Delaware Technical Community College

With the growing dependence on APIs in contemporary software systems, API security has become a pressing challenge, especially against automated AI-based attacks and zero-day threats. Signature-based and rule-based security solutions are not adequate to identify well-structured pattern-based sophisticated reconnaissance or probing attacks. This study suggests an AI-based Security Platform (ASP) that learns dynamic patterns of valid API requests from actual application traffic. The system uses hierarchical semantic analysis to vectorize and flatten structured API payloads and then extract features. A self-attention mechanism augmented Recurrent Neural Network (RNN) captures the structural and temporal patterns in the request sequences. Anomaly detection policy classifies traffic in real time and only permits behavior conforming to the learned patterns while rate-limiting or blocking exploratory calls deemed anomalous. This strategy avoids attackers mapping system behavior and lowers the attack surface, with an added benefit of zero-day resilience. The new method makes large gains in accuracy and false-positive rate over current models.

Background:High frequency jet ventilation (HFJV), conventional ventilation (CV), and inhaled nitric oxide (INO) are therapies that are often used simultaneously. In our Level IV NICU, we noticed a discrepancy between CV set PEEP (actual PEEP), Pmin, and measured PEEP on HFJV when CV modes were changed. We aimed to evaluate the effect of this discrepancy on the delivery of INO. Methods:A Drager Babylog equipped with a F&P Evaqua 2 circuit interfaced a Bunnell LifePulse HFJV, INO was placed in-line (between gas outlet and heater) on the HFJV from a Mallinckrodt INOmax DSIR system to a Drager neonate test lung. Two models were evaluated, Model 1 included CV-PC CMV, PIP 25, Ti 0.35, RR 5, PEEP 6, HFJV- PIP 30, RR 420, Ti 0.02 and INO at 20 ppm (sampling post ETT and within the test lung). Model 2 included CV- SPN CPAP, PEEP 6, PS 6, with the HFJV and INO unchanged. Variables for analysis included: CV measured PEEP/Pmin, HFJV measured PEEP/ΔP and INO sampling on DSIR. Due to an observed decrease in PEEP and increase in ΔP on the HFJV when switching between models slightly larger VTs would be expected. INO sampling was obtained from within the test lung to evaluate INO delivery and values were obtained three times in each model after stabilization and averaged. Student’s t-test was used to determine statistical significance. Results:Average values in CMV PC mode were CV PEEP 6.2, Pmin 5.9, HFJV PEEP 6.1, HFJV ΔP 23.9, INO 19 ppm. Average values in SPN CPAP mode were CV PEEP 5.8, Pmin 5.2, HFJV PEEP 5.3, HFJV ΔP 24.7, INO 19 ppm. Pmin/HFJV PEEP is decreased and HFJV ΔP is increased when CV mode is changed from CMV PC to SPN CPAP. As PEEP decreases and ΔP increases, larger VTs are expected. All reported pressure fluctuations were determined not significant (Table 1) and fall within manufacturer's specifications. INO delivery was not affected when CV mode changes were made when used in conjunction with HFJV. Conclusions:Despite variability in CV Set PEEP, Pmin, and measured PEEP between CV and HFJV, when CV modes were changed INO delivery remained stable in our bench model. Further research must be done to evaluate expected volume increases and the potential impact to neonatal patients on these therapies.Measured Values from Bench AnalysisMode of CVCV PEEPCV PEEP AveragePminPmin AverageHFJV PEEPHFJV PEEP AverageHFJV ΔPHFJV ΔP AverageAverage iNO Measured in Test Lung (ppm)CMV PC6.0/6.4/6.16.25.9/5.9/5.85.96.1/6.0/6.16.123.9/24.1/23.723.919SPN CPAP5.7/5.8/5.85.85.4/5.2/5.15.25.4/5.2/5.25.324.6/24.6/24.924.719.7  p>0.05 p>0.05 p>0.05 p>0.05p>0.05Table 1 shows the average measured values over three trials in two bench models.

Continuous flow microreactors operating at short residence times and high temperatures can give high HMF productivity and contribute to process intensification of biorefineries.

This community-based participatory action research (CBPAR) study describes a method for evaluating an after-school resilience-focused intervention in a low-resource rural area of southern India. Communities Rising, a locally developed resilience and academic program, was evaluated in a cross-continent collaboration between a research team at a U.S. university and the local community. The CBPAR literature highlights the importance of cultural considerations, community considerations, and community participation in the research process. The present case study describes the CBPAR research process and considerations at every phase of the research project, providing a road map of how community engagement can strengthen research, empower the community, and provide valuable knowledge. This study was conducted in three phases that focused on inclusion of local voices in the development both of the resilience program and the evaluation data collection process. Youth surveyors were particularly key to the research process. Data on participant demographics, satisfaction with the program, and qualitative contributions are also provided. Strengths and limitations of this study process in a rural community are discussed.

The discovery of rapid eye movement (REM) sleep and, in particular, REM sleep behavior disorder (RBD) have brought elusive nightmarish experiences to scientific scrutiny. This article summarizes a century of sleep research to examine the maladies of dreaming, their pathophysiologic significance, and management. Under healthy physiologic conditions, REM sleep is characterized by vivid mentation combined with skeletal muscle paralysis. The loss of REM sleep atonia in RBD results in vivid, potentially injurious dream enactment to patients and bed partners. RBD is common, affecting at least 1% of the population and is primarily caused by α-synuclein pathology of REM sleep-related brainstem neurons. The majority of patients with RBD ultimately develop a neurodegenerative syndrome such as Parkinson disease, dementia with Lewy bodies, or multiple system atrophy. Among patients with Parkinson disease, RBD predicts an aggressive disease course with rapid cognitive, motor, and autonomic decline. RBD is diagnosed by the presence of dream enactment episodes (either recorded or clinically recalled) and physiologic evidence of REM sleep without atonia demonstrated on polysomnography. Bedroom safety is of paramount importance in the management of RBD while pharmacokinetic options include melatonin or clonazepam. The injurious dream enactment of RBD is common and treatable. It is a syndrome of α-synuclein pathology with most patients ultimately developing Parkinson disease, dementia with Lewy bodies, or a related disorder.

"This book explores current cultural norms and their influence on curriculum and educational environments and intends to improve the understanding of social change and social responsibility at different sociological levels within various fields pertaining to higher education"--

Ancient DNA (aDNA) and standard osteological analyses applied to 11 skeletons at a late 17th to early 18th century farmstead site in Delaware to investigate the biological and social factors of settlement and slavery in colonial America. Osteological analysis and mitochondrial DNA (mtDNA) sequencing were conducted for all individuals and the resulting data contextualized with archaeological and documentary evidence. Individuals of European and African descent were spatially separated in this colonial cemetery. The skeletal remains exhibited differences in osteological features and maternal genetic ancestry. A specific mtDNA haplotype appeared in a subset of the European-descended individuals suggesting they were maternally related. Individuals of African descent were not maternally related, and instead showed a diversity of haplotypes affiliated with present-day Western, Central, and Eastern regions of Africa. Along with the bioarchaeological and documentary evidence, the aDNA findings contribute to our understanding of life on the colonial Delaware frontier. Evidence of maternal relatedness among European-descended individuals at the site demonstrates kin-based settlements in 17th century Delaware and provides preliminary identifications of individuals. The maternal genetic diversity of the individuals with African descent aligns with the routes of the trans-Atlantic slave trade but broadens our understanding of the ancestries of persons involved in it. Burial positioning, osteological pathology, and lack of maternal kinship among individuals of African descent provide tangible evidence for the emergence of racialized labor and society in Delaware during the late 17th century.