BRAIN TUMOR DETECTION USING MACHINE LEARNING AND DEEP LEARNING

Brain tumors (BTs) are spreading very rapidly across the world. Every year, thousands of people die due to deadly brain tumors. Therefore, accurate detection and classification are essential in the treatment of brain tumors. Numerous research techniques have been introduced for BT detection as well as classification based on traditional machine learning (ML) and deep learning (DL). The traditional ML classifiers require hand-crafted features, which is very time-consuming. On the contrary, DL is very robust in feature extraction and has recently been widely used for classification and detection purposes. Therefore, in this work, we propose a hybrid deep learning model called DeepTumorNet for three types of brain tumors (BTs)—glioma, meningioma, and pituitary tumor classification—by adopting a basic convolutional neural network (CNN) architecture. The GoogLeNet architecture of the CNN model was used as a base. While developing the hybrid DeepTumorNet approach, the last 5 layers of GoogLeNet were removed, and 15 new layers were added instead of these 5 layers. Furthermore, we also utilized a leaky ReLU activation function in the feature map to increase the expressiveness of the model. The proposed model was tested on a publicly available research dataset for evaluation purposes, and it obtained 99.67% accuracy, 99.6% precision, 100% recall, and a 99.66% F1-score. The proposed methodology obtained the highest accuracy compared with the state-of-the-art classification results obtained with Alex net, Resnet50, darknet53, Shufflenet, GoogLeNet, SqueezeNet, ResNet101, Exception Net, and MobileNetv2. The proposed model showed its superiority over the existing models for BT classification from the MRI images.

Nowadays, huge amounts of information are available on social networks, blogs, websites, and digital libraries. Most of this information is in unstructured text format, so text mining approaches have become increasingly studied to process all this data. Text classification aims to automatically classify documents into predetermined categories, applying machine learning (ML) algorithms. In this paper, we collected a dataset set related to reviews of a food store in Peru and compared different vectorization models, such as Term Frequency Inverse Document Frequency (TF-IDF), Bag of Words (BoW), and classification algorithms, such as traditional ML classifiers SVM, Decision Tree, MLP, KNN, Naive Bayes and a recent approach “deep jointly informed neural networks” (DJINN) that initialize deep feedforward neural networks based on decision trees. The results show DJINN gets a F1-score higher than traditional ML, being a promising technique for text classification.

Artificial intelligence (AI)-based approaches are crucial in computer-aided diagnosis (CAD) for various medical applications. Their ability to quickly and accurately learn from complex data is remarkable. Deep learning (DL) models have shown promising results in accurately classifying Alzheimer's disease (AD) and its related cognitive states, Early Mild Cognitive Impairment (EMCI) and Late Mild Cognitive Impairment (LMCI), along with the healthy conditions known as Cognitively Normal (CN). This offers valuable insights into disease progression and diagnosis. However, certain traditional machine learning (ML) classifiers perform equally well or even better than DL models, requiring less training data. This is particularly valuable in CAD in situations with limited labeled datasets. In this paper, we propose an ensemble classifier based on ML models for magnetic resonance imaging (MRI) data, which achieved an impressive accuracy of 96.52%. This represents a 3-5% improvement over the best individual classifier. We evaluated popular ML classifiers for AD classification under both data-scarce and data-rich conditions using the Alzheimer's Disease Neuroimaging Initiative and Open Access Series of Imaging Studies datasets. By comparing the results to state-of-the-art CNN-centric DL algorithms, we gain insights into the strengths and weaknesses of each approach. This work will help users to select the most suitable algorithm for AD classification based on data availability.

