,000 inhabitants (r = −0.43, p = 0.02), and the lethality of the disease (r = −0.51, p = 0.01). They also show an inverse association between physical activity during leisure time and accumulated deaths (β = −485.1, p = 0.04), as well as with the lethality of the disease (β = −0.21, p = 0.02), even after adjusting for confounding variables. Conclusion: The inverse association observed between physical activity, accumulated deaths, and lethality of Covid-19 can bring important reflections on the actions that have been implemented by government agencies, at both state and municipal levels, in relation to the practice of physical activity by the population. Level of evidence III; Cross-sectional ecological study.

Bio-filler from eggshells as reinforcement of bio-based polymers are based on their benefits as adequate strength and stiffness, besides friendly, degradable and renewable environment. Eggshell is an agricultural waste considered as garbage, contributing to pollution; nevertheless, it can be transformed into bio-calcium carbonate, acquiring new values. As biodegradable polymers, there were chosen PLA (poly-lactic-acid) and PBAT (butylene adipate co-terephthalate), thermoplastics capable to be processed via conventional methods. PLA is a linear, aliphatic thermoplastic polyester, high in strength and modulus, but brittle. PBAT is a synthetic polymer, very flexible, based on fossil resources with high elongation at break, but low strength. It will be required the use of compatibilizers, for reducing interfacial tension exhibited by PLA/PBAT immiscible blend, considering their extreme glass transition temperatures: 62 o C for PLA and – 30 o C for PBAT. Herein it was used ionizing radiation for inducing compatibilization by free radicals, improving dispersion and adhesion of blend phases, without using chemical additives, at room temperature. PLA, acting as compatibilizer, was previously e-beam and gamma radiated, at 150 kGy. PBAT/PLA 50/50 blend with 15 phr of bio-filler from avian eggs 125 µm particle size and both compatibilizers were homogeneized in a co-rotating twin-screw extruder, within a temperature profile 120 to 145 o C, from hopper to die. Characterization involved: Differential Scanning Calorimeter, Thermogravimetric Analyses, Fourier Transform Infrared Spectroscopy, Wide Angle X-Ray Diffraction, Tensile Strength and Elongation at Break.

PURPOSE: Comparison of body composition and physical activity level according to self-perception health in schoolchildren. The balance between health and well-being in children and adolescents can be understood through the physical, social, mental and spiritual environment. METHODS: The sample consisted of 90 schoolchildren, 40 boys and 50 girls aged 9 to 11 years old, who are part of the Ilhabela Mixed-Longitudinal Growth, Development and Physical Fitness Project coordinated by Center of studies physical fitness research laboratory from São Caetano do Sul (CELAFISCS) in São Paulo. Body composition measurements were analyzed according to the CELAFISCS standard, physical activity level and sedentary time objectively determined by accelerometer (actiGraph GT3X analyzed with Freedson 1998). For the perception of health, the Likert scale Diet and Lifestyle questionnaire was used. STATISTICAL ANALYSIS: ANOVA One Way, Post-hoc Bonferroni, the significance level adopted was p <0.05. RESULTS: There were significant differences in body composition in body weight, BMI, waist circumference and X3DC according to self-perception health. This phenomenon was not found in regards to physical activity and sedentary behavior. CONCLUSION: According to students self-perception health, differences in body composition were found when compared to self-rated health, and body composition values were lower in students who reported a positive score.

ABSTRACT Introduction: Due to the relationship between early identification of physical and anthropometric characteristics above the population mean in children and adolescents, and success in sports, detecting potential sports talents should be broadly and systematically used as a strategy for the early identification of physical characteristics favorable to the sport in question. However, most studies do not use representative samples, or else they present talent detection without using valid scientific methods. This retrospective, comparative study therefore presents the identification of potential sports talents using the Z Strategy, calculated with anthropometric, neuromotor and physical fitness data. Objective: To identify physical abilities and anthropometric values above what are considered the normal ranges in a population of students in the 8th year of basic education, in Chile. Methods: The sample consisted of 9,429 students from public and private schools (50.9% boys). Data were obtained from a cross-sectional study conducted in 2013. Physical fitness and anthropometric data were recompiled through the Educational Quality Measurement System (Sistema de Medición de la Calidad de Educación – SIMCE) of physical education. The “Z Strategy” was used to detect sports talents by identifying values above the population mean. Results: In at least one variable, a total of 619 male and 623 female students with a standard deviation ≥2 (Z2) were detected. Conclusion: “Z Strategy” was able to detect sports talents of both sexes and of different ages. Level of evidence III; Retrospective comparative study.

OBJECTIVE: to associate sitting time with body composition, muscle strength and quality of life in health professionals. Methods: The sample consisted of 1036 professionals (241 male and 794 female). Sedentary behavior was measured in minutes / day during the week (short IPAQ). Measures included BMI (kg / m2), abdominal circumference (cm), and handgrip (kg). Quality of life was divided into physical, psychological, social, environmental and general domains (WHOQOL-BREF ). STATISTICAL ANALYSIS: Multiple linear regression was used to associate the study variables. RESULTS: Factors associated with sitting time comprised: age and the physical, psychological and social domains of quality of life. The percentage of fat, BMI, Abdomen circumference (cm), Muscular strength (kg) and the environmental and general domains were not associated with sitting time as it is shown in the table below. CONCLUSION: In the present sample sitting time during a weekday presented an inverse association with age and the physical, psychological and social domains of quality of life.Table: No title available.