Explainable Ensemble Learning Models for the Rheological Properties of Self-Compacting Concrete

The optimal design of prestressed concrete cylindrical walls is greatly beneficial for economic and environmental impact. However, the lack of the available big enough datasets for the training of robust machine learning models is one of the factors that prevents wide adoption of machine learning techniques in structural design. The current study demonstrates the application of the well-established harmony search methodology to create a large database of optimal design configurations. The unit costs of concrete and steel used in the construction, the specific weight of the stored fluid, and the height of the cylindrical wall are the input variables whereas the optimum thicknesses of the wall with and without post-tensioning are the output variables. Based on this database, some of the most efficient ensemble learning techniques like the Extreme Gradient Boosting (XGBoost), Light Gradient Boosting Machine (LightGBM), Categorical Gradient Boosting (CatBoost) and Random Forest algorithms have been trained. An R2 score greater than 0.98 could be achieved by all of the ensemble learning models. Furthermore, the impacts of different input features on the predictions of different machine learning models have been analyzed using the SHapley Additive exPlanations (SHAP) methodology. The height of the cylindrical wall was found to have the greatest impact on the optimal wall thickness, followed by the specific weight of the stored fluid. Also, with the help of individual conditional expectation (ICE) plots the variations of predictive model outputs with respect to each input feature have been visualized. By using the genetic programming methodology, predictive equations have been obtained for the optimal wall thickness.

The technology known as cemented paste backfill (CPB) has gained considerable popularity worldwide. Yield stress (YS) is a significant factor considered in the assessment of CPB’s flowability or transportability. The minimal shear stress necessary to start the flow is known as Yield stress (YS), and it serves as an excellent measure of the strength of the particle-particle interaction. The traditional evaluation and measurement of YS performed by experimental tests are time-consuming and costly, which induces delays in construction projects. Moreover, the YS of CPB depends on numerous factors such as cement/tailing ratio, solid content and oxide content of tailing. Therefore, in order to simplify YS estimation and evaluation, the Artificial Intelligence (AI) approaches including eight Machine Learning techniques such as the Extreme Gradient Boosting algorithm, Gradient Boosting algorithm, Random Forest algorithm, Decision Trees, K-Nearest Neighbor, Support Vector Machine, Multivariate Adaptive Regression Splines and Gaussian Process are used to build the soft-computing model in predicting the YS of CPB. The performance of these models is evaluated by three metrics coefficient of determination (R2), Root Mean Square Error (RMSE) and Mean Absolute Error (MAE). The 3 best models were found to predict the Yield Stress of CPB (Gradient Boosting (GB), Extreme Gradient Boosting (XGB) and Random Forest (RF), respectively) with the 3 metrics of the three models, respectively, GB {R2 = 0.9811, RMSE = 0.1327 MPa, MAE = 0.0896 MPa}, XGB {R2 = 0.9034, RMSE = 0.3004 MPa, MAE = 0.1696 MPa} and RF {R2 = 0.8534, RMSE = 0.3700 MPa, MAE = 0.1786 MPa}, for the testing dataset. Based on the best performance model including GB, XG and RF, the other AI techniques such as SHapley Additive exPlanations (SHAP), Permutation Importance, and Individual Conditional Expectation (ICE) are also used for evaluating the factor effect on the YS of CPB. The results of this investigation can help the engineers to accelerate the mixed design of CPB.

Ultra-high-performance concrete (UHPC) bonded to normal concrete (NC) can significantly enhance the mechanical performance of UHPC–NC composite structures, and the interface shear strength is a crucial indicator for assessing the bonding performance. In this study, interpretable machine learning (ML) methods were used to analyse the effects of different parameters on interface shear strength. A database consisting of 305 UHPC–NC shear tests was created, and the isolation forest algorithm was applied to filter outliers. Subsequently, four ML models were trained to predict the interface shear strength of UHPC–NC composite structures. Among them, the extreme gradient boosting (XGBoost) model demonstrated the highest prediction accuracy, achieving an R2 value of 0.95. Shapley additive explanations (SHAP), partial dependence plots (PDP) and individual conditional expectation (ICE) were used for feature importance analysis, aiding in the interpretation of the ‘black box’ nature of the ML models. The results demonstrate that the normal compressive stress at the interface is the most influential factor affecting interfacial shear strength. Finally, a physically meaningful predictive equation for the interface shear strength of UHPC–NC composite structures was proposed based on the XGBoost model combined with curve fitting. This equation enhances the prediction accuracy of interface shear strength for UHPC–NC structures and offers deeper insights into the model’s decision making process.