Deep learning’s swift development has generated substantial excitement about its application in medical imaging. Machine learning (ML) methods can support radiologists in diagnosing breast cancer (BC) without resorting to invasive procedures. However, traditional ML classifiers require the extraction of detailed hand-crafted features, which is a time-intensive task to achieve accurate results. Hence, this paper proposes a novel Feature-driven Breast Cancer Classification using the Modified Loss and Activation function-assisted LeNet (MLAL) model, named F-BCC-ML. The process of detecting BC using mammogram images comprises several key stages. In the first step, the image undergoes enhancement using the Improved Bilateral Filtering Technique (IBFT), which reduces the noise while conserving critical structural details like edges. Next, the image is subjected to segmentation using SegNet, a deep-learning model designed for semantic segmentation. After segmentation, the next phase is feature extraction, where various features like Weber Local descriptor assisted Local Gabor XOR Pattern (WLD-LGXP) for texture analysis, Median Binary Pattern (MBP), colour features, and deep features are derived from the segmented image. Once the features are extracted, they are fed into the classification stage, where the Modified Loss and Activation function assisted LeNet (MLAL) model, more sophisticated Deep Convolutional Neural Network (DCNN) are used to classify the image as either normal or cancerous. The result is a prediction that indicates whether the breast tissue is benign or shows signs of cancer, helping radiologists make more accurate and informed decisions. The MLAL+DCNN accomplished the maximum accuracy of 0.936, precision of 0.947 and F-measure of 0.942, respectively.

Chemical heuristics have been fundamental to the advancement of chemistry and materials science. These heuristics are typically established by scientists using knowledge and creativity to extract patterns from limited datasets. Machine learning offers opportunities to perfect this approach using computers and larger datasets. Here, we discuss the relationships between traditional heuristics and machine learning approaches. We show how traditional rules can be challenged by large-scale statistical assessment and how traditional concepts commonly used as features are feeding the machine learning techniques. We stress the waste involved in relearning chemical rules and the challenges in terms of data size requirements for purely data-driven approaches. Our view is that heuristic and machine learning approaches are at their best when they work together.

Graph theory provides a robust framework for modelling complex relationships in medical data, enhancing classification accuracy through relational learning. Unlike traditional machine learning (ML) models that treat data points independently, graph-based approaches support structural dependencies to improve feature representation. This study explores the application of Graph Attention Networks (GAT), GraphSAGE, Graph Convolutional Network(GCN) and Graph Isomorphism Network (GIN) for breast cancer classification, employing k-nearest neighbor (KNN) graphs to construct a structured dataset where nodes represent patients and edges capture feature similarities. The effectiveness of the graph-based approaches is evaluated against traditional ML classifiers, including Decision Trees, Random Forest, LightGBM, and XGBoost. Experimental results indicate that GCN, GIN, GAT and GraphSAGE are beat conventional methods, with GCN, GAT and GraphSAGE achieved 100% test-accuracy and with GIN achieved 99.42%, to confirm the percentage of accuracy, authors conducted extensive experiments, including robustness testing by reducing KNN connections, introducing noise, and shuffling train-test splits. Results demonstrate that graph-based models are significantly best than traditional ML models, and these graph-based models maintain same classification accuracy while maintaining stability under robustness tests. The findings confirm that graph-based learning provides a scalable, interpretable, and highly accurate alternative for medical classification tasks, proving its effectiveness in distinguishing between benign and malignant tumors.

Medical imaging aids in the analysis of interior parts of the human body such as the functioning of the organs or tissues for early treatment of diseases. Many different types of medical imaging technologies exist, for example, X-ray radiography, magnetic resonance imaging, endoscopy, positron emission tomography, CT scan (computed tomography), and many more. A tumor is an abnormal tissue in the brain which causes damage to the functioning of the cell. Therefore, brain tumor detection is an incredibly tricky task. Manual detection of a tumor is quite risky as it involves the insertion of a needle in the brain. Thus, there is a need for automated brain tumor detection systems. The well-timed detection of the tumor can add to accurate treatment and can increase the survival rate of patients. From machine learning techniques, namely K-nearest neighbor, support vector machine, and more to soft computing techniques, namely artificial neural network, self-organizing map, and others hold a significant stand in detection and categorization of brain tumor. Various methods including deep learning-based classifiers such as convolutional neural network, recurrent neural network, deep belief network (DBN), and others are used to make it easier to detect the tumor. Hybrid classifiers were also used for classification systems such as combining the machine learning approach with soft computing. This study is to summarize and compare the work of various authors on automatic brain tumor detection using medical imaging. Based on the accuracy, specificity, and sensitivity parameters, the results of different techniques are analyzed and compared graphically.

