VIRTUOUS CIRCLES

Previous articleNext article No AccessPractical Reason and the Possibility of Error*Douglas LavinDouglas Lavin Search for more articles by this author PDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinkedInRedditEmail SectionsMoreDetailsFiguresReferencesCited by Ethics Volume 114, Number 3April 2004 Article DOIhttps://doi.org/10.1086/381695 Views: 241Total views on this site Citations: 42Citations are reported from Crossref © 2004 by The University of Chicago. All rights reserved.PDF download Crossref reports the following articles citing this article:Roy Sorensen Commandments Thou Shalt Not Break, Philosophia 34 (Dec 2022).https://doi.org/10.1007/s11406-022-00602-zWinnie Sung Ratiocination, Asian Journal of Philosophy 1, no.22 (Oct 2022).https://doi.org/10.1007/s44204-022-00049-9Robert Shaver Moral error theory and hypothetical reasons, Synthese 200, no.44 (Jun 2022).https://doi.org/10.1007/s11229-022-03759-yCarla Bagnoli Ethical Constructivism, 16 (Jan 2022).https://doi.org/10.1017/9781108588188Jeremy David Fix Two Sorts of Constitutivism, Analytic Philosophy 62, no.11 (Oct 2019): 1–20.https://doi.org/10.1111/phib.12166Janis David Schaab On the Supposed Incoherence of Obligations to Oneself, Australasian Journal of Philosophy 99, no.11 (Feb 2020): 175–189.https://doi.org/10.1080/00048402.2020.1714677SHEILA WEBB Chapter 2 Dualisms, Distinctions and Unity, Journal of Philosophy of Education 54, no.66 (Dec 2020): 1522–1533.https://doi.org/10.1111/1467-9752.12533David N. McNeill The virtue of error: Solved games and ethical deliberation, European Journal of Philosophy 28, no.33 (Oct 2020): 639–656.https://doi.org/10.1111/ejop.12595Samuel Gavin Constitutivism and Generics, Philosophia 48, no.33 (Sep 2019): 1015–1036.https://doi.org/10.1007/s11406-019-00120-5Luca Ferrero Constitutivism, Moral, (Jun 2020): 1–12.https://doi.org/10.1002/9781444367072.wbiee877Jeremy David Fix The Error Condition, Canadian Journal of Philosophy 50, no.11 (Oct 2019): 34–48.https://doi.org/10.1017/can.2019.14Arash Abizadeh Subjectivism, instrumentalism, and prudentialism about reasons: On the normativity of instrumental transmission, European Journal of Philosophy 27, no.22 (Sep 2018): 387–402.https://doi.org/10.1111/ejop.12402Sergio Tenenbaum Formalism and constitutivism in Kantian practical philosophy, Philosophical Explorations 22, no.22 (May 2019): 163–176.https://doi.org/10.1080/13869795.2019.1599053Charles Côté-Bouchard ‘Ought’ implies ‘can’ against epistemic deontologism: beyond doxastic involuntarism, Synthese 196, no.44 (Aug 2017): 1641–1656.https://doi.org/10.1007/s11229-017-1531-8Fabienne Peter III—Normative Facts and Reasons, Proceedings of the Aristotelian Society 119, no.11 (Apr 2019): 53–75.https://doi.org/10.1093/arisoc/aoz002David Enoch Constitutivism: On Rabbits, Hats, and Holy Grails, SSRN Electronic Journal 127 (Jan 2019).https://doi.org/10.2139/ssrn.3382239PETER BRIAN ROSE-BARRY Defective Actions and Tyrannical Souls: Korsgaard on Evil, Dialogue 57, no.11 (Sep 2017): 29–46.https://doi.org/10.1017/S0012217317000567Herlinde Pauer-Studer Korsgaard’s Constitutivism and the Possibility of Bad Action, Ethical Theory and Moral Practice 21, no.11 (Nov 2017): 37–56.https://doi.org/10.1007/s10677-017-9851-9Fabienne Peter The Good, the Bad, and the Uncertain: Intentional Action under Normative Uncertainty, Ethical Theory and Moral Practice 21, no.11 (Dec 2017): 57–70.https://doi.org/10.1007/s10677-017-9852-8David G. Dick Constitutivism, Error, and Moral