Jiangxi Applied Engineering Vocational Institute

HighlightsA novel electrochemical fixed-abrasive polishing method is employed to achieve high material removal rates and obtain high-quality SiC surfaces.The mechanism of anodic oxidation reactions occurring on SiC surfaces has been elucidated, and the optimal electrolyte has been identified.The material removal process and optimal parameters for electrochemical fixed-abrasive polishing were systematically determined.

BackgroundAvian pathogenic Escherichia coli (APEC), a primary bacterial pathogen in poultry, induces substantial economic losses to the global poultry industry. The baicalin-copper complex (BCU) demonstrates markedly potentiated anti-inflammatory, anti-oxidant, and anti-tumor efficacy relative to either baicalin or copper in their isolated forms. The present study aimed to evaluate the protective effects of BCU against APEC-induced intestinal damage in chicks.MethodsSeventy-five one-day-old chicks were randomly assigned to five groups: control group (basic diet), E. coli group (basic diet), and BCU treatment groups (10, 20, and 40mg/kg BCU). After a 15-day feeding period, APEC infection was induced via pectoralis injection to ensure consistent systemic infection. Two days later, the chicks were weighed, and blood samples from the pterygoid vein and ileum tissue were collected for subsequent experiments.ResultsThe results showed that compared with the E. coli group, BCU reduced both diarrhea and mortality rates, with reductions in the BCU40 group to 27% and 7%, respectively. It also significantly up-regulated the mRNA expression of key intestinal physical barrier proteins (ZO-1, ZO-2, Claudin-1, Claudin-3, and Occludin) and chemical barrier components (Mucin 2 (MUC2) and avian β-defensins (AvBD2, AvBD4) (p < 0.05). Compared with the E. coli group, as shown by BCU markedly increased activities of antioxidant enzymes GSH-Px, CAT, SOD and reduced MDA level, which along with increased mRNA expression of the Nrf2-antioxidant signaling pathway (p < 0.05). Furthermore, BCU significantly down-regulated the mRNA expression of pro-inflammatory cytokines TNF-α, IL-1β, IL-6, IL-8, and significantly up-regulated the anti-inflammatory cytokines IL-10 and TGF-β (p < 0.05). Moreover, BCU inhibited the AKT/NF-κB signal pathway, as indicated by markedly reduced the protein expression of p-NF-κB and p-AKT (p < 0.01).ConclusionCollectively, the findings suggested that BCU effectively alleviates intestinal damage induced by APEC-infection through AKT/NF-κB signal pathway to modulate oxidative stress and inflammatory response.

IntroductionJiangxi Province possesses abundant genetic resources of local pig breeds, whose effective conservation is essential for maintaining biodiversity and sustainable utilization. Streptococcus suis is an important zoonotic pathogen that continuously threatens swine production systems and public health globally. This study aimed to investigate the epidemiological characteristics of S. suis among local pig breeds in Jiangxi Province.MethodsAn investigation was conducted on the prevalence and antimicrobial resistance profiles of S. suis in six local pig breeds from Jiangxi Province, including Gandong black pig, Hang pig, Ganxi two-end-black pig, Dongxiang spotted pig, Yushan black pig, and Binhu black pig.ResultsA total of 340 porcine nasal swabs were collected from six local pig breeds. 208 S. suis strains were isolated from 187 samples, with an overall isolation rate of 55.0%. The positive isolation rates of the six local breeds were 58.0, 80.0, 71.7, 51.7, 13.3, and 60.0%, respectively. Antimicrobial susceptibility testing revealed that >98% of isolates were susceptible to carbapenems (meropenem and imipenem), followed by doxycycline (71.6%), ceftiofur (65.9%), spectinomycin (64.4%), and amoxicillin (55.8%). High resistance rates were observed for tilmicosin (96.6%), sulfadiazine (92.8%), colistin (89.9%), apramycin (88.9%), chlortetracycline (87.5%), tiamulin (83.2%), and kanamycin (79.8%). 100% of isolates exhibited multidrug resistance, with significant variations in resistance patterns among breeds. Genotypic analysis identified ermB (macrolides), tetL (tetracyclines), and Sul2 (sulfonamides) as the predominant resistance determinants.DiscussionMultidrug-resistant S. suis strains have become widespread among local pig breeds. This study could provide evidence-based guidance for developing effective prevention and control strategies against S. suis infections and protecting valuable genetic resources of indigenous pig breeds.

