All-cause and cause-specific mortality differences between migrant workers and local workers: a population-based cohort study in Denmark

Nonalcoholic fatty liver disease (NAFLD) has been associated with sarcopenia. However, mortality in the setting of NAFLD-related sarcopenia remains undefined. We aim to determine the all-cause and cause-specific mortality from sarcopenia among adults with NAFLD in the USA. 11065 individuals in the Third National Health and Nutrition Examination Survey were studied and linked mortality through 2015 was analysed. NAFLD was diagnosed based on presence of ultrasonographic hepatic steatosis without other known liver diseases. Sarcopenia was defined as skeletal muscle index determined by bioelectrical impedance analysis. The Cox proportional hazard model was used to assess all-cause mortality and cause-specific mortality, and hazard ratio (HR) adjusted for known risk factors. During a median follow-up of 23years or more, sarcopenia was associated with increased all-cause mortality (HR 1.27, 95% confidence interval [CI] 1.11-1.44). Only in individuals with NAFLD, sarcopenia was associated with a higher risk for all-cause mortality, while this association was absent in those without NAFLD. Individuals with both sarcopenia and NAFLD had a higher risk for all-cause mortality (HR 1.28 95% CI 1.06-1.55) compared with those without sarcopenia and NAFLD. Furthermore, sarcopenia was associated with a higher risk for cancer- and diabetes-related mortality among those with NAFLD. This association was not noted in those without NAFLD. In this nationally representative sample of US adults, sarcopenia was associated with a higher risk for all-cause, cancer- and diabetes-related mortality in individuals with NAFLD.

BackgroundAgeing populations experience greater risks associated with health and survival. It increases the relevance of identifying variables associated with mortality. Grip strength (GS) has been identified as an important biomarker for all cause and cardiovascular mortality, however, its prognostic value has not been studied in Lithuania. The aim of the present study is to evaluate the relationship of GS to vital status in a representative sample of the Lithuanian 45–72-year-old urban population during the period of 12 years of follow-up and to explore associations of GS with all-cause mortality and mortality from cardiovascular diseases (CVD).MethodsWithin the framework of the international study Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE) 7,115 men and women 45–72 years of age were examined in the baseline survey (2006 to 2008). Data from the Official Lithuanian Mortality Register were used to evaluate CVD and all-cause mortality from follow-up till 2020. Cox proportional hazards regression was used, and four models for all-cause and CVD mortality were assessed.ResultsThe mean GS was significantly higher among survivors’ men and women as compared to individuals deceased from CVD and other causes of death. In survivor men and women groups, minimal values of GS in all terciles were higher as compared to all three deceased groups. In both men and women groups, the lowest GS (1st tercile) was associated with a significantly higher risk of all-cause and CVD mortality as compared to the highest levels of GS (3rd tercile) in three Cox regression models. In both men and women were found to have a 1.34- and 1.35-fold higher risk of all-cause mortality, respectively, at lower GS, but no significant difference in the risk of CVD mortality. When GS was treated in all models as decrement per 1 kg and decrement per 1 SD, in both men and women, the risk of all-cause mortality significantly increased with decreasing of GS.ConclusionsThe mean GS was significantly higher among survivors’ men and women as compared to deceased from CVD and other causes of death. Risk of all-cause mortality significantly increased with decreasing of GS.

Serum 25-hydroxyvitamin D, frailty, and mortality among the Chinese oldest old: Results from the CLHLS study