Responsibility in Bishop Butler's Ethics, The Southern Journal of Philosophy 55, no.44 (Dec 2017): 415–438.https://doi.org/10.1111/sjp.12262Samuel Asarnow The Reasoning View and Defeasible Practical Reasoning, Philosophy and Phenomenological Research 95, no.33 (Sep 2017): 614–636.https://doi.org/10.1111/phpr.12446 홍우람 Brandom’s Kant: The Normativity of Concepts, Sogang Journal of Philosophy 50, no.nullnull (Aug 2017): 295–322.https://doi.org/10.17325/sgjp.2017.50..295Cristina Borgoni, Yannig Luthra Epistemic akrasia and the fallibility of critical reasoning, Philosophical Studies 174, no.44 (Jul 2016): 877–886.https://doi.org/10.1007/s11098-016-0711-6Christoph Bambauer Christine Korsgaard and the Normativity of Practical Identities, (Apr 2017): 61–85.https://doi.org/10.1007/978-3-319-52398-9_4Michael Kowalik When it is Not Logically Necessary for a Necessary Condition of Value to be Valuable, SSRN Electronic Journal (Jan 2017).https://doi.org/10.2139/ssrn.3737427Adam Cureton Unity of Reasons, Ethical Theory and Moral Practice 19, no.44 (Feb 2016): 877–895.https://doi.org/10.1007/s10677-016-9704-yOlof Leffler The Foundations of Agency – and Ethics?, Philosophia 44, no.22 (Apr 2016): 547–563.https://doi.org/10.1007/s11406-016-9702-2Luca Ferrero Agency, Scarcity, and Mortality, The Journal of Ethics 19, no.3-43-4 (Nov 2015): 349–378.https://doi.org/10.1007/s10892-015-9207-4Laura Papish Kant on the Independence of the Moral Law from Sensibility, Kantian Review 20, no.11 (Jan 2015): 77–98.https://doi.org/10.1017/S1369415414000296Ben Laurence Juridical laws as moral laws in Kant's The Doctrine of Right, (Jan 2015): 205–227.https://doi.org/10.1017/CBO9781107707573.013Markus Kohl Kant on Determinism and the Categorical Imperative, Ethics 125, no.22 (Jun 2015): 331–356.https://doi.org/10.1086/678370Brian O'Connor Play, Idleness and the Problem of Necessity in Schiller and Marcuse, British Journal for the History of Philosophy 22, no.66 (Sep 2014): 1095–1117.https://doi.org/10.1080/09608788.2014.954521Jun Chen, Xiao-feng Ju Establishing a measurement framework indicating regional technology innovation ability, (Aug 2014): 1570–1575.https://doi.org/10.1109/ICMSE.2014.6930420 Bibliography, (Apr 2014): 249–256.https://doi.org/10.14220/9783737002271.249 Bibliography, (Aug 2013): 295–302.https://doi.org/10.1002/9781118609088.biblioJonathan Way Explaining the Instrumental Principle, Australasian Journal of Philosophy 90, no.33 (Sep 2012): 487–506.https://doi.org/10.1080/00048402.2011.598174David Alm, Defending Fundamental Requirements of Practical Reason, Journal of Philosophical Research 36 (Jan 2011): 77–102.https://doi.org/10.5840/jpr_2011_8Arthur Ripstein Critical Notice, Canadian Journal of Philosophy 40, no.44 (Jan 2020): 669–699.https://doi.org/10.1080/00455091.2010.10716739Jonathan Way Defending the wide-scope approach to instrumental reason, Philosophical Studies 147, no.22 (Oct 2008): 213–233.https://doi.org/10.1007/s11098-008-9277-2David Enoch Can there be a global, interesting, coherent constructivism about practical reason?, Philosophical Explorations 12, no.33 (Sep 2009): 319–339.https://doi.org/10.1080/13869790903067683David Alm Deontological Restrictions and the Self/Other Asymmetry, Noûs 42, no.44 (Nov 2008): 642–672.https://doi.org/10.1111/j.1468-0068.2008.00695.xDavid Enoch Agency, Shmagency: Why Normativity Won't Come from What Is Constitutive of Action, The Philosophical Review 115, no.22 (Apr 2006): 169–198.https://doi.org/10.1215/00318108-2005-014

