Pyogenic granuloma

Pyogenic granuloma (PG) is an inflammatory hyperplastic lesion of the oral cavity. The most common etiological factors for PG are low-grade local irritation, traumatic injury, or hormonal factors. Clinically, it appears to be smooth or lobulated exophytic lesion. It appears to be erythematous papule and is either pedunculated or has a sessile base. The lesion has shown a recurrence rate of 15.8%. Various treatment modalities have been present in the literature. The present article emphasized the treatment modalities and an effort to treat the recurrence of PG with the use of platelet-rich fibrin (PRF) membrane. This case report presents a 28-year-old female patient who had reported with PG that recurred twice in 2-year period. The lesion appeared to be recurrent with sessile base and was diagnosed clinically and histopathologically as PG. The PG was excised with the conventional scalpel method exposing the underlying bone. The exposed surface was then covered with PRF membrane. At 12-month follow-up period, the patient did not show any further recurrence of the lesion.

Pyogenic granuloma (PG) is hyperplastic inflammatory lesion or growth occurring due to constant irritation, traumatic injury, or hormonal factors. PG can occur on the skin and oral cavity. In the oral cavity, it most often occurs in the gingiva. Other oral sites involved are buccal mucosa, lip, tongue, and palate. Histopathological examination is crucial for its accurate diagnosis as it can be misdiagnosed due to its clinical resemblance with peripheral ossifying fibroma, peripheral giant cell granuloma, hemangioma, and fibroma. Here, we present a case of an 18-year-old male having a lesion in the mandible anterior region in the lingual aspect of the gingiva.

Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low- grade local irritation, traumatic injury or hormonal factors. The clinical diagnosis of such lesion can be quite challenging because of its close resemblance to certain malignancies like peripheral giant cell granuloma, kaposi’s sarcoma, non hodgkin’s lymphoma etc. for excisional biopsy, options available are conventional surgical excision, electrocautery or lasers. In this report, we seek to highlight the therapeutic advantages achieved with a soft tissue diode laser in the treatment of pyogenic granuloma.

Pyogenic granuloma is one of the inflammatory hyperplasias seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion Conservative surgical excision is usually curative but recurrence is not unusual. Lasers and cryotherapy may also be employed.

Pyogenic granuloma (PG), more accurately known as lobular capillary hemangioma, is a benign vascular tumor that usually occurs in the skin or oral mucosa. This lesion is rarely reported in the gastrointestinal tract but is known to bleed if not resected. We herein describe a case series with the clinical, endoscopic, and histologic findings of four cases of gastrointestinal PG at our institution. In addition, we provide a review of the literature and summation of all reported cases of PG specific to the gastrointestinal tract. Based on our experience, we suggest that the actual incidence of gastrointestinal PG may in fact be higher than reported because PG can be unrecognized or improperly diagnosed. It is important for the clinician to properly recognize this lesion as a source of anemia and its propensity to bleed during biopsy or resection.

Pyogenic Granuloma: a Case Report

Pyogenic granuloma is one of the inflammatory hyperplasia seen in the oral cavity. It usually arises in response to various stimuli such as low-grade local irritation, traumatic injury, hormonal factors, or certain kinds of drugs. Clinically oral pyogenic granuloma is seen as a smooth exophytic lesion with usually hemorrhagic base. The surface presents from pink to red to purple. This case report describes a pyogenic granuloma in a 32-year-old female patient, discussing the clinical features and histopathologic features that distinguish this lesion from other similar oral mucosa lesions and also the successful management of the lesion.

An uncommon diagnosis behind a common respiratory symptom: Lobular capillary hemangioma of the trachea in a pediatric patient.

Pyogenic granuloma is a nonneoplastic inflammatory reactive hyperplasia commonly found in the soft tissues of the skin and oral mucosa. Oral pyogenic granulomas are usually found on the lips, gingiva, and tongue, but rarely on the palate. Surgical excision is the standard treatment for oral pyogenic granulomas. If it occurs on the palate, it is important to differentiate it from salivary gland tumors. Additionally, managing the disease with attention to recurrence is important. In this report, we present the case of a 66-year-old man who presented to the Department of Oral Diagnosis and Medicine at Hokkaido University Hospital with a mass lesion between the soft and hard palates. The patient was followed up for one year, but the lesion gradually enlarged and was accompanied by hemorrhage. Because of the atypical clinical course of the lesion, it was excised with a 7 mm safety margin, considering the possibility of palatal malignancy. Histopathological examination revealed oral pyogenic granuloma. When treating palatal tumors, clinicians should consider the possibility of minor salivary gland tumors, including malignancies.

Pyogenic granulomas are benign vascular tumours usually surgically treated by excision or curettage. The only topical therapy reported to date is imiquimod 5% cream but it produces a marked inflammatory response with discomfort generally worse than simple surgical excision or curettage. Here we report the use of timolol 0·5% ophthalmic gel used successfully to treat a teenager with a clinically classical pyogenic granuloma on the finger. There were no reported adverse effects and the lesion completely resolved. It has not recurred after 7 months. Timolol may be an effective and preferable alternative treatment to surgery for a classical small pyogenic granuloma, particularly in children and young people.

