Tumor Region Localization in H&E Breast Carcinoma Images Using Deep Convolutional Neural Network

Text recognition in natural scene images is a challenging problem in computer vision. Different than the optical character recognition (OCR), text recognition in natural scene images is more complex due to variations in text size, colors, fonts, orientations, complex backgrounds, occlusion, illuminations and uneven lighting conditions. In this paper, we propose a segmentation-free method based on a deep convolutional recurrent neural network to solve the problem of cursive text recognition, particularly focusing on Urdu text in natural scenes. Compared to the non-cursive scripts, Urdu text recognition is more complex due to variations in the writing styles, several shapes of the same character, connected text, ligature overlapping, stretched, diagonal and condensed text. The proposed model gets a whole word image as an input without pre-segmenting into individual characters, and then transforms into the sequence of the relevant features. Our model is based on three components: a deep convolutional neural network (CNN) with shortcut connections to extract and encode the features, a recurrent neural network (RNN) to decode the convolutional features, and a connectionist temporal classification (CTC) to map the predicted sequences into the target labels. To increase the text recognition accuracy further, we explore deeper CNN architectures like VGG-16, VGG-19, ResNet-18 and ResNet-34 to extract more appropriate Urdu text features, and compare the recognition results. To conduct the experiments, a new large-scale benchmark dataset of cropped Urdu word images in natural scenes is developed. The experimental results show that the proposed deep CRNN network with shortcut connections outperform than other network architectures. The dataset is publicly available and can be downloaded from <uri xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">https://data.mendeley.com/datasets/k5fz57zd9z/1</uri> .

Seeing through disguise: Getting to know you with a deep convolutional neural network

Maize kernel traits such as kernel length, kernel width, and kernel number determine the total kernel weight and, consequently, maize yield. Therefore, the measurement of kernel traits is important for maize breeding and the evaluation of maize yield. There are a few methods that allow the extraction of ear and kernel features through image processing. We evaluated the potential of deep convolutional neural networks and binary machine learning (ML) algorithms (logistic regression (LR), support vector machine (SVM), AdaBoost (ADB), Classification tree (CART), and the K-Neighbor (kNN)) for accurate maize kernel abortion detection and classification. The algorithms were trained using 75% of 66 total images, and the remaining 25% was used for testing their performance. Confusion matrix, classification accuracy, and precision were the major metrics in evaluating the performance of the algorithms. The SVM and LR algorithms were highly accurate and precise (100%) under all the abortion statuses, while the remaining algorithms had a performance greater than 95%. Deep convolutional neural networks were further evaluated using different activation and optimization techniques. The best performance (100% accuracy) was reached using the rectifier linear unit (ReLu) activation procedure and the Adam optimization technique. Maize ear with abortion were accurately detected by all tested algorithms with minimum training and testing time compared to ear without abortion. The findings suggest that deep convolutional neural networks can be used to detect the maize ear abortion status supplemented with the binary machine learning algorithms in maize breading programs. By using a convolution neural network (CNN) method, more data (big data) can be collected and processed for hundreds of maize ears, accelerating the phenotyping process.

1 - Congruence of deep learning in biomedical engineering: future prospects and challenges

Self-mixing interferometry (SMI) is superior to other laser interferometry methods due to its simplicity and compactness. However, SMI signals are often complex and difficult to process due to interference in the form of variations in the effective reflectivity of the target, noisy signals, complex signal shapes, and other dependencies. Deep neural networks have been a very popular area of research in computer artificial intelligence in recent years, allowing more implicit features to be uncovered than traditional shallow machine learning. It has been shown that convolutional and back-propagation neural networks can be used for SMI signal processing. There are also studies that have used machine learning genetic algorithms for absolute distance measurement. Based on the above, this study used convolutional neural networks to form a deep neural network for absolute distance measurement based on SMI technology. We first trained the deep convolutional neural network at different feedback strengths. The results of the Convolutional Neural Network (CNN) model showed a coefficient of determination of 0.9987. which is consistent with the required model. The trained network was then used to estimate absolute distances with and without the addition of noise. The comparison proves that the proposed method is noise-proof and has high adaptability for measurements under different conditions.