Focus on Authors

Starting with this issue, the Editorial duties for the JCI move to Duke University and the University of North Carolina at Chapel Hill. As we begin our five-year tenure at the helm of this prestigious journal, the tradition of excellence that these two schools typically display on the basketball court now enters the editorial boardroom.

Journal-related Activities and Other Special Activities at the 2011 American Society of Anesthesiologists Annual Meeting

merican healthcare has been described as a “non-system,” but there have been persistent efforts to coordinate and rationalize how we provide medical care in the United States. These efforts have resulted in what may be called informal systems of care. A perfect example of one of those systems is in North Carolina, a system created for the people of the state’s smaller and poorer communities, communities that are most often rural and more often inhabited by racial and ethnic minority citizens. Almost all of North Carolina could have been called rural at the end of World War II. The 1940 Census classified 72.7% of the state’s population as rural or living in communities with fewer than 2,500 residents. A few cities—Charlotte, Durham, Greensboro, Asheville, Raleigh—had modestly large populations, but no city in the state had a population greater than 110,000. The state’s economy was strongly linked to agriculture, and the prevailing perception of North Carolina was of a sleepy, rural, somewhat backward state. World War II created an economic stimulus for the state when military installations were located in North Carolina— shipyards were established in Wilmington to build liberty ships, and facilities were developed to house prisoners of war in the central and the mountain regions of the state. But the war left another legacy beyond economic benefit: the state had experienced the highest medical rejection rate for its draftees of any state in the Union. The causes for rejection were usually chronic problems related to nutrition and poor or unavailable basic medical care and health advice. This embarrassing fact is often cited as the driver of the statewide “Good Health Campaign” promoted in 1949 by prominent North Carolinians, including Kay Kyser, who recruited radio personalities and Hollywood stars to help raise money and direct attention to the healthcare needs of the state. That public effort had a significant impact, but it built on prior efforts to expand health resources. For years, politicians had been debating whether to assist one or both of the private medical schools in the state (Duke University and Bowman Gray) or whether to create a large medical center by expanding the two-year medical school at the state university in Chapel Hill. Governor Melville Broughton appointed a Medical Care Commission in 1944 to study the health and medical needs of the state. That commission recommended the creation of a new, state-supported, four-year medical school in Chapel Hill that would share space with the existing School of Public Health and occupy space adjacent to a new, comprehensive teaching hospital. After years of consideration, the General Assembly supplied construction funds that were combined with money from the Hospital Planning and Construction Act of 1947, the Hill-Burton Act, to build Memorial Hospital in Chapel Hill and to create the teaching hospital. The Hill-Burton program also supported the construction of many North Carolina hospitals and public health facilities in

Southward, Ho! David Moltke-Hansen Mapping the Archival South In 1901, Alabama created the first state archives in the United States, followed quickly by many other southern states. Despite the vision and commitment behind them, these initial efforts were too meagerly funded to go far toward solving a critical problem of southern studies: the scarcity of accessible original sources, print as well as manuscript. Thirty years later, after the University of North Carolina at Chapel Hill, the University of Virginia, and Duke University had launched what would become three of the largest, sustained programs for collecting the private papers of southerners, this scarcity remained a major stumbling block to research on the South. Today, the problem is very different: source materials are abundant. Although there are still many gaps in the historical record, more than 2,000 repositories across the region have collected at least some documentation on aspects of the archival South. They hold perhaps 1.5 million shelf feet altogether—roughly 300 miles or 3 billion pages of documentation. In addition, they house more than 15 million photographs, more than 1.5 million audio recordings (including perhaps as many as 75,000 oral histories), and tens of thousands of reels and cores of film and videotape. If local government office, business, and organizational holdings and southern Americana in the District of Columbia, northern , and foreign institutions were included, these totals might more than triple. Libraries have also collected hundreds of thousands of fugitive pamphlets and books from and about the region, as well as millions of issues of newspapers and other periodicals. The North Carolina Collection at the University of North Carolina at Chapel Hill alone has nearly 200,000 books and pamphlets and 3,000 serials documenting the Tar Heel state and its citizens. Researchers still have to spend time looking for primary materials, but now they must spend much of their time sorting through the masses of documentation available to them as well. Although the archivists of these materials have been accelerating their automation of catalog records, it will be at least another decade before the majority of southern Americana will be cataloged in the Online Computer Library Center (OCLC), the Research Libraries Information Network (RLIN), or other bibliographic utilities. In these circumstances, researchers more than ever need mechanisms to communicate, analyze, and address methodological problems related to research opportunities in the rapidly growing mountains of documentation about the South and its people. Many rich collections have scarcely been touched, often because they are unprocessed or uncataloged. In some institutions, more than half of the holdings are backlogged and thus more or less inaccessible. In other cases, the problem lies with older 134Southern Cultures research aids, abysmal by current standards. It is simply no longer possible for researchers to examine every archived document from the period and place of their interest. Indeed, students of the post-World War II South are faced with collections of the papers of individual politicians and organizations that bulk to proportions larger than the papers of all the signers of the Declaration of Independence put together. Clearly, we need more detailed help than we did before to identify and make use of those archived materials potentially most relevant to us. "Southward, Ho!" will offer a venue for communicating and analyzing these research opportunities and issues. Here authors will canvass newly available or little-used resources in particular repositories on particular topics, and consider broad methodological issues associated with investigating these topics. They will alert readers to kinds of work underway but not yet published, or report to a wider readership aspects or trends of current work in one specialty or another. From time to time, too, contributors to "Southward , Ho!" will reflect on how to access and assess the primary sources for the study of southern cultures. We hope that you will consider helping us put southern cultural research opportunities and issues in perspective for our readers. Please communicate your suggestions, comments, or offerings to: David Moltke-Hansen, Director Southern Historical and Folklife Collections UNC-CH, Chapel Hill, NC 27599-3926 (919) 962-1345 (telephone) (919) 962-0484 (fax) DavidMH@UNCMVS.OIT.UNC.EDU (e-mail) In the meantime, consider the...