The region called ‘Eastern Europe’ in Korea lies between three European seas - the Adriatic Sea, the Baltic Sea, and the Black Sea. In the Polish academic world, this region was called Central Europe, Central-Eastern Europe, Central and Eastern Europe, Central and Southern Europe, or several other ways, depending on time and conditions. And each of these names had justification to be called that. In this paper, the authors will focus on the use of the term ‘Central Europe’ and make the argument. Based on the research achievements of the Institute of Political Studies, the Polish Academy of Sciences, the current discourse in Polish academic world is the subject of this thesis. Numerous attempts have been made to define the concept of Central Europe in Polish literature on international relations. In this process, controversy often arose over which countries should be included in the Central European region. In this paper, while developing the thesis on Central European terminology, it was divided into four stages by period. With the outbreak of the Russian-Ukrainian War in 2022, the concept of ‘Central-Eastern Europe’, which was widely used in Polish academic world, began to lose its reason for existence. In the authors’ opinion, it seems logical to refer to the territory of the Three Seas Initiative as Central Europe. In other words, we conclude that it is reasonable to call Central Europe the group of 12 countries of the Three Seas Initiative, which are members of the European Union.

In late 2025, the Institute for Health Metrics and Evaluation (IHME) at the University of Washington–Seattle released the estimates from the Global Burden of Disease Study 2023 (GBD 2023). We now report the time trends in myelodysplastic syndromes and myeloproliferative neoplasms (MDS/MPN) burden from 1990 to 2023, across GBD Super Regions, GBD Regions, and countries stratified by the Socio-Demographic index (SDI), according to the 2016 revision to the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia [1]. The GBD framework classifies all countries into seven Super Regions—High-Income; Latin America and Caribbean; Sub-Saharan Africa; North Africa and Middle East; South Asia; Southeast Asia, East Asia, and Oceania; and Central Europe, Eastern Europe, and Central Asia—based on epidemiological similarity, cause-of-death patterns, and geographic proximity. These Super Regions are further subdivided into 21 GBD Regions [2]. The SDI is a composite measure of national development status, calculated as the geometric mean of scaled values for total fertility rate among females under 25, average years of education for individuals aged 15 and older, and lag-distributed income per capita [3]. Countries are grouped into five SDI quintiles: Low, Low-middle, Middle, High-middle, and High. These classifications capture heterogeneity in population structures, governance, and healthcare systems. For reference, other international organizations use different regional classifications—for example, the six WHO regions, the seven World Bank regions, and the World Bank income-based groupings [4, 5]. The burden of MDS/MPN was assessed using age-standardized rates for incidence (ASIR), mortality (ASMR), and disability-adjusted life years (DALYs) (ASDR) in 1990 and 2023, along with their annual percent changes (APCs). DALYs are defined as the sum of years lived with disability (YLDs) and years of life lost (YLLs). Rates were reported per 100 000 person-years and standardized using the GBD global reference population, accounting for changes in population size and age structure. All estimates include 95% uncertainty intervals (UIs), and differences were considered statistically significant when the 95% UIs did not overlap. MDS/MPN-related survival was approximated using the age-standardized mortality-to-incidence ratio (ASMIR), derived from point estimates of ASIR and ASMR for 1990 and 2023. The methodology underlying GBD estimates has been detailed elsewhere [6-9]. Across the seven GBD Super Regions, none of them recorded a decline in ASIR, ASMR, and ASDR (Table 1). In particular, ASIR and ASMR significantly increased everywhere, except for Sub-Saharan Africa, where both were stable over time; similarly, ASDR worsened in five Super Regions, except for Sub-Saharan Africa and South Asia, with unchanged estimates. Central Europe, Eastern Europe, and Central Asia recorded the most severe boost in the three metrics; on the other side, MDS/MPN occurred very rarely among Sub-Saharan Africa countries. ASMIR markedly worsened across all GBD Super Regions, including High-Income countries too: its value widely ranged from 6.3 to 36.8 in 1990, from 9.5 to 60.7 in 2023. The worst performance for ASMIR in 2023 occurred in South Asia: being almost stable the incidence rate, that for mortality doubled along the study period. Among SDI quintiles, none of them showed improvements in ASIR, ASMR, and ASDR. As for incidence, its age-standardized rate over time increased in three quintiles (except the Low and Low-middle SDI), while those for mortality and DALYs among four ones, except only the Low SDI quintile (Table 2). Of note, a linear relationship linked the SDI quintiles to the increase of the three age-standardized rates, as already discovered for the other oncohematological neoplasms. As happened among Super Regions, ASMIR considerably rose, doubling across the first four SDI quintiles, except the High one; it ranged from 10.3 to 23.1 in 1990, from 17.0 to 40.7 in 2023. Disaggregating the 7 Super Regions into the 21 GBD Regions, ASIR significantly rose in fifteen Regions (across all Super Regions, with the most severe trajectory in the High-Income Asia Pacific Region), was stable in other five, and improved only in Western Sub-Saharan Africa (Table 3). ASMR and ASDR trends mirrored each other: both metrics significantly worsened in thirteen Regions (with the best/worst performances in Oceania/Andean Latin America GBD Regions for mortality rate, and High-Income North America/Andean Latin America for DALYs rate, respectively). These thirteen Regions belong to five Super Regions (except South Asia and Sub-Saharan Africa). As for ASMR and ASDR, both were stable in the remaining eight GBD Regions; none experienced more favorable mortality and DALYs rates over time. The author has nothing to report. Roberto Passera acknowledges unpaid participation on the Data Safety Monitoring Board of the clinical trial “Consolidation with ADCT-402 (loncastuximab tesirine) after immunochemotherapy: a phase II study in BTKi-treated/ineligible Relapse/Refractory Mantle Cell Lymphoma (MCL) patient”; unpaid membership in the EBMT Statistical Committee, European Society for Blood and Marrow Transplantation; previous membership of the IRB/IEC Comitato Etico AO SS. Antonio e Biagio Alessandria-ASL AL-VC; all outside the submitted work. All data regarding the GBD Study 2023 are available at https://ghdx.healthdata.org.

