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  • Curriculum-based TRADES for Robust Skin Lesion Classification under Adversarial Attacks
  • https://doi.org/10.1109/icoici65217.2025.11254705Copy DOI Icon

Curriculum-based TRADES for Robust Skin Lesion Classification under Adversarial Attacks

  • Sep 17, 2025
  • M R Neethunath +2 more
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Abstract

The safe deployment of medical image classifiers is critically dependent on their robustness to adversarial attacks; however, standard defenses often degrade the diagnostic accuracy of clean data. This study introduces Curriculum-based TRADES (C-TRADES), a lightweight and effective training framework that resolves this trade-off. C-TRADES synergistically combines the TRADES loss objective with a curriculum learning strategy, where adversarial perturbations gradually intensify during the training. This approach stabilizes the optimization and yields highly robust models with minimal impact on the clean-data performance. We evaluated C-TRADES on a dermatoscopic skin lesion classification task using DenseNet121 and modern ConvNeXt-Tiny architectures. The results demonstrated a significant improvement in adversarial robustness. Notably, C-TRADES-trained ConvNeXt achieved an exceptional accuracy of 76.4% under AutoAttack, decisively outperforming the standard adversarial training. Crucially, this was achieved while maintaining a high clean data accuracy of 81.8%, showing a superior balance between robustness and diagnostic utility. These findings signify that C-TRADES is a practical and generalizable defense system, establishing a new benchmark for developing trustworthy clinical AI systems that are resilient to adversarial threats.

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