Editorial introductions

HomeRadiologyVol. 302, No. 1 PreviousNext CommunicationsFree AccessSpecial Communications2021 RSNA Outstanding ResearcherMary C. MahoneyMary C. MahoneyMary C. MahoneyPublished Online:Nov 30 2021https://doi.org/10.1148/radiol.219024MoreSectionsPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In Pamela K. Woodard, MDDownload as PowerPointOpen in Image Viewer A leading researcher in cardiothoracic imaging and a generous mentor, Pamela K. Woodard, MD, specializes in cardiac CT and MRI techniques and in translating novel cardiovascular PET radiotracers into human subjects.“Dr Woodard is truly an outstanding researcher,” said RSNA President Mary C. Mahoney, MD. “She is respected not only for her enormous success in funded research, but her generous mentoring of so many of our future leaders in imaging research.”Dr Woodard is the Hugh Monroe Wilson professor of radiology and professor of biomedical engineering at the Mallinckrodt Institute of Radiology, Washington University in St Louis, Mo, where she is also the senior vice chair and division director of Radiology Research Facilities. In this role, she provides administrative oversight to the directors of the department’s 10 National Institutes of Health (NIH) research facilities, including the preclinical and clinical imaging PET and MRI research facilities and the Cyclotron Facility. She is also director of the Center for Clinical Imaging Research, head of Cardiac MR/CT, director of the Radiology Research Resident Track, and the program director of the NIH-funded T32 TOP-TIER (Training Opportunities in Translational Imaging Education and Research) clinician-scientist training program in translational imaging research.Dr Woodard received her undergraduate degree from Duke University in Durham, NC, and her medical degree from the Duke University School of Medicine. She completed her internship in internal medicine at the University of North Carolina at Chapel Hill, a residency in diagnostic radiology at Duke University, and a fellowship in cardiothoracic imaging at the Mallinckrodt Institute of Radiology.Following early success in securing grant funding, including a 1996 Siemens Medical Solutions/RSNA Research Fellow Grant and a 1999 Carestream Health/RSNA Research Scholar Grant, Dr Woodard secured multiple NIH grants. Early in her career, she was a principal investigator (PI) on the landmark NIH-funded PIOPED II project, published in the New England Journal of Medicine, which established multi-detector CT as the principal method for pulmonary embolism diagnosis. She also led a key project on the Washington University NIH contract, Programs of Excellence in Nanotechnology, which developed a receptor-targeted radiotracer for atherosclerotic plaque imaging.Dr Woodard currently leads her own research program and is a PI or MPI on three NIH R01 grants for the translation of cardiovascular radiotracers into humans. She has nearly 200 peer-reviewed manuscripts, several patents, and has served as a charter member on NIH study sections, including Clinical and Integrative Cardiovascular Sciences (CICS) and Medical Imaging (MEDI), and chair of the NIH study section, Imaging Guided Interventions and Surgery. She has received numerous awards for her work, including being named an Academy of Radiology and Biomedical Imaging Research (ARBIR) Distinguished Investigator.A revered leader in organized radiology, Dr Woodard serves on the board of directors of ARBIR and the Missouri Radiological Society. She also serves on the American College of Radiology (ACR) Board of Chancellors as the ACR chair of the Commission on Research. She is a past president of the North American Society for Cardiovascular Imaging. Her expertise has informed the R&E Foundation Research Grant Study Section and the Quantitative Imaging Biomarkers Alliance.Article HistoryPublished online: Nov 30 2021Published in print: Jan 2022 FiguresReferencesRelatedDetailsRecommended Articles Linda Moy, MD, Named New Editor of RadiologyRadioGraphics2022Volume: 42Issue: 2pp. E37-E38Linda Moy, MD, Named New Editor of RadiologyRadiology2022Volume: 303Issue: 1pp. 3-4David A. Bluemke, MD, PhD, Named Editor of RadiologyRadiology2016Volume: 282Issue: 1pp. 10-11David A. Bluemke, MD, PhD, Named Editor of RadiologyRadioGraphics2017Volume: 37Issue: 1pp. 5-62020 RSNA Outstanding ResearcherRadiology2020Volume: 298Issue: 1pp. 1See More RSNA Education Exhibits Imaging of Suspected Pulmonary Embolism and Deep Venous Thrombosis in Obese PatientsDigital Posters2020Clinical Aspects Relating to Acute Pulmonary Embolism ImagingDigital Posters2018Acute Pulmonary Embolism: The Role of the Radiologist from Diagnosis to TreatmentDigital Posters2018 RSNA Case Collection Acute pulmonary embolismRSNA Case Collection2022Carotid WebRSNA Case Collection2020Pulmonary Embolism with Right Heart StrainRSNA Case Collection2020 Vol. 302, No. 1 Metrics Altmetric Score PDF download

