Artificial Intelligence Applied to Software Testing: A Literature Review

Artificial intelligence has been applied in wildfire science and management since the 1990s, with early applications including neural networks and expert systems. Since then, the field has rapidly progressed congruently with the wide adoption of machine learning (ML) methods in the environmental sciences. Here, we present a scoping review of ML applications in wildfire science and management. Our overall objective is to improve awareness of ML methods among wildfire researchers and managers, as well as illustrate the diverse and challenging range of problems in wildfire science available to ML data scientists. To that end, we first present an overview of popular ML approaches used in wildfire science to date and then review the use of ML in wildfire science as broadly categorized into six problem domains, including (i) fuels characterization, fire detection, and mapping; (ii) fire weather and climate change; (iii) fire occurrence, susceptibility, and risk; (iv) fire behavior prediction; (v) fire effects; and (vi) fire management. Furthermore, we discuss the advantages and limitations of various ML approaches relating to data size, computational requirements, generalizability, and interpretability, as well as identify opportunities for future advances in the science and management of wildfires within a data science context. In total, to the end of 2019, we identified 300 relevant publications in which the most frequently used ML methods across problem domains included random forests, MaxEnt, artificial neural networks, decision trees, support vector machines, and genetic algorithms. As such, there exists opportunities to apply more current ML methods — including deep learning and agent-based learning — in the wildfire sciences, especially in instances involving very large multivariate datasets. We must recognize, however, that despite the ability of ML models to learn on their own, expertise in wildfire science is necessary to ensure realistic modelling of fire processes across multiple scales, while the complexity of some ML methods such as deep learning requires a dedicated and sophisticated knowledge of their application. Finally, we stress that the wildfire research and management communities play an active role in providing relevant, high-quality, and freely available wildfire data for use by practitioners of ML methods.

LoRaWAN technology’s reliability is challenged by weather parameters, which can influence the communication channel design, especially when dealing with outdoor devices. We propose to analyze this effect by evaluating the relationship between the received signal strength indicator (RSSI) and different weather parameters, as well as its temporal changes. A rigorous statistical analysis of the RSSI sequences is conducted to assess if they could be represented by a specific statistical model. For this purpose, several models are investigated. The Artificial Intelligence (AI) algorithms cover machine learning (ML) and deep learning methods are appealing when dealing with time series forecasting. Nevertheless, the classical autoregressive integrated moving average (ARIMA) model can be an attractive alternative due to its simplicity. Therefore, this work proposes a comparative study of ARIMA, AI, and hybrid approaches to forecast the RSSI using weather parameters as regressors. The considered AI algorithms are the artificial neural network (ANN), support vector machine (SVM), random forest (RF), and Long Short-Term Memory (LSTM). Also, hybrid models are constructed, coupling the ARIMA with them. The models are evaluated in time series of RSSI, measured by eight different LoRaWAN transmitter nodes and considering the temperature, pressure, relative humidity, and rain as weather parameters. Our analysis reveals that temperature is the dominant factor among weather parameters, and negatively affects RSSI. The ARIMA model that uses only the temperature as a regressor provides consistently better fits than the ARIMA without regressors. Moreover, coupling the ARIMA with the temperature as a regressor and the ANN (ARIMA-ANN) is the best option among the pure AI and hybrid approaches. However, it provided accuracy measures very close to those obtained from the ARIMA model fitted in the first stage, with similar performance. Therefore, the ARIMA model considering the temperature is the most competitive alternative when analyzing RSSI measurements, with the advantage of being the most straightforward method. These results suggest that the RSSI from the analyzed LoRaWAN receiver nodes may not present nonlinear patterns and, considering several weather parameters, they are affected mainly by the outdoor temperature.

