Seismic Data Analysis with Deep Learning Models: Methods, Applications, and Future Perspectives

PurposeTo conduct a head-to-head comparison between deep learning (DL) and radiomics models across institutions for predicting microvascular invasion (MVI) in hepatocellular carcinoma (HCC) and to investigate the model robustness and generalizability through rigorous internal and external validation.MethodsThis retrospective study included 2304 preoperative images of 576 HCC lesions from two centers, with MVI status determined by postoperative histopathology. We developed DL and radiomics models for predicting the presence of MVI using B-mode ultrasound, contrast-enhanced ultrasound (CEUS) at the arterial, portal, and delayed phases, and a combined modality (B + CEUS). For radiomics, we constructed models with enlarged vs. original regions of interest (ROIs). A cross-validation approach was performed by training models on one center’s dataset and validating the other, and vice versa. This allowed assessment of the validity of different ultrasound modalities and the cross-center robustness of the models. The optimal model combined with alpha-fetoprotein (AFP) was also validated. The head-to-head comparison was based on the area under the receiver operating characteristic curve (AUC).ResultsThirteen DL models and 25 radiomics models using different ultrasound modalities were constructed and compared. B + CEUS was the optimal modality for both DL and radiomics models. The DL model achieved AUCs of 0.802–0.818 internally and 0.667–0.688 externally across the two centers, whereas radiomics achieved AUCs of 0.749–0.869 internally and 0.646–0.697 externally. The radiomics models showed overall improvement with enlarged ROIs (P < 0.05 for both CEUS and B + CEUS modalities). The DL models showed good cross-institutional robustness (P > 0.05 for all modalities, 1.6–2.1% differences in AUC for the optimal modality), whereas the radiomics models had relatively limited robustness across the two centers (12% drop-off in AUC for the optimal modality). Adding AFP improved the DL models (P < 0.05 externally) and well maintained the robustness, but did not benefit the radiomics model (P > 0.05).ConclusionCross-institutional validation indicated that DL demonstrated better robustness than radiomics for preoperative MVI prediction in patients with HCC, representing a promising solution to non-standardized ultrasound examination procedures.

COVID-19 is highly infectious and causes acute respiratory disease. Machine learning (ML) and deep learning (DL) models are vital in detecting disease from computerized chest tomography (CT) scans. The DL models outperformed the ML models. For COVID-19 detection from CT scan images, DL models are used as end-to-end models. Thus, the performance of the model is evaluated for the quality of the extracted feature and classification accuracy. There are four contributions included in this work. First, this research is motivated by studying the quality of the extracted feature from the DL by feeding these extracted to an ML model. In other words, we proposed comparing the end-to-end DL model performance against the approach of using DL for feature extraction and ML for the classification of COVID-19 CT scan images. Second, we proposed studying the effect of fusing extracted features from image descriptors, e.g., Scale-Invariant Feature Transform (SIFT), with extracted features from DL models. Third, we proposed a new Convolutional Neural Network (CNN) to be trained from scratch and then compared to the deep transfer learning on the same classification problem. Finally, we studied the performance gap between classic ML models against ensemble learning models. The proposed framework is evaluated using a CT dataset, where the obtained results are evaluated using five different metrics The obtained results revealed that using the proposed CNN model is better than using the well-known DL model for the purpose of feature extraction. Moreover, using a DL model for feature extraction and an ML model for the classification task achieved better results in comparison to using an end-to-end DL model for detecting COVID-19 CT scan images. Of note, the accuracy rate of the former method improved by using ensemble learning models instead of the classic ML models. The proposed method achieved the best accuracy rate of 99.39%.

