Ginger (France)

1 - IntroductionLe Quaternaire des Pays de Savoie est caractérisé par un impact majeur de l’action des glaciers et des évènements « tardiglaciaires ». Cette journée se déroule dans l’avant pays savoyard et plus généralement dans la province du Bugey. Un premier arrêt à l’église de Saint Alban de Montbel (arrêt A, fig. 1) permet un vaste panorama sur le lac d’Aiguebelette et le chaînon jurassien de la Montagne de l’Epine. Le second arrêt (B, sur la figure 1) permet une vue sur la tourbière de...

La prevalencia del consumo de sustancias entre jóvenes representa un reto significativo para su desarrollo integral. Las intervenciones docentes y políticas públicas emergen como herramientas cruciales para abordar esta situación. Esta investigación buscó comprender el impacto de dichas políticas en las prácticas formativas de docentes de la Institución Educativa Juan XXIII de Medellín. Se empleó un enfoque cualitativo, basado en la praxis hermenéutica, para decodificar significados en el lenguaje y acciones de los participantes. A través de la triangulación interpretativa, se examinaron seis categorías vinculadas a políticas y proyectos educativos locales. Los hallazgos indican una "distancia hermenéutica" entre políticas formuladas y su aplicación real, atribuida a diversos factores, como la desconexión entre teoría y práctica. En conclusión, el estudio destaca la necesidad de brindar apoyo emocional y mental a los estudiantes y de proporcionar suficientes recursos y apoyo para la aplicación efectiva de las políticas públicas.

This supporting document provides the measured and inversed profiles (Figure S1-S24) for the data set from Geay et al. ( 2020) and which is used in section 4.2 of the manuscript.Figure S25 presentes a river slope-based empirical equation to predict the attenuation coefficient of rives.

The aim of this preliminary study was to obtain a proteomic overview of our previously reported TAM1 asymptomatic family carrying the mutation c.216C>G; p.His72Gln in the EF-hand domain of STIM1.

We measured eicosatrienoic acids in 21 normotensive subjects classified as salt-resistant (SR=13) or salt-sensitive (SS=8) with the rapid protocol of Indiana University (high salt, HS=460 mEq Na/24 hrs, low-salt, LS=10 mEq Na/24 hrs + furosemide 40 mg x 3). No EETs were detected in urine; hence, ELISA 14-15 DHETs were taken to represent the total pool of this urine isoform (U-TP). Plasma total pools (8-9,11-12,14-15 and 14-15 P-TP) are the sum of EETs+DHETs (HPLC-MS), and their results were similar, so the former are reported. Analyses required log-transformation of not normally distributed data. U-TP was not changed by HS but decreased with LS (Δlog -0.47±0.19, p<0.01), consistent with the response of a natriuretic system. Further, in the baseline, HS and LS periods combined, U-TP correlated positively with UNaV (r=0.35, p<0.005), fractional excretion of Na (r=0.37, p<0.003) and Na/K ratio (r=0.39, p<0.002), indicating inhibition of ENaC. P-TP was not changed by HS (due to inhibited soluble epoxide hydrolase with reduction in DHETs and increase in EETs) but was increased by LS (Δlog 0.05±0.02, p<0.01), including EETs (0.04±0.02, p<0.03), inconsistent with a natriuretic system. P-TP did not correlate with urine parameters. Instead, plasma DHETs correlated with aldosterone (r=0.34, p<0.005) and plasma EETs with catecholamines (r=0.45, p<0.001). Differences between SR and SS subjects included: a) lower levels of U-TP and P-TP in SS than SR, significant in some stages of the experiment, b) lack of response of U-TP to changes in salt balance in SS, c) lack of the correlations between U-TP and natriuresis/ENaC activity and between DHET/aldosterone in SS, all observed only in SR. We conclude that: 1. Urine eicosatrienoic acids reflect a renal pool involved in regulation of natriuresis whereas plasma ones are probably of systemic origin and uninvolved in Na excretion, 2. There may be a feed-forward mechanism for the systemic, non-renal effects of aldosterone, by stimulation of inactive DHETs, 3. Catecholamines may stimulate epoxygenases or EETs may produce neuronal release of catecholamines, which remains to be investigated, and 4. Differences between SS and SR suggest abnormalities of eicosatrienoic acid regulation of natriuresis in SS subjects.

