Judson University

This paper presents a novel framework designed to significantly accelerate these pipelines. By establishing granular data provenance and implementing intelligent reuse strategies, our system efficiently identifies and eliminates redundant computations. This approach tackles key challenges such as managing extensive data traces and accommodating non-deterministic operations through advanced duplication and hierarchical reuse techniques. Our framework seamlessly integrates with existing data processing environments, demonstrating substantial efficiency improvements and fostering faster iterative development cycles for data professionals.

The scientific literature on vertical gardens presents gaps in the systematization of botanical parameters related to modeling and simulation. To address these gaps, the article aimed to investigate and identify parameters and modeling processes necessary for configuring vertical greening systems in computer simulation software. The systematic literature review method was employed to gather all scientific publications from the past ten years. As a result, the article presents the processes for 3D modeling, the most common software, and information tables containing botanical parameters used for configuring vegetation. Additionally, the work provides an overview of studies conducted on this topic in Architecture in recent years, highlighting other gaps and shortcomings in knowledge for possible future research.

Wikihouse is an open-source, modular, digitally fabricated building system. Despite being the object of many studies in different countries, most of these experiences present a sequence of frames that generate only linear forms without formal variations. In this sense, this study aims to develop a geometry that allows more variations through the repetition of the same module. For this purpose, the research uses visual algorithmic modeling in Grasshopper to generate the geometry. As a result, we inserted the frames into a trapezium and mirrored the main profile, which kept the number of pieces. In future research, we intend to optimize the number of parts, reduce the cost and production time, and build a 1:1 module for validating its constructive stability.

It has become increasingly important for future business professionals to understand statistical computing methods as data science has gained widespread use in contemporary organizational decision processes in recent years. Used by scores of academics and practitioners in a variety of fields, Monte Carlo simulation is one of the most broadly applicable statistical computing methods. This article describes efforts to teach Monte Carlo simulation using Python. A series of simulation assignments are completed first in Google Sheets, as described in a previous article. Then, the same simulation assignments are completed in Python, as detailed in this article. This pedagogical strategy appears to support student learning for those who are unfamiliar with statistical computing but familiar with the use of spreadsheets. Supplementary materials for this article are available online.

Tay-Sachs disease (TSD) is a rare neurodegenerative disorder caused by mutations in the HEXA gene, which encodes the ɑ subunit of the enzyme β-hexosaminidase A. Lacking this key enzyme in GM2 ganglioside catabolism, individuals who are homozygous for HEXA mutations suffer from abnormal accumulation of GM2 ganglioside in brain and nerve cells, ultimately resulting in the progressive deterioration of the central nervous system. TSD is one of three disorders characterized by β-hexosaminidase deficiency; Sandhoff disease (SD) and the AB variant arise by mutations in the HEXB and GM2A genes respectively, which disrupt other points of GM2 ganglioside degradation. Characterized by developmental delay and stagnation, muscular weakness, coordination deficits, seizures, and eventual hearing and vision loss, these three disorders are clinically indistinguishable and occur in three forms defined by age of onset. While there is a much higher incidence of TSD in the Ashkenazi Jewish population, community carrier screening and counseling initiatives have reduced disease prevalence to about the equivalent of non-Jewish populations; however, such efforts have raised ethical concerns in the Jewish community that are increasingly relevant in light of scientific and medical advancements. Currently, treatments for TSD and its related disorders focus on symptom management, with gene therapies and the application of modified CRISPR-Cas-9 technology being explored.

When educators have difficulty accessing peer-reviewed research, it is inequitable to expect them to compete with educators who have access to a plethora of resources. Inequities have been a historically-identified educational problem; however, the forced online learning that occurred during COVID-19 restrictions amplified discrepancies experienced by tertiary educators. Scholars who were forced to work without strong information communication technologies infrastructure and who experienced limited access to online resources struggled more than those that had 24-hour uninhibited access. Education came to a near standstill for those that could not easily move their activities online. Prior to the pandemic, individuals working with curricula were already feeling handicapped by the lack of access. When physical libraries were closed, it became nearly impossible for many to move forward. This chapter explores the changing publishing paradigms, particularly the role of OA and how increasing open dissemination of scholarly outputs can reduce inequities in curricula and research activities.

We describe an inexpensive magnetic cell patterning method as a tool for protozoologists. The ciliate Vorticella convallaria is useful for various biofluidics applications. Here, we show that V.convallaria will ingest metal beads and that permanent magnets can be used to pattern cells in Petri dishes or a microfluidic device. Patterning is reversibly achieved by placing magnets at the point of desired cell attachment. Analogous magnetic manipulation could be performed using other phagocytic cells.

Sohn, Opfer und guter Hirte. Studien zum Brief an die Hebräer.