Electricity load forecasting is a crucial undertaking within all the deregulated markets globally. Among the research challenges on a global scale, the investigation of deep transfer learning (DTL) in the field of electricity load forecasting represents a fundamental effort that can inform artificial intelligence applications in general. In this paper, a comprehensive study is reported regarding day-ahead electricity load forecasting. For this purpose, three sequence-to-sequence (Seq2seq) deep learning (DL) models are used, namely the multilayer perceptron (MLP), the convolutional neural network (CNN) and the ensemble learning model (ELM), which consists of the weighted combination of the outputs of MLP and CNN models. Also, the study focuses on the development of different forecasting strategies based on DTL, emphasizing the way the datasets are trained and fine-tuned for higher forecasting accuracy. In order to implement the forecasting strategies using deep learning models, load datasets from three Greek islands, Rhodes, Lesvos, and Chios, are used. The main purpose is to apply DTL for day-ahead predictions (1–24 h) for each month of the year for the Chios dataset after training and fine-tuning the models using the datasets of the three islands in various combinations. Four DTL strategies are illustrated. In the first strategy (DTL Case 1), each of the three DL models is trained using only the Lesvos dataset, while fine-tuning is performed on the dataset of Chios island, in order to create day-ahead predictions for the Chios load. In the second strategy (DTL Case 2), data from both Lesvos and Rhodes concurrently are used for the DL model training period, and fine-tuning is performed on the data from Chios. The third DTL strategy (DTL Case 3) involves the training of the DL models using the Lesvos dataset, and the testing period is performed directly on the Chios dataset without fine-tuning. The fourth strategy is a multi-task deep learning (MTDL) approach, which has been extensively studied in recent years. In MTDL, the three DL models are trained simultaneously on all three datasets and the final predictions are made on the unknown part of the dataset of Chios. The results obtained demonstrate that DTL can be applied with high efficiency for day-ahead load forecasting. Specifically, DTL Case 1 and 2 outperformed MTDL in terms of load prediction accuracy. Regarding the DL models, all three exhibit very high prediction accuracy, especially in the two cases with fine-tuning. The ELM excels compared to the single models. More specifically, for conducting day-ahead predictions, it is concluded that the MLP model presents the best monthly forecasts with MAPE values of 6.24% and 6.01% for the first two cases, the CNN model presents the best monthly forecasts with MAPE values of 5.57% and 5.60%, respectively, and the ELM model achieves the best monthly forecasts with MAPE values of 5.29% and 5.31%, respectively, indicating the very high accuracy it can achieve.

We developed a multimodal ultrasound (US) deep learning (DL) fusion model to automatically classify early fibrosis in patients with chronic kidney disease (CKD). This prospective study included patients with CKD who underwent continuous gray-scale US, superb microvascular imaging, and strain elastography from May to November 2022. According to the pathological tubular atrophy and interstitial fibrosis score, patients were divided into minimal and mild groups (affected area ≤10% and 11 − 25% of the total cortical volume, respectively). The dataset was divided into training (70%) and test (30%) sets. A DL model combining the features of the three US modes was developed to predict early fibrosis in patients with CKD. We compared these findings with the area under the receiver operating characteristic curve (AUC) of the clinical model by analyzing the receiver operating characteristic curve in the test set. The AUC of single-mode DL based on gray-scale US, superb microvascular imaging, and strain elastography was 0.682, 0.745, and 0.648, respectively, while that of the multimodal US DL model was 0.86. The accuracy, specificity, and sensitivity of the multimodal US DL model were 0.779, 0.767, and 0.796, respectively, and the negative and positive predictive values were 0.842 and 0.706, respectively. The AUC of the multimodal US DL model was significantly better than that of the single-mode DL and clinical models. The DL algorithm developed using multimodal US images can effectively predict early fibrosis in patients with CKD with significantly greater accuracy than single-mode DL or clinical models.

We aimed at comparing intratumoral and peritumoral deep learning, radiomics, and fusion models in predicting KRAS mutations in rectal cancer using endorectal ultrasound imaging. This study included 304 patients with rectal cancer from Fujian Medical University Union Hospital. The patients were randomly divided into a training group (213 patients) and a test group (91 patients) at a 7:3 ratio. Radiomics and deep learning models were established using primary tumor and peritumoral images. In the optimally performing regions-of-interest, two fusion strategies, a feature-based and a decision-based model, were employed to build the fusion models. The Shapley additive explanation (SHAP) method was used to evaluate the significance of features in the optimal radiomics, deep learning, and fusion models. The performance of each model was assessed using the area under the receiver operating characteristic curve (AUC) and decision curve analysis (DCA). In the test cohort, both the radiomics and deep learning models exhibited optimal performance with a 10-pixel patch extension, yielding AUC values of 0.824 and 0.856, respectively. The feature-based DLRexpand10_FB model attained the highest AUC (0.896) across all study sets. In addition, the DLRexpand10_FB model demonstrated excellent sensitivity, specificity, and DCA. SHAP analysis underscored the deep learning feature (DL_1) as the most significant factor in the hybrid model. The feature-based fusion model DLRexpand10_FB can be employed to predict KRAS gene mutations based on pretreatment endorectal ultrasound images of rectal cancer. The integration of peritumoral regions enhanced the predictive performance of both the radiomics and deep learning models.