Purpose: The aim of the article is to develop an algorithm for classifying cracks in the analyzed images using modern methods of deep machine learning and transfer learning based on pretrained convolutional neural network - Inception-ResNet-v2. Design/Methodology/Approach: Transfer learning based on the pretrained convolutional neural network was used to categorize the images. The fully conected layer of the Inception-ResNet-v2 network has been modified. The last layer was trained using a two-class (binary) linear SVM (Support Vector Machine). In total, 20,000 training cases (images) were used to train the fully connected layer within transfer learning process. The research analyzed the possibility of using the deep neural networks for quick and fully automatic identification of cracks / defects on the surface of analyzed parts. Findings: The results indicate that pretrained convolutional neural network using SVM to train a fully connected layer is a very effective solution for visual crack / fault detection. In the analyzed model, a positive classification was obtained at the level of 99.89%. Practical Implications: The model presented in the article can be used in quality control carried out by process monitoring. An effective model for identifying defective parts can be used in both logistics and production processes. Originality/Value: A novelty is the use of a freely available, deep neural network trained to classify 1000 categories of various images for binary categorization of faults (cracks). The algorithm was adjusted by replacing the primary, 1000-output fully connected layer in the Inception-ResNet-v2 network with a binary layer (2 categories). The fully connected layer has been trained using the classification version of the popular SVM learner, but thanks to the combination of this layer with the sophisticated fearure extraction ability of the pre-trained Inception-ResNet-v2 deep network, the resulting predictive model enables the classification of defects with a very high level of accuracy.

Deep learning (also known as deep structured learning, hierarchical learning, or deep machine learning) is a branch of machine learning based on a set of algorithms that attempt to model high-level abstractions in data by using a deep graph with multiple processing layers, composed of multiple linear and nonlinear transformations. Deep learning has been characterized as a class of machine learning algorithms with the following characteristics [257]: • They use a cascade of many layers of nonlinear processing units for feature extraction and transformation. Each successive layer uses the output from the previous layer as input. The algorithms may be supervised or unsupervised and applications include pattern analysis (unsupervised) and classification (supervised). • They are based on the (unsupervised) learning of multiple levels of features or representations of the data. Higher-level features are derived from lower-level features to form a hierarchical representation. • They are part of the broader machine learning field of learning representations of data. • They learn multiple levels of representations that correspond to different levels of abstraction; the levels form a hierarchy of concepts. These definitions have in common: multiple layers of nonlinear processing units and the supervised or unsupervised learning of feature representations in each layer, with the layers forming a hierarchy from low-level to high-level features. Various deep learning architectures such as deep neural networks, convolutional deep neural networks, deep belief networks (DBN), and recurrent neural networks have been applied to fields like computer vision, automatic speech recognition, natural language processing, audio recognition, and bioinformatics where they have been shown to produce state-of-the-art results on various tasks. In this chapter we start in Section 7.1 with an introduction, giving a brief history of this field, the relevant literature, and its applications. Then we study some basic concepts of deep learning such as convolutional neural networks, recurrent neural networks, backpropagation algorithm, restricted Boltzmann machines, and deep learning networks in Section 7.2. Then we illustrate three examples for Apache Spark implementation for mobile big data (MBD), user moving pattern extraction, and combination with nonparametric Bayesian learning, respectively, in Sections 7.3 through 7.5. Finally, we have summary in Section 7.6.

Deep convolutional neural networks (CNNs) enable learning trainable, highly representative and hierarchical image feature from sufficient training data which makes rapid progress in computer vision possible. There are currently three major techniques that successfully employ CNNs to medical image classification: training the CNN from scratch, using off-the-shelf pretrained CNN features, and transfer learning , i.e., fine-tuning CNN models pretrained from natural image dataset (such as large-scale annotated natural image database: ImageNet) to medical image tasks. In this chapter, we exploit three important factors of employing deep convolutional neural networks to computer-aided detection problems. First, we exploit and evaluate several different CNN architectures including from shallower to deeper CNNs: classical CifarNet, to recent AlexNet and state-of-the-art GoogLeNet and their variants. The studied models contain five thousand to 160 million parameters and vary in the numbers of layers. Second, we explore the influence of dataset scales and spatial image context configurations on medical image classification performance. Third, when and why transfer learning from the pretrained ImageNet CNN models (via fine-tuning) can be useful for medical imaging tasks are carefully examined. We study two specific computer-aided detection (CADe) problems, namely thoracoabdominal lymph node (LN) detection and interstitial lung disease (ILD) classification. We achieve the state-of-the-art performance on the mediastinal LN detection and report the first fivefold cross-validation classification results on predicting axial CT slices with ILD categories. Our extensive quantitative evaluation, CNN model analysis, and empirical insights can be helpful to the design of high-performance CAD systems for other medical imaging tasks, without loss of generality.

