Wesley Guild Hospital

Abstract Background: Anxiety is a psychological disorder in adolescents that usually affects adolescents’ social and academic functioning. This study determined the pattern of anxiety among secondary school adolescents in Ilesa, Nigeria. Materials and Methods: A descriptive cross-sectional study was conducted among 302 secondary school adolescents aged 10–19 years in Ilesa, Nigeria. They were chosen with the multistage sampling method and screened for anxiety with generalised anxiety disorder-7 according to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition. The socio-demographic characteristics of the adolescents were determined with the Oyedeji classification. Results: The prevalence of anxiety among adolescents in this study was 37.7% and about half of the early adolescents (10–13 years) had anxiety while about a quarter of middle adolescents (14–16 years) had anxiety. Anxiety was statistically significantly higher among early adolescents than middle and late adolescents (χ2 = 14.205, P = 0.013). More than half (53.1%) of the males had anxiety while a little above a quarter of the females had anxiety. The prevalence of anxiety was statistically significantly higher in males than females (χ2 = 9.782, P = 0.001). All adolescents with single parents had anxiety while about a third of those whose parents were married had anxiety. The prevalence of anxiety was statistically significantly higher among adolescents with single parents (χ2 = 34.546, P = 0.001). Conclusion: The prevalence of anxiety is high among school adolescents and more in male adolescents as well as those with single parents. School health programmes will help for prompt diagnosis and support.

The birth of a child can be filled with joy. However, the transition into motherhood role can as well be stressful, especially for first-time mothers. Mothers often do not sleep well at night due to the demands of the baby. These results in poor sleep quality at night and increased day-time sleepiness. The aim of this study is to assess the sleep quality and postpartum depression among nursing mothers. This study was done using a cross-sectional study design. The respondents (191) were mothers attending postnatal clinic in WGH and IHU, OAUTHC. The questionnaires were designed using the following scales: Pittsburgh sleep quality index (PSQI) was used to assess the sleep quality and sleeping patterns and Edinburgh postpartum depression scale was used to assess for signs and symptoms of postpartum depression. The mean age of the respondents was 32.10 ± 5.812. Majority of the respondents, 38.2% age range was between 26 – 31 years. More than half of the respondents’ current postpartum period and age of baby was between 1 – 6 months (54.5%) while more than 12 months (9.4%). More than half of the respondents, 52.9% sex of the baby was male while 47.1% were females. 84.3% of the respondents were from monogamy family and 15.7% were from polygamy family. About(24.6%) of the respondents had low level of stress, 100 (52.4%) had moderate level of stress, 41 (21.5%) had high level of stress and 3 (1.6%) had very high level of stress. More than 104 (54.5%) of the respondents had no depression and 87 (45.5%) of the mothers attending immunization visit or postpartum care had possible depression. It was recommended that extended family members should be educated on how to provide care and support for new mothers to ease the burden they experience.

The correct association between Plasmodium falciparum parasite density and the cellular constituents of blood is not known in entirety in Nigerian children. Thus, we decided to study the association between cellular blood constituents and malaria parasite density in malaria infected children attending a Nigerian hospital. A study of all children diagnosed with malaria fever at the Pediatric out-patient clinic, Cedar Crest Hospital, Abuja, Nigeria, was conducted. Packed cell volume, white blood cells with differentials and platelet counts and malaria parasite densities obtained from blood samples were studied. Malaria parasite densities more than 2 pluses were classified as significant parasitemia and 1 plus as non-significant. Information obtained was recorded and analysed with SPSS 22 software. A total 143 children (74 boys and 69 girls) diagnosed with malaria of ages between 5 months to 17 years (mean 5.24 ±4.60) were studied. The majority of 141 (98.6%) had non-significant P. falciparum parasitemia, while 2 (2.4%) had significant parasitemia. Of the 143 children with malaria, 116 (81.1%) had a normal leucocyte count. All children with significant parasitemia had a normal leucocyte count. Of the 143 children, 11 (7.7%) had anemia and 10 (7.0%) thrombocytopenia. Anemia, monocytosis and thrombocytopenia were significantly associated with significant malaria parasitemia (p<0.05). Mean platelet counts was significantly less amongst those with significant parasitemia (p<0.01). All patients with significant malaria parasitemia had normal leucocyte count. Significant malaria parasitemia is significantly associated with anemia, thrombocytopenia and monocytosis. Blood film appearances showing these changes are suggestive of significant malaria parasitemia.

Monkeypox is now a disease of global public health concern, making it cut across boundaries into different countries, continents and spread worldwide. However, it originated in the Democratic Republic of Congo as a human pathogen in 1970, with the first case reported in Nigeria in 1971. The World Health Organization recently declared Nigeria the country with the highest burden of monkeypox-confirmed cases and deaths in Africa for the current outbreak. This study aimed to identify forms, challenges, strengths, and ways to further strengthen the surveillance system of monkeypox in Nigeria. We conducted a rapid narrative review of articles published in English on monkeypox between January 2018 and October 2022. Google Scholar and PubMed were searched with the following terms: "Monkeypox", "Surveillance system", "Strengthening", "Challenges" "Nigeria" and relevant publications were reviewed. The forms of surveillance systems in Nigeria include Indicator-based and Event-based surveillance, contact tracing, laboratory-based surveillance, sero-surveillance, and mortality surveillance. Shortage of highly skilled staff in public health interventions, insufficient testing capacities, power instability, poor healthcare systems and stigmatization from communities with misinformation, and co-epidemic surveillance burden in Nigeria are some of the challenges contributing to weak surveillance in the country. The Nigerian governments must focus on investing in surveillance systems and bolster preparedness to stem the rapid spread of infectious diseases. Strengthening the surveillance system in the country as a response intervention for monkeypox is no longer a matter of option in Nigeria but of necessity to prevent the forecasted effect the incidence portends.

