Feature-driven breast cancer classification via hybrid model using mammogram images

Brain tumor remain one of the most life-threatening forms of cancer, and early and accurate diagnosis is crucialfor effective treatment planning and improving patient outcomes. Magnetic Resonance Imaging (MRI) serves as a primary modality for brain tumor detection; however, manual interpretation of these scans is often time-consuming and subject to inter-observer variability. Recent advances in Machine Learning (ML) and Deep Learning (DL) offer promising tools to automate and enhance tumor detection and segmentation in medical images. This research paper presents a comprehensive study on the application of ML and DL techniques for brain tumor detection, focusing on both classification and segmentation tasks. Various algorithms, including traditional ML classifiers and state-of- the-art Convolutional Neural Networks (CNNs), were evaluated on publicly available datasets. The proposed deep learning models demonstrated superior performance in identifying tumor regions with high accuracy and robustness. Furthermore, the paper discusses the challenges associated with data preprocessing, model interpretability, and real- time deployment, particularly in the context of medical science. The results underscore the potential of integrating ML/DL-based systems into clinical workflows to support radiologists and enhance diagnostic efficiency.

Brain tumors (BTs) are spreading very rapidly across the world. Every year, thousands of people die due to deadly brain tumors. Therefore, accurate detection and classification are essential in the treatment of brain tumors. Numerous research techniques have been introduced for BT detection as well as classification based on traditional machine learning (ML) and deep learning (DL). The traditional ML classifiers require hand-crafted features, which is very time-consuming. On the contrary, DL is very robust in feature extraction and has recently been widely used for classification and detection purposes. Therefore, in this work, we propose a hybrid deep learning model called DeepTumorNet for three types of brain tumors (BTs)—glioma, meningioma, and pituitary tumor classification—by adopting a basic convolutional neural network (CNN) architecture. The GoogLeNet architecture of the CNN model was used as a base. While developing the hybrid DeepTumorNet approach, the last 5 layers of GoogLeNet were removed, and 15 new layers were added instead of these 5 layers. Furthermore, we also utilized a leaky ReLU activation function in the feature map to increase the expressiveness of the model. The proposed model was tested on a publicly available research dataset for evaluation purposes, and it obtained 99.67% accuracy, 99.6% precision, 100% recall, and a 99.66% F1-score. The proposed methodology obtained the highest accuracy compared with the state-of-the-art classification results obtained with Alex net, Resnet50, darknet53, Shufflenet, GoogLeNet, SqueezeNet, ResNet101, Exception Net, and MobileNetv2. The proposed model showed its superiority over the existing models for BT classification from the MRI images.

Graph theory provides a robust framework for modelling complex relationships in medical data, enhancing classification accuracy through relational learning. Unlike traditional machine learning (ML) models that treat data points independently, graph-based approaches support structural dependencies to improve feature representation. This study explores the application of Graph Attention Networks (GAT), GraphSAGE, Graph Convolutional Network(GCN) and Graph Isomorphism Network (GIN) for breast cancer classification, employing k-nearest neighbor (KNN) graphs to construct a structured dataset where nodes represent patients and edges capture feature similarities. The effectiveness of the graph-based approaches is evaluated against traditional ML classifiers, including Decision Trees, Random Forest, LightGBM, and XGBoost. Experimental results indicate that GCN, GIN, GAT and GraphSAGE are beat conventional methods, with GCN, GAT and GraphSAGE achieved 100% test-accuracy and with GIN achieved 99.42%, to confirm the percentage of accuracy, authors conducted extensive experiments, including robustness testing by reducing KNN connections, introducing noise, and shuffling train-test splits. Results demonstrate that graph-based models are significantly best than traditional ML models, and these graph-based models maintain same classification accuracy while maintaining stability under robustness tests. The findings confirm that graph-based learning provides a scalable, interpretable, and highly accurate alternative for medical classification tasks, proving its effectiveness in distinguishing between benign and malignant tumors.

