Greo

ABSTRACTAs essential pollinators to native plant species, Bombus (Latreille) are integral components of terrestrial ecosystems. Canada is home to approximately 41 native bumblebee species, 24.4% of which are threatened with extinction globally. In cases of extreme population decline, ex situ conservation, including conservation breeding and reintroduction, has been recommended and is being implemented to assist in species recovery. To date, Bombus breeding efforts have low mating success. Adapting assisted reproduction techniques from apiculture could increase mating success in captive breeding programmes and support controlled breeding to enhance genetic diversity. To this end, we investigated a new dissection technique for male Bombus species, in which reproductive organs are removed from the abdomen through the cloaca. We found that the pull dissection methodology was more effective at reliable sample collection than dissections performed via the classic methodology (probability of finding sperm in accessory ducts for the classic method = 2.5%, [CI = 0.23%, 14%]; probability of finding sperm in accessory ducts for the pull method = 58%, [CI = 43%, 73%]). By circumventing the need to manipulate the digestive system, this method simplifies the dissection process, increasing the chances of success for novices.

The prevalence of cannabis use continues to increase among certain populations in Canada. This study focussed on the increase in cannabis-attributable hospitalizations and emergency department (ED) visits from 2007 to 2020. To estimate the counts of hospitalizations and ED visits attributable to cannabis use, we acquired record-level hospital discharge data with ICD-10 diagnostic information for all fiscal years 2006/07 to 2020/21. Diagnostic information was used to associate each record to a health condition category for eight substances, including cannabis. The prevalence of cannabis use was estimated for each province or territory, calendar year, sex and age using national survey information. These estimates were used to adjust relative risk estimates derived from cannabis literature to calculate cannabisattributable fractions, which were in turn used to estimate the proportion of hospitalizations and ED visits that were attributable to cannabis use. Between 2007 and 2020, the overall rate of cannabis-attributable inpatient hospitalizations increased by 120%, from 6.4 in 2007 to 14.0 per 100 000 in 2020. Cannabis-attributable ED visits increased by 113%, from 52.1 per 100 000 in 2007 to 111.0 per 100 000 in 2019, and then decreased by 12% in 2020. This study found that the increases in hospitalizations and ED visits were partly attributed to neuropsychiatric conditions, particularly hospitalizations due to psychotic disorders and ED visits due to acute intoxication among children and youth. Ongoing monitoring of cannabis-attributable harms is necessary to understand the harms related to use and the factors that influence the ways in which people use cannabis and seek care. Further research may distinguish the early effects of legalization trends from the early pandemic period data.

Effective and comprehensive harm reduction strategies to mitigate gambling-related harms are needed worldwide. The development of such strategies is however resource intensive. Using existing models in multiple contexts would thus be advisable. This study is part of a larger project investigating the feasibility and acceptability of the Canadian Lower Risk Gambling Guidelines (LRGG) within a Finnish cultural context. The Canadian guidelines recommend not gambling more than 1% of one’s household income, not gambling more than 4 days per month, and to avoid regularly gambling at more than 2 types of gambling products.13 Focus group interviews were conducted (N = 37, 23 women, 14 men) across five subpopulations: individuals gambling at no-risk/low-risk levels, individuals with past experiences of problematic gambling, concerned significant others of those with gambling problems, professional gamblers, and social workers and health care professionals. The analysis utilised a deductive approach.While the subpopulations differed in their assessment of the LRGG in some regards, we were able to synthesise three concrete suggestions to adjust the Canadian LRGGs into the Finnish context. Participants proposed rephrasing the guidelines as follows: (1) Limit gambling to a fixed percentage of monthly personal income after taxes and other fixed expenses, (2) Restrict the number and duration of weekly gambling sessions, (3) Avoid regular participation in the most harmful forms of gambling, such as online casino games.Overall, the LRGG were considered as useful also in the Finnish context. However, our results suggest that some culturally specific rewording may be advisable. The main challenge in the implementation of the LRGG is that respondents across groups considered the guidelines to be aimed at someone else. Implementation therefore requires clear communication that these guidelines are for all individuals who gamble, not only those experiencing problems.

