Machine learning and deep learning approach for medical image analysis: diagnosis to detection

Millions of people worldwide suffer from Parkinson’s disease (PD), a neurodegenerative disorder marked by motor symptoms such as tremors, bradykinesia, and stiffness. Accurate early diagnosis is crucial for effective management and treatment. This article presents a novel review of Machine Learning (ML) and Deep Learning (DL) techniques for PD detection and progression monitoring, offering new perspectives by integrating diverse data sources. We examine the public datasets recently used in studies, including audio recordings, gait analysis, and medical imaging. We discuss the preprocessing methods applied, the state-of-the-art models utilized, and their performance. Our evaluation included different algorithms such as support vector machines (SVM), random forests (RF), convolutional neural networks (CNN). These algorithms have shown promising results in PD diagnosis with accuracy rates exceeding 99% in some studies combining data sources. Our analysis particularly showcases the effectiveness of audio analysis in early symptom detection and gait analysis, including the Unified Parkinson’s Disease Rating Scale (UPDRS), in monitoring disease progression. Medical imaging, enhanced by DL techniques, has improved the identification of PD. The application of ML and DL in PD research offers significant potential for improving diagnostic accuracy. However, challenges like the need for large and diverse datasets, data privacy concerns, and data quality in healthcare remain. Additionally, developing explainable AI is crucial to ensure that clinicians can trust and understand ML and DL models. Our review highlights these key challenges that must be addressed to enhance the robustness and applicability of AI models in PD diagnosis, setting the groundwork for future research to overcome these obstacles.

Coastal aquifers are vital for sustaining ecosystems and providing freshwater for agriculture and domestic use. However, rising groundwater salinity in these regions demands innovative approaches for accurate modeling and prediction. In recent decades, machine learning (ML) and deep learning (DL) techniques have been extensively used across various water resource management fields, often yielding promising outcomes. This review examines the growing usage of ML and DL techniques in modeling groundwater salinity in coastal aquifers. The analysis is based on 104 peer-reviewed journal articles including the review articles indexed in PubMed, ScienceDirect, Google Scholar, Scopus, and SpringerLink using keywords like "saltwater intrusion", "machine learning", “deep learning”, and "groundwater salinity". The review discusses recent advancements, challenges, and future directions for improving ML model accuracy and applicability. Studies reveal an increasing reliance on ML techniques to predict groundwater salinity and manage seawater intrusion across various coastal geological settings. Researchers have employed a range of ML models, from traditional methods like Artificial Neural Networks and Adaptive Neuro Fuzzy Inference Systems to advanced DL-based models like Convolutional Neural Networks and Long Short-Term Memory Networks, often using ensemble methods to enhance accuracy. Key findings include the top-tier output of ensemble and optimized models, including Random Forest and Grasshopper Optimization Algorithm-XGBoost. These studies highlight the importance of model selection, input variable ranking, and computational efficiency, demonstrating ML's global relevance in environmental management. The review highlights the prospects of ML, DL, and ensemble models to redefine groundwater management in coastal aquifers, offering more effective and sustainable solutions to the challenges posed by groundwater salinity and saltwater intrusion. Future advancements will focus on further integrating DL, explainable artificial intelligence, and ensemble approaches, along with other innovative techniques, to explore sparsely studied variables, model new or unique study areas, and apply ML methods for managing groundwater salinity.

Deep and machine learning techniques for medical imaging-based breast cancer: A comprehensive review

COVID-19 is highly infectious and causes acute respiratory disease. Machine learning (ML) and deep learning (DL) models are vital in detecting disease from computerized chest tomography (CT) scans. The DL models outperformed the ML models. For COVID-19 detection from CT scan images, DL models are used as end-to-end models. Thus, the performance of the model is evaluated for the quality of the extracted feature and classification accuracy. There are four contributions included in this work. First, this research is motivated by studying the quality of the extracted feature from the DL by feeding these extracted to an ML model. In other words, we proposed comparing the end-to-end DL model performance against the approach of using DL for feature extraction and ML for the classification of COVID-19 CT scan images. Second, we proposed studying the effect of fusing extracted features from image descriptors, e.g., Scale-Invariant Feature Transform (SIFT), with extracted features from DL models. Third, we proposed a new Convolutional Neural Network (CNN) to be trained from scratch and then compared to the deep transfer learning on the same classification problem. Finally, we studied the performance gap between classic ML models against ensemble learning models. The proposed framework is evaluated using a CT dataset, where the obtained results are evaluated using five different metrics The obtained results revealed that using the proposed CNN model is better than using the well-known DL model for the purpose of feature extraction. Moreover, using a DL model for feature extraction and an ML model for the classification task achieved better results in comparison to using an end-to-end DL model for detecting COVID-19 CT scan images. Of note, the accuracy rate of the former method improved by using ensemble learning models instead of the classic ML models. The proposed method achieved the best accuracy rate of 99.39%.