Introduction: Water exchange (WE) improves polyp (PDR) and adenoma detection rate (ADR) compared with air insufflation [GIE 2021;93:1411], but still misses polyps due to human limitations [JCG 2021, in press]. A computer-aided detection (CADe) algorithm can overcome human omissions, but is limited by false positives (FPs) [Lancet Gastroenterol & Hepatol 2019;4:71], which might be reduced by salvage-cleaning effect provided by insertion WE [Tzu-Chi Med J 2021;33:108]. We hypothesized that the strengths of CADe and WE can complement the weaknesses of each other. Their combination can enhance PDR and ADR and reduce false positive rate (FPR). Methods: We used a locally developed convolutional neural network with YOLOv4 to build a CADe model. Images of polyps (n=15961) were divided in 80% and 20% for training and testing. Prior to real-time application, we validated the model in detecting polyps, using edited and coded withdrawal phase videos of the right colon from a RCT comparing right colon adenoma detection between WE and air insufflation. The polyps detected by the CADe were confirmed by the consensus of 2 blinded reviewers (experienced endoscopists). We also developed a computer-aided diagnosis (CADx) model based on YOLOv4 to characterize the detected polyps as adenomas or not. The primary and secondary outcomes were PDR and the FPR, respectively. Results: A total of 245 coded videos of colonoscopies inserted with WE (n=123) or air insufflation (n=122) were analyzed. CADe achieved significantly higher PDR in the WE group (61.8%) than in the air insufflation group (40.2%), P=0.0009. CADe also had significantly higher additional PDR in the WE group (30.1% vs 12.3%, P=0.001). The CADx assessed ADR was significantly higher in the WE group than that in the air insufflation group (46.3% vs 30.3%, P=0.018), after the detected polyps were characterized by the CADx. (Table a) The mean numbers of FPs related to feces [1.78 (1.67) vs 2.09 (2.09), P=0.007] and bubbles [0.53 (0.89) vs 1.25 (2.45), P=0.001] were significantly lower in the WE group than in the air insufflation group. (Table b). Conclusion: The data confirmed the hypothesis that the strengths of CADe and WE complemented the weaknesses of each other, enhanced PDR and ADR and reduced FPR. The locally developed CADe and CADx are validated for polyp detection and adenoma assignment for real-time application. Furthermore, WE provides an optimal platform for the computer-assisted algorithms.Table 1.: ADR, adenoma detection rate; All the percentages calculated according to respective total number of patients for each group; PDR, polyp detection rate; Total numbers of polyps were based on those found by the performing endoscopist plus those detected by the CADe; Proportion of additional polyps found by CADe equals numbers of additional polyp (adenomas) found by CADe divided by total numbers of polyps (adenomas). Others: ileocecal valve, cecum, polypectomy site, suction marks and drug pills. † Mann-Whitney test; ††Fisher exact test.

Predictive analysis on cellular traffic is important for the control and monitoring of wireless networks. Cellular traffic prediction is a challenging problem due to the non- stationarity and dynamic spatial-temporal correlation of the traffic. In this paper, we address the problem of accurate traffic prediction in a base station by proposing a deep neural network called RAConv. Its structure includes residual network, attention mechanism, and deep convolutional network. In the proposed architecture, a deep 3D residual convolutional network (ResConv3D) with three residual blocks are employed to learn the local spatial-temporal features. An attention-aided convolutional long short-term memory network (AConvLSTM) is then used to capture the long-term spatial-temporal dependencies. The use of the attention modules enable the network to focus on the most important spatial-temporal information. We evaluate the performance of the proposed RAConv network using a dataset provided by a Canadian wireless service provider. We consider the traffic prediction on two time scales (i.e., hourly and daily), which exhibit different spatial-temporal dependency patterns. Experimental results show that the proposed RAConv network can achieve accurate prediction under both time scales. Results also show that our proposed network provides a lower root-mean-square error (RMSE) than the conventional ConvLSTM baseline scheme.

