ABSTRACT Electrocatalytic C─N coupling offers an efficient and sustainable pathway for glycine synthesis; however, its efficiency is limited by key intermediates conversion involving spin‐state reconfiguration. Herein, we develop a heterostructured catalyst that can induce a high density of Bi (OVs) sites with localized magnetic moments via oxygen‐vacancy formation at the Bi/Bi 2 O 3 interfaces. Within the eBi–Bi 2 O 3 catalyst, Bi sites serve as the primary adsorption sites for NO 3 − and the conversions of closed‐shell intermediates, while Bi (OVs) sites selectively facilitate the spin‐state reconfiguration of the adsorbed *NO to *NHO. This synergistic Bi/Bi (OVs) configuration promotes the subsequent formation of hydroxylamine as a crucial reaction intermediate and steers the reaction pathway toward favorable glycine synthesis. The eBi–Bi 2 O 3 catalyst exhibits an attractive Faradaic efficiency of 80.32% and yield rate of approximate 1000 µmol h −1 cm −2 for glycine synthesis, establishing one of the best overall performances reported to date. This work offers a pioneering strategy for developing spin catalysts applicable to electrochemical reactions involving complex multi‐step pathways.

Photodynamic Therapy This cover illustrates a lipid-hybridized nanoplatform (CSA-psICG/BdTT-BNBE) for cascade-activated photodynamic therapy. Guided by CSA–CD44 targeting, the system responds to dual-light irradiation (NIR and white light), triggering glutathione depletion and amplified ROS generation. This strategy enables spatiotemporally controlled activation and enhances therapeutic efficacy against tumors. More in the Research Article (e12546), Jeeyeon Lee, Jae-Young Lee, and co-workers.

Therapeutic Genome Editing In article number (e11362), Jounghyun Yoo, Seung Woo Cho, Jinmyoung Joo, and co-workers introduced a FAST-CRISPR (Fusogenic Association and Secured Transfection of CRISPR/Cas9) platform engineered for rapid cytosolic delivery of CRISPR/Cas9 ribonucleoproteins. By mediating direct membrane fusion to bypass endocytic pathways, it enables rapid cytosolic delivery and nuclear transport of ribonucleoproteins. This strategy successfully triggers targeted cancer cell apoptosis, establishing a promising non-viral genome editing tool.

Soft Electronics In article number (e11832), Jin Kon Kim, Chungryong Choi, and co-workers demonstrated a sustainable route from biomass-derived soft electronics to reusable raw materials through one-pot closed-loop chemical recycling. Devices made with bio-based components can be fully disassembled and recovered for re-fabrication without loss of performance, providing a scalable pathway toward zero e-waste soft electronic systems.

Lithium-Ion Batteries In the Research Article (e12020), Yuan Qiao and Ali Reza Kamali report a green and scalable strategy to develop a terephthalic acid-modified polyimide binder for silicon anodes. The binder enhances electrode integrity and kinetics, delivering improved capacity, cycling stability and full-cell performance for next-generation lithium-ion batteries.

Microbiome Sampling In article number e10289, Sarvesh Kumar Srivastava and co-workers show batch fabrication of monolithic devices with distinct activation and sampling chambers connected by a separator passage. The device design enables efficient low-volume luminal fluid capture with minimal cross-contamination, which could be scaled for large-animal and human studies for non-invasive, longitudinal gastrointestinal sampling.

Photonic Paper In article number 2509143, Yunpeng Wang, Wenbin Niu, Xi Yao, and co-workers report a nacre-inspired photonic paper fabricated via a roll-to-roll-assisted blade-coating process. The photonic paper exhibits a highly aligned "brick-and-mortar" architecture composed of α-zirconium phosphate nanoplates and a hydrogen-bonded polymer matrix, achieving an optimal balance between mechanical robustness, optical tunability, and scalability. This nacre-like design enables high-resolution and rewritable multicolour printing, as well as excellent flame retardancy, providing a promising platform for next-generation structural-colour paper.