Artificial intelligence (AI)-based approaches are crucial in computer-aided diagnosis (CAD) for various medical applications. Their ability to quickly and accurately learn from complex data is remarkable. Deep learning (DL) models have shown promising results in accurately classifying Alzheimer's disease (AD) and its related cognitive states, Early Mild Cognitive Impairment (EMCI) and Late Mild Cognitive Impairment (LMCI), along with the healthy conditions known as Cognitively Normal (CN). This offers valuable insights into disease progression and diagnosis. However, certain traditional machine learning (ML) classifiers perform equally well or even better than DL models, requiring less training data. This is particularly valuable in CAD in situations with limited labeled datasets. In this paper, we propose an ensemble classifier based on ML models for magnetic resonance imaging (MRI) data, which achieved an impressive accuracy of 96.52%. This represents a 3-5% improvement over the best individual classifier. We evaluated popular ML classifiers for AD classification under both data-scarce and data-rich conditions using the Alzheimer's Disease Neuroimaging Initiative and Open Access Series of Imaging Studies datasets. By comparing the results to state-of-the-art CNN-centric DL algorithms, we gain insights into the strengths and weaknesses of each approach. This work will help users to select the most suitable algorithm for AD classification based on data availability.

PurposeThe first transmission of coronavirus to humans started in Wuhan city of China, took the shape of a pandemic called Corona Virus Disease 2019 (COVID-19), and posed a principal threat to the entire world. The researchers are trying to inculcate artificial intelligence (Machine learning or deep learning models) for the efficient detection of COVID-19. This research explores all the existing machine learning (ML) or deep learning (DL) models, used for COVID-19 detection which may help the researcher to explore in different directions. The main purpose of this review article is to present a compact overview of the application of artificial intelligence to the research experts, helping them to explore the future scopes of improvement.MethodsThe researchers have used various machine learning, deep learning, and a combination of machine and deep learning models for extracting significant features and classifying various health conditions in COVID-19 patients. For this purpose, the researchers have utilized different image modalities such as CT-Scan, X-Ray, etc. This study has collected over 200 research papers from various repositories like Google Scholar, PubMed, Web of Science, etc. These research papers were passed through various levels of scrutiny and finally, 50 research articles were selected.ResultsIn those listed articles, the ML / DL models showed an accuracy of 99% and above while performing the classification of COVID-19. This study has also presented various clinical applications of various research. This study specifies the importance of various machine and deep learning models in the field of medical diagnosis and research.ConclusionIn conclusion, it is evident that ML/DL models have made significant progress in recent years, but there are still limitations that need to be addressed. Overfitting is one such limitation that can lead to incorrect predictions and overburdening of the models. The research community must continue to work towards finding ways to overcome these limitations and make machine and deep learning models even more effective and efficient. Through this ongoing research and development, we can expect even greater advances in the future.

Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis, contributing to a heavier global health burden. Non-invasive diagnostic tools developed using machine learning (ML) and deep learning (DL), two representative artificial intelligence algorithms, are increasingly being explored for MASH and its related fibrosis assessment. This study aimed to compare the diagnostic performance of different ML and DL models and identify the top-performing models for diagnosing MASH and associated liver fibrosis. A systematic review and meta-analysis were conducted across PubMed, Web of Science, Embase and Cochrane Library from inception to May 18, 2025. Pooled area under the receiver operator characteristic curve (AUROC) values with 95 % confidence interval (CI) were calculated. Accuracy, specificity, sensitivity, positive predictive values, and negative predictive values were also recorded. Of 4,314 studies initially identified, 106 met the inclusion criteria, with 35 studies (ML: n=28; DL: n=7) providing data for analysis. Logistic Regression and Neural Network are the most commonly algorithms applied in ML and DL, respectively. The pooled AUROCs for diagnosing MASH were 0.833 (95 %CI: 0.806-0.860) for ML models and 0.841 (95 %CI: 0.782-0.900) for DL models. Light Gradient Boosting Machine (LightGBM) and ResNet50 were the best-performing models for diagnosing MASH within ML and DL algorithms, respectively, achieving corresponding AUROCs of 0.920 (95 %CI: 0.916-0.924) and 0.960 (95 %CI: 0.951-0.969). For fibrosis diagnosis, ML models had a pooled AUROC of 0.826 (95 %CI: 0.792-0.860), with Categorical Boosting (CatBoost) achieving the highest AUROC of 0.960 (95 %CI: 0.950-0.970). DL models yielded the pooled AUROC of 0.875 (95 %CI: 0.816-0.934) for fibrosis diagnosis. Both ML and DL models demonstrated strong diagnostic performance for MASH and liver fibrosis, with DL achieving marginally higher AUROCs. AI-driven approaches show promise in MASLD management.

