NanoDesign (Slovakia)

"Tower House" is a three-dimensional one-room house that expands vertically by laminating floors without partitioning by fittings and partition walls, showing one way of urban housing. A house called "Skip-floor type" is a house in which floors with different levels are connected three-dimensionally, creating open interior space. Compared to houses with rooms as the main unit, houses with "floors" as the main unit are characterized by open and cohesive interior space, and this study refers to these houses as "open laminated houses". Open laminated house is often found in narrow sites due to the subdivision of site in recent years, and various design can be seen depending on sizes, connections on the flow line, level differences, etc. with the "floor" forming each layer as a composition unit. The "floor" is an element that can create integral unity or ambiguous and ambiguous unity inside the room. Therefore, in open laminated house whose main composition unit is the "floor", it is considered that the operation of partially segmenting by the "floor" and the operation of integrating the parts are occurring at the same time. It seems that a precise composition method can be extracted.

Current authentication methods on the Web have serious weaknesses. First, services heavily rely on the traditional password paradigm, which diminishes the end-users’ security and usability. Second, the lack of attribute-based authentication does not allow anonymity-preserving access to services. Third, users have multiple online accounts that often reflect distinct identity aspects. This makes proving combinations of identity attributes hard on the users. In this paper, we address these weaknesses by proposing a privacy-preserving architecture for device-centric and attributebased authentication based on: 1) the seamless integration between usable/strong device-centric authentication methods and federated login solutions; 2) the separation of the concerns for Authorization, Authentication, Behavioral Authentication and Identification to facilitate incremental deployability, wide adoption and compliance with NIST assurance levels; and 3) a novel centralized component that allows end-users to perform identity profile and consent management, to prove combinations of fragmented identity aspects, and to perform account recovery in case of device loss. To the best of our knowledge, this is the first effort towards fusing the aforementioned techniques under an integrated architecture. This architecture effectively deems the password paradigm obsolete with minimal modification on the service provider’s software stack.

In this White Paper, we discuss the current state of microbial cancer therapy. This paper resulted from a meeting (‘Microbial Based Cancer Therapy’) at the US National Cancer Institute in the summer of 2017. Here, we define ‘Microbial Therapy’ to include both oncolytic viral therapy and bacterial anticancer therapy. Both of these fields exploit tumor-specific infectious microbes to treat cancer, have similar mechanisms of action, and are facing similar challenges to commercialization. We designed this paper to nucleate this growing field of microbial therapeutics and increase interactions between researchers in it and related fields. The authors of this paper include many primary researchers in this field. In this paper, we discuss the potential, status and opportunities for microbial therapy as well as strategies attempted to date and important questions that need to be addressed. The main areas that we think will have the greatest impact are immune stimulation, control of efficacy, control of delivery, and safety. There is much excitement about the potential of this field to treat currently intractable cancer. Much of the potential exists because these therapies utilize unique mechanisms of action, difficult to achieve with other biological or small molecule drugs. By better understanding and controlling these mechanisms, we will create new therapies that will become integral components of cancer care.

The authentication and authorization process is a critical factor in Wi-Fi enterprise networks, being the mechanism used to give access to the network resources. The general Wi-Fi enterprise network security frameworks have a static structure, being based on user-name/password credentials and without offering a flexible granular access. Nowadays, smart-phones devices are becoming ubiquitous and these can be used as security elements due to their hardware/software capabilities. Smart-phones have the capability to execute complex cryptographic operations and have the hardware peripherals, which allow authenticating the user. In this paper, we propose a smart-phone centric authentication and authorization solution which employs a bootstrap security protocols to provision temporary credentials for a WPA2 Enterprise protected Wi-Fi network.

In nature, the formation of iron sulfide solids is mainly attributed to reductions of sulfate and ferric minerals by microorganisms such asDesulfovibrio vulgaris.

It was hypothesized that auditory training would allow bimodal patients to combine in a better manner the low-frequency acoustic information provided by a hearing aid with the electric information provided by a cochlear implant, thus maximizing the benefit of combining acoustic (A) and electric (E) stimulation (EAS). Performance in quiet or in the presence of a multitalker babble at +5 dB signal to noise ratio was evaluated in seven bimodal patients before and after auditory training. The performance measures comprised identification of vowels and consonants, consonant-nucleus-consonant words, sentences, voice gender, and emotion. Baseline performance was evaluated in the A-alone, E-alone, and combined EAS conditions once per week for 3 weeks. A phonetic-contrast training protocol was used to facilitate speech perceptual learning. Patients trained at home 1 hour a day, 5 days a week, for 4 weeks with both their cochlear implant and hearing aid devices on. Performance was remeasured after the 4 weeks of training and 1 month after training stopped. After training, there was significant improvement in vowel, consonant, and consonant-nucleus-consonant word identification in the E and EAS conditions. The magnitude of improvement in the E condition was equivalent to that in the EAS condition. The improved performance was largely retained 1 month after training stopped. Auditory training, in the form administered in this study, can improve bimodal patients' overall speech understanding by improving E-alone performance.

Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM) to show an average diameter of about 140 nm. PtTFPP showed higher quantum efficiency in micellar solution than in tetrahydrofuran (THF) and dichloromethane (CH2Cl2). PtTFPP in micelles also exhibited higher photostability than that of PtTFPP suspended in water. PtTFPP in micelles exhibited good oxygen sensitivity and response time. This study provided an efficient approach to enable the application of hydrophobic oxygen sensors in a biological environment.

A wireless sensor node using vibration-driven MEMS electret generator has been prototyped. With the aid of high aspect-ratio nonlinear parylene springs and high-performance electret material CYTOP, 3.4μW power outoput was obtained in low-frequency quasi-environmental vibration. By combining the present energy harvester with power management circuit, low-power consumption CPU, and RF IC, temperature data was successfully transferred via 2.4GHz RF with an interval of 80.6s.

An autonomous wireless sensor node using MEMS electret energy harvester has been prorotyped. With hybrid high-aspect ratio parylene springs and high-performance electret material based on perfluoro polymer CYTOP, more than 3μW output power can be generated in a broad range vibration frequency of 26-40Hz at 1.4G. By using a power management circuit, low-power-consumption CPU, and RF IC, we can also successfully drive the wireless sensor node with an interval of 80.6s and transmit temperature data intermittently.