Handwritten digit recognition is the intelligence of computers to recognize digits written by humans. But it becomes one of the most challenging tasks for machines as handwritten digits are not perfect and can be made with many different: flavors, size, thickness. Thus, as a solution to this problem, Handwriting digit recognition model comes into picture. Many machine learning techniques have been employed to solve the handwritten digit recognition problem. This paper focuses on Neural Network (NN) approaches. Among the three famous NN approaches: deep neural network (DNN), deep belief network (DBN) and convolutional neural network (CNN), the specialization of CNN as compared to other NN of being able to detect pattern is what makes it so useful for recognizing handwritten digits. Humans can very easily see, read &amp; write any handwritten digits, when written in proper format. Even if the digits are not written in proper format we can use our logic and predict what digit it could be. But It is a hard task for the machine to recognize handwritten digits as these are not perfect and can be made with many different flavors. Thus handwritten digit recognition is the solution to this problem which uses the image of a digit and recognizes the digit present in the image. The handwritten digit recognition is the ability of computers to recognize human handwritten digits. The goal is to build a model that can efficiently and reliably recognize the digits and output the proper result. Amongst all the other neural networks, working and implementing a model using Convolution Neural Network gives out the most precise results. It is most popularly used for analyzing images as well as for other data analysis or classification problems. CNN has hidden layers called convolutional layers. These layers work the same way as other layers do but here we need to specify the no of filters each layer should have These filters are actually what detects the pattern. Patterns could be edges, corners, circles or any complex other objects like eyes, ears or even deeper full dogs, cats, etc. Thus, the specialization of CNN as compared to other NN of being able to detect patterns is what makes it so useful for recognizing handwritten digits Key Word: Neural Networks; Convolutional Neural Networks (CNN); Image Processing; Optical Character Recognition (OCR); MNIST Dataset

An end-to-end deep convolutional neural network (CNN) based on deep residual network (ResNet) was proposed to efficiently reconstruct reliable T2 mapping from single-shot overlapping-echo detachment (OLED) planar imaging. The training dataset was obtained from simulations that were carried out on SPROM (Simulation with PRoduct Operator Matrix) software developed by our group. The relationship between the original OLED image containing two echo signals and the corresponding T2 mapping was learned by ResNet training. After the ResNet was trained, it was applied to reconstruct the T2 mapping from simulation and in vivo human brain data. Although the ResNet was trained entirely on simulated data, the trained network was generalized well to real human brain data. The results from simulation and in vivo human brain experiments show that the proposed method significantly outperforms the echo-detachment-based method. Reliable T2 mapping with higher accuracy is achieved within 30 ms after the network has been trained, while the echo-detachment-based OLED reconstruction method took approximately 2 min. The proposed method will facilitate real-time dynamic and quantitative MR imaging via OLED sequence, and deep convolutional neural network has the potential to reconstruct maps from complex MRI sequences efficiently.

Accurate segmentation of the retinal microvasculature is a critical step in the quantitative analysis of the retinal circulation, which can be an important marker in evaluating the severity of retinal diseases. As manual segmentation remains the gold standard for segmentation of optical coherence tomography angiography (OCT-A) images, we present a method for automating the segmentation of OCT-A images using deep neural networks (DNNs). Eighty OCT-A images of the foveal region in 12 eyes from 6 healthy volunteers were acquired using a prototype OCT-A system and subsequently manually segmented. The automated segmentation of the blood vessels in the OCT-A images was then performed by classifying each pixel into vessel or nonvessel class using deep convolutional neural networks. When the automated results were compared against the manual segmentation results, a maximum mean accuracy of 0.83 was obtained. When the automated results were compared with inter and intrarater accuracies, the automated results were shown to be comparable to the human raters suggesting that segmentation using DNNs is comparable to a second manual rater. As manually segmenting the retinal microvasculature is a tedious task, having a reliable automated output such as automated segmentation by DNNs, is an important step in creating an automated output.

Evaluation of the benchmark datasets for testing the efficacy of deep convolutional neural networks

Identification of crops is an important topic in the agricultural domain. Hyperspectral remote sensing data are very useful for crop feature extraction and classification. Remote sensing data is an unstructured data and Convolutional Neural Network (CNN) can work on unstructured data efficiently. This paper presents an evaluation of CNN for crop classification using the Indian Pines standard dataset obtained from the AVIRIS sensor and the study area dataset obtained from the EO-1hyperion sensor. Optimized CNN has been tuned by training the model on different parameters. It has been compared with two classification algorithms: Deep Neural Network (DNN) and Convolutional Autoencoder. According to the test results, the proposed optimized CNN model provided better results as compared to the other two methods. CNN has given 97 ± 0.58% overall accuracy for the Indian Pines standard dataset and 78 ± 2.43% for our study area dataset.