Tree-based machine learning (ML) algorithms, such as Extra Trees (ET), Random Forest (RF), Gradient Boosting Machine (GBM), and XGBoost (XGB) are among the most widely used in early drug discovery, given their versatility and performance. However, models based on these algorithms often suffer from misclassification and reduced interpretability issues, which limit their applicability in practice. To address these challenges, several approaches have been proposed, including the use of SHapley Additive Explanations (SHAP). While SHAP values are commonly used to elucidate the importance of features driving models' predictions, they can also be employed in strategies to improve their prediction performance. Building on these premises, we propose a novel approach that integrates SHAP and features value analyses to reduce misclassification in model predictions. Specifically, we benchmarked classifiers based on ET, RF, GBM, and XGB algorithms using data sets of compounds with known antiproliferative activity against three prostate cancer (PC) cell lines (i.e., PC3, LNCaP, and DU-145). The best-performing models, based on RDKit and ECFP4 descriptors with GBM and XGB algorithms, achieved MCC values above 0.58 and F1-score above 0.8 across all data sets, demonstrating satisfactory accuracy and precision. Analyses of SHAP values revealed that many misclassified compounds possess feature values that fall within the range typically associated with the opposite class. Based on these findings, we developed a misclassification-detection framework using four filtering rules, which we termed "RAW", SHAP, "RAW OR SHAP", and "RAW AND SHAP". These filtering rules successfully identified several potentially misclassified predictions, with the "RAW OR SHAP" rule retrieving up to 21%, 23%, and 63% of misclassified compounds in the PC3, DU-145, and LNCaP test sets, respectively. The developed flagging rules enable the systematic exclusion of likely misclassified compounds, even across progressively higher prediction confidence levels, thus providing a valuable approach to improve classifier performance in virtual screening applications.

Institutional delivery dropout (IDD), defined as delivery outside a health facility despite attending antenatal care (ANC), remains a significant barrier to reducing maternal mortality in Nigeria. Traditional statistical models often fall short of capturing the complex, non-linear interactions among the socio-demographic factors that drive this critical health behavior. Using a comprehensive dataset of 16,100 women from the 2018 Nigeria Demographic and Health Survey (NDHS), we applied and compared seven diverse machine learning (ML) algorithms, including models such as Support Vector Machine (SVM), Gradient Boosting (GB), and Extreme Gradient Boosting (XGBoost). The model performance was systematically evaluated using metrics such as accuracy, Area Under the Receiver Operating Characteristic curve (AUROC), F1-score, and detailed confusion matrices. Furthermore, SHapley Additive explanations (SHAP) were used to provide transparent interpretations of feature importance and predictive contributions. Gradient Boosting was the best-performing model, achieving the highest F1-score (0.755) and AUROC (0.82). SVM achieved the highest accuracy (0.740) and recall (0.780). SHAP identified education level, household wealth, and religion as strong predictors of IDD. The performance metrics reported with confidence intervals showed modest variability across the models. Machine learning approaches were effective in identifying women at an increased risk of institutional delivery dropout. SHAP analysis provides insights into the key sociodemographic predictors of IDD, highlighting the value of interpretable ML methods in maternal health research.