Higher levels of thyroid-stimulating hormone (TSH) in the euthyroid state can negatively affect the metabolic health, including nonalcoholic fatty liver disease (NAFLD). We studied the effect of TSH levels in the setting of normal levels of thyroid hormone on all-cause and cause-specific mortality stratified by NAFLD status. The National Health and Nutrition Examination Survey (NHANES) III from 1988 to 1994 and NHANES III-linked mortality data through 2015 were used. NAFLD was defined as ultrasonographically diagnosed hepatic steatosis without coexisting liver diseases. Subclinical hypothyroidism was defined as a TSH level over 4.5 mIU/L and "low-normal" thyroid function as higher TSH level (2.5-4.5 mIU/L) within the euthyroid reference range. The Cox proportional hazard model analyzed the all-cause mortality and cause-specific mortality. In a multivariate logistic regression analysis, individuals with low thyroid function demonstrated an association with NAFLD in a dose-dependent manner. During a median follow-up of 23 years, low thyroid function was associated with increased all-cause mortality only in the univariate model. Low thyroid function was associated with a higher risk for all-cause mortality in individuals with NAFLD and not in those without NAFLD. Furthermore, low thyroid function was associated with a higher risk for cardiovascular mortality in the entire population and among those with NAFLD but demonstrated no association with the non-NAFLD group. In this large nationally representative sample of American adults, low thyroid function was associated with NAFLD and a predictor of higher risk for all-cause and cardiovascular mortality in individuals with NAFLD.

