ДИНАМИКА ЗАБОЛЕВАЕМОСТИ БОЛЕЗНЯМИ СИСТЕМЫ КРОВООБРАЩЕНИЯ ВЗРОСЛОГО НАСЕЛЕНИЯ РОССИЙСКОЙ ФЕДЕРАЦИИ В 2007-2019 ГГ.

Introduction. In the Russian Federation, diseases of the circulatory system are leading in the structure of the common incidence and mortality in the adult population, and since 2008, they have also been the leading causes of death among the employable age population. Reducing mortality among the employable age population and mortality from diseases of the circulatory system are the most important target indices of the national project “Healthcare”. Materials and methods. Life expectancy was calculated using an indirect (demographic) method, the contribution of mortality from diseases of the circulatory system by age groups to the differences in life expectancy of men in Kuzbass and subjects of the Russian Federation, and elimination reserves of life expectancy were calculated based on the component method. The age-related mortality rates of the Russian Fertility and Mortality Database were used. To identify the incidence of atherosclerosis of the main arteries, 610 patients aged 47.003±4.875 years were examined. Results. Mortality in Kuzbass men from diseases of the circulatory system is higher in all age groups compared to the Russian Federation, except for 20–29 years. In 2022, the difference in life expectancy with the Russian Federation is 3.30 years, of which 0.79 years is the contribution of diseases of the circulatory system (0.23 years – ischemic heart disease, 0.32 years – cerebrovascular diseases). The elimination reserve associated with the exclusion of mortality from diseases of the circulatory system is 5.78 years. In a random sample, we found a high occurrence of asymptomatic atherosclerosis in men of employable age (61.35%). Arterial hypertension as one of the leading risk factors for the development of atherosclerosis was revealed in almost half of the examined individuals (43.2%). Limitations of the study are related to the duration of the preventive medical examination. Conclusion. Regional features of the life expectancy of Kuzbass men and the impact of mortality from circulatory system diseases, a significant proportion of which is associated with atherosclerosis, have been identified. The elimination of mortality from diseases of the circulatory system promotes an increase in the life expectancy of Kuzbass men by 5.78 years.

Significance: This article is about assessing changes in selected indicators of public health against the background of the pandemic of a new coronavirus infection COVID-19 in adult population of the Siberian Federal District - a territory of the Russian Federation with a special climatic, geographical and ecological "portrait", characterized by a high prevalence of risk factors for chronic non-communicable diseases. The study of this issue creates prerequisites for a detailed analysis of the leading causes of death and peculiar features of their statistical coding in the Siberian Federal District for a given time interval, which helps to identify true mortality from diseases of the circulatory system (in particular, coronary artery disease and myocardial infarction. The purpose of the study was to assess dynamics in the indicators of total mortality and mortality from diseases of the circulatory system in adult population of the Siberian Federal District during the pandemic caused by a new coronavirus infection COVID-19. Material and methods. The study used data of the Federal State Statistics Service «Virtual statistical data mart» official website. The study analyzed non-standardized total mortality rates in adult population of the Siberian Federal District (per 100,000 population), and mortality from diseases of the circulatory system, coronary artery disease and myocardial infarction for the period from 2016 to 2021 and compared these indicators with the all-Russia data. The COVID-19 impact was assessed starting from January 2020, while the period preceding this date was conventionally designated as pre-COVID period. Ranks and econometric analysis of time series were used. Results. In the pre-COVID period, the total mortality rate in adult population was decreasing over time in the Russian Federation and most regions of the Siberian Federal District, with the exception of the Altai Republic. With the onset of the new coronavirus infection, total mortality increased in most regions of the Siberian Federal District, except for the Republic of Tyva. In the Siberian Federal District in the pre-COVID period, mortality from diseases of the circulatory system increased due to a rise in mortality from diseases of the circulatory system in the Altai Republic and Krasnoyarsk region, Irkutsk, Tomsk and Kemerovo regions; mortality from coronary artery disease increased due to a rise in mortality from diseases of the circulatory system in the Krasnoyarsk region, Altai Republic, Kemerovo, Novosibirsk and Tomsk regions; while increased mortality from myocardial infarction is associated with the increased mortality from diseases of the circulatory system in the Republic of Khakassia, Kemerovo, Novosibirsk and Irkutsk regions. With the beginning of the COVID-19 pandemic in 2020, there was an increase in mortality from diseases of the circulatory system and coronary artery disease in the Russian Federation and regions of the Siberian Federal District, including a rise in mortality from myocardial infarction, with the exception of the Altai Republic, and the Irkutsk region. In the Siberian Federal District in 2021, there was no increase in mortality from diseases of the circulatory system and coronary artery disease in the republics of Tyva and Khakassia, the Novosibirsk region and Krasnoyarsk Territory (only from coronary artery disease); mortality from myocardial infarction - in all regions of the Siberian Federal District, except the Tomsk region. Conclusion. The tendency towards lower total mortality in adult population in the pre-COVID period in the Russian Federation and the Siberian Federal District has changes towards increasing starting from official registration of COVID-19 cases. A similar trend is typical of diseases of the circulatory system (including coronary artery disease and myocardial infarction) in the Russian Federation and some regions of the Siberian Federal District. The COVID-19 pandemic is obviously associated with changes in public health indicators in the Russian Federation