To construct machine learning prediction model for sepsis-associated encephalopathy (SAE), and analyze the application value of the model on early identification of SAE risk in elderly septic patients. Patients aged over 60 years with a primary diagnosis of sepsis admitted to intensive care unit (ICU) from 2008 to 2023 were selected from Medical Information Mart for Intensive Care-IV 2.2 (MIMIC-IV 2.2). Demographic variables, disease severity scores, comorbidities, interventions, laboratory indicators, and hospitalization details were collected. Key factors associated with SAE were identified using univariate Logistic regression analysis. The data were randomly divided into training and validation sets in a 7 : 3 ratio. Multivariable Logistic regression analysis was conducted in the training set and visualized using a nomogram model for prediction of SAE. The discrimination of the model was evaluated in the validation set using the receiver operator characteristic curve (ROC curve), and its calibration was assessed using calibration curve. Furthermore, multiple machine learning algorithms, including multi-layer perceptron (MLP), support vector machine (SVM), naive bayes (NB), gradient boosting machine (GBM), random forest (RF), and extreme gradient boosting (XGB), were constructed in the training set. Their predictive performance was subsequently evaluated on the validation set. Taking the XGB model as an example, the interpretability of the model through the SHapley Additive exPlanations (SHAP) algorithm was enhanced to identify the key predictive factors and their contributions. A total of 2 204 septic patients were finally enrolled, of whom 840 developed SAE (38.1%). A total of 21 variables associated with SAE were screened through univariate Logistic regression analysis. Multivariable Logistic regression analysis showed that endotracheal intubation [odds ratio (OR) = 0.40, 95% confidence interval (95%CI) was 0.19-0.88, P < 0.001], oxygen therapy (OR = 0.76, 95%CI was 0.53-0.95, P = 0.023), tracheotomy (OR = 0.20, 95%CI was 0.07-0.53, P < 0.001), continuous renal replacement therapy (CRRT; OR = 0.32, 95%CI was 0.15-0.70, P < 0.001), cerebrovascular disease (OR = 0.31, 95%CI was 0.16-0.60, P < 0.001), rheumatic disease (OR = 0.44, 95%CI was 0.19-0.99, P < 0.001), male (OR = 0.68, 95%CI was 0.54-0.86, P = 0.001), and maximum anion gap (AG; OR = 0.95, 95%CI was 0.93-0.97, P < 0.001) were associated with an decreased probability of SAE, and age (OR = 1.05, 95%CI was 1.03-1.06, P < 0.001), acute physiology score III (APSIII; OR = 1.02, 95%CI was 1.01-1.02, P < 0.001), Oxford acute severity of illness score (OASIS; OR = 1.04, 95%CI was 1.03-1.06, P < 0.001), and length of hospital stay (OR = 1.01, 95%CI was 1.01-1.02, P < 0.001) were associated with an increased probability of SAE. A nomogram model was constructed based on these variables. In the validation set, ROC curve analysis showed that the model achieved an area under the ROC curve (AUC) of 0.723, and the calibration curve showed good consistency between the predicted probability of the model and the observed probability. Among the machine learning algorithms, including MLP, SVM, NB, GBM, RF, and XGB, the SVM model and RF model demonstrated relatively good predictive performance, with AUC of 0.748 and 0.739, respectively, and the sensitivity was both exceeding 85%. The predictive performance of the XGB model was explained through SHAP analysis, and the results indicated that APSIII score (SHAP value was 0.871), age (SHAP value was 0.521), and OASIS score (SHAP value was 0.443) were important factors affecting the predictive performance of the model. The machine learning-based SAE prediction model exhibits good predictive capability and holds significant application value for the early identification of SAE risk in elderly septic patients.

In this research work, the effect of Calcium Carbonate Filler was studied on the compressive strength and the workability of self-compacting Concrete (SCC) at different grades (M60, M65 and M70) and different coarse aggregate sizes (6.3mm, 10mm and 20mm). Calcium Carbonate Filler (Limestone powder) and Rice Husk Ash (RHA) were added in percentages of 2.5% and 5% to check its effect on the workability and strength properties of SCC and Normally Vibrated Concrete. Experimental investigations were carried out on SCC and normally vibrated concrete (NVC) samples of grade M60, M65 and M70 using different aggregate sizes of 6.3mm, 10mm and 20mm. The workability test results obtained showed values within specification. The compressive and Tensile strengths for SCC (with powder and 2.5% RHA) are higher than that with powder and 5% RHA and NVC. Generally, the use of Calcium Carbonate Filler improved the strength and densities for SCC design mix and decreased its workability. It is concluded that the use of SCC with designed Fillers ratio and RHA (?5%) will improve the strength properties of SCC.