Rural areas have higher cardiovascular disease (CVD) incidence and age-adjusted mortality rates in the general population. However, the impact of rurality on CVD development and outcomes in patients with prostate cancer (PC) remains unclear. This retrospective cohort study used the SEER-Medicare database to analyze males aged ≥65 years diagnosed with PC between 2009 and 2017. The primary exposures were patient rurality status (metropolitan, urban, or rural) and patient-provider rurality, which combined the provider's status (metropolitan vs nonmetropolitan) with the patient's rurality. The primary outcomes included post-PC CVD (comprising heart failure, atrial fibrillation, acute myocardial infarction, peripheral artery disease, and ischemic stroke), cardiovascular mortality (CVDm), prostate cancer-specific mortality (PCSm), and all-cause mortality. Multivariable Fine-Gray and extended Cox models were used to assess the impact of rurality impact on these outcomes. A total of 103,327 older men were included in the study, of whom 3,631 were from rural areas and 1,857 were rural patients with nonmetropolitan providers. Compared with metropolitan patients, those from rural areas had a 28% higher risk of PCSm (subdistribution hazard ratio [SHR], 1.28; 95% CI, 1.14-1.44) and a 15% higher risk of all-cause mortality (adjusted hazard ratio [aHR], 1.15; 95% CI, 1.07-1.23). Compared with urban patients, rural patients had a 7% higher risk of CVD (SHR, 1.07; 95% CI, 1.01-1.13). No significant differences were observed in CVDm. Among patients receiving androgen deprivation therapy (n=16,811), rurality was associated with a 27% higher risk of PCSm (SHR, 1.27; 95% CI, 1.07-1.51) and a 29% higher risk of all-cause mortality (aHR, 1.29; 95% CI, 1.12-1.49). Rural patients who received care from nonmetropolitan providers had higher risks of PCSm and all-cause mortality compared with those treated by metropolitan providers. Rurality is associated with higher risks of CVD, PCSm, and all-cause mortality compared with metropolitan and urban patients. Provider rurality further increases these risks, underscoring the critical role of health care access and quality in rural health disparities.

Introduction & Objective: The presence of NAFLD has been shown to significantly increase the risk of CVD and mortality, but their clarity in individuals with T2DM remains unclear. We aim to explore whether NAFLD and liver fibrosis affect CVD risk, all-cause and cause-specific mortality in individuals with T2DM. Methods: This population-based cohort analyzed data of 14,990 individuals with T2DM from the UK biobank. NAFLD was identified by fatty liver index (FLI), and liver fibrosis was identified by BARD, Fibrosis-4 index (FIB-4) and NAFLD fibrosis score (NFS). Cox models were used to estimate the associations of NAFLD and liver fibrosis with CVD, all-cause and cause-specific mortality. Results: Among 14,990 participants with T2DM (mean [SD] age, 58.7 [7.4] years; 8 237 [54.9%] men), there were 1,429 coronary heart disease, 985 heart failure, 595 stroke and 1,904 deaths. NAFLD was associated with an increased risk of coronary heart disease (HR: 1.65, 95% CI: 1.22-2.23), and a high FLI (quartile 4) was linked to a 110% higher risk of heart failure (95% CI: 1.52-2.90), a 91% higher risk of all-cause mortality (95% CI: 1.54-2.39), and an 83% higher risk of cancer mortality (95% CI: 1.30-2.59). Participants at high risk for fibrosis had a significantly higher risk of all-cause mortality than those at low risk for fibrosis (BARD, HR: 1.65, 95% CI: 1.14-2.38; FIB-4, HR: 1.68, 95% CI: 1.37-2.06; NFS, HR: 1.49, 95% CI: 1.29-1.73). A high risk for fibrosis determined by the NFS and FIB-4 was also linked with higher risks of mortality from CVD (HR: 1.59, 95% CI: 1.17-2.15) and cancer (HR: 1.53, 95% CI: 1.09-2.16), respectively. Conclusion: These findings suggest that NAFLD and liver fibrosis are associated with elevated risks of major CVD, all-cause and cause-specific mortality in individuals with T2DM. Assessing individuals with T2DM for the presence and progression of NAFLD during clinical consultations is recommended. Disclosure S. Xu: None. Q. You: None. L. Liu: None. Funding This work was supported by the Key project of Hubei Natural Science Foundation Innovation and Development Joint Fund (Grant number 2023AFD031), and the Science and Technology Research Key Project of Education Department of Hubei Province China (Grant number D20212602).