Nowadays, huge amounts of information are available on social networks, blogs, websites, and digital libraries. Most of this information is in unstructured text format, so text mining approaches have become increasingly studied to process all this data. Text classification aims to automatically classify documents into predetermined categories, applying machine learning (ML) algorithms. In this paper, we collected a dataset set related to reviews of a food store in Peru and compared different vectorization models, such as Term Frequency Inverse Document Frequency (TF-IDF), Bag of Words (BoW), and classification algorithms, such as traditional ML classifiers SVM, Decision Tree, MLP, KNN, Naive Bayes and a recent approach “deep jointly informed neural networks” (DJINN) that initialize deep feedforward neural networks based on decision trees. The results show DJINN gets a F1-score higher than traditional ML, being a promising technique for text classification.

Drug–target interaction (DTI) prediction is a crucial step in drug discovery and repositioning as it reduces experimental validation costs if done right. Thus, developing in-silico methods to predict potential DTI has become a competitive research niche, with one of its main focuses being improving the prediction accuracy. Using machine learning (ML) models for this task, specifically network-based approaches, is effective and has shown great advantages over the other computational methods. However, ML model development involves upstream hand-crafted feature extraction and other processes that impact prediction accuracy. Thus, network-based representation learning techniques that provide automated feature extraction combined with traditional ML classifiers dealing with downstream link prediction tasks may be better-suited paradigms. Here, we present such a method, DTi2Vec, which identifies DTIs using network representation learning and ensemble learning techniques. DTi2Vec constructs the heterogeneous network, and then it automatically generates features for each drug and target using the nodes embedding technique. DTi2Vec demonstrated its ability in drug–target link prediction compared to several state-of-the-art network-based methods, using four benchmark datasets and large-scale data compiled from DrugBank. DTi2Vec showed a statistically significant increase in the prediction performances in terms of AUPR. We verified the "novel" predicted DTIs using several databases and scientific literature. DTi2Vec is a simple yet effective method that provides high DTI prediction performance while being scalable and efficient in computation, translating into a powerful drug repositioning tool.

Artificial intelligence (AI)-based approaches are crucial in computer-aided diagnosis (CAD) for various medical applications. Their ability to quickly and accurately learn from complex data is remarkable. Deep learning (DL) models have shown promising results in accurately classifying Alzheimer's disease (AD) and its related cognitive states, Early Mild Cognitive Impairment (EMCI) and Late Mild Cognitive Impairment (LMCI), along with the healthy conditions known as Cognitively Normal (CN). This offers valuable insights into disease progression and diagnosis. However, certain traditional machine learning (ML) classifiers perform equally well or even better than DL models, requiring less training data. This is particularly valuable in CAD in situations with limited labeled datasets. In this paper, we propose an ensemble classifier based on ML models for magnetic resonance imaging (MRI) data, which achieved an impressive accuracy of 96.52%. This represents a 3-5% improvement over the best individual classifier. We evaluated popular ML classifiers for AD classification under both data-scarce and data-rich conditions using the Alzheimer's Disease Neuroimaging Initiative and Open Access Series of Imaging Studies datasets. By comparing the results to state-of-the-art CNN-centric DL algorithms, we gain insights into the strengths and weaknesses of each approach. This work will help users to select the most suitable algorithm for AD classification based on data availability.

The evolution and improvements of deep learning are being used to tackle any research obstacles that could be converted into classification problems in all spheres of life. Each Deep convolutional neural network (DCNN) design's output is determined by the depth and value of the hyperparameters, which explains why so many of them have been proposed. These DCNN architectures must be created entirely from scratch, and they can only be used for the applications for which they were intended. Transfer learning may be used to modify these pre-trained networks so they are more appropriate for particular purposes. This article aims to evaluate the empirical performance of the applicability of pre-trained DCNN models to identify human face presentation threats (FPAD). Human FPAD is one of the most significant and crucial areas of research right now because of the introduction of ambient computing, which necessitates contact-free identification of persons with the help of their biometric traits. Six pre-trained DCNN models are taken into account for an experimental evaluation in human FPAD alias VGG19, VGG16, DensNet121, MobileNet, Xception, and InceptionV3. The investigation makes use of the NUAA and Replay-Attack benchmark FPAD datasets. Thepade's sorted block truncation coding (SBTC) 10-ary features are merged with deep learning features produced from the finest performing finetuned DCNNs to enhance the FPAD capabilities of analyzed machine learning (ML) classifiers. The integration of features of Thepade's SBTC 10-ary and DCNN has considerably increased the FPAD accuracy of ML classifiers with slightly more computations of feature extraction.