This paper reports on the findings from the study of mortality from diseases of the circulatory system (DCS) in Russian nuclear workers of the Mayak Production Association (22 377 individuals, 25.4% female) who were hired at the facility between 1948 and 1982 and followed up until the end of 2018. Using the AMFIT module of the EPICURE software, relative risks (RRs) and excess RRs per unit absorbed dose (ERR/Gy) for the entire Mayak cohort, the subcohort of workers who were residents of the dormitory town of Ozyorsk and the subcohort of migrants from Ozyorsk were calculated based on maximum likelihood. The mean cumulative liver absorbed gamma-ray dose from external exposure was 0.45 (0.65) Gy (mean (standard deviation)) for men and 0.37 (0.56) Gy for women. The mean cumulative liver absorbed alpha dose from internal exposure to incorporated plutonium was 0.18 (0.65) Gy for men and 0.40 (1.92) Gy for women. By the end of the follow-up, 6019 deaths with DCS as the main cause of death were registered among Mayak Production Association workers (including 3828 deaths in the subcohort of residents and 2191 deaths in the subcohort of migrants) over 890 132 (622 199/267 933) person-years of follow-up. The linear model that took into account non-radiation factors (sex, attained age, calendar period, smoking status and alcohol drinking status) and alpha radiation dose (via adjusting) did not demonstrate significant associations of mortality from DCS, ischaemic heart disease (IHD) and cerebrovascular disease with gamma-ray exposure dose in the entire cohort, the resident subcohort or the migrant subcohort (either in men or women). For the subcohort of residents, a significant association with gamma dose was observed for mortality from ischaemic stroke in men with ERR/Gy = 0.43 (95% CI 0.08; 0.99); there were no significant associations with liver absorbed gamma dose for any other considered outcomes. As for internal exposure, for men no significant associations of mortality from any DCS with liver absorbed alpha dose were observed, but for women positive associations were found for mortality from DCS (the entire cohort and the resident subcohort) and IHD (the entire cohort). No significant associations of mortality from various types of DCS with neutron dose were observed either in men or women, although neutron absorbed doses were recorded in only 18% of the workers.

