- Research Article
4
- 10.1016/j.eclinm.2025.103422
Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensus
- Aug 20, 2025
- eClinicalMedicine
- Teferi Mekonnen + 37 more +37
Publications from 2021 to 2026
Showing 10 of 23 papers
Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensus
Adult Vaccine Coadministration Is Safe, Effective, and Acceptable: Results of A Literature Review
Co-administration of vaccines consists of separate preparations of different immunogens that are administered at the same time. This practice has been common in pediatrics for many years but generally was not an issue with adult vaccination until recently. With the advent of multiple new adult respiratory vaccines that are given seasonally, co-administration has been a topic of interest. This review primarily looked at the newest vaccines (COVID-19 and RSV) in combination with the most common adult vaccine (influenza) and found that co-administration with these and other vaccines in adults is safe, effective, and acceptable. Achieving adequate vaccine coverage among adults will require a coadministration strategy similar to the approach for the pediatric population and has been shown to increase vaccine uptake overall. The World Health Organization (WHO) and the Center for Disease Control and Prevention (CDC) recognize that vaccine coadministration is a feasible approach to reduce the impact of vaccine-preventable diseases. Clinicians will have critical role to play in boosting individual and public health by offering vaccine co-administration.
Read moreProportional Contribution of the Women, Infant and Children's Special Supplemental Nutrition Program on Pregnant Women's Diet Quality
Objective: The purpose of this study was to identify the proportional contribution of the special Women’s Infant and Children Food Package V for pregnant women (WIC) supplementation on pregnant women’s diet quality. Methods: Image-based diet data collection using FoodFoto™ from 63 primigravid women with singleton pregnancies in Baltimore, Maryland receiving the special WIC Food Package V for pregnant women was converted to Healthy Eating Index - 2015 (HEI-2015) total and component diet quality scores. Descriptive statistics were used to describe the total and component HEI diet quality scores. Independent t-tests and linear regression models were used to assess the contributions that the percent of WIC food in the diet and sociodemographic and health characteristics had on the components and the overall HEI score. Results: The data showed a 1% rise in WIC approved foods in the diet was associated with a significant increase in the on the HEI-2015 score (b=0.77, t=6.35, p<0.001). Higher diet quality scores were accounted for by increased consumption of four HEI components representing healthy foods and significantly lower sodium intake. Furthermore, the healthy food component scores and fatty acids ratio were at or above the 50th percentile. Conclusion: Small increases in consumption of WIC approved foods significantly improved diet quality among pregnant women in the program.
Read more“Treated as second class citizens” - the lived experience of obesity-related stigma: an IMI2 SOPHIA study
ABSTRACT Purpose Obesity-related stigma impacts on and shapes the physical and psychosocial wellbeing of individuals living with obesity. Often absent from the literature in the field is the voice(s) of those living with obesity capturing the nuances of the lived experiences of obesity-related stigma. Methods This study adopted a qualitative approach encompassing individual (n = 15) and photovoice method (n = 12), with a purposeful sample of patients accessing treatment for obesity within the healthcare setting during 2021. Analysis was undertaken using thematic analysis. Results Key themes developed from the analysis related to experiencing obesity-related stigma as exposure to external judgement, societal exclusion and felt environmental stigmatization. Exposure to external judgement was described as judgemental comments resulting in hypervigilance to societal judgement. Participants reported how being overlooked and ignored by others had various negative effects and compounded obesity-related stigma through societal exclusion. Public spaces lacking suitable equipment further made obesity-related stigma visible through felt environmental stigmatization when pursuing hobbies and in everyday life. Conclusions Obesity-related stigma had a profoundly negative impact on participants in this study, particularly in shaping social interaction, limiting life experiences and impacting psychosocial wellbeing.
Read moreEvidence supporting the initiation of HPV vaccination starting at age 9: Collection overview
Lessons learned from 2 years of influenza vaccinations in the UK and USA during the COVID-19 pandemic as respiratory viruses return
ABSTRACT During the COVID-19 pandemic, immunization programs for other respiratory infections, notably influenza continued worldwide but attracted less public or political attention than COVID-19 vaccinations. Due to non-pharmaceutical intervention measures the global influenza burden decreased substantially; but with lifting of restrictions a rebound in other respiratory virus pathogens is both plausible and likely. This article discusses lessons identified from the UK and USA, and provides recommendations for future influenza vaccination programs in light of emerging data from the southern hemisphere and the need for harmonization with COVID-19 vaccination, focusing on operational delivery and messaging to practitioners and the public.
Read moreThe lived experience of people with obesity: study protocol for a systematic review and synthesis of qualitative studies
BackgroundObesity is a prevalent, complex, progressive and relapsing chronic disease characterised by abnormal or excessive body fat that impairs health and quality of life. It affects more than 650 million adults worldwide and is associated with a range of health complications. Qualitative research plays a key role in understanding patient experiences and the factors that facilitate or hinder the effectiveness of health interventions. This review aims to systematically locate, assess and synthesise qualitative studies in order to develop a more comprehensive understanding of the lived experience of people with obesity.MethodsThis is a protocol for a qualitative evidence synthesis of the lived experience of people with obesity. A defined search strategy will be employed in conducting a comprehensive literature search of the following databases: PubMed, Embase, PsycInfo, PsycArticles and Dimensions (from 2011 onwards). Qualitative studies focusing on the lived experience of adults with obesity (BMI >30) will be included. Two reviewers will independently screen all citations, abstracts and full-text articles and abstract data. The quality of included studies will be appraised using the critical appraisal skills programme (CASP) criteria. Thematic synthesis will be conducted on all of the included studies. Confidence in the review findings will be assessed using GRADE CERQual.DiscussionThe findings from this synthesis will be used to inform the EU Innovative Medicines Initiative (IMI)-funded SOPHIA (Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy) study. The objective of SOPHIA is to optimise future obesity treatment and stimulate a new narrative, understanding and vocabulary around obesity as a set of complex and chronic diseases. The findings will also be useful to health care providers and policy makers who seek to understand the experience of those with obesity.Systematic review registrationPROSPERO CRD42020214560.
Read moreCan the Participant Speak Beyond Likert? Free-Text Responses in COVID-19 Obesity Surveys.
Research on lifestyle changes during the COVID-19 pandemic often relies on Likert-type scale question surveys. Survey participants respond to questions by selecting one of the numerically ordered choices, "Strongly Disagree"=1, "Disagree"=2, "Neutral"=3, "Agree"=4, and "Strongly Agree"=5. Analyzing Likert-type data requires statistical methods beyond approaches like linear regression. First, it is unclear if the distance between choices are truly equal. For example, are "Agree" and "Strongly Agree" more close than "Neutral" and "Agree? Second, summarizing results using traditional means makes little sense. For example, would a mean of 4.5 imply "Agree and a half"? Finally, participants tend to select more central choices and less extremes.
Read moreCorrection to: Understanding the Bariatric Patient Perspective in the National Patient-Centered Clinical Research Network (PCORnet) Bariatric Study.
In the original article the list of author names and affiliations were incorrect.
Vaccine hesitancy: Not a new phenomenon, but a new threat.
Vaccines have been recognized as one of the top 10 public health achievements of the 20th century. In 1998, a study on the connection between measles, mumps, rubella vaccine and autism was published by the now discredited Andrew Wakefield. That study was retracted in 2010, but the damage was already done. The purpose of this article is to review the history of vaccine hesitancy and discuss a successful paradigm for speaking with vaccine-hesitant parents. Discussion of immunizations related to public health law and religious exemptions will also be reviewed.
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