The broader mortality risks faced by household members following a suicide remain poorly understood, particularly in low- and middle-income countries. To estimate the risk of all-cause and cause-specific mortality among surviving household members after a suicide within the household and to identify individual and contextual factors associated with mortality risk using data from a national population-based cohort in Brazil. This nationwide cohort study used data from the 100 Million Brazilian Cohort linked to the Mortality Information System (SIM) (2001-2018). All individuals who lived in a household with a suicide index case were considered exposed. Data were analyzed from March 2023 to September 2025. All-cause mortality, cause-specific mortality, and suicide. Outcomes were derived from the national mortality tracking system. The adjusted hazard ratio of all-cause and specific-cause mortality was calculated using a multivariate, time-varying Cox regression. The risk factors associated with increased mortality, including characteristics of the index case, surviving household members, household conditions, and the timing since the suicide event were also analyzed. The cohort included 101 million individuals, of which there were 47 982 suicide index cases identified. Household members exposed to a suicide (11 070 [7%] Black, 82 407 [53%] Parda, and 57 726 [37%] White) had a 32% higher risk of all-cause mortality (adjusted hazard ratio [aHR], 1.32; 95% CI, 1.28-1.36). The risk of suicide among exposed individuals was more than 4 times higher (aHR, 4.42; 95% CI, 3.86-5.07), with 101 of these deaths (44%) occurring within 2 years of the index suicide case. The population attributable fraction for suicide was 77%. Elevated risks were also observed for other external causes (eg, assault and falls) and nonexternal causes (eg, neoplasms and circulatory and respiratory diseases). Mortality risk was highest when the index case was female and younger, among male survivors, and individuals aged 25 to 59 years. Better household conditions were associated with lower risks of both suicide and all-cause mortality. Exposure to suicide within the household was associated with a substantial increase in both suicide-specific and all-cause mortality among surviving household members, particularly in the immediate aftermath. These findings underscore the urgent need to incorporate targeted postvention strategies into comprehensive suicide prevention efforts.

Our aims were to investigate the trends in observed vs expected all-cause mortality and the effects of serostatus and sex on all-cause and cause-specific mortality in individuals with rheumatoid arthritis (RA) in a large community-based longitudinal cohort study. This retrospective cohort study evaluated all-cause and cause-specific mortality in RA using a community population-based inception cohort of adult residents of Olmsted County, Minnesota, with incident RA from 1980 to 2019 meeting American College of Rheumatology 1987 criteria, and non-RA residents matched 3:1 to patients with RA by age and sex. Underlying cause of death was obtained from death certificates. Competing risks/cumulative incidence methods were used to compare cause-specific mortality incidence between individuals with and without RA. Cox models estimated the effect of RA on risk of cause-specific mortality, adjusting for sex, age, and calendar year of index. Interactions for RA with sex, age, seropositivity, and calendar year were examined. The study included 1337 patients with RA and 4011 non-RA comparators. All-cause mortality was significantly increased in both female and male individuals with RA, specifically in seropositive RA, and declined after the 1980s. The increased risk of death due to respiratory causes in patients with RA was significantly different depending on seropositive vs seronegative status (adjusted hazard ratio 2.26 [95% CI 1.56-3.26] vs 0.52 [95% CI 0.24-1.13], interaction P < 0.001). There were no significant differences in cause-specific mortality based on sex. Seropositivity in persons with RA associates with a significantly increased risk of death, particularly due to respiratory causes, whereas no increased risk was found in seronegative patients.