Deep learning breast cancer risk models demonstrate improved accuracy compared with traditional risk models but have not been prospectively tested. We compared the accuracy of a deep learning risk score derived from the patient's prior mammogram to traditional risk scores to prospectively identify patients with cancer in a cohort due for screening. We collected data on 119 139 bilateral screening mammograms in 57 617 consecutive patients screened at 5 facilities between September 18, 2017, and February 1, 2021. Patient demographics were retrieved from electronic medical records, cancer outcomes determined through regional tumor registry linkage, and comparisons made across risk models using Wilcoxon and Pearson χ2 2-sided tests. Deep learning, Tyrer-Cuzick, and National Cancer Institute Breast Cancer Risk Assessment Tool (NCI BCRAT) risk models were compared with respect to performance metrics and area under the receiver operating characteristic curves. Cancers detected per thousand patients screened were higher in patients at increased risk by the deep learning model (8.6, 95% confidence interval [CI] = 7.9 to 9.4) compared with Tyrer-Cuzick (4.4, 95% CI = 3.9 to 4.9) and NCI BCRAT (3.8, 95% CI = 3.3 to 4.3) models (P &lt; .001). Area under the receiver operating characteristic curves of the deep learning model (0.68, 95% CI = 0.66 to 0.70) was higher compared with Tyrer-Cuzick (0.57, 95% CI = 0.54 to 0.60) and NCI BCRAT (0.57, 95% CI = 0.54 to 0.60) models. Simulated screening of the top 50th percentile risk by the deep learning model captured statistically significantly more patients with cancer compared with Tyrer-Cuzick and NCI BCRAT models (P &lt; .001). A deep learning model to assess breast cancer risk can support feasible and effective risk-based screening and is superior to traditional models to identify patients destined to develop cancer in large screening cohorts.

Sentiment analysis is a subfield of Natural Language Processing (NLP) which tries to process a text to extract opinions or attitudes towards topics or entities. Recently, the use of deep learning methods for sentiment analysis has received noticeable attention from researchers. Generally, different deep learning methods have shown superb performance in sentiment analysis problem. However, deep learning models are different in nature and have different strengths and limitations. For example, convolutional neural networks are useful for extracting local structures from data, while recurrent models are able to learn order dependence in sequential data. In order to combine the advantages of different deep models, in this paper we have proposed a novel approach for aspect-based sentiment analysis which utilizes deep ensemble learning. In the proposed method, we first build four deep learning models, namely CNN, LSTM, BiLSTM and GRU. Then the outputs of these models are combined using stacking ensemble approach where we have used logistic regression as meta-learner. The results of applying the proposed method on the real datasets show that our method has increased the accuracy of aspect-based prediction by 5% to 20% compared to the basic deep learning methods.

Deep learning algorithms can be used to design systems that report data on patients and deliver warnings to medical applications or electronic health information if there are changes in the patient's health. These systems could be created using deep Learning. This helps verify that patients get the proper effective care at the proper time for each specific patient. A healthcare decision support system was presented using the Internet of Things and deep learning methods. In the proposed system, we examined the capability of integrating deep learning technology into automatic diagnosis and IoT capabilities for faster message exchange over the Internet. We have selected the suitable Neural Network structure (number of best-hidden layers and activation function classes) to construct the e-health system. In addition, the e-health system relied on data from doctors to understand the Neural Network. In the validation method, the total evaluation of the proposed healthcare system for diagnostics provides dependability under various patient conditions. Based on evaluation and simulation findings, a dual hidden layer of feed-forward NN and its neurons store the tanh function more effectively than other NN. To overcome challenges, this study will integrate artificial intelligence with IoT. This study aims to determine the NN's optimal layer counts and activation function variations.

The past few years have seen a surge of applying Deep Learning (DL) models for a wide array of tasks such as image classification, object detection, machine translation, etc. While DL models provide an opportunity to solve otherwise intractable tasks, their adoption relies on them being optimized to meet latency and resource requirements. Benchmarking is a key step in this process but has been hampered in part due to the lack of representative and up-to-date benchmarking suites. This is exacerbated by the fast-evolving pace of DL models. This paper proposes DLBricks, a composable benchmark generation design that reduces the effort of developing, maintaining, and running DL benchmarks on CPUs. DLBricks decomposes DL models into a set of unique runnable networks and constructs the original model's performance using the performance of the generated benchmarks. DLBricks leverages two key observations: DL layers are the performance building blocks of DL models and layers are extensively repeated within and across DL models. Since benchmarks are generated automatically and the benchmarking time is minimized, DLBricks can keep up-to-date with the latest proposed models, relieving the pressure of selecting representative DL models. Moreover, DLBricks allows users to represent proprietary models within benchmark suites. We evaluate DLBricks using $50$ MXNet models spanning $5$ DL tasks on $4$ representative CPU systems. We show that DLBricks provides an accurate performance estimate for the DL models and reduces the benchmarking time across systems (e.g. within $95\%$ accuracy and up to $4.4\times$ benchmarking time speedup on Amazon EC2 c5.xlarge).

