Meningitis Now

Industri 4.0 ditandai meningkatnya penggunaan teknologi informasi. Toko yang berdiri sejak 1950 ini belum memanfaatkan teknologi informasi dalam promosinya. Tugas akhir ini bertujuan merancang media promosi dengan media sosial Instagram karena pertumbuhan penggunanya tinggi dan media cetak. Penggunaan Instagram dan media cetak bertujuan mempromosikan Toko Sido Mukti untuk dapat bersaing di era industri 4.0. Metode kualitatif digunakan untuk mendeskripsikan suatu obyek. Teknik perancangan diawali dengan pengambilan data melalui observasi, wawancara, dan dokumentasi. Dari observasi didapatkam data keadaan toko dan lingkungannya. Dari wawancara didapatkan sejarah toko, perkembangan toko, dan keunggulan produk. Data tersebut didokumentasikan dengan rekaman suara, foto, serta video. Tema desain yang digunakan adalah vintage serta ilustrasi cross-hatching. Keluaran akhirnya berupa desain Instagram dan media cetak pendukung lainnya. Kesimpulannya adalah segala jenis usaha sebaiknya mengikuti perkembangan yang ada agar mampu bersaing tanpa meninggalkan keunggulan yang telah ditawarkan. Perancang selanjutnya diharapkan agar mampu mengeksplorasi keunggulan Toko Sido Mukti yang belum dimunculkan.

I. INTRODUCCIÓNLa obstrucción de la vía aérea constituye una situación emergente, es por tanto algo ajeno a la naturaleza del ser humano; constituye un evento accidental y súbito en pediátricos sanos previamente; el mismo clínicamente presenta dificultad respiratoria súbita que puede ser tan fatal y conducir a la muerte (1).Según la Sociedad Americana del corazón, la importancia de reconocer y diferenciarlos es trascendente (2).Es relevante mencionar que la concepción es concreta por tanto el objetivo del capítulo es ofrecer un correcto manejo de esta emergencia sanitaria (2).En orden de frecuencia el cuerpo extraño puede llegar a ocluir la vía aérea superior e inferior: laringe, tráquea, bronquios, por lo que el actuar debe ser inmediato.Cabe aclarar que la obstrucción de la vía aérea de causa infecciosa tipo epiglotitis

BackgroundUrgent and emergency care health services are overburdened, and the use of these services by acutely ill infants and children is increasing. A large proportion of these visits could be sufficiently addressed by other health care professionals. Uncertainty about the severity of a child’s symptoms is one of many factors that play a role in parents’ decisions to take their children to emergency services, demonstrating the need for improved support for health literacy. Digital interventions are a potential tool to improve parents’ knowledge, confidence, and self-efficacy at managing acute childhood illness. However, existing systematic reviews related to this topic need to be updated and expanded to provide a contemporary review of the impact, usability, and limitations of these solutions.ObjectiveThe purpose of this systematic review protocol is to present the method for an evaluation of the impact, usability, and limitations of different types of digital educational interventions to support parents caring for acutely ill children at home.MethodsThe review will be structured using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and Population, Intervention, Comparator, and Outcome (PICO) frameworks. Five databases will be systematically searched for studies published in English during and after 2014: Medline, EMBASE, CINAHL, APA PsycNet, and Web of Science. Two reviewers will independently screen references’ titles and abstracts, select studies for inclusion based on the eligibility criteria, and extract the data into a standardized form. Any disagreements will be discussed and resolved by a third reviewer if necessary. Risk of bias of all studies will be assessed using the Mixed-Methods Appraisal Tool (MMAT), and a descriptive analysis will be used to evaluate the outcomes reported.ResultsThe systematic review will commence during 2021.ConclusionsThis systematic review will summarize the impact, usability, and limitations of digital interventions for parents with acutely ill children. It will provide an overview of the field; identify reported impacts on health and behavioral outcomes as well as parental knowledge, satisfaction, and decision making; and identify the factors that affect use to help inform the development of more effective and sustainable interventions.International Registered Report Identifier (IRRID)PRR1-10.2196/27504

Objectives:To identify the clinical profile, etiology, and outcome of culture-positive mycotic keratitis in a tertiary referral centre in the northeastern part of Malaysia.Materials and Methods:A retrospective review of all patients with culture-positive mycotic keratitis in Hospital Universiti Sains Malaysia over a 3-year period, from January 2015 to December 2017.Results:This study included 27 eyes of 27 patients treated for mycotic keratitis based on a positive fungal culture. The most common predisposing factor was ocular trauma, in 22 patients (81.5%). Eleven patients (40.7%) had a presenting visual acuity worse than 6/60, due to central ulcer involvement. Approximately half of these (6 patients) experienced visual improvement post-treatment. Fusarium spp. was the most common fungus isolated (37%), followed by non-sporulating fungi and Curvularia spp. Three patients (7.4%) had corneal microperforations, which healed after gluing and bandage contact lens application. One patient (3.7%) required tectonic penetrating keratoplasty and 1 patient (3.7%) underwent evisceration. The final visual acuity was 6/18 or better in approximately half (14 patients) of our cohort and worse than 3/60 in approximately 20% (5 patients).Conclusion:Mycotic keratitis occurred mainly in males and secondary to ocular trauma. The most common organism isolated was Fusarium spp. Although treatment may improve vision, the visual outcome is guarded.