Neutrophil percentage-to-albumin ratio (NPAR) is a novel inflammatory biomarker and correlated with the progression and clinical outcomes of many diseases. This investigation aimed to clarified the association between NPAR and mortality risk among hypertension patients. The database of the National Health and Nutrition Examination Survey provided the patient data for hypertension. Using a restricted cubic spline (RCS), the association between the NPAR and mortality risk was investigated. In order to assess the independent risk contribution of the NPAR in all-cause and cerebrovascular mortality, weighted Cox proportional hazards models were employed. Concordance index and receiver operating characteristic (ROC) curve were employed to assess how effectively the NPAR predicted the mortality risk at different times. A total of 6,866 hypertension cases was included in this investigation. During follow-up, 2,757 (40%) patients have died, 582 (8.5%) of them from cerebrovascular disease. RCS regression analysis found a positive nonlinear correlation between NPAR and all-cause and cerebrovascular mortality of hypertension patients. High NPAR indicated higher risks of all-cause mortality (HR = 1.81, 95% CI 1.52–2.37) and cerebrovascular mortality (HR = 2.21, 95% CI 1.67–2.88) among hypertension patients, and these results remained after adjusting certain clinical parameters. The areas under the curve of for 5-year, 10-year and 15-year ROC for all-cause mortality were 0.720, 0.703 and 0.634, and those for cerebrovascular mortality were 0.705, 0.706 and 0.699, respectively. NPAR served as s a biomarker for all-cause and cerebrovascular mortality in hypertension patients. Higher NPAR indicated higher risk of all-cause and cerebrovascular mortality.

BackgroundThe circadian clock and endoplasmic reticulum stress signaling play important roles in oncogenesis and development of cancer. Sleep disorders have been linked to an elevated risk of mortality in general populations. Nonetheless, the evidence for the sleep disorders-mortality association among cancer patients is limited. We aimed to prospectively investigate the association of sleep disorders with all-cause, cancer, and cardiovascular disease (CVD) mortality among cancer individuals.MethodsWe assessed 3187 participants with cancer from the National Health and Nutrition Examination Survey 2005–2016 cohorts with a median follow-up time of 83.0 months. Multivariable Cox proportional hazards models estimated the adjusted hazard ratio (HR) and 95% confidence interval (CI).ResultsMultivariable Cox proportional hazards models showed that sleep disorders were associated with a higher risk of all-cause mortality (HR 1.23, 95%CI: 1.06,1.42), cancer mortality (HR 1.30, 95%CI: 1.02, 1.66), and cardiovascular disease mortality (HR 1.35, 95%CI: 1.02, 1.80). After the total group was stratified by gender, the high HRs were observed in men (P < 0.05), not in women. The correlation between sleep disorders and higher long-term mortality was also significant after individuals who died within 2 years of follow-up were excluded, with HR 1.24 (95%CI: 1.07, 1.45) in model I, HR 1.20 (95%CI: 1.02, 1.42) in model II for long-term all-cause mortality, HR (95%CI: 1.00, 1.74) in model I for long-term cancer mortality, and HR 1.5 (95%CI:1.12, 2.02) in model I, HR 1.45 (95%CI: 1.06, 1.99) in model II for long-term CVD mortality.ConclusionsSleep disorders were associated with a higher risk of all-cause mortality, cancer mortality, and CVD mortality, as well as long-term mortality in cancer patients. Our finding underlies the importance of screening for sleep disorders for all cancer survivors and the urge to integrate sleep health as an important part of cancer care more effectively. Male individuals may be particularly vulnerable and could benefit from more frequent screening.

The prevalence of chronic obstructive pulmonary disease (COPD) is rising in China, yet population-based evidence on COPD-related mortality risk remains limited. This study examined the association between prevalent COPD and all-cause and cause-specific mortality in a large Chinese cohort. 484,301 adults aged 30 to 79 years who received spirometry at the baseline of the China Kadoorie Biobank Study (2004-2008) were included. COPD was defined as FEV1/ FVC < 0.7. Mortality data were tracked via local death registries and national health insurance systems over a median follow-up period of 16.0 years. Cox proportional hazard models and competing risk regression were used to estimate hazard ratios (HRs) and subdistribution HRs (SHRs), respectively. The COPD group had higher all-cause and cause-specific mortality, with adjusted HR (95%CI) for all-cause mortality of 1.44 (1.41-1.47), and adjusted SHR (95%CI) of 1.09 (1.05-1.13), 1.06 (1.01-1.11), 3.30 (3.12-3.49), 1.45 (1.16-1.81), for circulatory disease, neoplasms, respiratory disease, and infectious disease mortality, respectively. Specifically, young COPD (aged < 50 years) showed a stronger mortality association than those aged ≥ 50 years. Moreover, individuals with preserved ratio impaired spirometry (PRISm) had a 1.4-fold higher risk of all-cause mortality compared with non-COPD participants. COPD is associated with a significantly elevated risk of mortality from all causes, circulatory disease, neoplasms, respiratory disease, and infectious disease in the Chinese population. Additionally, young COPD and those with PRISm faced significant mortality burdens.