This review delves into the fascinating realm of microbial insights enabled by artificial intelligence (AI), unveiling the mysteries of the intricate gut environment. Research into the human microbiome has evolved due to the fast development of AI and Machine learning (ML). Never before have such novel avenues for individualized medical care and therapeutic therapies been available as a result of this. Our first stop is at software developed specifically for microbiome data analysis. Complex datasets can be accessed and valuable information extracted using AI algorithms and machine learning approaches. Next, we take a look at predictive modeling of gut microbial interactions. Here we see how AI can foretell the actions of microorganisms and their effects on host health and illness. Afterwards, we investigate the efficacy of AI in detecting microbe biomarkers, which are crucial indicators of gut health and potential dangers of disease. A disease's root cause can be identified and a treatment strategy developed using this innovative approach. We also delve into the realm of personalized microbiome analysis and demonstrate how AI may assist in making dietary and lifestyle adjustments that are most suited to each individual in order to enhance their health. The impact of AI extends beyond the realm of research and assessment and include the development of novel medications. Our focus is on the ways AI is assisting the hunt for novel probiotics and microbiome-based therapies, which could one day lead to the development of effective remedies for various medical conditions. However, although we anticipate AI's potential, we must equally consider the ethical considerations involved in studying microbiota. This paper highlights the significance of data protection, transparency, and bias reduction in ensuring the responsible and fair use of AI. We can maximize AI's potential without trampling on people's rights or exacerbating existing inequalities if we adhere to ethical guidelines and work to earn the public's trust. Finally, this study demonstrates the potential power of AI-driven microbiome discoveries. By being committed to ethical principles and vigilant in our pursuit of new challenges, we may advance microbiota research toward a future of data-driven, customized healthcare that utilizes AI as a valuable tool for optimal health and wellness.

A dose deposition matrix (DDM) prediction method using several voxel features and a machine learning (ML) approach is proposed for plan optimization in radiation therapy. Head and lung cases with the inhomogeneous medium are used as training and testing data. The prediction model is a cascade forward backprop neural network where the input is the features of the voxel, including 1) voxel to body surface distance along the beamlet axis, 2) voxel to beamlet axis distance, 3) voxel density, 4) heterogeneity corrected voxel to body surface distance, 5) heterogeneity corrected voxel to beamlet axis, and (6) the dose of voxel obtained from the pencil beam (PB) algorithm. The output is the predicted voxel dose corresponding to a beamlet. The predicted DDM was used for plan optimization (ML method) and compared with the dose of MC-based plan optimization (MC method) and the dose of pencil beam-based plan optimization (PB method). The mean absolute error (MAE) value was calculated for full volume relative to the dose of the MC method to evaluate the overall dose performance of the final plan. For patient with head tumor, the ML method achieves MAE value 0.49 × 10-4 and PB has MAE 1.86 × 10-4. For patient with lung tumor, the ML method has MAE 1.42 × 10-4 and PB has MAE 3.72 × 10-4. The maximum percentage difference in PTV dose coverage (D98) between ML and MC methods is no more than 1.2% for patient with head tumor, while the difference is larger than 10% using the PB method. For patient with lung tumor, the maximum percentage difference in PTV dose coverage (D98) between ML and MC methods is no more than 2.1%, while the difference is larger than 16% using the PB method. In this work, a reliable DDM prediction method is established for plan optimization by applying several voxel features and the ML approach. The results show that the ML method based on voxel features can obtain plans comparable to the MC method and is better than the PB method in achieving accurate dose to the patient, which is helpful for rapid plan optimization and accurate dose calculation. Establishment of a new machine learning method based on the relationship between the voxel and beamlet features for dose deposition matrix prediction in radiation therapy.

Chemical heuristics have been fundamental to the advancement of chemistry and materials science. These heuristics are typically established by scientists using knowledge and creativity to extract patterns from limited datasets. Machine learning offers opportunities to perfect this approach using computers and larger datasets. Here, we discuss the relationships between traditional heuristics and machine learning approaches. We show how traditional rules can be challenged by large-scale statistical assessment and how traditional concepts commonly used as features are feeding the machine learning techniques. We stress the waste involved in relearning chemical rules and the challenges in terms of data size requirements for purely data-driven approaches. Our view is that heuristic and machine learning approaches are at their best when they work together.