A comprehensive review on detection of plant disease using machine learning and deep learning approaches

With the development of information and technology, especially with the boom in big data, healthcare support systems are becoming much better. Patient data can be collected, retrieved, and stored in real time. These data are valuable and meaningful for monitoring, diagnosing, and further applications in data analysis and decision-making. Essentially, the data can be divided into three types, namely, statistical, image-based, and sequential data. Each type has a different method of retrieval, processing, and deployment. Additionally, the application of machine learning (ML) and deep learning (DL) in healthcare support systems is growing more rapidly than ever. Numerous high-performance architectures are proposed to optimize decision-making. As reliability and stability are the most important factors in the healthcare support system, enhancing the predicted performance and maintaining the stability of the model are always the top priority. The main idea of our study comes from ensemble techniques. Numerous studies and data science competitions show that by combining several weak models into one, ensemble models can attain outstanding performance and reliability. We propose three deep ensemble learning (DEL) approaches, each with stable and reliable performance, that are workable on the above-mentioned data types. These are deep-stacked generalization ensemble learning, gradient deep learning boosting, and deep aggregation learning. The experiment results show that our proposed approaches achieve more vigorous and reliable performance than traditional ML and DL techniques on statistical, image-based, and sequential benchmark datasets. In particular, on the Heart Disease UCI dataset, representing the statistical type, the gradient deep learning boosting approach dominates the others with accuracy, recall, F1-score, Matthews correlation coefficient, and area under the curve values of 0.87, 0.81, 0.83, 0.73, and 0.91, respectively. On the X-ray dataset, representing the image-based type, the deep aggregation learning approach shows the highest performance with values of 0.91, 0.97, 0.93, 0.80, and 0.94, respectively. On the Depresjon dataset, representing the sequence type, the deep-stacked generalization ensemble learning approach outperforms the others with values of 0.91, 0.84, 0.86, 0.8, and 0.94, respectively. Overall, we conclude that applying DL models using our proposed approaches is a promising method for the healthcare support system to enhance prediction and diagnosis performance. Furthermore, our study reveals that these approaches are flexible and easy to apply to achieve optimal performance.

In today’s digital environment, the pattern is everywhere. It is present in many aspects of our daily life. Algorithms can be used to detect or mathematically observe a pattern physically. Vector feature values represent a pattern in the digital world. With the advent of artificial intelligence (AI) techniques in the recent era, there are so many machine learning (ML) and deep learning (DL) models that have been developed. ML is the branch of AI, which can perform tasks like data analysis, analytical model building, and classification without being explicitly programmed. DL is the subset of ML in AI. In DL, mostly artificial neural networks (ANNs) are utilized. It has the capability of work based upon unsupervised learning from the data that is unlabeled and unstructured. Using these DL and ML models, extract the meaningful features from the given image or video is known as pattern recognition (PR). PR is used in many engineering applications such as computer vision, natural language processing, character recognition, robotics, speech recognition, and so on. It is also used in many medical image processing applications and telemedicine. The present work discussed the pattern recognition problem and its various stages in detail. In addition to that, the application of deep learning and machine learning in pattern recognition is also explained briefly.