The problem of incidence rate among workers of the main professions of the coal mining industry is traditionally considered from the perspective of occupational pathologies. At the same time, the issues of the spread of production-related somatic diseases among this category of the employable population are undeservedly left without due attention. The objective of the study was assessing the frequency of somatic pathology occurrence in workers of coal pits in the South of Kuzbass. 489 workers of the main professions of coal pits in the South of the Kemerovo region were examined (men aged 22 to 55 years, who were randomized into 2 groups according to the level of exposure to a complex of unfavorable factors of the production environment). The first group with a higher level of exposure to harmful and hazardous production factors of class 3.3 and 3.4 included 196 people: machinists of mining and technological equipment, machinists of drilling rigs, explosives; the second group with the level of danger and harmfulness of class 3.1 and 3.2 consisted of 293 workers, namely, drivers of technological motor vehicles. The study of the frequency of somatic pathology was carried out depending on the length of work experience and the age of the subjects. Each group was divided into subgroups: by the age and work experience. In group 1, somatic pathologies were detected in 52.0% of the cases, in group 2 - in 44.4% (χ2=2.772, p=0.096). In the structure of somatic diseases in the group with a higher class of danger and harmfulness, diseases of the circulatory system (38.24%), diseases of the musculoskeletal system and connective tissue (12.75%) and diseases of the nervous system (8.82%) prevailed; in the group with a lower hazard class there were also diseases of the circulatory system (33.85%), diseases of the musculoskeletal system and connective tissue (14.62%), diseases of the nervous system (12.31%). The frequency of somatic diseases is recorded in a direct linear relationship with the work experience and age of coal pit workers. Limitations. This study is limited to a sample of workers in the main professions of coal pits undergoing periodic medical examinations at the Research Institute for Complex Problems of Hygiene and Occupational Diseases. Conclusion. In the structure of somatic diseases of workers of the main professions of coal pits in the South of Kuzbass, three nosological forms occupy a leading position: diseases of the circulatory system, diseases of the musculoskeletal system and connective tissue, and the nervous system. Among the surveyed workers employed in coal pits with a higher level of exposure to harmful and hazardous production factors, a 100% incidence of somatic diseases was revealed among the respondents aged more than 41 years and with work experience over 21 years. These data should be taken into account when carrying out periodic medical examinations, preventive medical examinations, for the development and implementation of therapeutic and prophylactic measures and post-shift rehabilitation programs. Ethics. The study was conducted in compliance with the standards of the Bioethical Committee of the Research Institute for Complex Problems of Hygiene and Occupational Diseases, established in accordance with the Helsinki Declaration of the World Association "Ethical Principles for Conducting Human Scientific Medical Research" as amended in 2013 and the "Rules of Clinical Practice in the Russian Federation", approved by the Order of the Ministry of Health of the Russian Federation No. 266 of 19.06.2003. All subjects signed an informed consent to participate in the study.

Significance. The study analyzes dynamics in incidence of the most common socially significant pathology - diseases of the circulatory system in the Far Eastern Federal District and the Russian Federation as a whole with due regard to the territorial and economic prospects for the Far East development. The purpose of the study was to analyze incidence of diseases of the circulatory system and their individual types on the example of the Far Eastern Federal District and the Russian Federation as a whole, as well as to compare short-term and long-term projections and actual data. Material and methods. The study has undertaken a comparative analysis of the dynamics in predictive and actual indicators of the overall incidence and incidence of diseases of the circularity system and individual nosological forms over five-year and ten-year periods until 2021. The period of the coronavirus infection (COVID-19) pandemic has been separately analyzed. Results. In general, a more intensive increase in morbidity in the Russian Federation and the Far Eastern Federal District has been identified in comparison with the projected increase. For 5 years prior to 2019, the increase in the overall incidence of diseases of the circulatory system in the Russian Federation turned out to be almost 4 times higher than projected, while incidence was more than 2 times higher than projected. During the COVID-19 pandemic (from 2017 to 2021), the growth dynamics slowed down significantly, 2-fold exceeding the projected overall incidence and more than 1.5-fold the projected incidence. Such trends may be a consequence of the effective ongoing preventive measures aimed at early detection of diseases. Against this background, there is a decrease in the growth rate of the incidence of diseases of the circulatory system in the Russian Federation and the Far Eastern Federal District in the context of the pandemic of a new coronavirus infection. In the Far Eastern Federal District in 2017-2021, compared with the pre-pandemic period, there was a decrease in the overall incidence increase by 65.5% with the increase inversion in incidence. During the period including the pandemic, the Russian Federation and the Far Eastern Federal District registered a negative growth rate of the overall incidence and incidence of ischemic and cerebrovascular diseases. The noted decrease in the actual incidence rates of diseases of the circulatory system, which is not comparable with the projected trends, requires an analysis of causes of the change in the epidemiological situation under the influence of the COVID-19 pandemic. Conclusion and scope of application. In general, we suppose that a decrease in the growth rate in incidence indicators in the Russian Federation and the Far Eastern Federal District during the pandemic of a new coronavirus infection cannot have a long-term impact on epidemiological indicators of diseases of the circulatory system. However, it indicates the necessity to develop reserves of the healthcare system in order to prevent such situations in future.