Focus on Authors

Born in 1943 in South Carolina, Evans graduated from high school in Dallas, Texas, and received her B.A. and M.A. degrees from Duke University and her Ph.D. from the University of North Carolina, Chapel Hill. She began teaching at the University of Minnesota in 1976 and has been Distinguished McKnight University Professor since 1997. Her Personal Politics related U.S. women's liberation to the Civil Rights and New Left movements. Her Born for Liberty: A History of American Women is in its second edition and has been translated into a number of foreign languages. A noted activist, feminist, and teacher, Evans has coauthored books on women's history, consulted on several video productions, participated in national review panels, and served on the boards of various professional organizations. She has a 31‐year‐old son and a 19‐year‐old adopted daughter from Korea. This interview was conducted in Evans's office at the University of Minnesota by Roger Adelson in March 2000.

Background Current data on infectious complications of chimeric antigen receptor (CAR) T-cell therapy are limited to single center retrospective cohort studies. Presented here is a subset of patients from a multicenter retrospective cohort study including recipients of CAR T-cell therapy at Duke University, University of North Carolina at Chapel Hill, and Stanford University. Methods In a retrospective cohort of 66 patients who received CD19 CAR T-cell therapy Duke University between January 1, 2018 and August 31, 2021 rates and characteristics of bacterial, viral, and fungal infections within the first year after CAR T-cell infusion are described. Demographic, baseline clinical, and outcome variables are compared between patients who developed infection and those who did not. Results Forty-nine total infections occurred in 29 (43.9%) patients within 1 year of CAR T-cell infusion. Patients who developed infection were more likely to have an underlying malignancy other than diffuse large B-cell lymphoma (34% vs 8%, p = 0.031), and to have developed immune effector cell-associated neurotoxicity syndrome (62% vs. 32%, p = 0.016). Viral (23/49, 46.9%) and bacterial (20/49, 40.8%) pathogens predominated and infections most often involved the bloodstream (19/49, 38.8%) and lung (18/49, 36.7%).There were no statistically significant differences between rates of bacterial and viral infection based on time since CAR T-cell infusion (≤30 days vs 30 – 90 days vs >90 days), though fungal infections only occurred after 90 days in patients with relapse of their underlying disease. Conclusion Infectious complications after CAR T-cell therapy are common within the first year of infusion. Bacterial and viral infections predominate while fungal infections are rare and occurred only in patients with relapsed disease. Disclosures Melody Smith, MD, MS, BMS: Advisor/Consultant Krista Rowe-Nichols, RN, MSN, AOCNS, Bristol Myers Squibb: Advisor/Consultant|Kite Pharmaceuticals: Advisor/Consultant|Kite Pharmaceuticals: Speaker Bureau Christopher Kelsey, MD, Colgate-Palmolive: Expert Testimony|Johnson and Johnson: Expert Testimony Taewoong Choi, MD, Janssen biotech: Honoraria Matthew McKinney, MD, ADC Therapeutics: Advisor/Consultant|ADC Therapeutics: Honoraria|Beigene: Grant/Research Support|Beigene: Honoraria|Epizyme: Advisor/Consultant|Genentech: Advisor/Consultant|Genentech: Grant/Research Support|Genentech: Honoraria|Gilead/Kite: Advisor/Consultant|Gilead/Kite: Honoraria|Incyte: Grant/Research Support|Novartis: Advisor/Consultant|Seagen, Inc.: Advisor/Consultant|Takeda: Advisor/Consultant|TG therapeutics: Advisor/Consultant

