Ignatius Hospital

The paper considered a moving mesh finite element method (MMFEM) in solving malaria transmission model that incorporates control strategies. The SEIR-styled reaction-diffusion governing PDE equations were cast into weak formulations to track the features of interest, specifically the disease dynamics. The numerical method involves discretising the spatial domain into finite elements (FEM) guided by appropriate basis function and time discretisation using the implicit (backward Euler) method which ensures unconditionally stable requirements and achieved through the geometric conservation approach via a suitable monitor function (M) and equidistributed so that the integral between M consecutive nodes are equal. The theoretical model was numerically validated to confirm the practical utility of the MMFEM numerical scheme under varying epidemiological scenarios. The validation confirms that the MMFEM approach provides a reliable, accurate, and stable framework for modelling vector-borne disease dynamics. A further research could explore the utility of the Physics Informed Neural Networks (PINNs) technique in solving the reaction-diffusion malaria transmission model which was not considered in this study.

Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa kelas III-C SD St.Ignatius Medan menggunakan model pembelajaran kooperatif tipe Number Heads Together(NHT) pada mata pelajaran matematika materi perkalian dan pembagian. Metode dalam penelitian ini adalah Penelitian Tindakan Kelas (PTK) melalui penggunaan model pembelajaran kooperatif tipe Number Heads Together(NHT) menggunakan model Kemmis dan Taggart yang dilakukan dalam dua siklus. Subjek penelitian adalah siswa kelas III-C SD St.Ignatius Medan yang berjumlah 25 siswa terdiri dari 15 orang perempuan dan 10 orang laki-laki. Teknik pengumpulan data menggunakan tes dan observasi. Hasil penelitian menunjukkan peningkatan di setiap siklusnya. Hal ini terlihat dari hasil tes pra siklus memperoleh rata-rata sebesar 68,00 dengan ketuntasan belajar 36%. Pada siklus I memperoleh rata-rata sebesar 73,20 dengan ketuntasan belajar 60% dan di siklus II memperoleh rata-rata 83,20 dengan ketuntasan belajar 84%.

The Heythrop JournalVolume 48, Issue 3 p. 497-499 What is Systematic Theology? By Robert M. Doran Michael McGuckian, Michael McGuckian St Ignatius, GalwaySearch for more papers by this author Michael McGuckian, Michael McGuckian St Ignatius, GalwaySearch for more papers by this author First published: 04 May 2007 https://doi.org/10.1111/j.1468-2265.2007.00325_24.xRead the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume48, Issue3May 2007Pages 497-499 RelatedInformation

Factor H, a 150-kD protein, is an important down-regulating protein of the alternative pathway of the complement system. Presently, only 15 persons, representing seven families, have been described with homozygous factor H deficiency. Deficiency of this protein, inherited as an autosomal recessive trait and resulting in uncontrolled breakdown of C3, results in depletion of components of the alternative pathway (factor B, properdin) and of the terminal pathway (C5), and is associated with the onset of bacterial infections, glomerulonephritis and systemic lupus erythematosus (SLE). The proband of the family in this study suffered from subacute cutaneous lupus erythematosus and had had meningococcal meningitis due to serogroup X. She had a complete factor H deficiency at the protein level as determined by Western blotting. Among 21 relatives of the proband studied, encompassing three generations, 10 had low factor H levels, including the two children of the proband, indicating a heterozygous factor H deficiency state. In serum samples of the proband and 11 relatives prospectively studied, a strong correlation of factor H levels with C3, C3 haemolytic activity, factor B and properdin levels (P < 0.0001) was found. Alternative pathway protein levels were significantly lower (Mann-Whitney test; Z values 3.6-2.7) in sera from the four heterozygous relatives studied than in sera from the seven non-deficient relatives. In addition, a defect of the 37/42-kD H-related protein was found in the proband and two of 21 relatives, compared with four of 40 controls. A defect of the 24/29-kD H-related protein was present in one of 21 relatives studied and in none of the 40 controls.

Cardiac surgery with cardiopulmonary bypass triggers an inflammatory response involving pro-inflammatory cytokines such as tumour necrosis factor-alpha (TNF-alpha), interleukin 6 (IL-6) and interleukin 8 (IL-8). We investigated whether different anaesthetic techniques alter the pro-inflammatory cytokine response to cardiac surgery. Thirty patients scheduled for elective coronary artery bypass grafting (CABG) surgery were randomized into three groups of 10 patients. They received either volatile inhalation induction and maintenance (Group 1) or total intravenous anaesthesia with propofol and a minimal dose sufentanil (Group 2) or a moderate dose midazolam-sufentanil (Group 3). The effect of the different anaesthetic techniques on plasma levels of TNF-alpha, IL-6 and IL-8 were examined during and after anaesthesia. Concentrations of TNF-alpha, and IL-8 were comparable in the three groups throughout all measurements. Before the start of cardiopulmonary bypass, IL-6 was significantly higher in Group 1 than in Group 2 (P = 0.009) or Group 3 (P = 0.030), but there were no differences between groups after cardiopulmonary bypass or postoperatively. In the three groups there was a positive correlation between aortic clamping time and serum concentrations of IL-6 (r = 0.54) and IL-8 (r = 0.62). Length of stay in intensive care was correlated with high levels of TNF-alpha (r = 0.78). Albeit there is difference between the volatile induction and maintenance of the anaesthesia method and the total intravenous anaesthesia technique on the pro-inflammatory cytokine response to surgical stimulation before starting of cardiopulmonary bypass, neither technique can modify the pro-inflammatory cytokine response to ischaemia-reperfusion or extracorporeal circulation.

A crossover study was performed to compare the hemodynamic effects of the iso-osmolar contrast agent iodixanol (Visipaque®) 320 mg I/ml to those of the low-osmolar iohexol (Omnipaque®) 350 mg I/ml. The main hypothesis was that iodixanol and iohexol would affect left ventricular end-diastolic pressure (LVEDP) to different degrees. In 48 patients with reduced cardiac function (mean ejection fraction 33.4%), one ventricular injection was performed with each contrast medium. Ventricular, aortic and right atrial pressures and heart rate were measured continuously. Cardiac output (using Fick's principle) and systemic vascular resistance were calculated. LVEDP increased with both agents, but significantly less after iodixanol than after iohexol (P < 0.01), also in subgroups of patients in whom baseline LVEDP was severely increased and in whom 3-vessel disease was present. Immediate changes in variables reflecting vasodilatation were similar with both agents. In conclusion, both contrast agents influenced hemodynamics during ventriculography, but iodixanol had significantly less influence on LVEDP than did iohexol. Cathet. Cardiovasc. Intervent. 50:314–321, 2000. © 2000 Wiley-Liss, Inc.