Le Mans Université

Le succès de Suzanne et les Vieillards en peinture, à une période où le nu fait l’objet de diverses attitudes ou réactions morales et esthétiques en Europe, nous a amenée à nous interroger sur le sens que peut avoir la prédilection pour la scène de la toilette au regard de l’intime et de l’intimité, explorée par les peintres. Notre corpus, qui comprend des œuvres picturales de quatre pays, nous a permis d’analyser non plus la seule nudité dans son rapport au voyeurisme mais l’approche émotionnelle du personnage féminin comme objet de regards emboîtés (du spectateur et du peintre) sur l'intimité comme espace protégé et réservé du corps et sur la violation de cet espace. Ces regards sont autant d'interrogations venant de l'artiste et, sans doute, de voies entrouvertes sur sa propre intimité

A correlation of the tectonostratigraphy and tectonic structures across the Attic-Cycladic belt to the Dodecanese islands and the western Menderes massif is required to reconstruct the pre-Eocene high pressure-subduction crustal architecture of the eastern Mediterranean. Notable, the transition from Cyclades to Dodecanese resides above a subduction slab tear that formed in the Miocene, which has offset the downgoing plate by >100 km, yet few tectonic structures exposed at the surface record the deeper geodynamic phenomenon. Residing along the NE-SW striking Santorini-Amorgos Fault Zone, the Astypalaia Platform exposes unmetamorphosed to weakly metamorphosed Triassic-Cretaceous neritic limestones, including Rudist- and Megalodont-bearing units. Unconformably above the limestone is an Eocene Nummulitic limestone-flysch package that contains km-scale marble and mafic volcanic olistoliths. The sequence, here named Analipsi subunit, was deformed into a series of NW-SE trending upright folds that preserves ductile top-to-N structures. The Vardia subunit, a weakly deformed Jurassic(?)-Cretaceous marble and limestone sequence capped by Eocene flysch, was thrust northward over the Analipsi subunit along the Vardia Thrust. This contact is characterized by a ductile strain gradient that increases toward the base of the hanging wall, marked by several tens of meters of marble ultramylonites on top of cataclasites. Top-to-S cataclasis overprints the earlier shortening structures localizing at the base of the Vardia Thrust. Unlike the other Dodecanese islands to the east, neither Variscan nor Paleozoic rocks are exposed on Astypalaia, indicating a higher structural level is present. Zircon (U-Th)/He dates from eight Eocene Analipsi flysch samples are partially reset, yielding single crystal ages of 130 Ma to 30 Ma, lacking a correlation to effective uranium concentrations, and exhibiting a dominant Paleocene-Early Eocene population. The overlap of the younger ZHe cooling dates and the depositional age of the Nummulite-bearing flysch suggests deposition, lithification, and subsequent deformation occurred rapidly in the Middle to Upper Eocene and under shallow crustal (

Abstract The hydrophobic effect, the primary driver of methane confinement within crystalline water cages, stabilizes vast reservoirs of methane clathrate hydrates across Earth and other planetary bodies. While high pressure is known to drastically alter both the stoichiometry and intermolecular dynamics of gas hydrates, understanding these transformations has been hindered by the limited resolution of previous studies. Here, using in situ high-pressure single-crystal X-ray diffraction, we demonstrate a pressure-driven increase in methane content and the emergence of a previously unknown clathrate hydrate stable at pressures of 1.3-2.1 GPa. The novel phase, MH-IIb, is a maximally filled clathrate phase with an H 2 O:CH 4 ratio up to 3.40. We show that the transition to MH-IIb is driven by methane–methane steric repulsion, which, with pressure, overcomes classical methane–water hydrophobic interactions and forces formation of unconventional C–H···O hydrogen bonds. Our results indicate that the high-pressure, maximally filled clathrate MH-IIb may serve as a methane reservoir in the outer part of the differentiating core of early Titan, thereby impeding degassing and accounting for the delay in the formation of Titan’s methane-rich atmosphere. Beyond the solar system, this pressure-induced methane-trapping mechanism extends to water-rich exoplanets, allowing their deep interiors to retain vast carbon reservoirs, suggesting that atmospheric surveys may fundamentally underestimate these planets' total carbon inventory.