Globally, in 2016, 1 out of 11 adults suffered from diabetes mellitus. Diabetic foot ulcers (DFU) are a major complication of this disease, which if not managed properly can lead to amputation. Current clinical approaches to DFU treatment rely on patient and clinician vigilance, which has significant limitations, such as the high cost involved in the diagnosis, treatment, and lengthy care of the DFU. We collected an extensive dataset of foot images, which contain DFU from different patients. In this DFU classification problem, we assessed the two classes as normal skin (healthy skin) and abnormal skin (DFU). In this paper, we have proposed the use of machine learning algorithms to extract the features for DFU and healthy skin patches to understand the differences in the computer vision perspective. This experiment is performed to evaluate the skin conditions of both classes that are at high risk of misclassification by computer vision algorithms. Furthermore, we used convolutional neural networks for the first time in this binary classification. We have proposed a novel convolutional neural network architecture, DFUNet, with better feature extraction to identify the feature differences between healthy skin and the DFU. Using 10-fold cross validation, DFUNet achieved an AUC score of 0.961. This outperformed both the traditional machine learning and deep learning classifiers we have tested. Here, we present the development of a novel and highly sensitive DFUNet for objectively detecting the presence of DFUs. This novel approach has the potential to deliver a paradigm shift in diabetic foot care among diabetic patients, which represent a cost-effective, remote, and convenient healthcare solution.

The detection and classification of depression and other mental disorders have become crucial in the modern era, particularly with the growing reliance on social media for self-expression. Existing systems often face challenges like limited prediction accuracy, difficulty forecasting future mental illnesses, and handling both clinical and non-clinical data. This study proposes a novel analytical model that not only screens individuals' current mental health status from social media content but also predicts the likelihood of future mental health issues. The proposed methodology integrates classical machine learning (ML) models, ensemble learning approaches, and pretrained models for enhanced detection and forecasting accuracy. The outcome shows that pre-trained language models accomplished maximized F1-score and overall performance significantly better than conventional ML and ensemble models. The system outperforms existing methods with a significant accuracy improvement, achieving 90.9% overall accuracy, a 7.2% improvement over traditional ML classifiers, 5.8% over ensemble models, and 11.3% over language models.

The global food security and agricultural sustainability face a major threat from plant diseases. Effective management requires both early and accurate identification of these diseases. The development of Artificial Intelligence (AI) has led Machine Learning (ML) techniques to become promising tools for automated disease detection and classification. The paper presents an extensive evaluation of current progress in employing ML methods for plant disease detection. The role of image processing combined with deep learning and traditional ML classifiers in disease identification is discussed in detail. A detailed literature survey is provided followed by a method- dataset-performance metrics comparison. The paper also discusses future research directions and challenges.

Understanding the structure-activity relationship (SAR) of antibiotic scaffolds is crucial for the development of antibiotics to counter the growing crisis of antimicrobial resistant bacteria. However, an overwhelming space of structural features impairs a comprehensive understanding of the mechanism of action for potential antibiotic candidates. In this study, antibacterial data of a set of newly synthesized cyanine molecules are analyzed with both traditional machine learning (ML) and commercially available large language models (LLMs) to elucidate the SAR. Some LLMs, particularly Grok-3 Think and ChatGPT o1, outperform the traditional ML classifiers, and both approaches highlight positive charges and lipophilicity as key properties for effective cyanine antibiotics.