The effects of heavy-ion test conditions and beam energy on device response are investigated. These effects are illustrated with two types of test vehicles: SRAMs and power MOSFETs. In addition, GEANT4 simulations have also been performed to better understand the results. Testing to high fluence levels is required to detect rare events. This increases the probability of nuclear interactions. This is typically the case for power MOSFETs, which are tested at high fluences for single event burnout or gate rupture detection, and for single-event-upset (SEU) measurement in SRAMs below the direct ionization threshold. Differences between various test conditions (e.g., “in air” or vacuum irradiations, with or without degraders) are also explored. Nuclear interactions with any materials in the beam's path can increase the number of high collected charge events potentially impacting the experimental results. A “species” effect has been observed in the power MOSFET devices examined in this work. When the beam energy increases, the single-event-burnout (SEB) voltage is constant, such that the SEB voltage is determined only by the species of the ion beam. The species effect is shown to be due to high collected charge events induced by nuclear interactions, which can lead to premature SEB. If a device is sensitive to the species effect, the worst-case test conditions will be for the heaviest ion species, which can produce the largest linear-energy-transfer (LET) secondaries. SRAMs can also be sensitive to the species effect below the direct ionization threshold LET. For the devices used in this work, the worst-case energy for SEU characterization is <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$\sim 10'{\rm s}~{\rm MeV/u}$</tex> </formula> where the species dominates the device response. In the 10's MeV/u range the heaviest species result in the largest cross sections. However, at very high energies (100's MeV/u), the species is not the dominant parameter because of differences in the population of secondaries created by nuclear interactions. At very high energies the SEU cross section below the direct ionization threshold LET decreases by several orders of magnitude compared to 10's MeV/u SEU data. The results of this work emphasize that there is no such thing as an “ideal” test facility. Nevertheless, these results can be used by experimenters to optimize the integrity of their results for given test conditions.

The generation of optically carried microwave signals is of great interest for a wide range of fields, from long-range transmission of RF to wideband radar signal processing. Among the available generation techniques, the potentialities of optical heterodyning are firmly established. However, it leads to severe constraints in optical phase-locked loop (OPLL) design. In this paper, we report on the realization of a compact and ruggedized Er,Yb:glass DFL at 1.5 μm stabilized with three servo-loops.

In this paper, we describe GREENET (an early stage training network in enabling technologies for green radio), which is a new project recently funded by the European Commission under the auspices of the 2010 Marie Curie People Programme. Through the recruitment and personalized training of 17 Early Stage Researchers (ESRs), in GREENET we are committed to the development of new disruptive technologies to address all aspects of energy efficiency in wireless networks, from the user devices to the core network infrastructure, along with the ways the devices and equipment interact with one another. Novel techniques at the physical, link, and network layers to reduce the energy consumption and carbon footprint of 4G devices will be investigated, such as Spatial Modulation (SM) for Multiple-Input-Multiple-Output (MIMO) systems, Cooperative Automatic Repeat reQuest (C-ARQ) protocols, and Network Coding (NC) for lossy networks. Furthermore, cooperation and cognition paradigms will be exploited as additional assets to improve the energy efficiency of wireless networks with the challenging but indispensable constraint of optimizing the system capacity without degrading the user's Quality-of-Service (QoS).

PurposeThe purpose of this paper is to conduct a comparative study of the surface modifications induced by two different lasers on a 2050‐T8 aluminum alloy, with a specific consideration of residual stress and work‐hardening levels.Design/methodology/approachTwo lasers have been used for Laser shock peening (LSP) treatment in water‐confined regime: a Continuum Powerlite Plus laser, operating at 0.532 mm with 9 ns laser pulses, and near 1.5mm spot diameters; a new generation Gaia‐R Thales laser delivering 10 J‐10 ns impacts, with 4‐6mm homogeneous laser spots at 1.06 mm. Surface deformation, work‐hardening levels and residual stresses were analyzed for both LSP conditions. Residual stresses were compared with numerical simulations using a 3D finite element (FE) model, starting with the validation of surface deformations induced by a single laser impact.FindingsSimilar surface deformations and work‐hardening levels, but relatively lower residual stresses were obtained with the new large 4‐6 mm impact configuration. This was attributed to a reduced number of local cyclic loadings (2) compared with the small impact configuration (4). Additionally, more anisotropic stresses were obtained with small impacts. FE simulations using Johnson‐Cook's material' behavior were shown to simulate accurately surface deformations, but to overestimate maximum stress levels.Research limitations/implicationsThis work should provide LSP workers a better understanding of the possible benefits from the different LSP configurations currently co‐existing: using small (&lt;2 mm) impacts at high‐cadency rates or large ones (&gt;4‐5 mm). Moreover, experimental results and simulated data had never been presented on 2050‐T8 Al alloy.Originality/valueAn experimental (and numerical) comparison using two distinct laser sources for LSP, has never been presented before. This preliminary work should help LSP workers to choose adequate sources.