Purpose: The purpose of this study is to evaluate the treatment and pursuit process of the pyogenic granuloma which has seen on 12 years old girl patient. Case Presentation: Pyogenic granuloma is a lesion which classified in vascular tumors which constitute 30-60% of all the reactive lesions of gingival tissue. Trauma, infections of capillary wall, hormonal factors, foreign materials, hypertension and poor oral hygiene are accused for development of pyogenic granuloma. It may occur at all age groups and in both sexs. In the oral cavity, pyogenic granuloma lesions are most frequently encountered on the gingiva. Definitive diagnosis can only be made by histopathologic examination of biopsied tissue. The treatment of this lesion is surgical excision. If surgical excision removal is incomplete, the lesion has got the risk of the recurrence. A twelve years old female child applied to our clinic with complaints like on anterior palatinal region gingival bleeding and swollen condition on the same region. As beginning treatment oral hygiene education was given to the patient and plaque and calculus were removed. Under local anesthesia the lesion was taken with excisional biopsy for doing distinctive diagnosis from the other pathological lesions which can be seen in oral cavity. In addition frenectomy surgery in the maxilla and ridge augmentation operation in the mandible is performed to provide more comfortable oral hygiene. Three-month follow-up results of the patients were found to occur again in the region of the palatal gingival enlargement. As a result, it was decided to re-operations performed gingivectomy. Patient after operations carried out gingivectomy was called to the appointment checked and encourage oral hygiene. Conclusion: After taking of the excisional biopsy, the diagnose was made shaping “The Pyogenic Granuloma” to the mass which was examined histopathologically under the light microscope. In the control inspection, there was not any recurrence clinically. Keywords: Pyogenic granuloma, excisional biopsy.

Objective To explore the chnical manifestation,pathological features and characteristics of lobular capillary hemangioma (LCH),so as to raise awareness.Methods Sixty-nine cases of LCH were studied by routine histopathologic and immunohistochemical examinations.Results The age range of the 69 patients including 34 males and 35 females with LCH was 4-80 years,with an average age of 42 years.The lesions of 50 cases were located in head and neck region,and the other 19 cases were in other parts of the body,with 1 case in the left main bronchus and intracalvarium.The average diameter of the tumors was about 1 cm,and parts of the tumors showed polypoid masses.Most of the tumors were in the skin and mucosa.Granulomatous lesions showed the proliferation of thin-walled and thick-walled capillaries in a lobular pattern.The vascular interstitium was edematous and was infiltrated by the inflammatory cells.Immunohistochemical examination showed CD34 positive in the endothelial cells and smooth muscle actin positive in the peri-vascular spindle cells.Conclusions Studies of LCH show the obvious features on age,gender and diseased location,and very few have a relapse.Its pathogenesis is still unclear.LCH is rarely found in the trachea,and is more rarely in the central nervous system.So far,there is no case report to show LCH occurs both in the bronchus and intracalvarium.In the special case,the early lesion is found in the left main bronchus.Although the patient is treated,LCH still recurs for many times in a short period.Finally the tumor is also found in the intracalvarium.Therefore,it's critical to alert whether LCH also occurs in the important organs at the early stage.Complete surgical resection and / or adjuvant radiotherapy can avoid delaying the treatment and the subsequent serious outcomes. Key words: Hemangioma,capillary; Granulation tissue; Bronchi

Pyogenic granulomas are cmmon benign tumors which generally occur in the head and neck region. The most common site of occureence is the gingival of the oral cavity. Trauma and hormone imbalance have been proposed as etiologies. Oral pyogenic granulomas are usually small because the patients themselves can easily detec these lesions. We report the case of a 54-year-old mentally retarded woman who presented with a large oral tumor on her hard palate. This 5*4cm cauliflower-like pink tumor was firm with a pedicle originating from the dental socket of her left upper molar. It was excised and the gingival defect was covered with a local rotational palatal flap. The histopathology revealed a pyogenic granuloma with extensive fibrosis, indicating a long-term process. She has received follow-up examination for 3 years with no recurrence of the tumor. Large oral pyogenic granulomas are unusual and should be considered in the differential diagnosis of a malignant oral tumor. Complete surgical removal of the tumor and subsequent convering of the area with a local palatal flap can prevent recurrene. (Tzu Chi Med J1998;10:145-149)

To present a case report of extragingival pyogenic granuloma on lower lip which is an uncommon site for pathological entity and also to emphasize the reason for its occurrence. Pyogenic granuloma (PG) is a benign vascular neoplasm more often appear as lobulated or smooth red nodular lesion commonly in gingiva. Extragingival occurrence of PG is very rare. The present article reports a rare case of 55-year-old female with PG presenting rapid growing mass on the lower lip. This article highlights the possibility on the reason for its occurrence which is important for the diagnosis in this atypical location. The primary etiology of lower lip lesion is trauma and contributory factors being poor oral hygiene and betel quid chewing. Pyogenic granuloma is one of the common lesions in oral cavity. This article highlights the pyogenic granuloma on lip which is an unusual site. Although it can be diagnosed clinically, atypical presentations lead to inappropriate diagnosis. Therefore, further investigation by biopsy confirms final diagnosis upon which treatment is instituted.

Lobular capillary haemangioma, also known as pyogenic granuloma, is a benign vascular tumour that usually originates in the skin and mucosal membrane. It sometimes derives from the lumen of a...