In today’s digital world, Android phones play a vital part in a variety of facets of both professionals and individuals’ personal and professional lives. Android phones are great for getting things done faster and more organized. The proportionate increase in the number of malicious applications has also been seen to be expanding. Since the play store offers millions of apps, detection of malware apps is challenging task. In this paper, a methodology is introduced for detecting malware in Android applications through the utilization of global image shape transform (GIST) features extracted from grayscale images of the applications. The dataset comprises samples of both malware and benign apps collected from the virus share website. After converting the apps into grayscale images, GIST features are extracted to capture their global spatial layout. Various machine learning (ML) algorithms, such as logistic regression (LR), k-nearest neighbour (KNN), AdaBoost, decision tree (DT), Naïve Bayes (NB), random forest (RF), support vector machine (SVM), extra tree classifier (ETC), and gradient boosting (GB), are employed to classify the applications according to their GIST features. Furthermore, a feed forward neural network (FFNN) is utilized as a deep learning (DL) technique to further improve the accuracy of classification. The performance of each algorithm is evaluated using metrics such as accuracy, precision and recall. The results demonstrated that the FFNN achieves superior accuracy compared to traditional ML classifiers, indicating its effectiveness in detecting malware in Android apps.

Detection of unexpected findings in radiology reports: A comparative study of machine learning approaches

Mobile fitness applications provide the opportunity to show users real-time feedback on their current fitness activity. For such applications, it is essential to accurately track the user's current fitness activity using available mobile sensors, such as inertial measurement units (IMUs). Convolutional neural networks (CNNs) have been shown to produce strong results in different time series classification tasks, including the recognition of daily living activities. However, fitness activities can present unique challenges to the human activity recognition task (HAR), including greater similarity between individual activities and fewer available data for model training. In this paper, we evaluate the applicability of CNNs to the fitness activity recognition task (FAR) using IMU data and determine the impact of input data size and sensor count on performance. For this purpose, we adapted three existing CNN architectures to the FAR task and designed a fourth CNN variant, which we call the scaling fully convolutional network (Scaling-FCN). We designed a preprocessing pipeline and recorded a running exercise data set with 20 participants, in which we evaluated the respective recognition performances of the four networks, comparing them with three traditional machine learning (ML) methods commonly used in HAR. Although CNN architectures achieve at least 94% test accuracy in all scenarios, two traditional ML architectures surpass them in the default scenario, with support vector machines (SVMs) achieving 99.00 ± 0.34% test accuracy. The removal of all sensors except one foot sensor reduced the performance of traditional ML architectures but improved the performance of CNN architectures on our data set, with our Scaling-FCN reaching the highest accuracy of 99.86 ± 0.11% on the test set. Our results suggest that CNNs are generally well suited for fitness activity recognition, and noticeable performance improvements can be achieved if sensors are dropped selectively, although traditional ML architectures can still compete with or even surpass CNNs when favorable input data are utilized.

Early diagnosis and treatment is very essential in monitoring Brain tumor using MRI images. Convolutional Neural Networks (CNN) and Machine Learning (ML) classifiers have been widely used but there is not much work on how feature selection techniques would affect the performance of the CNN. Secondly, there is a need for investigation concerning small dataset adaptability and ML-CNN comparisons. To improve the classification accuracy, we integrate Univariate, Recursive Feature Elimination (RFE), Recursive Feature Elimination with Cross Validation (RFECV) with CNN in this study. Preprocessing, feature extraction & selection was carried out on the dataset consisting of 253 MRI images and they are classified using CNN and ML models (Logistic Regression, Decision Tree, Random Forest, Naïve Bayes). With the results 96%, CNN with Univariate Feature Selection performed better than ML classifiers, and other selection techniques. The results demonstrate that feature selection is necessary to get the best performance out of CNN models operating on small datasets. Future studies should be based on different deep learning architectures to improve classification and application in other datasets.