LifeForce Homoeopathy (India)

Introduction At the 2024 election, Americans faced a pivotal choice about their nation's global trajectory, amid intensifying debate over the future of U.S. hegemony. This study investigates whether the United States is experiencing a phase of hegemonic decline, signaling the end of its era as the world's leading great power, or whether its power can persist or even be revitalized. Methods To evaluate this, we employ a mixed-methods approach. We use quantitative modeling to analyze historical power lifecycles of previous hegemons, identifying inflection points and estimating the potential end dates of U.S. dominance. In parallel, we use qualitative analysis of recurring historical markers of decline - such as strategic overreach, domestic polarization, and eroding global legitimacy - to assess their presence in current U.S. conditions. Results Our quantitative model projects potential turning points in American global primacy between 2032 and 2067. The qualitative analysis reveals that the United States currently exhibits several key recurring features of great-power decline, including internal division, weakened alliances, reduced moral authority, and challenges from rising powers with competing rule-setting ambitions. Discussion While the United States maintains significant multidimensional strengths, these findings suggest that it may be transitioning into a phase of relative or systemic decline. This framework offers a foundation for further study into the drivers, agents, and timing of hegemonic transition, as well as how U.S. administrations may shape the durability or erosion of American leadership in the evolving international order.

Abstract Diabetic nephropathy (DN) is a chronic kidney disease that occurs in patients with diabetic mellitus. In the United States of America, one in three people with diabetes suffers from DN. Globally, DN occurs in 30%–40% of patients diagnosed with diabetes. Circular ribonucleic acids (circRNAs) are non-coding, closed-loop RNAs that play critical roles in regulating gene expression by sponging microRNAs (miRNAs). Recent studies have implicated circRNAs in the regulation of various diseases including DN. We delineate circRNA biological networks from the evidence gleaned from clinical studies. Further, we elucidate circRNA-associated signal transduction pathways in the pathogenesis of DN. Taken together, this will facilitate the discovery of novel circRNA and/or miRNA biomarkers for diagnostic and/or therapeutic intervention in DN.

ABSTRACT Title Prevalence of Post-Covid Complications in a Follow-Up Survey of Participants of Two Randomized Controlled Trials of Individualised Homoeopathy on Moderate and Severe Cases of COVID-19: A Cross-Sectional, Telephonic Survey Background COVID-19 pandemic, declared by WHO in March 2020, witnessed widespread relapses and persistent symptoms across successive waves. Evaluating post-COVID status of individuals treated with adjunct therapies is crucial to understanding their long-term outcomes. Objective This survey aimed to assess effectiveness of individualized homoeopathy as an adjunct therapy alongside conventional treatment in moderate-to-severe, oxygen-dependent COVID-19 cases. Methods A Telephonic survey was conducted from April 1 to May 29, 2022, including 219 participants discharged from AIIMS, Jhajjar, and St. George Hospital, Mumbai, who participated in placebo-controlled trials. The Post-COVID-19 Functional Status (PCFS) Scale assessed health outcomes, comparing add-on Homoeopathy (AoH) and add-on placebo (AoP) groups. Results The mean scores of PCFS Scale between groups were compared using chi-square test. The AoH group exhibited mean PCFS score of 0.83 ± 1.47 compared to 1.33 ± 1.63 in AoP group (mean difference: -0.49; P=0.04). Incidences of post-COVID complications like diabetes, hypertension, and exertional breathlessness were lower in AoH group, with significant improvements in functional ability (57% in AoH vs. 43% in AoP). No cases of anxiety, pneumonia, or kidney disease were reported in AoH group, contrasting with low incidences in AoP. Conclusions As an adjunct to standard COVID-19 care, Homoeopathy demonstrated potential in improving functional outcomes, helping patients combat post-COVID symptoms effectively. Further research is warranted to validate these findings.