This study focuses on rural youth and explores the impact mechanism of psychological resilience on leadership development from the perspective of human resource management. By analyzing the current status and challenges of leadership development among rural youth, a leadership development model based on the cultivation of psychological resilience is constructed. A systematic pathway including a curriculum system, a practical platform, evaluation feedback, and resource integration is proposed, aiming to provide theoretical and practical references for improving the leadership of rural youth.

Extracting natural active ingredients from plants is an effective way to develop and screen modern drugs. Psoralea corylifolia (PC) is a leguminous plant whose seeds have long been used as a Traditional Chinese Medicine to treat psoriasis, rheumatism, dermatitis, and other diseases. To date, several main compounds, including coumarins, flavonoids, monoterpene phenols, and benzofurans, have been identified from the seeds of PC. Among them, bavachinin is a type of flavonoid with various biological activities. In this article, the biological activities and mechanisms of action of bavachinin and its derivatives are reviewed. It includes the pharmacokinetic characteristics of bavachinin and its derivatives, as well as its prominent anti-inflammatory, antitumor, antibacterial, and antiviral pharmacological activities and related metabolic studies. Bavachinin displayed these activities through different receptors, such as peroxisome proliferator-activated receptors (PPARs), as well as multiple signaling pathways and enzyme systems. In summary, bavachinin and its derivatives have potential drug development value in many fields, such as anti-inflammatory, antitumor, nervous system disease, and diabetes. We believe that this review will lay a foundation for bavachinin-based drug development throughout the world.

ABSTRACT Driven by economic growth and rising living standards, eco-friendly and natural decorative materials are gaining favor. Bamboo filament decorative material (BFDM), as an emerging construction and decorative material, has garnered significant attention. However, its performance characteristics, especially in coating, dyeing, and bonding, are still unclear. This study explored the time effectiveness of low-temperature plasma treatment (LTPT) on BFDM surface modification. Four bamboo filament units (inner bamboo filament (IB), outer bamboo filament (OB), carbonised inner bamboo filament (CIB), and carbonised outer bamboo filament (COB)) were treated with a low-temperature plasma at a power of 60 W for 120 s. The treated specimens were stored in air for one (1) day, three (3) days, five (5) days, seven (7) days, or fourteen (14) days, and their surface changes were characterized using Scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS) techniques and contact angle measurements. The results showed that LTPT altered BFDM's micromorphology, causing surface etching and flocculent material formation. Active particles generated by LTPT reacted with the surface, leading to bond vibrations. The effectiveness of LTPT on BFDM was time-dependent, with IB lasting 5 days and OB, CIB, and COB lasting 3 days. Processing BFDM at peak surface activity after LTPT can enhance production efficiency and add value, benefiting manufacturers and installers.

The rise of community childcare services is not only an inevitable outcome of the transformation of economic and social development but also an important manifestation of the reconstruction of the relationship among families, society, and the state. Its driving forces are closely related to factors such as the normalization of dual-income families due to accelerated urbanization, the reduction of childcare time due to the accelerated pace of life, and the transformation of family childcare needs due to the popularization of scientific concepts. This paper analyzes the current development status and problems of community childcare services in China, selects different childcare models from around the world such as those in Northern Europe and the United States for comparison and research, analyzes their institutional logic and operational efficiency, and proposes a localized framework integrating systems, spaces, cultures, and technologies. It conducts in-depth exploration on the supply system, service network, intergenerational childcare community, and precise service system, aiming to provide references for the innovation and optimization of the community childcare service system with Chinese characteristics.