Introduction One of the most common and serious problems in the practice of Occupational Health Services (OHS) are musculoskeletal diseases. The aim The aim of this study was to clarify the subjective impression of OHS for diseases generating the most frequent and long-term sick leaves from work and representing the most serious health problems for workers. Methods We implemented online based and direct survey of OHS from the official Register of the Ministry of Health (the total number of OHS there was 495), the questionnaire consists of 18 questions. We received 77 completed questionnaires, statistically analysed with SPSS 11.1. A special attention was paid on the questions x 12 A, 12 B and 15. The respondents could give more than one answer. Results It was found that the diseases generating the most frequent sick leave were the diseases from Class X(diseases of the respiratory system), followed by Class IX (diseases of the circulatory system) and Class XIII (diseases of the musculoskeletal system and connective tissue), n = 74 – IX-11 ( 14.86%), X-68 (91.89%), XIII-9 (12.16%). The diseases that generate long-term sick leave were leaded by the diseases Class II, IX, XIX XIII, n = 69, II-40 (57.97%), IX-36 (52.17%), XIII-15 (21.74%), XIX-20 (28.99%). The most serious health problems of workers related to their work (question x15), according to OHS are diseases of the musculoskeletal system and connective tissue – 32 (50.79%), diseases of the circulatory system – 28 (31.75%) and Nervous System – 20 (31.75%), n = 63. Conclusion The results confirm the importance of musculoskeletal disorders in occupational pathology and point to the use of all achievements of science to reduce them in cooperation of the whole healthcare system.

Risk factors for severe outcomes among members of the United States military hospitalized with pneumonia and influenza, 2000–2012

BACKGROUND: The reduction in morbidity and mortality rates from diseases of the circulatory system (DCS) is one of the greatest challenges in primary care, and the implementation of the Family Health Program provides access to the multisectoral and integrated measures required for dealing with these diseases. OBJECTIVE: To analyze DCS mortality and hospitalization rates before and after the implementation of the Family Health Program, in Londrina, Parana. METHODS: This was an ecological study, comparing DCS, cerebrovascular disease (CbVD) and ischemic heart disease (IHD) mortality rates and hospitalization rates by the SUS, in residents of Londrina, in two 4-year periods: 1997 to 2000, and 2002 to 2005. The data were obtained from the Mortality Information System and the Hospital Information System of the SUS. The ratios between the rates were calculated for both periods at 95% confidence interval. RESULTS: The DCS was the first cause of death in the city, in both quadrennia. The CbVD and IHD accounted for more than 63% of DCS deaths. In comparing the two quadrennia, there was a reduction in CbVD mortality rates, which was significant only for subjects over 59 years, in both genders, and the hospitalization rates increased by 10%. For IHD, no significant change occurred in mortality rates, and there was a 40% increase in hospitalization rates. CONCLUSION: The significant reduction only in CbVD mortality in the elderly suggests the need for expanding health assistance coverage to different population groups and the development of preventive and health promotion measures.

Background Air pollution by fine particulate matter with an aerodynamic diameter ≤ 2.5 μm (PM2.5) is the main environmental risk factor associated with diseases of the circulatory system (DCS), ischemic heart disease (IHD), and cerebrovascular diseases (CBVD). Objective To estimate mortality rates from DCS, IHD, and CBVD (2000-2019) among residents of the 164 neighborhoods of Rio de Janeiro, according to PM2.5 levels. Methods This retrospective ecological study used georeferenced satellite data classified into three PM2.5 levels and mortality records from the Department of Information and Informatics of the Unified Health System for DCS, IHD, and CBVD among individuals of both sexes aged ≥ 20 years from 2000 to 2019. Age-adjusted mortality rates per 1,000 inhabitants were calculated, and comparative statistical analyses were performed by sex, PM2.5 level, and age group (5% significance). Results Approximately 91% of the 4.7 million residents (≥ 20 years) live in areas with high or extreme PM2.5 pollution. Deaths occurred up to 3.4 years earlier among men living in highly polluted areas compared with those in moderately polluted areas. The highest DCS mortality rates were observed in neighborhoods with high and extreme pollution (female = 3.9 ± 1.7; 95% CI = 3.5-4.2; male = 4.6 ± 2.1; 95% CI = 4.1-4.9), particularly in individuals aged ≥ 70 years. Significant associations were found between mortality rates and pollution levels for DCS (p = 0.019), IHD (p = 0.025), and CBVD (p = 0.002) in the 50-69-year age group when comparing moderately and extremely polluted areas. Intermediate/high social vulnerability was identified in 71% of neighborhoods, with an increasing socioenvironmental gradient linking higher vulnerability to higher PM2.5 concentrations (R = 0.354; p = 0.001). Conclusion Mean PM2.5 concentrations in the neighborhoods of Rio de Janeiro exceeded the World Health Organization’s recommended standard by a factor of four. Mortality from DCS is significantly higher and occurs earlier in areas with high or extreme levels of pollution.

