Ukrainian Medical Stomatological Academy

Difficult tooth eruption or pericoronitis is a very common disorder, which seems to be the most frequent reason of extraction of third molars. It is accompanied by an inflammation of the soft tissues. According to the literature, the microflora of pericoronal pouch mainly consists of hemolytic Streptococcus and anaerobic species of Prevotella and Veillonella genera. However, changes in population immunity and development of diagnostic methods led to some changes of microbiota composition. Moreover, there are no case reports which show presence of Streptococcus pluranimalium in the human oral cavity and its ability to cause a pathology of the maxillo-facial region. This report describes the first case of identification S. pluranimalium as a pathogen among microorganisms of the oral cavity and proves its main role in development of acute purulent pericoronitis.

Aim: The purpose of the work was study of the influence of genetic and environmental factors on the formation of classic smile parameters. Materials and Methods: Research was conducted on 12 people (6 pairs of (MZ) twins): 4 pairs of females and 2 pairs of males. The age of the patients was 17-28 years. Results: In (MZ) twins, the criteria for an ideal smile coincide in 51.6% of cases, do not coincide in 26.6% of cases, there are no criteria in 21.8% of cases. Genetic factors have a significant influence on the morphological features of the teeth, because more than 50% of the parameters of an ideal smile in (MZ) twins are coincided. Conclusions: Signs of external similarity in (MZ) twins, taking into account such morphological characteristics as the set of the eyes, the shape of the nose, lips and teeth are confirmed by photo documentation and biometric research methods. However, the ratio between lips, teeth and gums when forming a smile in (MZ) twins is the same in 51.6% of cases. Based on the results of this study, we cannot confirm the primary role of genetics in dental features such as the ideal smile criteria. Environmental factors (nature of nutrition, bad habits, sucking, tooth extraction, sleeping on the stomach, etc.) and traumas have a significant influence on the features of dental smile parameters.

Wonorejo Village is located in Polokarto District, Sukoharjo Regency, Central Java Province, which shows a high commitment to the welfare of the elderly. One of the diseases that is often suffered by the elderly is knee osteoarthritis. Objective: to reduce complaints that arise in knee osteoarthritis conditions such as pain, stiffness, and increase the ability of daily activities. Method: An educational approach based on pre-test and post-test to measure the increase in participants' knowledge before and after the activity. Results: Pre-test and post-test evaluations showed a significant increase in the understanding of elderly participants after counseling and demonstration activities related to knee osteoarthritis. Conclusion: counseling accompanied by demonstrations of simple exercises has proven effective in increasing the understanding of the elderly about osteoarthritis and how to handle it independently

РОЛЬ STEAM-ОСВІТИ У ФОРМУВАННІ КРЕАТИВНОСТІ Й ІННОВАЦІЙНОГО МИСЛЕННЯ ЗДОБУВАЧІВ ОСВІТИАнотація.Цю статтю присвячено дослідженню ролі STEAM-освіти у формуванні креативності й інноваційного мислення здобувачів освіти

.

Arterial hypertension is becoming increasingly common among diseases of the cardiovascular system. The work aimed to analyze blood pressure control in patients diagnosed with arterial hypertension. Fifty physicians and 1020 patients (under 56 years of age) participated in the study. Regular use of medications was observed in 92% of the patients, and the systolic blood pressure level was 167 mm Hg. More frequent use of renin-angiotensin system blockers compared with diuretics and calcium antagoni

Комбинация метформина (МФ) (2 г в сутки) и пиоглитазона (ПГ) (30 мг в сутки) у 57 больных ишемической болезнью сердца (ИБС) и сахарным диабетом 2-го типа (СД-2) снижает показатели хронического воспаления (ХВ) низкой интенсивности: уровень фактора некроза опухоли альфа в крови — в 5 раз через 6 месяцев, интерлейкина-6 — в четыре раза соответственно по сравнению с исходным уровнем. Эта комбинация является безопасной, оказывает позитивный клинический эффект в отношении ИБС и более эффективно нормализует уровень гликированного гемоглобина у больных по сравнению с комбинацией МФ и препарата сульфонилмочевины. Поскольку ХВ является фактором, инициирующим развитие атеросклероза, ИБС, артериальной гипертензии и СД-2, комбинацию МФ и ПГ следует считать эффективным и безопасным средством профилактики и лечения этих заболеваний, что подтверждается анализом современной научной литературы.

The study of the mechanisms of the effect of various food additives on the human and animal organism is one of the most pressing problems today. The work of physicians, toxicologists, physiologists is aimed at studying the mechanisms of the toxic effect of food additives, as well as studying compensatory-adaptive reactions in response to their ingestion. Monosodium glutamate (E621) is widely used in marketing as a flavor enhancer and is added to many processed foods. Today, about 50% of store products contain this additive, while the average daily human consumption in industrialized European countries is approximately 0.3-1.0 g. The purpose of this work is to analyze the literature data on the effect of monosodium glutamate on various organs and systems of the human body. The research used the bibliosemantic method of analyzing scientific publications. The article assesses 40 literary sources. Special attention is paid to the sources for the last 5 years (2016-2021). This review of the scientific literature proves the importance of further study of food additives and their effect for the development of a scientifically based strategy for increasing the tolerance of humans and animals to xenobiotics by activating genetically fixed mechanisms, as well as by creating new perfect adaptogens.