Nebraska Wesleyan University

ABSTRACT Christian nationalism and Christofascism theorists have surrendered the discursive floor to their empiricist critics. A flurry of recent research has asserted that critical paradigms within the sociology of religion are ideologically committed and empirically invalid. In this reply to Jesse Smith's “Old Wine in New Wineskins” (2024), I contend several things: (1) Christian nationalism and Christofascism research is based in empirical validity, (2) claims of “conceptual slippage” are irrelevant given the sociopolitical context, (3) rejection of the critical perspective reifies the unjust power structure through a normative appeal to rational‐legal scientific authority, and (4) critical epistemology in the sociology of religion remains a crucial tool in combating authoritarian slippage. It is my hope that this reply sparks further reflection and debate on the role of sociology and the nature of sociological praxis.

Promoting the success and retention of novice nursing students requires a better understanding of how self-regulated and strategic learning approaches impact academic performance. The purpose of this correlational study was to determine if there was a predictive relationship between the results of a self-regulated learning assessment and final grades in a foundational nursing course. The Learning and Study Strategies Inventory (LASSI) was used to collect data from a convenience sample of 75 students enrolled in an entry-level nursing course across 4 prelicensure programs. Scores were analyzed alongside demographic data and numeric grades at the end of the semester. Results demonstrated the significant predictive abilities of LASSI scores related to Anxiety, Concentration, Information Processing, Motivation, and Test Strategies. Additionally, non-native English speakers experienced significantly lower course grades. Nurse educators can improve student performance in an introductory course by teaching and modeling self-regulated and strategic learning practices.

The below documentation is an analysis of online integrative based supervision ideas with multicultural considerations. Various interventions with supervisees, which are aimed for supervisee reflective growth and client beneficence, are also discussed. Following Integrated Supervision Framework (ISF) description, a case vignette introducing reflective and inclusive online strategies is described. Future issues potentially affecting consideration of online supervision will also be described.

<div>Abstract<p>Mantle cell lymphoma (MCL) has one of the worst clinical outcomes among the B-cell lymphomas, with a median survival of only 3 to 4 years. Therefore, a better understanding of the underlying mechanisms that regulate MCL proliferation/survival is needed to develop an effective therapy. Because sonic hedgehog (Shh)-GLI signaling has been shown to be important in the proliferation and survival of several cancers, and no such information is available for MCL, this study was undertaken. Our results show that the molecules associated with Shh-GLI signaling, such as PTCH and SMO receptors, and GLI1 and GLI2 target transcription factors were expressed in the human MCL cell lines and primary MCL cells from patients. Perturbation of this signaling in the presence of exogenous Shh/cyclopamine significantly (<i>P</i> < 0.001) influenced the proliferation of JVM2 MCL cells. Furthermore, down-regulation of GLI transcription factors using antisense oligonucleotides not only resulted in significantly (<i>P</i> < 0.001) decreased proliferation of the MCL cells but also significantly (<i>P</i> < 0.05) increased their susceptibility to chemotherapeutic drug, doxorubicin. Also, down-regulation of GLI decreased cyclin D1 and BCL2 transcript levels, which suggests that these key molecules might be regulated by GLI in MCL. Thus, our results indicate a significant role for Shh-GLI signaling in the proliferation of MCL, and molecular targeting of GLI is a potential therapeutic approach to improve the treatment for MCL. [Mol Cancer Ther 2008;7(6):1450–60]</p></div>