Simple SummaryThe primary purpose of this review is to provide an in-depth analysis of existing Artificial Intelligence (AI) algorithms used in the field of prostate cancer (PC) for diagnosis and treatment. This review aims to show the research community that AI-enabled technologies have the potential for widespread growth and penetration of PC diagnostics and therapeutics to simplify and accelerate existing healthcare processes.As medical science and technology progress towards the era of “big data”, a multi-dimensional dataset pertaining to medical diagnosis and treatment is becoming accessible for mathematical modelling. However, these datasets are frequently inconsistent, noisy, and often characterized by a significant degree of redundancy. Thus, extensive data processing is widely advised to clean the dataset before feeding it into the mathematical model. In this context, Artificial intelligence (AI) techniques, including machine learning (ML) and deep learning (DL) algorithms based on artificial neural networks (ANNs) and their types, are being used to produce a precise and cross-sectional illustration of clinical data. For prostate cancer patients, datasets derived from the prostate-specific antigen (PSA), MRI-guided biopsies, genetic biomarkers, and the Gleason grading are primarily used for diagnosis, risk stratification, and patient monitoring. However, recording diagnoses and further stratifying risks based on such diagnostic data frequently involves much subjectivity. Thus, implementing an AI algorithm on a PC’s diagnostic data can reduce the subjectivity of the process and assist in decision making. In addition, AI is used to cut down the processing time and help with early detection, which provides a superior outcome in critical cases of prostate cancer. Furthermore, this also facilitates offering the service at a lower cost by reducing the amount of human labor. Herein, the prime objective of this review is to provide a deep analysis encompassing the existing AI algorithms that are being deployed in the field of prostate cancer (PC) for diagnosis and treatment. Based on the available literature, AI-powered technology has the potential for extensive growth and penetration in PC diagnosis and treatment to ease and expedite the existing medical process.

Background & Problem Statement - Software testing is a critical phase in the software development lifecycle (SDLC), ensuring that applications function correctly, meet user requirements, and maintain high- quality standards. Traditional software testing approaches, including manual testing and rule-based automation, often face challenges in scalability, efficiency, and adaptability to dynamic software environments. Traditional testing methods are overwhelmed by complex software systems which slows down defect detection and extends both testing costs and release schedules. Machine Learning (ML) has emerged as a transformative solution, introducing predictive and adaptive capabilities that optimize test case selection, automate defect detection, and enhance overall software quality assurance (QA). This study explores the integration of ML in software testing, addressing the challenges of traditional QA methodologies and demonstrating how AI-driven frameworks improve testing efficiency. Methodology - To investigate the impact of ML in software testing, this research adopts a systematic approach by analyzing ML-driven test automation techniques, including predictive testing, adaptive test execution, and automated test case generation. Research reviews how Google Microsoft Facebook IBM and Deep Code put ML-based quality assurance frameworks into operation. The study leverages supervised learning, reinforcement learning, deep learning, and NLP-based techniques to demonstrate how ML models predict software defects, dynamically adapt test cases, and optimize testing resources. The research tests how ML-based testing models operate within CI/CD pipelines to improve ongoing testing and deployment flow. Analysis & Results - The analysis of ML-driven software testing reveals that predictive analytics improves early defect detection rates. It helps developers spend 37% less time debugging their work. Adaptive testing models, including self-healing test scripts, minimize maintenance costs by 50% and enhance test reliability in agile environments. The integration of NLP-based test case generation increases test coverage. NLP technology enables automatic connection between requirements and test cases at 89% success rate. Additionally, reinforcement learning techniques improve test case selection, reducing redundant test executions by 43%. Our research shows different ML methods work well to lessen incorrect error alerts. ML integration for QA surely increasing defect prediction accuracy and optimizing test execution time. Findings & Contributions - This research contributes to the field of AI-driven software testing by providing a comprehensive framework for ML-based QA methodologies. Our study shows that machine learning helps find more software problems better adapts test cases and lowers testing expenses to solve present software development needs. The study also identifies critical challenges, including data availability, model interpretability, and computational overhead, suggesting future research directions in Explainable AI (XAI), hybrid AI-ML testing models, and AI-driven security testing. As the industry moves toward AI-first software testing, this research paves the way for fully autonomous QA frameworks, enabling intelligent, scalable, and cost- effective software validation techniques. Keywords - Machine Learning, Software Testing, Quality Assurance, Predictive Testing, Adaptive Testing, Test Automation, Defect Prediction, Self- Healing Test Scripts, AI-Driven QA, Reinforcement

Background The use of artificial intelligence (AI) algorithms for the diagnosis of skin diseases has shown promise in experimental settings but has not yet been tested in real-life conditions. The COVID-19 pandemic led to a worldwide disruption of health systems, increasing the use of telemedicine. There is an opportunity to include AI algorithms in the teledermatology workflow. Objective The aim of this study is to test the performance of and physicians’ preferences regarding an AI algorithm during the evaluation of patients via teledermatology. Methods We performed a prospective study in 340 cases from 281 patients using patient-taken photos during teledermatology encounters. The photos were evaluated by an AI algorithm and the diagnosis was compared with the clinician’s diagnosis. Physicians also reported whether the AI algorithm was useful or not. Results The balanced (in-distribution) top-1 accuracy of the algorithm (47.6%) was comparable to the dermatologists (49.7%) and residents (47.7%) but superior to the general practitioners (39.7%; P=.049). Exposure to the AI algorithm results was considered useful in 11.8% of visits (n=40) and the teledermatologist correctly modified the real-time diagnosis in 0.6% (n=2) of cases. Algorithm performance was associated with patient skin type and image quality. Conclusions AI algorithms appear to be a promising tool in the triage and evaluation of lesions in patient-taken photographs via telemedicine. Conflicts of Interest None declared.

