University of Hyderabad

Abstract In this research, we have examined a food web model to explore the impact of fear effects and harvesting of apex predators on dynamic behaviors. We have utilized Caputo and Caputo–Fabrizio (C–F) fractional derivatives to analyze the model's complexity and dynamics. We have investigated the existence and uniqueness of solutions through fixed point theory and evaluated the system's stability utilizing the Ulam–Hyers (U–H) criterion. We also employed numerical schemes utilizing the Caputo and C–F fractional operators to deepen our understanding of the food web model. The system analysis demonstrates chaotic dynamics, attractors, and periodic windows. Additionally, we have investigated the numerical solution using matlab. We have examined the time series graph while varying the values of the parameters and provided better, more intricate information about the solution of the food web model. We have analyzed the Hopf bifurcation by varying different parameters. Significantly, we have analyzed that the fear effect can mitigate variations in population density, aiding in stabilizing the system.

ABSTRACT The phosphatidylinositol 3‐phosphate 5‐kinase (PIKfyve), is a key enzyme in the phosphoinositide signaling pathway, which plays a crucial role in the development of various cancers and viral diseases. The essential role of small molecules that inhibit this enzyme is limited, which further complicates the design of effective and selective inhibitors. In this study, we employed a BREED‐based de novo ligand design strategy after the detection of a binding pocket in PIKfyve. The BREED‐based molecules were subjected to pharmacokinetic and docking studies. From molecular dynamics (MD) simulations, the hit molecules were observed to exhibit stable behavior in complex with the protein and retain favorable interactions at the binding site. These molecules were also assessed on the synthesizability scale, through reaction‐based enumeration, to determine their ease of synthesis. Overall, the study undertaken describes a de novo hybridization approach that automates the inhibitor design process to reduce the time for producing reliable results when there is limited information about inhibitors in the literature. The selected candidate molecules reveal molecular insights into the inhibition mechanism of PIKfyve.

The agriculture sector plays a pivotal role in global economies, and optimizing its perishable food supply chain (PFSC) is vital to ensuring food security and transparency. The purpose of the study is to develop a blockchain-based smart contract to secure and provide transparency about perishable goods in the PFSC while delivering the goods between the stakeholders, such as farmers, mandis, and wholesalers. The study enhances collaboration between stakeholders by implementing smart contracts. The delivery status and the transactions have been safely recorded and verified by the stakeholder in the PFSC to ensure data integrity all the way through. The blockchain application has reduced fraud and streamlined the flow of goods and information. Moreover, this study emphasizes providing farmers with a straightforward route to the market to empower them. The benefits for the stakeholders are optimizing inventory control and developing appropriate decision-making skills. A three-echelon PFSC can become more resilient and is able to meet changing market demands by implementing blockchain-based smart contracts. Finally, the study employs blockchain technology to establish a decentralized and efficient PFSC, confirming a tamper-resistant system and enhancing stakeholder trust and collaboration.

Two-dimensional materials are a fertile ground for exploring quantum geometric phenomena, with Berry curvature and its first moment, the Berry curvature dipole, playing a central role in their electronic response. These geometric properties influence electronic transport and result in the anomalous and nonlinear Hall effects, and are typically controlled using static electric fields or strain. However, the possibility of modulating quantum geometric quantities in real-time remains unexplored. Here, we demonstrate the dynamic modulation of Berry curvature and its moments, as well as the generation of a pseudo-electric field and their coupling. By placing heterostructures on a membrane, we introduce oscillatory strain together with an in-plane AC electric field and measure Hall signals that are modulated at linear combinations of the frequencies of strain and electric field. We also present direct experimental and theoretical evidence for coupling between pseudo-electric field and quantum geometry that results in an unusual dynamic strain-induced Hall response. This approach opens up a new pathway for controlling quantum geometry on demand, moving beyond conventional static perturbations. The coupling of the pseudo-electric field with Berry curvature provides a framework for external electric field-free anomalous Hall response and opens new avenues for probing the topological properties.

Charge transport in metal halide perovskites is strongly limited by electron–phonon coupling (EPC) and trap-assisted recombination, which together hinder carrier mobility and device efficiency. Therefore, precise control of EPC strength is crucial for realizing high-performance optoelectronic devices, such as photodetectors. Here, we demonstrate a strategy to overcome these limitations by suppressing Fröhlich electron–phonon coupling in CsPbBr3 nanocrystals through strategic Ag-doping. Low temperature photoluminescence data reveal a dramatic suppression of the Fröhlich interaction, with the EPC strength narrowing from 85.1 ± 8.2 to 45.3 ± 6.1 meV, accompanied by a reduced activation energy upon Ag incorporation. This suppression of phonon-mediated dissipation is further validated by ultrafast transient absorption studies, which reveals significantly prolonged ground-state bleach recovery and extended carrier lifetimes. Consequently, Ag-doped photodetectors exhibit a record detectivity of ∼8.4 × 1013 Jones, an on/off ratio of ∼107, and a fourfold enhancement in the responsivity (0.64 A/W). The near-unity photocurrent behavior with intensity (exponent of 0.98), along with emission behavior, confirms Ag-doping passivates defects and improves carrier extraction. These results establish a strong correlation between lattice engineering and macroscopic device physics, offering a scalable route to high-performance, phonon-managed perovskite optoelectronics.

Purpose This research delves into the complex relationship between foreign direct investment (FDI) inflows and domestic investment in India, data spanning from 1st Quarter (Q1) of 1997 to 4th Quarter (Q4) of 2019. In other words, the aim of this paper is to examine whether FDI has a crowding-in or crowding-out effect on domestic investment in India using a multivariate model wherein economic growth, trade openness, and financial development are included as additional variables. Design/methodology/approach Employing estimation techniques with a focus on structural breaks, we utilize both the Gregory–Hansen cointegration test and the autoregressive distributed lag (ARDL) bounds testing approach to cointegration. Additionally, the stationarity properties of the variables are assessed employing the Zivot-Andrews unit root test. Findings This study confirms the existence of a long-run relationship between FDI inflows and domestic investment in India. Notably, the results indicate a significant crowding-out effect of FDI on domestic investment. The results suggest that increased foreign investment may potentially displace or hinder domestic investment initiatives. Further, the study reveals that factors such as economic growth, financial development and trade openness have a positive and stimulating impact on domestic investment in both the long run and short run. Originality/value Based on these findings, we conclude that because of the significant crowding-out impact of FDI on domestic investment, policymakers need to be cautious while formulating their sustainable growth-stimulating policy for India, focusing on FDI. They should not simply believe that inflows of FDI always help increase the ability to produce in the economy; quality FDI should especially be encouraged. It also highlights that a significant positive effect of economic growth, financial development, and trade openness on domestic investment indicates the importance of fostering an environment conducive to domestic investment, taking into account various economic growth drivers.