This study focuses on using various machine learning (ML) models to evaluate the shear behaviors of ultra-high-performance concrete (UHPC) beams reinforced with glass fiber-reinforced polymer (GFRP) bars. The main objective of the study is to predict the shear strength of UHPC beams reinforced with GFRP bars using ML models. We use four different ML models: support vector machine (SVM), artificial neural network (ANN), random forest (R.F.), and extreme gradient boosting (XGBoost). The experimental database used in the study is acquired from various literature sources and comprises 54 test observations with 11 input features. These input features are likely parameters related to the composition, geometry, and properties of the UHPC beams and GFRP bars. To ensure the ML models' generalizability and scalability, random search methods are utilized to tune the hyperparameters of the algorithms. This tuning process helps improve the performance of the models when predicting the shear strength. The study uses the ACI318M-14 and Eurocode 2 standard building codes to predict the shear capacity behavior of GFRP bars-reinforced UHPC I-shaped beams. The ML models' predictions are compared to the results obtained from these building code standards. According to the findings, the XGBoost model demonstrates the highest predictive test performance among the investigated ML models. The study employs the SHAP (SHapley Additive exPlanations) analysis to assess the significance of each input parameter in the ML models' predictive capabilities. A Taylor diagram is used to statistically compare the accuracy of the ML models. This study concludes that ML models, particularly XGBoost, can effectively predict the shear capacity behavior of GFRP bars-reinforced UHPC I-shaped beams.

Chronic pain around the temporomandibular joint (TMJ) and masticatory muscles is a primary symptom of temporomandibular disorders (TMD). However, the clinical significance of magnetic resonance imaging (MRI) features in predicting TMD-related pain remains unclear. This study aimed to develop and interpret machine learning (ML) models based on MRI characteristics for predicting pain severity in patients with TMD. The present retrospective study included 584 patients with TMD between January 2022 and December 2024, yielding a total of 755 TMJ MRI data sets. Pain severity was classified using the visual analogue scale (VAS). Demographic variables (age, sex) and MRI features-including lesion side, disc position, disc morphology, disc signal, disc perforation, bilaminar zone tear, joint space, joint effusion, condylar movement, bony changes and morphology/signal of the lateral pterygoid muscle-were collected. Eleven ML models based on demographic and MRI features were developed: logistic regression (LR), support vector machine (SVM), random forest (RF), extreme gradient boosting (XGBoost), light gradient boosting machine (LightGBM), adaptive boosting (AdaBoost), gradient boosting classifier (GBC), bagging classifier (BC), extremely randomised trees (ETC), decision tree classifier (DTC) and multilayer perceptron (MLP). Model performance was evaluated using multiple metrics, including the area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity and F1 score. Precision-recall (PR) curves and calibration curves were plotted to assess discrimination and model calibration. Decision curve analysis (DCA) was conducted to evaluate the clinical net benefit across a range of threshold probabilities. Model interpretability was enhanced using Shapley Additive Explanations (SHAP), which quantified the contribution of each feature to individual predictions. Feature selection was conducted based on mean SHAP values, and separate LightGBM models were constructed using the Top 3, 5, and 9 most important features, as well as the full-feature set, for performance comparison. The data set was randomly divided into a training set (n = 604) and a test set (n = 151). Among the 11 ML models, the LightGBM model demonstrated the best predictive performance, with an AUC of 0.899, and was therefore identified as the optimal model. SHAP analysis identified age, disc position and condylar movement as the top three contributing features. Feature selection analysis indicated that selecting the top nine SHAP-ranked variables led to the highest diagnostic performance, with an AUC of 0.829. This study developed an interpretable, high-performing MRI-based ML model incorporating SHAP analysis to integrate imaging and clinical features for objective pain assessment, which may help identify high-risk TMD patients and guide personalised treatment strategies.

Although the goal of rectal cancer treatment is to restore gastrointestinal continuity, some patients with rectal cancer develop a permanent stoma (PS) after sphincter-saving operations. Although many studies have identified the risk factors and causes of PS, few have precisely predicted the probability of PS formation before surgery. To validate whether an artificial intelligence model can accurately predict PS formation in patients with rectal cancer after sphincter-saving operations. Patients with rectal cancer who underwent a sphincter-saving operation at Taipei Medical University Hospital between January 1, 2012, and December 31, 2021, were retrospectively included in this study. A machine learning technique was used to predict whether a PS would form after a sphincter-saving operation. We included 19 routinely available preoperative variables in the artificial intelligence analysis. To evaluate the efficiency of the model, 6 performance metrics were utilized: accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and area under the receiving operating characteristic curve. In our classification pipeline, the data were randomly divided into a training set (80% of the data) and a validation set (20% of the data). The artificial intelligence models were trained using the training dataset, and their performance was evaluated using the validation dataset. Synthetic minority oversampling was used to solve the data imbalance. A total of 428 patients were included, and the PS rate was 13.6% (58/428) in the training set. The logistic regression (LR), Gaussian Naïve Bayes (GNB), Extreme Gradient Boosting (XGB), Gradient Boosting (GB), random forest, decision tree and light gradient boosting machine (LightGBM) algorithms were employed. The accuracies of the logistic regression (LR), Gaussian Naïve Bayes (GNB), Extreme Gradient Boosting (XGB), Gradient Boosting (GB), random forest (RF), decision tree (DT) and light gradient boosting machine (LightGBM) models were 70%, 76%, 89%, 93%, 95%, 79% and 93%, respectively. The area under the receiving operating characteristic curve values were 0.79 for the LR model, 0.84 for the GNB, 0.95 for the XGB, 0.95 for the GB, 0.99 for the RF model, 0.79 for the DT model and 0.98 for the LightGBM model. The key predictors that were identified were the distance of the lesion from the anal verge, clinical N stage, age, sex, American Society of Anesthesiologists score, and preoperative albumin and carcinoembryonic antigen levels. Integration of artificial intelligence with available preoperative data can potentially predict stoma outcomes after sphincter-saving operations. Our model exhibited excellent predictive ability and can improve the process of obtaining informed consent.