BackgroundThere is a bidirectional effect between sleep disorders and Mediterranean diet (MED), but the joint effect of MED and sleep disorders on mortality is unclear. The aim of this study was to investigate whether there is a synergistic effect of adherence to MED and sleep disorders on all-cause and cause-specific mortality.MethodsThe study included 23,212 individuals in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2014. A 9-point evaluation score, alternative Mediterranean diet (aMED) index was used to assess adherence to MED. Sleep disorder and hours of sleep were assessed by structured questionnaires. Cox regression models were used to assess the relationship between sleep disorders, aMED and all-cause mortality, cause-specific mortality (cardiovascular-related death, cancer-related death). The interaction effect of sleep disorders with aMED on mortality was further assessed.ResultsResults showed that participants with lower aMED and presence of sleep disorders had significantly higher risk of all-cause mortality and cardiovascular-related mortality (HR, 2.16, 95% CI, 1.49–3.13, P < 0.0001; HR, 2.68, 95% CI, 1.58–4.54, P = 0.0003). A significant interaction effect was found between aMED and sleep disorders on cardiovascular mortality (p for interaction = 0.033). No significant interaction existed between aMED and sleep disorders on all-cause mortality (p for interaction = 0.184) and cancer-related mortality (p for interaction = 0.955).ConclusionsPoorer adherence to MED and sleep disorders synergistically increased long-term all-cause mortality and cardiovascular mortality in NHANES population.

To examine the factors that determine upon alcohol consumption pattern with drinking consequences among male adult Myanmar migrant workers in Ratchaburi Province, Thailand, the cross-sectional study conducted during March, 2012. The multistage sampling method was applied in 347 respondents for quantitative research. The data was collected in face to face structured interview questionnaire. The tools for accessing the research objectives were adapted from image using pattern assessments, AUDIT and MAST for consequences. The data were clarified by applying descriptive statistics for interpretation of data and inferential statistic to examine the association between independent variables and alcohol consumption by using Chi-Square test. The result revealed that current drinking behavior prevailed at 73.8% among male migrant workers and 41.4% of them were young age between 18 and 25 years. The excessive amount of alcohol consumption than standard drink per occasion was behaved by 58.2% of current drinkers. The types of alcohol beverage that migrant workers preferred most were beer, white spirit and whiskey respectively. Approximate 63.3% of migrant drinkers consumed alcohol more than once a week while 8% of respondents drank white spirit daily. The migrants classified as alcohol-related problematic consequences according to MAST scores were 21.48% of current drinkers. Heavy drinking behavior with consequences were associated with increasing in age, especially in married and divorced marital status, more durable in length of migration and fluent language proficiency. The determine factors for alcohol drinking among migrant workers were mainly for socialization, job condition as regarding the alcohol for amusement and being relaxant for tired condition. The other frequent reasons were to relieve stress, like taste and peer pressure. Most of migrants still lacked of knowledge about the alcoholic health effect on low birth weight in women and HIV. Knowledge and perception upon alcohol were not quite different among current drinkers and non-drinkers. Common quitting characters were health reason and avoidance during Buddhist Lent period. Overall finding reported that hazardous drinking behaviors among cavalier migrant workers realm; should be considered and work-related alcohol reduction intervention should consider for behavior change and other policy like kin-based educational messages delivery system and quit promotion during Buddhist Lent period campaign should establish in the whole country both Thai workers and migrants workers alike especially with language translation if possible. This will be in accordance with universally recommended alcohol reduction strategies but to the extent that there is a missing in the vulnerable migrant groups.