Princip (Czechia)

The injection moulding technique provides a minimally invasive approach offering a predictable and simplied treatment protocol to achieve functional and aesthetic outcome using the highly lled owable composite resin. Furthermore, this approach can be viewed as a more cost-effective alternative. The injection moulding technique is a minimal invasive procedure to treat clinical situations with challenging aesthetic demands, recreate complex morphologies, re-establish the vertical occlusal dimension. In this paper presentation, case report of a 25 year old female will be presented which was diagnosed with discoloration and incisal edge chipping, for which direct composite veneers were planned using injection moulding technique. Transparent silicone index was created from wax up models and high lled owable composite application was performed through the holes created over the transparent silicone index. This efcient method resulted in optimal, aesthetically pleasing outcomes, leading to high patient and dentist satisfaction. However, additional follow-ups are essential to thoroughly assess the clinical longevity of the restoration.

As mudanças na sociedade e o uso crescente de tecnologias digitais no cotidiano dos estudantes têm motivado reflexões sobre o papel dessas ferramentas na educação. Este ensaio tem como objetivo discutir os desafios e as potencialidades do uso de tecnologias digitais no processo de ensino-aprendizagem, com foco na formação em saúde e na adoção de metodologias ativas. Trata-se de um estudo teórico-reflexivo, baseado em revisão narrativa de literatura nacional e internacional. A análise contempla estratégias como gamificação, realidade aumentada e inteligência artificial, considerando seu potencial para promover a autonomia dos estudantes, estimular o pensamento crítico e possibilitar percursos de aprendizagem personalizados. Também são discutidas dificuldades como a falta de formação docente, as limitações na infraestrutura das instituições e os riscos do uso padronizado das tecnologias. O texto apresenta abordagens pedagógicas atuais que buscam integrar inovação com práticas mais inclusivas e participativas. O referencial teórico está fundamentado em autores como Moran (2015; 2018), Felcher, Blanco e Folmer (2022), Silva e Couto (2024), Camacho e Souza (2021) e Sá et al. (2023), cujas contribuições permitem aprofundar a análise sobre o papel das tecnologias digitais na formação em saúde. Conclui-se que a integração crítica e criativa das tecnologias pode contribuir para ambientes educacionais mais dinâmicos e conectados com as necessidades do mundo atual, desde que articulada a propostas pedagógicas intencionais e comprometidas com a diversidade e a qualidade do ensino.

Background: Shoulder dysfunction is a common musculoskeletal condition affecting daily functional activities, causing pain, reduced range of motion (ROM), and diminished strength. Theraband training and closed kinetic chain exercises are widely used rehabilitation strategies, but their comparative effectiveness remains unclear. This study aims to evaluate and compare the impact of these two exercise modalities on pain, ROM, muscle strength, and functional outcomes in individuals with shoulder dysfunction. Methods: A randomized controlled trial was conducted involving 30 participants with shoulder dysfunction, divided equally into two groups: PNF training with Theraband (n=15) and closed kinetic chain (n=15). Baseline and post-intervention assessments were conducted, including pain levels using the Visual Analog Scale (VAS), shoulder ROM across flexion, extension, abduction, adduction, internal rotation, and external rotation, muscle strength (measured in kg), and functional status using the Shoulder Pain and Disability Index (SPADI). Data were analyzed statistically to compare pre- and post-intervention results. Results: Both exercise groups demonstrated significant improvements in pain, ROM, strength, and functional status post-intervention (p<0.05). However, the Closed kinetic chain group exhibited superior outcomes in ROM and muscle strength compared to the Open kinetic chain group (p<0.001). Pain reduction and functional improvements were comparable between the groups, indicating the effectiveness of both modalities in addressing shoulder dysfunction. Conclusion: While both PNF training with Theraband and Closed kinetic chain exercises are effective in managing shoulder dysfunction, closed kinetic chain exercises demonstrated superior improvements in ROM and muscle strength. These findings suggest that closed kinetic chain exercises should be prioritized in rehabilitation protocols for patients with shoulder dysfunction.

Background: The World Health Organization (WHO) in 2020 has estimated the nursing shortage in India.1 The objective of the study was to assess the nurse’sperceptions towards digital support to manage work related stress. A qualitative descriptive is undertaken as a pilot project to explore nurses experience of using digital support to manage work related stress at Dr Vitthalrao Vikhe Patil, Pravara Rural Hospital, Loni (Bk), large tertiary care facility in Western India. It is part of a larger project “Nurses life world”, a research cooperation with Lund University, Dalarna University and Skovde University Sweden. Methods: Thirty nurses were selected via purposive sampling. ATLAS. it7 software tool for organization and analysis of qualitative data was used to analyze the verbatim transcript. Data was collected through open-ended interview guide questions and face-to-face individual interviews. Ethical considerations were applied to all stages of the study. The collected data was analyzed according to the content analysis method suggested by Graneheim and Lundman. Results: The study resulted in six themes, six main categories and thirty five sub-categories. The themes includes:positive experience to digital support, implication features of digital stress apps, emerging innovative technology opportunities, difficulties and challenges of digit apps, future perspectives and seeking facilitators. Conclusion: The present study shows the digital support is useful for the nurses to cope with work related stress. The study provides insight to develop appropriate stress management digital apps for nurses in the working environment to cope with occupational stress.