Objective: This study aims to utilize an explainable machine learning framework to identify and rank the critical protective factors that buffer against the deleterious effects of specific childhood trauma subtypes on adolescent resilience within low-socioeconomic Iraqi contexts. Methods and Materials: A cross-sectional design was employed with a sample of adolescents (mean age years; female) from low-socioeconomic districts in Iraq. Data were collected using culturally adapted and validated instruments, including the Childhood Trauma Questionnaire-Short Form (CTQ-SF), the Connor-Davidson Resilience Scale (CD-RISC), and the Resilience Scale for Adolescents (READ). To analyze the complex, non-linear relationships between variables, an eXtreme Gradient Boosting (XGBoost) machine learning model was developed. The model’s interpretability was enhanced using SHapley Additive exPlanations (SHAP) to calculate the global predictive importance and interaction effects of specific risk and protective factors. Findings: The XGBoost model demonstrated robust predictive performance, explaining a significant portion of the variance in adolescent resilience ( , ). SHAP value analysis revealed that Family Cohesion emerged as the paramount protective factor (SHAP ), while Emotional Abuse (SHAP ) and Emotional Neglect (SHAP ) were identified as the most detrimental risk factors, surpassing physical and sexual abuse in predictive weight. Furthermore, a critical non-linear threshold effect was discovered: the protective utility of peer support increased significantly only when emotional neglect scores were below a specific clinical threshold (CTQ-SF ). Conclusion: Explainable machine learning provides granular insights into trauma recovery, highlighting that emotional maltreatment profoundly damages adolescent adaptation. Interventions in low-resource settings must prioritize systemic family-based therapies to foster cohesion and adopt a phased clinical approach that addresses foundational emotional neglect before introducing peer-based support systems.

Semiconductor Multivariate Time-Series Anomaly Classification based on Machine Learning Ensemble Techniques*

The accurate prediction of the residual strength of defective pipelines is a critical prerequisite for ensuring the safe operation of oil and gas pipelines, and it holds significant implications for the pipeline’s remaining service life and preventive maintenance. Traditional machine learning algorithms often fail to comprehensively account for the correlative factors influencing the residual strength of defective pipelines, exhibit limited capability in extracting nonlinear features from data, and suffer from insufficient predictive accuracy. Furthermore, the predictive models typically lack interpretability. To address these issues, this study proposes a hybrid prediction model for the residual strength of defective pipelines based on Bayesian optimization (BO) and eXtreme Gradient Boosting (XGBoost). This approach resolves the issues of excessive iterations and high computational costs associated with conventional hyperparameter optimization methods, significantly enhancing the model’s predictive performance. The model’s prediction performance is evaluated using mainstream metrics such as the Mean Absolute Percentage Error (MAPE), Coefficient of Determination (R2), Root Mean Square Error (RMSE), robustness analysis, overfitting analysis, and grey relational analysis. To enhance the interpretability of the model’s predictions, reveal the significance of features, and confirm prior domain knowledge, Shapley additive explanations (SHAP) are employed to conduct the relevant research. The results indicate that, compared with Random Forest, LightGBM, Support Vector Machine, gradient boosting regression tree, and Multi-Layer Perceptron, the BO-XGBoost model exhibits the best prediction performance, with MAPE, R2, and RMSE values of 5.5%, 0.971, and 1.263, respectively. Meanwhile, the proposed model demonstrates the highest robustness, the least tendency for overfitting, and the most significant grey relation degree value. SHAP analysis reveals that the factors influencing the residual strength of defective pipelines, ranked in descending order of importance, are defect depth (d), wall thickness (t), yield strength (σy), external diameter (D), defect length (L), tensile strength (σu), and defect width (w). The development of this model contributes to improving the integrity management of oil and gas pipelines and provides decision support for the intelligent management of defective pipelines in oil and gas fields.

