- Conference Article
- 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a4704
Effects of an Interdisciplinary Clinical Care Pathway on Mortality With Patients Admitted for Pneumonia
- Apr 30, 2024
- R Mansukhani + 17 more +17
Publications from 2021 to 2026
Showing 10 of 33 papers
Effects of an Interdisciplinary Clinical Care Pathway on Mortality With Patients Admitted for Pneumonia
My patient has a neurogenic bladder
Treatment of bladder dysfunction involves both your patient and their caregivers. The goal of treatment is to preserve renal function and to maintain continence.
Read moreHirschsprung disease
Linda Demarest is a wound care nurse from Pompton Plains, N.J. The author has disclosed no financial relationships related to this article.
Read morePredation and parasitism of naturally occurring and sentinel stink bug egg masses of<i>Halyomorpha halys</i>(Stål) and<i>Nezara viridula</i>(L.) (Hemiptera: Pentatomidae) in various southeastern habitats
Stink bugs, including Halyomorpha halys (Stål) and Nezara viridula (L.), are agricultural pests that feed on fruit in a variety of crops. Monitoring predation and parasitism of stink bug egg masses furthers our understanding of potential biological control tactics. However, best practices for laboratory and field assessments of parasitism and predation of egg masses require further attention. We carried out a series of laboratory and field experiments to test whether parasitism and predation for three types of sentinel H. halys egg masses, fresh, frozen, and refrigerated, varied in agricultural commodities. In addition, we asked if predation and parasitism differed between sentinel and naturally occurring H. halys and N. viridula egg masses in soybean. In the laboratory, more H. halys eggs were parasitized by Trissolcus euschisti (Ashmead) (Hymenoptera: Scelionidae) if they were frozen or refrigerated compared to fresh eggs. Similarly, in the field, parasitism was higher for frozen egg masses than fresh. In 2018 and 2019, H. halys natural egg masses had higher parasitism and lower predation compared to sentinel egg masses in soybean. In a paired field test during 2020 and 2021, there was no difference in parasitism between H. halys natural and sentinel eggs, but much higher incidence of parasitism was detected in natural N. viridula egg masses than sentinel eggs. Collecting natural egg masses is the best methodology for field assessment of parasitism of stink bug egg masses; however, if natural egg masses are not easily available, deploying refrigerated sentinel egg masses is a good alternative.
Read moreSocio-Ecologic Perspective: Barriers Complicating Post-Intensive Care Syndrome Mitigation
Objective:Post-intensive care syndrome (PICS) is a phenomenon whereby survivors of an intensive care unit (ICU) admission subsequently experience issues with physical, cognitive, or mental health status persisting beyond the acute hospitalization. Risk factors for developing PICS include prolonged mechanical ventilation with sedation and immobility. PICS is a devastating illness that negatively alters the life path of many individuals with tremendous economic impact. Methods: This qualitative study employed a grounded theory approach to understand the systemic barriers blocking mitigation and treatment of PICS in all seven ICUs across Essex County, New Jersey (NJ) through semi-scripted interviews conducted with 11 members of the healthcare teams with at least one from each site. Thematic analysis was performed with open, axial, and selective coding. Results: Applying socio-ecologic viewpoint to data illustrate significant barriers on both an interpersonal and organizational level that decrease the operationalization of PICS mitigation measures as identified by healthcare providers. Of those interviewed, eight (73%) were physicians and the remaining were nurses. Significant thematic issues included understanding the risk factors of PICS but feeling powerless to institute mitigation efforts; experiencing lack of enthusiasm due to the absence of institutionalized mitigation protocols; noting frustration about closing the gap between academic recommendations and the ability to operationalize these appropriately; and feeling unable to effectuate meaningful change. Conclusion: Providing education to the target population and healthcare provider stakeholders regarding the barriers against PICS mitigation can alter the status quo.