Significance. According to World Health Organization, in the structure of deaths among youths, external causes and diseases of the circulatory system combined account for 72.0%. The study analyzed prevalence and incidence of diseases of the circulatory system, the 2027 forecast and the structure of incidence of diseases of the circulatory system for the period from 2014 to 2022. Purpose. To identify trends in prevalence and incidence of diseases of the circulatory system in children aged 15-17, and their forecast. Material and methods. The study used materials of the statistical reporting of the Russian Research Institute of Health on prevalence and incidence of diseases of the circulatory system in children aged 15-17 in 2014-2022 within the territory of the Russian Federation, the Volga Federal District, the Udmurt Republic and bordering regions: the Kirov Region and the Republic of Bashkortostan. Results The study found that within the territory of the Udmurt Republic, in 2014-2022, there was a tendency towards decreasing prevalence and incidence of diseases of the circulatory system in children aged 15-17 – by 15.7 and 38.1% (from 7540.2 to 6353.7 and from 1915.3 to 1185.0, respectively). The 2027 forecast is also characterized by a downward trend – a decrease by 11.6 and 6.4% (from 6353.7 to 5620.0 and from 1185.0 to 1044.4, respectively). Conclusion. The diseases identified in the structure of incidence of diseases of the circulatory system (incidence of chronic rheumatic heart diseases, prevalence and incidence of diseases characterized by high blood pressure and prevalence of other heart diseases), in comparison with the Russian Federation, the Volga Federal District, the Republic of Bashkortostan and the Kirov region require the implementation of evidence-based studies at the regional level in order to identify morbidity risk factors and to develop relevant prevention programs. Keywords: morbidity trends in children aged 15-17; diseases of the circulatory system; morbidity dynamics; chronic rheumatic heart disease; high blood pressure; other heart diseases; regional characteristics; forecast; prevention.

Significance. Diseases of the circulatory system are a class of diseases of high social importance and a reservoir for reducing mortality and increasing life expectancy, primarily through improving specialized medical care for working-age patients. The purpose of this study is to assess the results of improving specialized medical care for cardiovascular patients under the federal project “Fight against cardiovascular diseases”. Material and Methods. The analysis is based on data from statistical collections of the Federal Research Institute for Health Organization and Informatics of the Ministry of Health of the Russian Federation, and was focused on evaluating target and actual indicators of the federal project “Fight against cardiovascular diseases”. The content analysis of normative legal documents regulating provision of medical care to patients with cardiovascular diseases has been undertaken. Results. Results of the federal project implemented from October 1st, 2018 to December 31st, 2023, are as follows: 374 regional vascular centers and primary vascular departments were re-equipped (retrofitted); more than 310,000 therapeutic X-ray endovascular interventions were performed; 95.5% of patients who underwent through major cardiovascular surgery are provided with free medications; more than 70% of patients with a high risk of acute cardiovascular event are under medical follow-up and received medical care; hospital mortality from myocardial infarction is under 10%, and hospital mortality from acute cerebrovascular accidents is under16.2%. The standardized mortality rate from diseases of the circulatory system in Russia as a whole decreased by 6.0% in 2022 compared to 2018 and equaled to 408.8 per 100,000population. Conclusion. Implementation of the federal project “Fight against cardiovascular diseases” has made it possible to increase effectiveness of specialized medical care delivery in the Russian Federation primarily due to improved material and technical resources of health care facilities. Coverage of cardiovascular patients with quality clinical follow-up is a hard-to-implement component of the overall process of care delivery to such patients, requiring on-going improvements in the implementation approaches. Progress towards this target is the lowest. In order to achieve quality results in reducing morbidity and mortality from cardiovascular diseases, it is important to timely improve the regulatory framework rather than only develop the resource component.