Artificial intelligence (AI)-based approaches are crucial in computer-aided diagnosis (CAD) for various medical applications. Their ability to quickly and accurately learn from complex data is remarkable. Deep learning (DL) models have shown promising results in accurately classifying Alzheimer's disease (AD) and its related cognitive states, Early Mild Cognitive Impairment (EMCI) and Late Mild Cognitive Impairment (LMCI), along with the healthy conditions known as Cognitively Normal (CN). This offers valuable insights into disease progression and diagnosis. However, certain traditional machine learning (ML) classifiers perform equally well or even better than DL models, requiring less training data. This is particularly valuable in CAD in situations with limited labeled datasets. In this paper, we propose an ensemble classifier based on ML models for magnetic resonance imaging (MRI) data, which achieved an impressive accuracy of 96.52%. This represents a 3-5% improvement over the best individual classifier. We evaluated popular ML classifiers for AD classification under both data-scarce and data-rich conditions using the Alzheimer's Disease Neuroimaging Initiative and Open Access Series of Imaging Studies datasets. By comparing the results to state-of-the-art CNN-centric DL algorithms, we gain insights into the strengths and weaknesses of each approach. This work will help users to select the most suitable algorithm for AD classification based on data availability.

Moving target defenses (MTDs) are widely used as an active defense strategy for thwarting cyberattacks on cyber-physical systems by increasing diversity of software and network paths. Recently, machine Learning (ML) and deep Learning (DL) models have been demonstrated to defeat some of the cyber defenses by learning attack detection patterns and defense strategies. It raises concerns about the susceptibility of MTD to ML and DL methods. Here, in this article, we analyze the effectiveness of ML and DL models when it comes to deciphering MTD methods and ultimately evade MTD-based protections in real-time systems. Specifically, we consider a MTD algorithm that periodically randomizes address assignments within the MIL-STD-1553 protocol—a military standard serial data bus. Two ML and DL-based tasks are performed on MIL-STD-1553 protocol to measure the effectiveness of the learning models in deciphering the MTD algorithm: 1) determining whether there is an address assignments change i.e., whether the given system employs a MTD protocol and if it does 2) predicting the future address assignments. The supervised learning models (random forest and k-nearest neighbors) effectively detected the address assignment changes and classified whether the given system is equipped with a specified MTD protocol. On the other hand, the unsupervised learning model (K-means) was significantly less effective. The DL model (long short-term memory) was able to predict the future addresses with varied effectiveness based on MTD algorithm's settings.

To develop and evaluate static ultrasound images of ovaries-based radiomics and deep learning models for predicting antral follicle count (AFC) and anti-Müllerian hormone (AMH). A retrospective analysis was performed on 395 infertility patients who completed AFC through transvaginal ultrasonography and AMH test in two branches of the hospital. The data set was divided into training cohort (n = 210, Branch A), internal test cohort (n = 91, Branch A), and external test cohort (n = 94, Branch B). The AFC results of static ultrasound images (AFCstatic) and dynamic scan (AFCdynamic) were analysed for correlation and consistency. The radiomics, deep learning and combined models (Rad-DL model) were developed to quantitatively predict AFC and AMH respectively, and the ordered 3-class classification (AFCdynamic≤5,6≤AFCdynamic≤19 and 20≤AFCdynamic) prediction was further carried out. There was a high degree of correlation and consistency between AFCstatic and AFCdynamic in both branches. In the quantitative prediction of AFCdynamic, the R2 of the radiomics, deep learning and Rad-DL models in the external test cohort were 0.572, 0.541, 0.583, respectively. In the quantitative prediction of AMH, the R2 of the radiomics, deep learning and Rad-DL models in the external test cohort were 0.420, 0.352, 0.509, respectively. For the ordered 3-class classification prediction, the radiomics, deep learning and Rad-DL models demonstrated a good discrimination performance with overall AUCs of 0.816 (95%CI, 0.747–0.887), 0.843 (95%CI, 0.772–0.901), and 0.881 (95%CI, 0.816–0.931) in the external test cohort, respectively. Radiomics and deep learning models developed by using static ultrasound images of ovaries may quantitatively predict AFCdynamic to a certain extent, and accurately screen infertility patients with different ovarian reserve levels. This study lays the foundation for further break through the rigid antral follicle count and explore an intelligent non-invasive ovarian reserve evaluation method.