Early diagnosis and treatment is very essential in monitoring Brain tumor using MRI images. Convolutional Neural Networks (CNN) and Machine Learning (ML) classifiers have been widely used but there is not much work on how feature selection techniques would affect the performance of the CNN. Secondly, there is a need for investigation concerning small dataset adaptability and ML-CNN comparisons. To improve the classification accuracy, we integrate Univariate, Recursive Feature Elimination (RFE), Recursive Feature Elimination with Cross Validation (RFECV) with CNN in this study. Preprocessing, feature extraction & selection was carried out on the dataset consisting of 253 MRI images and they are classified using CNN and ML models (Logistic Regression, Decision Tree, Random Forest, Naïve Bayes). With the results 96%, CNN with Univariate Feature Selection performed better than ML classifiers, and other selection techniques. The results demonstrate that feature selection is necessary to get the best performance out of CNN models operating on small datasets. Future studies should be based on different deep learning architectures to improve classification and application in other datasets.

Drug–target interaction (DTI) prediction is a crucial step in drug discovery and repositioning as it reduces experimental validation costs if done right. Thus, developing in-silico methods to predict potential DTI has become a competitive research niche, with one of its main focuses being improving the prediction accuracy. Using machine learning (ML) models for this task, specifically network-based approaches, is effective and has shown great advantages over the other computational methods. However, ML model development involves upstream hand-crafted feature extraction and other processes that impact prediction accuracy. Thus, network-based representation learning techniques that provide automated feature extraction combined with traditional ML classifiers dealing with downstream link prediction tasks may be better-suited paradigms. Here, we present such a method, DTi2Vec, which identifies DTIs using network representation learning and ensemble learning techniques. DTi2Vec constructs the heterogeneous network, and then it automatically generates features for each drug and target using the nodes embedding technique. DTi2Vec demonstrated its ability in drug–target link prediction compared to several state-of-the-art network-based methods, using four benchmark datasets and large-scale data compiled from DrugBank. DTi2Vec showed a statistically significant increase in the prediction performances in terms of AUPR. We verified the "novel" predicted DTIs using several databases and scientific literature. DTi2Vec is a simple yet effective method that provides high DTI prediction performance while being scalable and efficient in computation, translating into a powerful drug repositioning tool.

The detection and classification of depression and other mental disorders have become crucial in the modern era, particularly with the growing reliance on social media for self-expression. Existing systems often face challenges like limited prediction accuracy, difficulty forecasting future mental illnesses, and handling both clinical and non-clinical data. This study proposes a novel analytical model that not only screens individuals' current mental health status from social media content but also predicts the likelihood of future mental health issues. The proposed methodology integrates classical machine learning (ML) models, ensemble learning approaches, and pretrained models for enhanced detection and forecasting accuracy. The outcome shows that pre-trained language models accomplished maximized F1-score and overall performance significantly better than conventional ML and ensemble models. The system outperforms existing methods with a significant accuracy improvement, achieving 90.9% overall accuracy, a 7.2% improvement over traditional ML classifiers, 5.8% over ensemble models, and 11.3% over language models.

The global food security and agricultural sustainability face a major threat from plant diseases. Effective management requires both early and accurate identification of these diseases. The development of Artificial Intelligence (AI) has led Machine Learning (ML) techniques to become promising tools for automated disease detection and classification. The paper presents an extensive evaluation of current progress in employing ML methods for plant disease detection. The role of image processing combined with deep learning and traditional ML classifiers in disease identification is discussed in detail. A detailed literature survey is provided followed by a method- dataset-performance metrics comparison. The paper also discusses future research directions and challenges.