Assessments of genomic prediction accuracies using artificial intelligent (AI) algorithms (i.e., machine and deep learning methods) are currently not available or very limited in aquaculture species. The principal aim of this study was to examine the predictive performance of these new methods for disease resistance to Edwardsiella ictaluri in a population of striped catfish Pangasianodon hypophthalmus and to make comparisons with four common methods, i.e., pedigree-based best linear unbiased prediction (PBLUP), genomic-based best linear unbiased prediction (GBLUP), single-step GBLUP (ssGBLUP) and a nonlinear Bayesian approach (notably BayesR). Our analyses using machine learning (i.e., ML-KAML) and deep learning (i.e., DL-MLP and DL-CNN) together with the four common methods (PBLUP, GBLUP, ssGBLUP, and BayesR) were conducted for two main disease resistance traits (i.e., survival status coded as 0 and 1 and survival time, i.e., days that the animals were still alive after the challenge test) in a pedigree consisting of 560 individual animals (490 offspring and 70 parents) genotyped for 14,154 single nucleotide polymorphism (SNPs). The results using 6,470 SNPs after quality control showed that machine learning methods outperformed PBLUP, GBLUP, and ssGBLUP, with the increases in the prediction accuracies for both traits by 9.1–15.4%. However, the prediction accuracies obtained from machine learning methods were comparable to those estimated using BayesR. Imputation of missing genotypes using AlphaFamImpute increased the prediction accuracies by 5.3–19.2% in all the methods and data used. On the other hand, there were insignificant decreases (0.3–5.6%) in the prediction accuracies for both survival status and survival time when multivariate models were used in comparison to univariate analyses. Interestingly, the genomic prediction accuracies based on only highly significant SNPs (P < 0.00001, 318–400 SNPs for survival status and 1,362–1,589 SNPs for survival time) were somewhat lower (0.3–15.6%) than those obtained from the whole set of 6,470 SNPs. In most of our analyses, the accuracies of genomic prediction were somewhat higher for survival time than survival status (0/1 data). It is concluded that although there are prospects for the application of genomic selection to increase disease resistance to E. ictaluri in striped catfish breeding programs, further evaluation of these methods should be made in independent families/populations when more data are accumulated in future generations to avoid possible biases in the genetic parameters estimates and prediction accuracies for the disease-resistant traits studied in this population of striped catfish P. hypophthalmus.

Optimized machine learning approaches for identifying vertical temperature gradient on ballastless track in natural environments