<jats:p>INTRODUCTION Chronic non-contagious diseases: heart and blood vessel diseases, malignant tumors, diabetes, obstructive pulmonary disease, injuries and poisoning, mental health disorders and others, have dominated the world and our national pathology for decades. Arterial hypertension is one of the most common diseases of the present, which affects in more than 60% of people over the age of 60, and represents a risk factor for infarction, insult, chronic heart failure, renal insufficiency, progressive atherosclerosis and dementia, indicating the importance of hypertension frequency testing in the geriatric population in our country and in the world. OBJECTIVE is to point out the specificity, the high frequency and the risk of hypertension in the geriatric population in our country and in the world. METHODS We analyzed the data and literature in the field of geriatrics, internal medicine, neurology, public health, social medicine and health statistics in the part dealing with the protection of the health of the elderly in our country and in the world. The research was conducted through the analysis of previous scientific research obtained from the literature and the search of electronic databases in accordance with the areas defined in the aim of the work. Using the analytical observational method, all necessary data on this topic were collected, recorded and analyzed. A systematic review of the literature in the researched area was carried out, with the aim of reviewing the methodological characteristics of published studies in the mentioned area. Relevant papers based on this search were collected in full text. Data were extracted from such works, analyzed and presented in this paper. RESULTS AND DISCUSSION Cardiovascular disease is the primary cause of elderly mortality, and it is believed that by removing it in people over the age of 65, the life expectancy would be prolonged for 16 years. The results of some studies show that a third of patients over the age of 65 have isolated systolic hypertension, which is a significant risk factor for apoplexy. In developed countries, the geriatric population is on the rise and reaches more than 30% of the general population, and cardiovascular disease is one of the most common diseases and causes of mortality in this population. Studies have shown that the incidence of myocardial infarction and cerebrovascular events is doubled in patients over 65 years of life with hypertension. Only two groups of diseases, heart and blood vessels diseases and malignant tumors, account for over half of all causes of death. In the Republic of Serbia, in 2021 the population aged 65 and over accounted for 21.28% of the population, while the percentage representation of very old people, over 85 years of age, is constantly increasing. Observed since 2002, more than 100,000 people die annually in Serbia from all causes of death, and almost every second resident of Serbia dies from diseases of the heart and blood vessels. The burden of diseases of the circulatory system or diseases of the heart and blood vessels is on the rise globally, and in recent years in Serbia, on average, 55% of people who have died are victims of one of the diseases from this group. The most common diagnosis within the group of diseases of the cardiovascular system is essential arterial hypertension. The most common causes of death in 2021 belong to the following groups of diseases (according to ICD-10 - International Classification of Diseases of the World Health Organization): Diseases of the circulatory system 41.4%; Tumors 15.1%; Diseases of the respiratory system 5.3%; Diseases of glands with internal secretion, nutrition and metabolism 2.6%. Diseases of the heart, blood vessels and malignant tumors accounted for over half (55.7%) of all causes of death in 2021 in Serbia. As many as 41.4% of all deaths were the result of dying from diseases of the circulatory system, and every sixth person who died (15.1%) was a victim of a malignant tumor. Studies have shown that in patients over 65 years of age with hypertension, the frequency of myocardial infarction and cerebrovascular events is twice as high. CONCLUSION Hypertension is very common in elderly and is a growing problem for them, their family and entire community, as it significantly affects the quality of their lives. The number of elderly in general population is increasing and a growing number of them is with hypertension. Successful prevention can significantly affect the reduction in the incidence of this disease in the population of elderly, which would certainly be one of the priority tasks in improving their health and quality of life.</jats:p>

Background:administrative healthcare data are among main components of hospital information system. Such data can be analyzed and deployed for a variety of purposes. The principal aim of this research was to depict trends of administrative healthcare data from HIS in a general hospital from March 2011 to March 2014.Methods:data set used for this research was extracted from the SQL database of the hospital information system in Razi general hospital located in Marand. The data were saved as CSV (Comma Separated Values) in order to facilitate data cleaning and analysis. The variables of data set included patient’s age, gender, final diagnosis, final diagnosis code based on ICD-10 classification system, date of hospitalization, date of discharge, LOS(Length of Stay), ward, and survival status of the patient. Data were analyzed and visualized after applying appropriate cleansing and preparing techniques.Results:morbidity showed a constant trend over three years. Pregnancy, childbirth and the puerperium were the leading category of final diagnosis (about 32.8 %). The diseases of the circulatory system were the second class accounting for 13 percent of the hospitalization cases. The diseases of the digestive system had the third rank (10%). Patients aged between 14 and 44 constituted a higher proportion of total cases. Diseases of the circulatory system was the most common class of diseases among elderly patients (age≥65). The highest rate of mortality was observed among patients with final diagnosis of the circulatory system diseases followed by those with diseases of the respiratory system, and neoplasms. Mortality rate for the ICU and the CCU patients were 62% and 33% respectively. The longest average of LOS (7.3 days) was observed among patients hospitalized in the ICU while patients in the Obstetrics and Gynecology ward had the shortest average of LOS (2.4 days). Multiple regression analysis revealed that LOS was correlated with variables of surgery, gender, and type of payment, ward, the class of final diagnosis and age.Conclusion:this study presents trends in administrative health care data residing in hospital information system of a general public hospital. Patterns in morbidity, mortality and length of stay can inform decision making in health care management. Mining trends in administrative healthcare data can add value to the health care management.