Accurate detection and classification of brain tumors are essential for timely diagnosis and effective treatment planning. This study presents an integrated framework leveraging both machine learning (ML) and deep learning (DL) models for brain tumor detection and classification using MRI images. Two publicly available datasets are utilized: one for binary classification (tumor vs. no tumor) and another for multiclass classification (glioma, meningioma, and pituitary tumors). Comprehensive preprocessing steps, including resizing, feature extraction using the Gray Level Co-occurrence Matrix (GLCM), and feature selection via Chi-square testing, were employed to optimize the dataset for modeling. Machine learning models such as Decision Trees, K-Nearest Neighbors (KNN), Support Vector Machines (SVM), and AdaBoost were compared with deep learning architectures like Convolutional Neural Networks (CNNs) and the pre-trained VGG16 model. Hyperparameter optimization techniques, including grid search and the Adam optimizer, were used to enhance model performance. The models were evaluated using metrics such as accuracy, precision, recall, F1-score, Mean Squared Error (MSE), and Mean Absolute Error (MAE). Results indicate that the VGG16 model consistently outperformed other approaches, achieving high validation accuracy. This study highlights the potential of integrating ML and DL techniques for accurate and efficient brain tumor detection and classification, offering valuable tools for medical diagnostics.

Globally, in 2016, 1 out of 11 adults suffered from diabetes mellitus. Diabetic foot ulcers (DFU) are a major complication of this disease, which if not managed properly can lead to amputation. Current clinical approaches to DFU treatment rely on patient and clinician vigilance, which has significant limitations, such as the high cost involved in the diagnosis, treatment, and lengthy care of the DFU. We collected an extensive dataset of foot images, which contain DFU from different patients. In this DFU classification problem, we assessed the two classes as normal skin (healthy skin) and abnormal skin (DFU). In this paper, we have proposed the use of machine learning algorithms to extract the features for DFU and healthy skin patches to understand the differences in the computer vision perspective. This experiment is performed to evaluate the skin conditions of both classes that are at high risk of misclassification by computer vision algorithms. Furthermore, we used convolutional neural networks for the first time in this binary classification. We have proposed a novel convolutional neural network architecture, DFUNet, with better feature extraction to identify the feature differences between healthy skin and the DFU. Using 10-fold cross validation, DFUNet achieved an AUC score of 0.961. This outperformed both the traditional machine learning and deep learning classifiers we have tested. Here, we present the development of a novel and highly sensitive DFUNet for objectively detecting the presence of DFUs. This novel approach has the potential to deliver a paradigm shift in diabetic foot care among diabetic patients, which represent a cost-effective, remote, and convenient healthcare solution.

Unmanned aerial vehicles (UAVs) are increasingly being integrated into the domain of precision agriculture, revolutionizing the agricultural landscape. Specifically, UAVs are being used in conjunction with machine learning techniques to solve a variety of complex agricultural problems. This paper provides a careful survey of more than 70 studies that have applied machine learning techniques utilizing UAV imagery to solve agricultural problems. The survey examines the models employed, their applications, and their performance, spanning a wide range of agricultural tasks, including crop classification, crop and weed detection, cropland mapping, and field segmentation. Comparisons are made among supervised, semi-supervised, and unsupervised machine learning approaches, including traditional machine learning classifiers, convolutional neural networks (CNNs), single-stage detectors, two-stage detectors, and transformers. Lastly, future advancements and prospects for UAV utilization in precision agriculture are highlighted and discussed. The general findings of the paper demonstrate that, for simple classification problems, traditional machine learning techniques, CNNs, and transformers can be used, with CNNs being the optimal choice. For segmentation tasks, UNETs are by far the preferred approach. For detection tasks, two-stage detectors delivered the best performance. On the other hand, for dataset augmentation and enhancement, generative adversarial networks (GANs) were the most popular choice.

Understanding the structure-activity relationship (SAR) of antibiotic scaffolds is crucial for the development of antibiotics to counter the growing crisis of antimicrobial resistant bacteria. However, an overwhelming space of structural features impairs a comprehensive understanding of the mechanism of action for potential antibiotic candidates. In this study, antibacterial data of a set of newly synthesized cyanine molecules are analyzed with both traditional machine learning (ML) and commercially available large language models (LLMs) to elucidate the SAR. Some LLMs, particularly Grok-3 Think and ChatGPT o1, outperform the traditional ML classifiers, and both approaches highlight positive charges and lipophilicity as key properties for effective cyanine antibiotics.