- Research Article
- 10.1007/s12268-024-2156-3
Explodierende Yersinien: Lyse spezialisierter „Soldatenzellen“ setzt Toxine frei
- Mar 01, 2024
- BIOspektrum
- Christian Rüter
Publications from 2021 to 2026
Showing 10 of 54 papers
Explodierende Yersinien: Lyse spezialisierter „Soldatenzellen“ setzt Toxine frei
Eine chemo‐enzymatische Modifizierung der 5′‐Kappe erhält die Translation und erhöht die Immunogenität der mRNA
Natürliche Modifikationen an der 5′-Kappe der mRNA beeinflussen die Translation und Immunogenität. Hier werden mRNAs mit nicht-natürlichen post-transkriptionellen Modifikationen auf Translation und Immunogenität getestet, was eine neue Strategie zur Anpassung von mRNA für therapeutische Anwendungen darstellt.
Read moreMetabolic flux screening of Saccharomyces cerevisiae single knockout strains on glucose and galactose supports elucidation of gene function
Optimisation of a polymer membrane used in optical oxygen sensing
Plasma concentration of intestinal- and liver-FABP in neonates suffering from necrotizing enterocolitis and in healthy preterm neonates
Minimally invasive suction sampling unit for interstitial fluid enhanced by electroosmotic mass transport
Electro-magnetic base technology for estremely sensitive immunosensors and DNA-chips.
We report on the development of an innovative electro-magnetic base technology for estremely sensitive sensors allowing the electrical detection of biological analytes like antigenes or DNA as well as a simple multiple detection of binding forces occurring at specific bonds between proteins. The technology is based on the strong impact of specifically captured magnetic microbeads on an electrical current generated in a fluid by a small sensor chip with an array of activated microelectrodes. The new technological principle with the on-chip detection of analytes will be suitable for large scale applications due to its mass production compatible technologies and allow an alternative way to monitor relevant substances without the consumption of critical additional solutions and reagents.
Read moreCrystal Structure of Maltose Phosphorylase from Lactobacillus brevis: Unexpected Evolutionary Relationship with Glucoamylases
Cover Picture
The cover picture shows the jumps of the calculated contact angle on a chemically patterned anisotropic surface as a function of surface energy (top). The surface was prepared from a dipalmitoyl phospholipide by the Langmuir–Blodgett technique and the resulting monolayer on the mica substrate was characterised by atomic force microscopy (bottom). Such nanostructured substrates are considered the first step towards microfluidic devices potentially important to chemistry, physics and biology. Further details are given in the contribution by Chi et al. on pages 187–191.
Read moreDetermination of fluorine, chlorine, bromine and iodine by a barrier discharge radiofrequency helium plasma.
バリヤー放電ラジオ波ヘリウムプラズマ発光法によるフッ素, 塩素, 臭素及びヨウ素を定量する方法を開発した. ヘリウムガスを通じたガラス管の外側に2枚の銅はくを巻き付け, 片方を接地し, 他方にラジオ波インパルス高電圧 (98kHz, 3.2kV) を与え, 放電を起こした. 放電から発せられる光を光ファイバーを介して, 電荷結合素子 (CCD) 付き分光器に導入し, 730~960nmの領域の光を測光した. フッ素 (733.2, 739.9nm), 塩素 (833.3, 837.6, 858.6, 894.8, 912.1nm等), 臭素 (827.2, 882.5, 889.8, 926.5nm等) 及びヨウ素 (905.8nm) の原子線が観測され, フッ素, 塩素については1~10μg, 臭素については0.1~1μgの範囲で, 量-応答の直線性が確認された. 各元素の発光強度を比較したところ, 臭素>ヨウ素>塩素>フッ素の順番であった.
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