Background-Athletes are always looking for ways to get better at what they do and get hurt less frequently. Movement efficiency and total physical capability are influenced by flexibility and agility, which are essential elements of athletic success. Pilates mat movements have a reputation for enhancing body awareness, flexibility, and core strength. Despite its growing popularity, the impact of incorporating Pilates into athletes' training routines, particularly concerning flexibility and agility, remains largely unexplored. Objective-The purpose of this study was to evaluate the agility and flexibility of athletes who included Pilates mat movements in their training regimen to a control group who continued with their regular training regimen. Methods-Two groups, Group A (experimental) and Group B (control), each with fifteen participants, were randomly selected from among the thirty participants. Group B adhered to their regular training program without making any alterations, Group A engaged in Pilates mat exercises three days per week for six weeks, following informed consent obtained from each participant prior to the intervention. Agility and flexibility were assessed using the 4 x 10-meter shuttle run test and the sit and reach test before and after a six-week intervention period. Results and Conclusion-Compared to Group B, Group A showed noticeably greater flexibility and agility after the intervention. With a standard deviation of improvement of 2.90, the experimental group (Group A) demonstrated an average improvement in the sit and reach test score from 21.5 to 27.7. Group B, the control group, saw very little improvement; mean scores varied greatly, going from 22.18 to 22.20. Group A's mean time in the 4 x 10-meter shuttle run test increased from 23.3 to 21, while Group B's mean time only marginally improved from 21.53 to 22.07. These results imply that adding Pilates mat exercises to athletes' training regimens can increase their flexibility and agility, which may help them perform better on the field and avoid injuries. To confirm these results and investigate the long-term advantages of Pilates for athletes, more studies with bigger sample numbers and longer intervention times are necessary.

The Sounds of Life: How Digital Technology Is Bringing Us Closer to the Worlds of Animals and Plants by Karen Bakker (2022) 368 pp., Princeton University Press, Princeton, USA. ISBN 978-0-691-20628-8 (hbk), USD 33.00. - Volume 57 Issue 6

This paper discusses machine learning techniques in biotechnology for analyzing protein structure and extracting features based on Natural language processing techniques in Artificial intelligence. Modern biotechnology is providing breakthroughs in products and technologies to address debilitating and rare diseases, thereby contributing to global healing. The convergence of artificial intelligence and biotechnology has emerged as a transformative force in the life sciences, enabling researchers to leverage vast amounts of data and derive meaningful insights. In the context of environmental biotechnology, real-time data processing facilitated by natural language processing is becoming increasingly crucial. The paper explains details about Protein structure is a fascinating and complex topic, essential for understanding how proteins function and different AI techniques for extracting key features associated with specific protein structures. This paper also talks about ethical Implications of AI in Biotechnology Data Privacy and Security Issues and Addressing Bias in Machine Learning Models

Abstract Background Acute lymphoblastic leukemia (ALL) is the most common neoplasm in childhood, characterized by rapid production of abnormal lymphoid cells. The instituted chemotherapy for these patients can promote a serious imbalance in oral microbiota. Methods A pediatric prospective study using a control group (without ALL) and ALL patients in two moments of treatment (pre-induction and consolidation) was executed. Clinical and laboratorial data was collected. In addition, DNA from saliva samples of patients was extracted for 16S rRNA sequencing. Results Clinical data showed higher degree of oral mucositis in the consolidation phase. Analysis of alpha biodiversity (observed taxa) showed a significant decrease in bacterial richness in patients in the consolidation phase. Network analysis showed that the key taxa in the consolidation phase were Neisseria flavescens, Prevotella melaninogenica and Porphyromonas. Conclusions The results showed that LLA treatment can lead to significant changes in the composition of the oral microbiota, with reduced bacterial diversity and increased degree of oral mucositis.

Objetivo: descrever a percepção dos cuidadores frente a dor pós-operatória pediátrica e cuidados de enfermagem. Método: estudo descritivo, realizado na Unidade de Pediatria de um Hospital Universitário no Paraná com dados coletados mediante formulário sociodemográfico e questionário de Dor de MCGill-Melzack adaptado e análise a partir de estatística descritiva. Resultados: participaram do estudo 24 cuidadores de crianças submetidas a intervenções cirúrgicas, predominantemente, mulheres (22), preponderando as crianças do sexo masculino. Os resultados apresentaram maior utilização de dipirona como analgesia (50%), tendo a maioria dos cuidadores descrito a dor como breve (33,3%). O principal comportamento de dor relatado foi choro (35%). De forma geral, os cuidadores classificaram a assistência de enfermagem como muito boa ou excelente. Conclusão: o profissional de enfermagem, reconhece a dor como um evento importante e presta assistência. O estudo incita a necessidade de padronização de instrumentos de avaliação e manejo da dor pediátrica pós-operatória.