IntroductionHIV self-testing (HIVST) is highly sensitive and specific, addresses known barriers to HIV testing (such as stigma), and is recommended by the World Health Organization as a testing option for the delivery of HIV pre-exposure prophylaxis (PrEP). Nevertheless, HIVST remains underutilized as a diagnostic tool in community-based, differentiated HIV service delivery models, possibly due to concerns about result misinterpretation, which could lead to inadvertent onward transmission of HIV, delays in antiretroviral therapy (ART) initiation, and incorrect initiation on PrEP. Ensuring that HIVST results are accurately interpreted for correct clinical decisions will be critical to maximizing HIVST's potential. Early evidence from a few small pilot studies suggests that artificial intelligence (AI) computer vision and machine learning could potentially assist with this task. As part of a broader study that task-shifted HIV testing to a new setting and cadre of healthcare provider (pharmaceutical technologists at private pharmacies) in Kenya, we sought to understand how well AI technology performed at interpreting HIVST results.MethodsAt 20 private pharmacies in Kisumu, Kenya, we offered free blood-based HIVST to clients ≥18 years purchasing products indicative of sexual activity (e.g., condoms). Trained pharmacy providers assisted clients with HIVST (as needed), photographed the completed HIVST, and uploaded the photo to a web-based platform. In real time, each self-test was interpreted independently by the (1) client and (2) pharmacy provider, with the HIVST images subsequently interpreted by (3) an AI algorithm (trained on lab-captured images of HIVST results) and (4) an expert panel of three HIVST readers. Using the expert panel's determination as the ground truth, we calculated the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for HIVST result interpretation for the AI algorithm as well as for pharmacy clients and providers, for comparison.ResultsFrom March to June 2022, we screened 1,691 pharmacy clients and enrolled 1,500 in the study. All clients completed HIVST. Among 854 clients whose HIVST images were of sufficient quality to be interpretable by the AI algorithm, 63% (540/854) were female, median age was 26 years (interquartile range: 22–31), and 39% (335/855) reported casual sexual partners. The expert panel identified 94.9% (808/854) of HIVST images as HIV-negative, 5.1% (44/854) as HIV-positive, and 0.2% (2/854) as indeterminant. The AI algorithm demonstrated perfect sensitivity (100%), perfect NPV (100%), and 98.8% specificity, and 81.5% PPV (81.5%) due to seven false-positive results. By comparison, pharmacy clients and providers demonstrated lower sensitivity (93.2% and 97.7% respectively) and NPV (99.6% and 99.9% respectively) but perfect specificity (100%) and perfect PPV (100%).ConclusionsAI computer vision technology shows promise as a tool for providing additional quality assurance of HIV testing, particularly for catching Type II error (false-negative test interpretations) committed by human end-users. We discuss possible use cases for this technology to support differentiated HIV service delivery and identify areas for future research that is needed to assess the potential impacts—both positive and negative—of deploying this technology in real-world HIV service delivery settings.

The increasing complexity of urban transportation systems and the growing volume of vehicles have made traffic congestion a persistent challenge in modern cities. Efficient traffic flow prediction is essential for mitigating congestion, improving road safety, optimizing traffic signal control, and enhancing overall transportation efficiency. In recent years, artificial intelligence (AI) has emerged as a transformative tool in the field of traffic management, offering sophisticated algorithms capable of modeling, analyzing, and predicting complex traffic patterns with high accuracy. The application of AI in traffic flow prediction leverages vast amounts of real-time and historical data to generate precise forecasts, supporting data-driven decision-making by urban planners and traffic control authorities. The prediction of traffic flow involves analyzing time-series data that exhibit nonlinear, dynamic, and often stochastic behavior. Traditional statistical models, such as autoregressive integrated moving average (ARIMA), have proven to be limited in handling the high dimensionality and variability inherent in traffic systems. In contrast, AI algorithms possess the capacity to learn and adapt from complex data inputs without the need for explicit programming, making them particularly suitable for traffic-related applications. AI algorithms used in traffic flow prediction can be broadly categorized into machine learning (ML) and deep learning (DL) approaches. Machine learning algorithms such as k-nearest neighbors (KNN), support vector machines (SVM), decision trees, and random forests have demonstrated effectiveness in short-term traffic prediction tasks. These algorithms are capable of identifying hidden patterns in traffic data and adjusting to changes in traffic behavior over time. Ensemble methods, which combine the strengths of multiple learning models, further enhance prediction accuracy and robustness. Deep learning algorithms, a subfield of AI inspired by the human brain’s neural architecture, have shown exceptional performance in capturing spatial-temporal dependencies in traffic data. Recurrent neural networks (RNNs), particularly long short-term memory (LSTM) networks and gated recurrent units (GRUs), are widely used for their ability to process sequential data and retain information over extended time intervals. Convolutional neural networks (CNNs) are employed to extract spatial features from traffic sensor data or road network imagery. Hybrid models that integrate CNNs with RNNs have achieved high levels of predictive precision by simultaneously learning spatial and temporal correlations. In addition to supervised learning methods, unsupervised and reinforcement learning techniques are also applied in traffic flow prediction. Clustering algorithms, such as k-means and DBSCAN, assist in identifying traffic patterns, while reinforcement learning models optimize adaptive traffic signal control systems by learning optimal actions through environmental interaction. This study explores the different types of AI algorithms used in traffic flow prediction, examining their theoretical foundations, structural differences, and practical applications. It aims to evaluate the comparative advantages of various algorithms in addressing the challenges of real-time traffic prediction in increasingly complex transportation networks.

Continual learning in medical devices: FDA's action plan and beyond

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Commentary: Machine learning and cardiac surgery risk prediction