This research aims to provide a framework for identifying vestiges of vertebral haemangioma (VH), a benign tumour originating from the cells that form blood or lymphatic vessels, in archaeological human skeletal remains. The macroscopic alteration was observed in the fourth thoracic vertebral body of a female aged 2535 years at death from the necropolis of Pontecagnano (Salerno, Italy), dated to 725650 BCE; the adult individual was associated with the skeletal remains of an infant. Macroscopic assessment was combined with stereomicroscopy, micro-CT, and 3D reconstruction. Macroscopically, areas of cortical bone loss enabled evaluation of trabecular thickening and rarefaction. Radiographically, small punctuate areas of sclerotic bone resulting from the replacement of the normal cancellous bone by vertically oriented and thickened vertical trabeculae were typified as polka-dot on the axial plane and corduroy sign on the sagittal image. The bone alterations are considered pathognomonic of an intraosseous VH. This study, which describes one of the few cases of VH in the palaeopathological literature, highlights the importance of combining macroscopic assessment and advanced imaging techniques for the diagnosis of VHs in archaeological human skeletal remains.

Contexte : La sclérose en plaques (SEP) est une maladie neurologique chronique caractérisée par une altération progressive des fonctions motrices, notamment de la coordination. Malgré son importance clinique, l’évaluation spécifique de la coordination reste peu développée. Cet article présente le processus de traduction et de validation de la version française de la Comprehensive Coordination Scale (CCS), un outil combinant l’évaluation de la performance motrice et de la qualité du mouvement. Méthode : L’étude s’est déroulée en deux temps : (1) une phase de traduction et de rétro-traduction suivant les recommandations internationales ; (2) une phase de validation impliquant 16 patients atteints de SEP, évalués deux fois à une semaine d’intervalle pour mesurer la reproductibilité inter-évaluateur et intra-évaluateur. Des mesures cliniques ont été effectuées : le test de marche de 6 minutes (TM6) et la Fatigue Severity Scale (FSS).Résultats : Les résultats montrent une bonne fiabilité inter-évaluateur (ICC=0,85; p=0,002) et une excellente fiabilité intra-évaluateur (ICC=0,91; p=<0,001). On observe une forte corrélation entre le TM6 et la CCS (r=0,632; p=0,010), et aucune corrélation entre la CCS et la FSS (r=0,282; p=0,290).Conclusion : La CCS permet une évaluation fine et fiable de la coordination motrice des personnes atteintes de SEP, et pourrait être intégrée aux pratiques cliniques et de recherche.

International audience

In this work, we report the synthesis and characterization of the new hybrid inorganic-organic compound (C5H7BrN3)6(BiCl5)3, which crystallizes in the triclinic space group P̄1. The crystal structure, determined from X-ray powder diffraction, reveals an asymmetric unit built from one [Bi2Cl10]4- dimer, one independent [BiCl5]2- anion, and six neutral 2,3-diamino-5-bromopyridinium molecules. This arrangement highlights the coexistence of distinct bismuth chloride units stabilized by an extensive network of hydrogen bonding and electrostatic interactions with the organic moieties. Density Functional Theory (DFT) calculations performed at the B3LYP/LANL2DZ level provide optimized structural parameters and vibrational assignments consistent with the experimental IR spectrum recorded in the 400-4000 cm-1 range. The optical properties investigated via solid-state UV-vis diffuse reflectance reveal an indirect bandgap of 2.6 eV, confirming the semiconducting behavior of the material. The combination of structural features, optical response, and theoretical insights underscores the potential of (C5H7BrN3)6(BiCl5)3 as a promising hybrid material for semiconductor and optoelectronic applications.

International audience

Geomarketing revolutionizes retail location strategies by leveraging Geographic Information Systems (GIS) and geolocation technologies, shifting from traditional intuition-based approaches to precise, data-driven decisions. It enhances retail visibility, customer engagement, and operational efficiency through detailed spatial analysis, sales forecasting, and consumer behavior understanding. By integrating spatial analysis with the retail marketing mix, it underscores the critical role of 'Place' in optimizing retail strategies. Despite challenges in data management and technology integration, the future of geomarketing looks promising, with artificial intelligence and machine learning poised to further advance spatial analytics and decision-making processes in the retail industry.

Nephrosplenic space entrapment (NSE) has reported recurrence rates of 8%‒23%, and closure of the nephrosplenic space (NSS) has been shown to lower the incidence. Described techniques for nephrosplenic space closure (NSC) with concurrent left dorsal displacement (LDD) of the colon at the time of surgery consist of reducing the displaced colon prior to closure. A retrospective study was performed to evaluate the medical records of horse undergoing NSC between 2017 and 2024. A total of 18 horses with LDD at time of NSC and 21 without displacement at time of NSC were evaluated. Short- and long-term outcomes were compared. Surgical time was similar for both groups. No significant association was found between LDD at time of surgery and the presence of signs of colic after the surgery. A statistically significant decrease in number of colic episodes after surgery was seen in both groups, and none of the horses were represented with an NSE again. Retrospective study design and the associated potential for bias. Full-laparoscopic closure of the NSS with a left dorsally displaced colon, and without prior repositioning of the colon, in subacute or chronic cases, is technically feasible, and safe and does not increase the total surgical time.