Purpose of the study: to study changes in the structure of causes of death among those who died aged 18 years and older according to medical death certificates (MDC) and to discuss the problems of assessing the contribution of certain groups of diseases and conditions to the mortality of the population. Materials and methods. The source of information was the electronic database of the Main Directorate of the Civil Registry Office (USR registry office of the Moscow Region) of the MSS for those who died at the age of 18 and older for 2019, 2021 and 2022. one of the subjects of the Russian Federation. Results: All 3 years 99 % of deaths occur in 12 classes of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10); 3 classes (diseases of the circulatory system – DCS, nervous system – DNS and neoplasms) accounted for 70 % of deaths in 2019, 58 % in 2021 and 62 % in 2022 (the share decreased due to COVID-19). The share of DCS was 40 %, 32 % and 37.7 %; neoplasms – 15.3 % 10.9 % and 13.5 %. The greatest decrease in mortality was noted in the class of mental and behavioural disorders (MBD; 8 times: 58.4 in 2019 and 7.4 per 100 thousand in 2022). The proportion of male deaths over all 3 years was higher in the classes of injury and poisoning (IP), infectious diseases (ID), diseases of the respiratory system (DRS) and digestive system diseases (DDS). The highest age of the deceased was registered according to the classes of DNS and diseases of the genitourinary system (DGS); the youngest age in ID and IP classes. For all 3 years, more than 60 % of deaths in a hospital are registered in the classes of ID and DDS, and in 2021 and 2022 from COVID-19. Deaths at home predominate in the class of DNS and ill-defined conditions (class R). For individual codes in the classes of DCS, DNS, MBD, DGS, representing non-prohibited but unspecified causes of death, significant changes (hundreds and thousands of cases) were revealed in dynamics, which is probably due to a change in approaches to coding primary cause of death and affects the structure of mortality by classes and individual reasons. Conclusions. Significant annual changes in the number of deaths from individual causes, differences in demographic characteristics by ICD classes require clarification of the criteria for using individual 4-digit codes and subsequent analysis of mortality for clinically related groups of diseases.

Relevance. Epidemiological studies of diseases of the circulatory system show that this nosological form is one of the leading causes of mortality among all other pathologies detected in most regions of the Russian Federation and around the world. Over the past decade, there has been a significant increase in the incidence of this pathology. The aim of the study is to study the dynamics of mortality in the Krasnoyarsk region from diseases of the circulatory system, as well as problems in the system of prevention, early diagnosis, medical care and rehabilitation of patients. Materials and methods. The analysis was carried out on the basis of information materials of the Unified Interdepartmental Information and Statistical System, the Federal State Statistics Service, documents of regional executive authorities in the field of healthcare. Statistical indicators of morbidity and mortality from cardiovascular diseases from 2011 to 2021 (per 100,000 population) were studied; the results obtained in the Krasnoyarsk region were compared with those in the Russian Federation as a whole. To assess the general and annual trend, its degree of reliability, a trend line was constructed and the value of the approximation coefficient R2 was calculated, which in all cases turned out to be acceptable. The results of the study. Regional mortality rates from diseases of the circulatory system differed from the national average. From 2012 to 2018, there was a slight downward trend, however, in 2019-2022, an increase in this indicator was recorded by more than 9%. In the Krasnoyarsk region, the trend line turned out to be slightly lower than the average for the Russian Federation during the period from 2012 to 2017. However, if in 2012 the difference was more than 15%, by the end of 2017 the gap had narrowed to 2%. Further, it almost coincided with that on average in the Russian Federation, and after 2019 it turned out to be higher. With the introduction and implementation of the regional program "Fight against cardiovascular diseases", a noticeable decrease in mortality was noted. The conclusion was made about the need for further implementation of this program, its continuous improvement and exchange of experience with other regions.