This survey paper explores the application of machine learning (ML) techniques in the domain of workplace injuries, focusing on three key areas: risk prediction, return to work (RTW) strategies, and demographic analysis. Through an extensive review of literature from January 2015 to July 2024, this paper examines the latest advancements in ML-driven approaches to workplace safety and identifies important research gaps. This paper highlights how classical ML techniques, such as ensemble models and decision trees, have become essential tools for identifying workplace injury risks, enabling more accurate interventions. It emphasizes the importance of leveraging ML in personalized RTW programs, which use data-driven insights to improve recovery outcomes and reduce economic demands. In the context of demographic analysis, this paper explores how ML algorithms can uncover disparities in injury rates across various age groups, industries, and occupations, underscoring the need for targeted safety measures. Moreover, research gaps are identified, particularly regarding the emerging potential of advanced ML techniques, such as deep learning and large language models (LLMs), for analyzing structured and unstructured safety data, methods that have not yet been widely applied in workplace injury research. As such, future research should apply recent advances in ML, integrating these approaches with comprehensive and accessible datasets to enhance the prediction and prevention of workplace injuries, provide more detailed analytics and insights, and improve safety protocols across all industries. This comprehensive survey is an invaluable resource for researchers and practitioners leveraging ML to address complex challenges in workplace safety.

In this chapter, we introduce several applications of machine learning and deep learning in different domains, including sensor and time-series, image and vision, text and natural language processing, relational data, energy, manufacturing, social media, health, security, and Internet-of-Things (IoT) applications. Until 2010, traditional ML models such as SVMs and decision trees have enjoyed successes in various tasks, including handwritten digit classification, face detection, and pattern recognition. Though traditional ML models are easy to interpret, the model’s inputs need to be well-designed, handcrafted features. On the other hand, deep learning models circumvent this problem and directly take the raw data as input and provide end-to-end learning capability. There is an unprecedented increase in machine learning and deep learning applications, especially with the emergence of fast mobile devices with access to cloud computing. While cloud computing provides the necessary computational power to train deep learning models, trained models can be easily deployed in the cloud or on embedded devices at the edge of the cloud to carry out the inference.

Multiple Sclerosis (MS) is a chronic neuroinflammatory disease of the Central Nervous System (CNS) in which the body's immune system attacks and destroys the myelin sheath that protects nerve fibers, leading to a wide range of debilitating symptoms and causing disruption of axonal signal transmission. Accurate prediction, diagnosis, monitoring and treatment (PDMT) of MS are essential to improve patient outcomes. Recent advances in neuroimaging technologies, particularly electroencephalography (EEG), combined with machine learning (ML) techniques - including Deep Learning (DL) models - offer promising avenues for enhancing MS management. This systematic review synthesizes existing research on the application of ML and DL models to EEG data for MS. It explores the methodologies used, with a focus on DL architectures such as Convolutional Neural Networks (CNNs) and hybrid models, and highlights recent advancements in ML techniques and EEG technologies that have significantly improved MS diagnosis and monitoring. The review addresses the challenges and potential biases in using ML-based EEG analysis for MS. Strategies to mitigate these challenges, including advanced preprocessing techniques, diverse training datasets, cross-validation methods, and explainable Artificial Intelligence (AI), are discussed. Finally, the paper outlines potential future applications and trends in ML for MS management. This review underscores the transformative potential of ML-enhanced EEG analysis in improving MS management, providing insights into future research directions to overcome existing limitations and further improve clinical practice.

Daily scale streamflow forecasting in multiple stream orders of Cauvery River, India: Application of advanced ensemble and deep learning models

Lung cancer remains a leading cause of global mortality, with early detection being critical for improving the patient survival rates. However, applying machine learning and deep learning effectively for lung cancer prediction using symptomatic and lifestyle data requires the careful consideration of feature selection and model optimization, which is not consistently addressed in the existing research. This research addresses this gap by systematically evaluating and comparing the predictive efficacy of several machine learning and deep learning models, employing rigorous data preprocessing, including feature selection with Pearson’s correlation, outlier removal, and normalization, on a patient symptom and lifestyle factor dataset from Kaggle. Machine learning classifiers, including Decision Trees, K-Nearest Neighbors, Random Forest, Naïve Bayes, AdaBoost, Logistic Regression, and Support Vector Machines, were implemented using Weka simultaneously with neural network models with 1, 2, and 3 hidden layers, which were developed in Python within a Jupyter Notebook environment. The model performance was assessed using K-fold cross-validation and 80/20 train/test splitting. The results highlight the importance of feature selection for enhancing the model accuracy and demonstrate that the single-hidden-layer neural network, trained for 800 epochs, achieved a prediction accuracy of 92.86%, outperforming the machine learning models. This study contributes to developing more effective computational methods for early lung cancer detection, ultimately supporting improved patient outcomes.