This study applied size and shape analyses through traditional and geometric morphometrics to quantify the differences between three taxa: Lathyrus sativus (grass pea), Lens culinaris (lentil) and Vicia faba (broad bean). This analysis represents a pilot study in view of a wider future application of this technique to identify the role of legumes throughout the Western Mediterranean in the Bronze and Iron Ages. Here, we quantify the morphological differences of seed species from the site of La Font de la Canya (Catalonia, Spain), an Iron Age (625–150 bc) centre of storage and trade which delivered a vast assemblage of cereal, fruit and legume remains. Our results reveal that seed outline analyses have a greater potential of prediction than length measurements. The combination of the two, however, leads to even more precise predictions. Moreover, the quantitative differences between the lentils of the different samples confirm the potential of these analyses to further identify intra-species morphotypes.

Penelitian ini bertujuan untuk memperoleh gambaran empati mahasiswa etnis Betawi program studi Bimbingan dan Konseling pada beberapa Universitas di DKI Jakarta. Metode yang digunakan adalah deskriptif dengan jenis penelitian survey. Populasi dalam penelitian ini berjumlah 30 mahasiswa etnis Betawi program studi Bimbingan dan Konseling dari 4 Universitas di DKI Jakarta; Universitas Negeri Jakarta (UNJ), Universitas Katolik Atma Jaya, Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA), dan Universitas Islam Assafi’iyah. Instrumen yang digunakan adalah instrumen Empati dari Darrick Jollife dan David P Farrington (2006) dengan r = 0,857. Pengujian instrumen diolah dengan menggunakan SPSS 17.0.Uji Validitas dari 20 butir pernyataan terdapat 17 butir pernyataan yang valid dan 3 butir pernyataan yang tidak valid.Butir-butir pernyataan yang tidak valid di revisi dan diperbaiki redaksinya menjadi pernyataan baru. Hasil penelitian empati mahasiswa etnis Betawi program studi Bimbingan dan Konseling berada pada kategori tinggi sebesar 73%, pada kategori sedang diperoleh sebanyak 27%, sedangkan pada kategori rendah diperoleh 0%. Berdasarkan hasil yang didapatkan, bahwa sebagian besar empati mahasiswa etnis Betawi Bimbingan dan Konseling berada pada kategori tinggi.Implikasi dalam penelitian ini adalah untuk mahasiswa yang berada pada ketegori sedang, untuk lebih meningkatkan empatinya, yaitu dengan memanfaatkan media seperti televisi, ataupun film yang mengandung unsur-unsur empati.Dengan melihat langsung melaui film dapat menumbuhkan secara lansung perasaan empati kita pada film tersebut, dan bagaimana kita merespon atau memandangnya.

I read with interest Louise Rowland's practice profile on meningococcal B disease and the importance of early detection (learning zone August 1).

Allogeneic cardiosphere-derived cells (CDCs) have proven safe and effective in a small animal model of myocardial infarction (MI), and have been shown to act primarily via paracrine mechanisms to stimulate endogenous regeneration. The present translational study tested allogeneic CDCs in a large animal model (mini-pigs). To establish a robust allogeneic model, all pigs were swine leukocyte antigen (SLA) typed by PCR. A male donor and female recipients with full SLA I, II mismatch were used. Pigs underwent balloon occlusion of the LAD for 2.5 hours, followed by reperfusion. Two weeks later, 12.5 million CDCs (n=8) or vehicle (n=6) were infused. Animals were sacrificed 2 weeks or 2 months post-infusion to assess the cellular (histology using a clinical rejection scale) and humoral (donor-specific antibodies, complement-dependent cytotoxicity) immune responses, as well as cardiac function (left ventriculography, hemodynamics, morphometry). Numerous in-life assessments for safety were performed and CDC engraftment was assessed by FISH for Y chromosome. All immunological assays indicated an undetectable response to CDCs. Cardiac enzymes and systemic inflammation showed no differences between groups. There were no systemic histological findings related to CDCs. CDCs did not permanently engraft, with <0.1% persisting 2 weeks post-infusion and none evident 2 months post. Despite evanescent engraftment, functional benefits were seen following infusion of CDCs. Ejection fraction (EF) and infarct size (IS) were significantly improved in CDC-treated animals compared to vehicle-treated 2 weeks post-infusion (EF: 48.6±2.1% vs 38.2±2.6%, p<0.05; IS: 9±2 vs 14±2%, p<0.05). At 2 months, EF still trended higher in CDC-treated animals (42±5 vs 32±10%, p=0.09), and IS still trended lower (14±4 vs 16±7%, p=0.60). Pressure-volume relationships revealed a trend for enhanced contractility in CDC-treated animals (Emax: 3.2±2.2 vs 1.0±1.1 mmHg/mL, p=0.26). The magnitude of the functional benefits was similar to that seen in a prior pig study using autologous CDCs. Overall, results of the present study demonstrate that allogeneic CDCs are largely equivalent to autologous in terms of efficacy, and elicit no detectable immunological response or safety concern.

I challenge readers to climb the awe-inspiring Mount Kilimanjaro to help raise money for meningitis research.