Read moreA pilot study of animal assisted activity among hospitalized older adults
Probing the relevance of MoO<sub>2</sub> nanoparticles’ synthesis on their catalytic activity by inelastic neutron scattering
Nanosized MoO2 can be prepared by different protocols, which yield different morphologies of the nanoparticles. Among their many properties, they can serve as catalysts for styrene oxidation (among other olefins), which is an industrially relevant transformation. In this work, we prepared MoO2 nanosized catalysts by two slightly different hydrothermal protocols using ethylenediamine and either Fe2O3 or hydroquinone. When used in catalysis, kinetic data evidenced that depending on the synthesis protocol of MoO2, induction periods occur (for the catalyst prepared with hydroquinone) with obvious different kinetic profiles and, in addition, product selectivity was also affected. To gain some insight on what is behind these results of the catalytic activity, a combined approach of studies has been conducted. DRIFT and inelastic neutron scattering (INS) techniques were used to assess the adsorbed species at the surface of both the fresh (DRIFT and INS) and recovered (INS) catalysts. Results from this study showed that when hydroquinone was used, an organic shell coated the MoO2 nanoparticles, which negatively influenced the catalytic performance.
Read moreDecoupling between the translation and rotation of water in the proximity of a protein molecule.
The interaction between water and biomacromolecules is of fundamental interest in biophysics, biochemistry and physical chemistry. By combining neutron scattering and molecular dynamics simulations on a perdeuterated protein at a series of hydration levels, we demonstrated that the translational motion of water is slowed down more significantly than its rotation, when water molecules approach the protein molecule. Further analysis of the simulation trajectories reveals that the observed decoupling results from the fact that the translational motion of water is more correlated over space and more retarded by the charged/polar residues and spatial confinement on the protein surface, than the rotation. Moreover, around the stable protein residues (with smaller atomic fluctuations), water exhibits more decoupled dynamics, indicating a connection between the observed translation-rotation decoupling in hydration water and the local stability of the protein molecule.
Read moreEffect of water on the electroresponsive structuring and friction in dilute and concentrated ionic liquid lubricant mixtures.
The effect of water on the electroactive structuring of a tribologically relevant ionic liquid (IL) when dispersed in a polar solvent has been investigated at a gold electrode interface using neutron reflectivity (NR). For all solutions studied, the addition of small amounts of water led to clear changes in electroactive structuring of the IL at the electrode interface, which was largely determined by the bulk IL concentration. At a dilute IL concentration, the presence of water gave rise to a swollen interfacial structuring, which exhibited a greater degree of electroresponsivity with applied potential compared to an equivalent dry solution. Conversely, for a concentrated IL solution, the presence of water led to an overall thinning of the interfacial region and a crowding-like structuring, within which the composition of the inner layer IL layers varied systematically with applied potential. Complementary nanotribotronic atomic force microscopy (AFM) measurements performed for the same IL concentration, in dry and ambient conditions, show that the presence of water reduces the lubricity of the IL boundary layers. However, consistent with the observed changes in the IL layers observed by NR, reversible and systematic control of the friction coefficient with applied potential was still achievable. Combined, these measurements provide valuable insight into the implications of water on the interfacial properties of ILs at electrified interfaces, which inevitably will determine their applicability in tribotronic and electrochemical contexts.
Read moreStress Fractures of the Ankle and Hindfoot
Stress fractures of the ankle and hindfoot are common injuries in athletes. Most of these fractures can be treated nonoperatively, but certain factors including fracture location, vascular supply, lower leg alignment, and return to play considerations may require surgical intervention. Stress fractures of the ankle and hindfoot can also be classified as low risk and high risk in regard to propensity to heal with conservative treatment. Generally, low-risk fractures include the distal tibia, distal fibula, talus, and calcaneus. High-risk fractures include the medial malleolus and navicular. The treating health-care provider should have a low index for suspicion for stress fracture and be able to identify risk factors in regard to bone health, structural alignment, and training/competing issues in order to achieve a quick recovery and minimize the chance for recurrence of injury.
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