Caregivers' burden and health-related quality-of-life (HRQoL) associated with Diabetes Mellitus (DM) are affected by several factors, including socio-demographic characteristics of the patients and their caregivers. Unfortunately, studies evaluating the influence of socio-demographic characteristics on caregivers and patients with DM in this environment are limited. This study therefore aimed at assessing the level of the burden imposed on the primary caregivers, the level of HRQoL of Individuals with Diabetes Mellitus (IDM) and the influence of socio-demographic characteristics on these variables among IDM attending the Family Medicine clinic of Wesley Guild Hospital, Ilesa, Osun State, Nigeria. Seventy-eight consenting IDM and their corresponding primary caregivers were recruited over 13-weeks in this hospital-based cross-sectional descriptive study. The Well-Being Questionnaire and Zarit Burden Interview were administered on IDM and their corresponding caregivers to assess HRQoL and burden of care. Data were analysed on SPSS 17 using descriptive statistics and Pearson chi-square test at p<0.05. Mean ages of respondents were 70.4±6.33 and 23.7±7.58 years for diabetics and caregivers, respectively. The majority of the diabetic respondents were females (61.5%), married (66.7%), and retired (64.1%). The majority of the caregivers were females (87.2%), petty traders/students (71.8%) and unmarried (87.2%). Over half (51.3%) of the diabetic respondents and their caregivers had 'good' HRQoL and 'high' caregivers' burden. The caregiver being a female, having primary education, being single and having a nuclear family relation of the IDM influenced good HRQoL, whereas being a low-income earner and an uneducated IDM influenced high caregivers' burden.

Epidural analgesia is widely used as an effective method of pain relief in labor. This study was therefore designed to investigate the awareness and level of utilization of obstetric analgesia in labour among pregnant women in Wesley Guild Hospital Ilesha, Nigeria. The descriptive study involving 110 pregnant women revealed that about half (41.8%) of the respondents had poor knowledge score, 37.3% had fair knowledge, while 20.9% had good knowledge score on obstetric epidural analgesia. Only 10.9% of the respondents had used epidural analgesia and 83.3% were satisfied with the use. There was a significant relationship between knowledge of respondents and the use of obstetric epidural analgesia. Moderate awareness, poor knowledge and low level of utilization of obstetric epidural analgesia were documented. There is a need for adequate awareness programs to enhance the knowledge of epidural analgesia and its utilization among pregnant women in order to reduce the excruciating labour pain.

Aims: This study investigates the hypoglycemic potential of Archachatina marginata haemolymph and its mechanism in streptozotocin -induced diabetic rats. Study Design: One factor experimental design. Place and Duration of Study: Department of Chemical Sciences, Joseph Ayo Babalola University, Ikeji Arakeji, Osun State, Nigeria between January to June, 2015. Methodology: The rats were set into four groups (n=5). Group 1 - Non-diabetic control (NDC), Group 2 - Diabetic Control (DC), Group 3 - Diabetic rats with 1 mL administration of snail Original Research Article Adeboye et al.; JPRI, 18(1): 1-8, 2017; Article no.JPRI.33786 2 haemolymph (DSS1), Group 4 - Diabetic rats with 2 mL snail haemolymph administration (DSS2). The blood glucose concentration of each rat was taken and thereafter, they were weighed and then administered with 55 mg/kg STZ in citrate buffer (pH 4.5) peritoneally non-diabetic control group (NDC). Rats with blood glucose level of 200 mg/dL and above were considered diabetic. Haemolymph of 1 mL and 2 mL were administered to rats in DSS1 and DSS2 respectively while DC received 2 mL distilled water for 14 consecutive days. Physiological orangs and blood samples were harvested for various analysis. Results: The A. marginata haemolymph significantly improved the plasma concentration of insulin and reduced plasma glucose level in a dose dependent manner P=.05. Conclusion: The A. marginata haemolymph has potential to exact hypoglycemic effect and improve the insulin concentration in streptozotocin induced diabetic rat. Keywords: Archachatina marginata; haemolymph; streptozocin diabetes rats.

Introduction:Optimal asthma control is a major aim of childhood asthma management. This study aimed to determine factors associated with suboptimal asthma control at the pediatric chest clinic of a resource-poor center.Methods:Over a 12-month study period, children aged 2–14 years with physician-diagnosed asthma attending the pediatric chest clinic of the Wesley Guild Hospital (WGH), Ilesa, Nigeria were consecutively recruited. Asthma control was assessed using childhood asthma control questionnaire. Partly and uncontrolled asthma was recorded as a suboptimal control. Relevant history and examinations findings were compared between children with good and suboptimal asthma control. Binary logistic regression analysis was used to determine the predictors of suboptimal asthma control.Results:A total of 106 children participated in the study with male:female ratio of 1.5:1, and majority (83.0%) had mild intermittent asthma. Suboptimal asthma control was observed in 19 (17.9%) of the children. Household smoke exposure, low socioeconomic class, unknown triggers, concomitant allergic rhinoconjunctivitis, and poor parental asthma knowledge, were significantly associated with suboptimal control (P < 0.05). Low socioeconomic class (odds ratio [OR] =6.231; 95% confidence interval [CI] =1.022–8.496; P = 0.005) and poor parental asthma knowledge (OR = 7.607; 95% CI = 1.011–10.481; P = 0.007) independently predict suboptimal control.Conclusion:Approximately, one in five asthmatic children attending the WGH pediatric chest clinic who participated in the study had suboptimal asthma control during the study. More comprehensive parental/child asthma education and provision of affordable asthma care services may help improve asthma control among the children.