Deep learning-based land cover and land use (LCLU) classification systems are a significant aspiration for remote sensing communities. In nature, remote sensing images have various properties that need to be analyzed. Analyzing and interpreting image properties is difficult due to the nature of the image, the sensor technology’s capability, and other determinant variables such as seasons and weather conditions. The problem is essential for environmental monitoring, agricultural decision-making, and urban planning if it can be supported by deep learning systems. Therefore, deep learning approaches are proposed to quickly analyze and interpret the remote sensing image to classify the LCLU. The deep learning methods could be designed starting from scratch or using pre-trained networks. However, there are few comparisons of deep learning methods developed from scratch and trained on pre-trained networks. Thus, we proposed evaluating and comparing the deep learning models convolutional neural network feature extractor (CNN-FE) by developing it from scratch, transfer learning, and fine-tuning it for the LCLU classification system using remote sensed images. Using CNN-FE, TL, and fine-tuning deep learning models as examples, this paper compares and analyzes deep learning algorithms for remote sensed image classification. After developing and training each deep learning model on the UCM dataset, we evaluated and compared their performances using the performance measurement metrics accuracy, precision, recall, f1-score, and confusion matrix. The proposed deep learning algorithms can adapt and learn the features of the remote sensing images, and the TL and fine-tuning classification performances are significantly improved. As a result of the efficient time used for training the models, this paper discovered that the fine-tuned deep learning model achieved profound accuracy performance results in the UCM dataset.

BACKGROUND Intracranial germ cell tumors (iGCTs) are divided into germinomas (GEs) and nongerminomatous germ cell tumors (NGGCTs), each having distinct treatments and prognoses. However, predictive biomarkers for differentiation are limited. Here, we aim to develop a deep learning (DL) model that can automatically differentiate GEs from NGGCTs using preoperative magnetic resonance (MR) images and analyzing how our model improved clinical decision making among five physicians. METHODS: This multicenter study included patients with pathology-confirmed iGCTs for the developed set (total n = 280), which was split into training (n = 200) and testing datasets (n= 80), and three independent validation datasets (n = 64), respectively. We developed a DL model based on 3D nnU-Net and preoperative MR images to differentiate GEs from NGGCTs. To evaluate the clinical value of the DL model, five physicians' accuracy and level of consistency in identifying tumor types were compared in the testing and three validation datasets, with and without referring to the DL model’s output. RESULTS The DL model achieved AUCs of 0.950, 0.921, 0.869, and 0.905 in the testing and three validation datasets, respectively, which is superior to using conventional information including MR features and clinical information (AUC=0.768, P=0.009). The physicians’ diagnostic performance improved from an average AUC of 0.695 without reference to the DL output to 0.842 using the DL output in the testing and independent validation datasets (21.2% improvement, P=0.014). CONCLUSIONS We developed and validated a DL model using a large dataset to accurately differentiate GEs from NGGCTs using preoperative MR images.

Background Artificial intelligence (AI) has revolutionized diagnostic radiology by improving accuracy, efficiency, and clinical decision-making. While numerous systematic reviews and meta-analyses have evaluated the performance of AI-based techniques, particularly traditional machine learning (ML) and deep learning (DL) models, a comprehensive synthesis of this evidence is lacking. An umbrella review is necessary to integrate and compare findings across various imaging applications, offering the highest level of evidence to inform clinical practice and policy. Objective This umbrella review aims to compare the diagnostic performance of traditional machine learning and deep learning methods in radiology by synthesizing evidence from existing systematic reviews and meta-analyses. Methods A systematic literature search was conducted in PubMed, Scopus, Web of Science, and Cochrane Library for systematic reviews and meta-analyses published between 2018 and 2024. Only peer-reviewed reviews evaluating diagnostic applications of AI in radiology were included. Methodological quality was assessed using the AMSTAR 2 tool, and risk of bias was evaluated using ROBIS. Results Seven systematic reviews and meta-analyses were included. Across multiple imaging domains—such as breast cancer screening, spinal stenosis, and tumor grading—deep learning consistently outperformed traditional ML in diagnostic accuracy and sensitivity. Evidence quality was rated moderate to high, though variability in reporting and a lack of external validation were noted. Explainability features in DL models were underutilized and poorly evaluated. Conclusion This umbrella review confirms the superior diagnostic performance of deep learning methods over traditional ML in radiology. Future research should prioritize model transparency, real-world validation, and standardization in clinical implementation.