International Mendelssohn-Schumann Conference University of North Carolina, Chapel Hill and Duke University 1-3 April, 1982

Sönke Johnsen is a Professor at Duke University, USA, investigating visual ecology. After completing his degree in mathematics at Swarthmore College, USA, and a PhD with William Kier at University of North Carolina at Chapel Hill, USA, Johnsen worked as a post-doc with Edie Widder at Harbor Branch Oceanographic Institution, USA, and Larry Madin at Woods Hole Oceanographic Institution, USA. He remained at Woods Hole as an Assistant Scientist before moving to Duke as an Assistant Professor. Johnsen talks about his experiences of collecting transparent animals while blue water diving and in a submersible, as well as outrunning Hurricane Katrina in 2005.

Book Review| January 01 1968 Ballots and Fence Rails: Reconstruction on the Lower Cape Fear by W. McKee Evans Ballots and Fence Rails: Reconstruction on the Lower Cape Fear. By Evans, W. McKee. Chapel Hill: University of North Carolina Press, 1967. Pp. x, 314. $7.50. Robert F. Durden Robert F. Durden Duke University Search for other works by this author on: This Site Google South Atlantic Quarterly (1968) 67 (1): 191. https://doi.org/10.1215/00382876-67-1-191 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Robert F. Durden; Ballots and Fence Rails: Reconstruction on the Lower Cape Fear by W. McKee Evans. South Atlantic Quarterly 1 January 1968; 67 (1): 191. doi: https://doi.org/10.1215/00382876-67-1-191 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsSouth Atlantic Quarterly Search Advanced Search The text of this article is only available as a PDF. Copyright © 1968 by Duke University Press1968 Article PDF first page preview Close Modal You do not currently have access to this content.

In 1998 a collaboration between Duke University and the University of North Carolina, Chapel Hill (UNC) was founded to enhance identification of persons with acute HIV-1 infection (AHI). The Duke-UNC AHI Research Consortium Cohort consists of patients ≥18 years old with a positive nucleic acid amplification test (NAAT) and either a negative enzyme immunoassay (EIA) test or a positive EIA with a negative/indeterminate Western blot. Patients were referred to the cohort from acute care settings and state-funded HIV testing sites that use NAAT testing on pooled HIV-1 antibody-negative samples. Between 1998 and 2010, 155 patients with AHI were enrolled: 81 (52%) African-Americans, 63 (41%) white, non-Hispanics, 137 (88%) males, 108 (70%) men who have sex with men (MSM), and 18 (12%) females. The median age was 27 years (IQR 22-38). Most (n=138/155) reported symptoms with a median duration of 17.5 days. The median nadir CD4 count was 408 cells/mm(3) (IQR 289-563); the median observed peak HIV-1 level was 726,859 copies/ml (IQR 167,585-3,565,728). The emergency department was the most frequent site of initial presentation (n=55/152; 3 missing data). AHI diagnosis was made at time of first contact in 62/137 (45%; 18 missing data) patients. This prospectively enrolled cohort is the largest group of patients with AHI reported from the Southeastern United States. The demographics reflect the epidemic of this geographic area with a high proportion of African-Americans, including young black MSM. Highlighting the challenges of diagnosing AHI, less than half of the patients were diagnosed at the first healthcare visit. Women made up a small proportion despite increasing numbers in our clinics.