In the conditions of the right bank of the Saratov region, the responsiveness of sugar sorghum varieties (Kapital, Sahara, Seviliya, Volonter, Chaika) to the application of humic preparations (K-Humate-Na with trace elements, Reasil Forte Carb-N-Humic and Reasil Forte Seed Start) was studied at the experimental field of “Rosorgo”. The aim of the research was to determine the greatest stimulating effect of humic preparations on selection-valuable traits, including seed yield. Pre-sowing treatment of seeds and vegetative plants with K-Humate-N with trace elements (a dose of 1.0 l/t+1.0 l/ha) proved to be the most effective in cultivating Chaika, Kapital and Sahara varieties. Depending on the variety, this allowed an additional 0.94-1.22 t/ha of seeds to be collected. The influence of Reasil Forte Carb-N- Humics (dose 1.0 l/t+2.0 l/ha) on the yield of Seviliya and Volonter varieties was quite high. The use of the drug increased seed productivity by an average of 0.85-0.94 t/ha over two years of testing. Humic preparations had a stimulating effect on the sowing quality of seeds, the length of the panicle and the weight of seeds from a single panicle.

The present research is performed while turning of JIS S45C hardened structural steel with the multilayered (TiN-TiCN-Al2O3-TiN) CVD coated carbide insert by experimental, modelling and optimisation approach. Herein, cutting speed, feed rate, and depth of cut are regarded as input process factors whereas flank wear, surface roughness, chip morphology are considered to be measured responses. Abrasion and built up-edge are the more dominant mode of tool-wear at low and moderate cutting speed while the catastrophic failure of tool-tip is identified at higher cutting speed condition. Moreover, three different Modelling approaches namely regression, BNN, and RNN are implemented to predict the response variables. A Back-propagation neural network with a 3-8-1 network architecture model is more appropriate to predict the measured output responses compared to Elman recurrent neural network and regression model. The minimum mean absolute error for VBc, Ra and CRC is observed to be as 1.36% (BNN with 3- 8-1 structure), 1.11% (BNN with 3-8-1 structure) and 0.251 % (RNN with 3-8-1 structure). A multi-performance Optimisation approach is performed by employing the weighted principal component analysis. The optimal parametric combination is found as the depth of cut at level 2 (0.3 mm)-feed at level 1 (0.05 mm/rev) – cutting speed at level 2 (120 m/min) considered as favourable outcomes. The predicted results were validated through a confirmatory trial providing the process efficiency. The significant improvement for S/N ratio of CQL is observed to be 9.3586 indicating that the process is well suited to predict the machining performances. In conclusion, this analysis opens an avenue in the machining of medium carbon low alloy steel to enhance the machining performance of multi-layered coated carbide tool more effectively and efficiently.

In 2013-2015 there was studied the effectiveness of products based on humic acids and chelated microfertilizers during red beet cultivation on irrigated dark chestnut soils of the Saratov Transvolga region. The objects of the study were products produced by Life Force LLC, RPE and Bordo red beet variety. The purpose of the research was to determine the most effective application methods of humic acid salts and fertilizers, containing micro (boron, manganese), meso (calcium) and macro (nitrogen), which can increase the productivity of root crops and improve their quality. In field experiments it has been established that spraying vegetative plants of red beet with a solution of Reasil® micro Hydra Mix increased the yield of commercial root crops by 7.17 t/ha for an average of three years (by 28 % to control). The application of a K-Humate-Na increased the yield by 3.26 t/ha (by 13% to the control). The maximum yield of root crops within our experiments was obtained with the application of Reasil B along with Reasil® micro Hydramix (34.02 t/ha). Similar results were obtained with the combination of Reasil® micro Hydramix and Reasil® Carb-N-Humic. As a rule, the fertilizers, applied in the experiments, had a positive effect on the yield of commercial products and lowering the proportion of substandard products. Humic acid salts and chelated fertilizers enhanced the accumulation of dry matter, increased the content of nitrogen, phosphorus, potassium, the amount of sugar and vitamin C in fruits. The content of nitrate nitrogen in fruits was about 13-14 times lower than maximum permissible concentration (MPC). The removal of macronutrients from the soil with the yield of red beet was increased significantly under the influence of humic acid salts and fertilizers.