Beta-adrenergic agonists (β-AAs) are widely used supplements in beef and pork production to improve feed efficiency and increase lean muscle mass, yet little is known about the molecular mechanism by which β-AAs achieve this outcome. Our objective was to identify the influence of ractopamine HCl and zilpaterol HCl on mitochondrial respiratory activity in muscle satellite cells isolated from crossbred beef steers (N = 5), crossbred barrows (N = 2), Yorkshire-cross gilts (N = 3), and commercial weather lambs (N = 5). Real-time measurements of oxygen consumption rates (OCRs) were recorded using extracellular flux analyses with a Seahorse XFe24 analyzer. After basal OCR measurements were recorded, zilpaterol HCl, ractopamine HCl, or no β-AA was injected into the assay plate in three technical replicates for each cell isolate. Then, oligomycin, carbonyl cyanide-p-trifluoromethoxyphenylhydrazone, and rotenone were injected into the assay plate sequentially, each inducing a different cellular state. This allowed for the measurement of OCR at these states and for the calculation of the following measures of mitochondrial function: basal respiration, non-mitochondrial respiration, maximal respiration, proton leak, adenosine triphosphate (ATP)-linked respiration, and spare respiratory capacity. Incubation of bovine cells with either zilpaterol HCl or ractopamine HCl increased maximal respiration (P = 0.046) and spare respiratory capacity (P = 0.035) compared with non-supplemented counterparts. No difference (P > 0.05) was observed between zilpaterol HCl and ractopamine HCl for maximal respiration and spare respiratory capacity in bovine cell isolates. No measures of mitochondrial function (basal respiration, non-mitochondrial respiration, maximal respiration, proton leak, ATP-linked respiration, and spare respiratory capacity) were altered by β-AA treatment in ovine or porcine cells. These findings indicate that β-AAs in cattle may improve the efficiency of oxidative metabolism in muscle satellite cells by modifying mitochondrial respiratory activity. The lack of response by ovine and porcine cells to β-AA incubation also demonstrates differing physiological responses to β-AA across species, which helps to explain the variation in its effectiveness as a growth supplement.

Recognized as one of the most beautiful experiments of all time, the oil drop experiment performed by Robert Millikan and his graduate students (primarily Harvey Fletcher) is a standard in the repertoire of experiments performed by undergraduate physics students. However, “as a teaching lab it does not enjoy a good reputation for three reasons: eyestrain, tedium, and poor, unconvincing results.” Several have attempted to make this experiment more student-friendly by improving the optics and replacing the stopwatch with a computer, replacing the eye with a video camera, and utilizing video analysis tools. Currently available versions of the oil drop apparatus for high school and college students have incorporated a number of these features. On the other hand, others are ready to replace the experiment with interactive computer-based simulations. There is another alternative: Have students analyze pre-recorded videos of the Millikan experiment. Besides the “Millikan Movies” produced at the California State University at Chico, the collection “Physics: CINEMA CLASSICS” (“PCC”) contains the essential nuggets from a Physical Science Study Committee (PSSC) educational film made in 1959 sufficient to compute the elementary electric charge.

While some of the most elegant applications of topological insulators, such as the quantum anomalous Hall effect, require the preservation of Dirac surface states in the presence of time-reversal symmetry breaking, other phenomena such as spin-charge conversion rather rely on the ability for these surface states to imprint their spin texture on adjacent magnetic layers. In this Rapid Communication, we investigate the spin-momentum locking of the surface states of a wide range of monolayer transition metals ($3d\ensuremath{-}\mathrm{TM}$) deposited on top of ${\mathrm{Bi}}_{2}{\mathrm{Se}}_{3}$ topological insulators using first-principles calculations. We find an anticorrelation between the magnetic moment of the $3d\ensuremath{-}\mathrm{TM}$ and the magnitude of the spin-momentum locking induced by the Dirac surface states. While the magnetic moment is large in the first half of the $3d$ series, following Hund's rule, the spin-momentum locking is maximum in the second half of the series. We explain this trend as arising from a compromise between intra-atomic magnetic exchange and covalent bonding between the $3d\ensuremath{-}\mathrm{TM}$ overlayer and the Dirac surface states. As a result, while Cr and Mn overlayers can be used successfully for the observation of the quantum anomalous Hall effect or the realization of axion insulators, Co and Ni are substantially more efficient for spin-charge conversion effects, e.g., spin-orbit torque and charge pumping.