The rapid development and adoption of oral anticancer agents (OAAs) for cancer management have shifted patients' roles from recipient to owner of their care delivery, assuming their responsibilities for self-managing their OAA treatments at home, while the concept of oral anticancer agent self-management (OAA-SM) has not been well clarified and defined. This study was to clarify the concept of OAA-SM and identify major components, influential factors, and consequences of OAA-SM, as well as propose a representative conceptual model of OAA-SM. A literature review was conducted concerning the concept and application of OAA-SM. The Walker and Avant method for concept analysis was utilized to guide the examination of OAA-SM. OAA-SM is a multifaceted and dynamic process that requires continuous adaptation by patients as multiple self-management challenges can emerge throughout OAA treatments. The defining attributes of OAA-SM include OAA adherence, adverse-effect self-management, patient-provider communication, and OAA safe storage, handling, and administration practices. Oral anticancer agent-SM is potentially influenced by a variety of patient-related, OAA-related, and healthcare system factors. Effective OAA-SM is associated with better patient and healthcare outcomes. The clarification of the concept of OAA-SM and the identification of attributes of OAA-SM and their interrelationships contribute to the body of knowledge in OAA-SM. This concept analysis provides the foundation to increase healthcare providers' understanding of patients' needs for OAA-SM support and guides the development of patient-centered interventions to empower and engage patients and their families in effective OAA-SM, and improve patients' quality of life and care.

Gambling is a popular activity among older adults that has potential for growth as the population ages. Benefits have been identified for recreational gamblers (those experiencing no gambling-related problems), but there are many social, financial, and health harms affecting quality of life related to gambling across the spectrum of risk levels. Because of their greater numbers, low and moderate risk (LMR) older adult gamblers are responsible for higher levels of population harm. Therefore, this study examines outcomes experienced by older adults who participate in gambling at recreational and LMR levels to better understand protective factors that contribute to quality of life. Guided by activity theory and a modified self-complexity model, we explore how leisure complexity and employment buffer the relationship between gambler type and factors associated with well-being, namely social support (both perceived and received) and stress. A sub-sample of 3232 adults, age 55 years and older, who gambled in the past year was drawn from the 2013–2014 Canadian Community Health Survey. Data were analyzed using linear regression with moderation, focusing on the interactions of gambling risk level with leisure complexity and employment. Recreational gamblers reported greater role complexity and more diverse leisure lifestyles, both of which were associated with greater social support and reduced stress. Life stress was higher among older adults who worked for pay. Even so, having a job appeared to temper stress levels among LMR gamblers, suggesting the importance of maintaining a diversity of social roles and leisure activities, where possible, to enhance quality of life.

Mental health professionals such as psychiatrists and psychotherapists assess their patients by identifying disorders that explain their symptoms. This assessment requires an inference to the best explanation that compares different disorders with respect to how well they explain the available evidence. Such comparisons are captured by the theory of explanatory coherence that states 7 principles for evaluating competing hypotheses in the light of evidence. The computational model ECHO shows how explanatory coherence can be efficiently computed. We show the applicability of explanatory coherence to mental health assessment by modelling a case of psychiatric interviewing and a case of psychotherapeutic evaluation. We argue that this approach is more plausible than Bayesian inference and hermeneutic interpretation.

How do self-regulated health professions' regulatory bodies address financial conflict of interest (coi) and ensure accountability to the public? using document analysis, we examined how four ontario regulatory colleges (physicians, nurses, physiotherapists, audiologists/speech-language pathologists) defined coi and the education, guidance and enforcement they provided for coi-related issues. These colleges are upholding the mandates to define, identify and address financial coi by providing regulations or standards and guidelines to their membership; they differed in the amount of educational materials provided to their registrants and in the possible coi scenarios they presented. Although there were few disciplinary hearings pertaining to financial coi, findings for the hearings that did occur were documented and posted on the college public registers (the listing of all registered college members along with all relevant practice information), informing the public of any limitations or restrictions placed on a member as a result of the hearing.

New technology is changing the nature of gambling with interactive modes of gambling becoming putatively associated with higher rates of problem gambling. This paper presents the first nationally representative data on the prevalence and correlates of problem gambling among Australian adults since 1999 and focuses on the impact of interactive gambling. A telephone survey of 15,006 adults was conducted. Of these, 2,010 gamblers (all interactive gamblers and a randomly selected subsample of those reporting land-based gambling in the past 12 months) also completed more detailed measures of problem gambling, substance use, psychological distress, and help-seeking. Problem gambling rates among interactive gamblers were 3 times higher than for noninteractive gamblers. However, problem and moderate risk gamblers were most likely to attribute problems to electronic gaming machines and land-based gambling, suggesting that although interactive forms of gambling are associated with substantial problems, interactive gamblers experience significant harms from land-based gambling. The findings demonstrate that problem gambling remains a significant public health issue that is changing in response to new technologies, and it is important to develop strategies that minimize harms among interactive gamblers.