BackgroundThis study aims to develop a advanced machine learning model to predict the fall risk among community-dwelling elders. This study could present actionable advices for early prevention of fall risk.MethodsBetween October and December 2022, 977 older adults from the Hannan District of Wuhan were recruited. Data was collected using structured questionnaires. The sample was randomly split into training (732 participants) and testing (245 participants) sets at a 3:1 ratio. The primary outcome was the occurrence of fall. Five machine learning models—Random Forest (RF), Gradient Boosted Decision Tree (GBDT), Light Gradient Boosting Machine (LGBM), Extreme Gradient Boosting (XGBoost), and Categorical Features Gradient Boosting (CatBoost)—were evaluated against a Logistic Regression (LR) model. Model performance was assessed using AUC, accuracy, precision, sensitivity, specificity, and F1 score.ResultsAmong the 977 older adults, 195 experienced falls (20.0%). ROC curve analysis showed AUC values of LR, RF, LGBM, GBDT, XGBoost, and CatBoost were, respectively, 0.8390, 0.8632, 0.8614, 0.8544, 0.8705, and 0.8719. CatBoost had the highest AUC, indicating the best predictive performance. SHapley Additive exPlanations (SHAP) analysis identified key features influencing the CatBoost model: history of falls, comorbidities, polypharmacy, sleep disorders, ADL, TUG results, frailty status, and use of assistive devices.ConclusionThe fall risk prediction model for community-dwelling older adults, developed with CatBoost, showed excellent performance and can aid in early clinical assessment and fall prevention.

Breast cancer continues to be a leading cause of death among women in the world. The prediction of survival outcomes based on treatment modalities, i.e., chemotherapy, hormone therapy, surgery, and radiation therapy is an essential step towards personalization in treatment planning. However, Machine Learning (ML) models may improve these predictions by investigating intricate relationships between clinical variables and survival. This study investigates the performance of several ML models to predict survival rate in patients undergoing diverse breast cancer treatments i.e., chemotherapy, hormone therapy, surgery and radiation using multiple clinical parameters. The dataset consisted of 5000 samples and turned into downloaded from Kaggle. The models assessed blanketed Support Vector Machines (SVM), K-Nearest Neighbor (KNN), AdaBoost, Gradient Boosting, Random Forest, Gaussian Naive Bayes, Logistic Regression, Extreme Gradient Boosting (XG boost), and Decision tree. Performance of the models was assessed using parameters such as Accuracy, Precision, Recall, F1-Score and Area under the Receiver Operating Characteristic Curve (AUC-ROC). SHAP (SHapley Additive exPlanations) values analysis was done to provide an explanation for the impact of a feature on model predictions using Waterfall and Beeswarm plots. Anticipated baseline (E(f(x))) were in comparison to the predictions (f(x)) for each therapy group. Performance of Gradient Boosting was shown to be the best with an Accuracy: 0.972, Precision: 0.973, Recall: 0.972, F1-Score: 0.973, and AUC-ROC Score: 0.997. Chemotherapy had a notably bad impact on survival, with an f(x) of -0.274 and an E(f(x)) of -0.025. Hormone therapy showed the maximum detrimental effect on survival, with an f(x) of -0.408. Surgical operation had an extraordinarily impartial impact (f(x) = -0.041), even as radiation therapy positively impacted survival results with an f(x) of 0.22. Gradient Boosting was the most predictive algorithm for breast cancer survival outcomes. This SHAP-primarily based analysis provides a complete knowledge of ways one-of-a-kind treatments have an effect on survival predictions in breast cancer patients. Radiation therapy indicates the most tremendous effect on survival, whilst hormone therapy reveals the maximum poor effect. Future studies need to explore personalized treatment strategies that comprise these insights to enhance patient effects.