In well-established disciplines like history it is not common to find professionals who admit that they are driven by a “calling” or who say they have a “mission” to fulfill. In emerging disciplines, however, the situation is different: in order to gain recognition these new disciplines need highly driven practitioners, who’s calling enables them to overcome opposition or neglect from the side of the established disciplines. A clear example of such a practitioner with a mission in an emerging field of knowledge is the Dutch historian of science Eduard Jan Dijksterhuis (1892–1965). His career as a mathematics teacher, historical scholar, and public intellectual was marked by the desire to re-integrate science and mathematics in culture in general. Dijksterhuis regarded the history of science as a major instrument to bring about this ideal. His magnum opus, The Mechanization of the World Picture (first published in 1950 in Dutch; translated into English in 1961), was the culmination of a lifetime of writing in the service of a cultural vision that can still inspire our own generation.