London Metropolitan University

This editorial introduces the special issue on “Expanding Conceptions for Research on Possibility” and surveys the papers submitted by over 15 scholars from diverse fields and disciplinary backgrounds. Expanding our conceptions of research beyond traditional boundaries and silos, the papers in this volume articulate research as a world-disclosing and “world-making” practice, concerned not only with how the “world is” but with creating “a world to come”. Displaying a great variety of research methods and approaches, the articles delineate specific theoretical and methodological strategies for expanding the sense of the Possible in diverse educational and social contexts. The expansion of possibility research and practice is further discussed in relation to theoretical expansions, pedagogical expansions, more-than-human expansions, and possibility and futures thinking. The editorial concludes by highlighting the relevance of possibility research in the context of current global developments.

has been to provide accurate and useful information on this topic, both for the general population and for professionals, by presenting a diverse and compelling collection of articles that will equip professionals with practical tools and foster interest in sexological science among the public.An essential aspect of science is the availability of reliable and valid measurement tools that allow for accurate assessment of sexological variables in individuals, and this special issue includes three articles on this topic. The article Psychometric Evaluation of the Abbreviated Hungarian Faking Orgasm Scale for Women (Csány et al., 2024) examines the factorial structure of a scale designed to explore the underlying motivation in cases of faked orgasm. The article Development of a Cross-Cultural Scale on Attitudes Toward Gender and Sexual Diversity (AGSD) (Oleas et al., 2025) presents the development of a scale aimed at assessing attitudes toward gender and sexual diversity. This scale constitutes a valuable tool for both clinical and educational contexts, where attitudes toward gender and sexual diversity can be evaluated to promote changes toward healthier attitudes. The third article focused on instrument validation is entitled Validation of the Brief Index of Sexual Functioning for Women and Men (BISF-W and BISF-M) in an Italian Sample (Panzeri et al., 2024). This study validates an assessment instrument originally designed for women and develops a version for men, in its Italian adaptation, to evaluate sexual experiences in both clinical and experimental settings. (Paramio et al., 2024), addresses concerns related to sexual behaviours in young people within non-psychopathological contexts.Overall, this special issue constitutes a highly informative and timely contribution for researchers and clinicians seeking to stay up to date in the field of sexuality and sexual dysfunctions.Cabello-García, M. A., Sánchez-Sandoval, Y., & García-Rojas, A. D. (2024).Influence of personality disorders on sexual behaviours and response to treatment of psychogenic erectile dysfunction in phosphodiesterase 5 inhibitor non-responders.

Collaborative projects under the Horizon Europe Framework Program of the European Union typically involve a large number of partners from multiple countries. Data-centric projects, among them, often require integration of disparate data source formats and collection methods, leading to complex data management architectures and policies. This article is an extended version of an article presented at the 1st International Conference on Big Data Analytics and Applications (BDAA’2025). It explores design decisions, organisational principles, and technological solutions to address these challenges by focusing on data integration of data sources and the hybridisation of data services. This experience was gathered while working on DiverSea, a project dedicated to the analysis of biodiversity dynamics along European coastlines—ranging from the Black Sea to the Mediterranean and the North Sea. While grounded in established technologies, the project’s takeaways offer valuable insights for environmental data projects across aquatic, terrestrial, and atmospheric domains.

Background: AMR is a public health concern which leads to high global morbidity and mortality. Immunocompromised patients, who are more susceptible to contracting potentially life-threatening infections, are faced with reduced treatment options due to emerging AMR. Ceftolozane/tazobactam is a novel β-lactam/β-lactamase inhibitor which displays effectiveness against resistant Gram-negative infections. Methods: SPECTRA was a multinational, observational study conducted in seven countries including 617 patients who received ≥48 h of ceftolozane/tazobactam. Medical-record data were collected up to 6 months before treatment and 30 days after the final dose or until death. This analysis describes clinical outcomes and healthcare resource use in patients with sepsis or who were immunocompromised, specifically in patients with hematologic malignancy with and without solid tumor, febrile neutropenia, and solid organ transplant patients. Results: Clinical success ranged from 50.0% in patients with hematologic malignancy and solid tumor to 69.4% in 38 patients with febrile neutropenia. All-cause in-hospital mortality was 23.1-42.9%, with the lowest rates in patients with solid organ transplant. ICU admission was 46.4-68.2% across subpopulations (excluding febrile neutropenia) with the lowest rates in patients with hematologic malignancy. ICU length of stay was lowest within transplant patients (9 days) and highest within the hematologic malignancy and solid tumor population (32 days). Conclusions: The results from this sub analysis of SPECTRA showed that ceftolozane/tazobactam was associated with clinical success in the selected immunocompromised and sepsis patient populations and may lead to reduced morbidity, mortality, and healthcare-resource use. Further research is required to standardize treatment protocols and improve patient outcomes.

Correction to “High-risk neuroblastoma stage 4 (NBS4): multi-target inhibitors for c-Src kinases (Csk) and retinoic acid (RA) signalling pathways” by Gerges A and Canning U. Explor Drug Sci. 2025;3:1008109. DOI: 10.37349/eds.2025.1008109. The authors have recognized an error in the published paper. This correction does not affect the scientific content, interpretation of the results, or the conclusions of the paper. The authors apologize for any inconvenience caused to the readers by this error. The original uncorrected PDF can be accessed from https://www.explorationpub.com/uploads/1008109_1st.pdf.