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School-based social and emotional learning (SEL) programs have the potential to meaningfully foster healthy development. NaliniKIDS is a school-based program designed to focus on promoting SEL and school connectedness by bridging physical and mental health through exercises, a book series, and schoolwide activities. This mixed-method study explored the effects of NaliniKIDS on students’ mental health and school climate and the teachers’ perspectives regarding the implementation in a racially diverse, urban, Title I public elementary school. Quantitative data comprised of student (N = 253) and parent (N = 29) self-reports at pre- and post-test; qualitative data were collected via two focus groups with teachers (N = 10 participants). Survey results showed small increase in prosocial behavior among students after NaliniKIDS implementation. Focus groups highlighted the importance of training, protecting time and resources, and adapting the program to students’ background to maximize its implementation and relevance. NaliniKIDS may be a promising SEL program that facilitates the integration of physical and emotional health. The findings emphasize the health benefits of investments and policies focused on school-based programs that are integrated in the school. The successful implementation of SEL programs such as NaliniKIDS may significantly promote elementary student physical and mental health.

This chapter systematically analyzes hardware and software components independently, and explores their synthesis in modern engineering applications. It examines several foundational aspects, including purposes that drive development, pathways to realization, approaches to implementation, competitiveness in the market, customer satisfaction metrics, business viability assessments, and environmental responsibility considerations. The chapter also examines software engineering through its essential relationship with hardware, focusing on seven critical aspects. These include performance characteristics to show how software and hardware interactions affect system efficiency, architecture and design for creating robust integrated system structures, reliability and fault tolerance for ensuring system stability, security features, resource management for optimizing system resource allocation, testing and validation for verifying integrated system functionality, and development and maintenance for supporting the system throughout its lifecycle. It present examples of key technologies enabling current and future integrated systems, including sensor technology, networking and communication, software architecture, intelligent control systems, cross-cutting themes, and future development.

Engineering approaches are the sets of engineering processes that have been distilled from years of engineering practices throughout the profession. Prototyping is perhaps the most fundamental engineering process since the profession's inception. Engineering products typically progress through multiple stages: concept, design, prototype, validation, manufacturing, mass production, and service. Staging organizes these steps into distinct development phases. In engineering practice, the requirements are typically compiled into a document called design specifications, or simply specifications. Segmentation involves dividing system components into manageable units for design, testing, and final assembly. Documentation impacts multiple aspects of engineering with strict timing requirements. The interdisciplinary nature is fundamental to engineering success—each contributing discipline becomes essential to the final outcome. Contemporary engineering pursues cost-effectiveness due to its practical nature, distinguishing it from pure science. Reliability has been a long-standing value for engineering products, without which engineering may not have survived as a business.

The human peripheral nervous system (PNS) consists of many ganglia, including sympathetic ganglia (SG) and dorsal root ganglia (DRG), that house the cell bodies of many constituent neuron types and non-neuronal cells of the PNS. However, the molecular and cellular diversity of these human PNS cell types and their implications in human diseases remain elusive. By generating an integrated single-cell multi-omic atlas of human SG and DRG, we provide comprehensive transcriptional and epigenomic landscapes of various cell types in these peripheral ganglia. While the major cell types and their transcriptional and epigenomic features are similar between human SG and DRG, we identify key transcriptional and epigenomic differences between SG and DRG cell types, highlighting the distinct molecular mechanisms underlying their specific functions. Moreover, by mapping the expression and chromatin accessibility of disease-associated genes in human SG and DRG cell types, we identify cellular and molecular mechanisms that may underlie various peripheral neuropathies. This atlas serves as a valuable resource for understanding the intricate cell-type-specific molecules and interactions in the human PNS and their implications in human health and diseases.

The Single Sign-On based account linking process (SSOLinking in short) allows users to link their accounts at Service Provider (SP) websites to their Identity Providers (IdP) accounts. We focus on a serious (and overlooked) attack, namely an Account Hijack targeting the SSOLinking and relying on two CSRF vulnerabilities, one affecting the IdP and the other the SP. The former is an Authentication CSRF (also known as Login CSRF) and the latter is a CSRF on the button triggering the SSOLinking. We propose a security testing approach to help testers automatically detect such attacks. We implemented our testing technique as an extension (namely SSOLinking Checker) to the open-source penetration testing tool Micro-Id-Gym. To demonstrate the effectiveness of our approach and the pervasiveness of the SSOLinking Account Hijack, we conducted an experimental analysis against a selection of popular SPs that offer the SSOLinking with major IdPs. The results of our experiments are alarming: out of the 648 web sites we considered, 48 qualified for conducting our experiments and 21 of these suffered from SSOLinking vulnerability (i.e. 43.7%). Our findings (we responsibly disclosed to the affected vendors) include severe vulnerabilities among the web sites of Goodreads, Naver, Workable, etc.

The fulgorid name Alphina glauca (Metcalf) has been used erroneously since its inception to refer to a primarily southeastern U.S. species described originally as Calyptoproctus marmoratus Spinola. Additionally, at least three undescribed species from the Southwest have been incorrectly identified as A. glauca. The holotype of A. glauca has not been located. Since A. glauca is presently used to refer to multiple species, a neotype is designated which places A. glauca into synonymy with Calyptoproctus marmoratus. We establish a new genus, Scaralina, into which it is placed, giving the new combination Scaralina marmorata (Spinola), along with three southwestern, one Texan, and ten Mesoamerican taxa, named here as new species: S. aethrinsula, S. chapina, S. cristata, S. durango, S. gigantea, S. hawksi, S. metcalfi, S. monzoni, S. obfusca, S. obrienae, S. orientalis, S. rileyi, S. sullivani, and S. veracruzensis. Additionally, one new species of Scaralis in a new subgenus, Scaralis (Alphinoides) inbio, is described from Costa Rica and Guatemala. The limited information available suggests these insects feed on oaks (Quercus). The single defining putative synapomorphy for the subtribe Calyptoproctina is the enlarged apical plate on the female abdomen, which is absent in at least two members of Scaralina, and is also present in some genera that belong outside of Poiocerinae, so we reject the recognition of this subtribe. We consider that Scaralina is probably more closely related to the genus Scaralis Stål than to Alphina Stål. Based on morphology, some species originally described in Scaralis appear to be more closely related to one another than to the type species of the genus, and are here placed in a new subgenus, Alphinoides; Scaralis fluvialis Lallemand and Scaralis nigronotata Stål, plus three species originally described in Poiocera; Scaralis quadricolor (Walker) (the type species of Alphinoides), Scaralis semilimpida (Walker), and Scaralis spectabilis (Walker). Diagnoses are given for separation of the genera Scaralis and Scaralina, as well as the subgenus Alphinoides, plus descriptions of and keys to all species of Scaralina north of Panama, as well as keys to the genera corresponding to the former subtribe "Calyptoproctina" occurring north of Panama.

No cenário mercadológico atual, gerir a qualidade nas organizações agrega valor ao produto e causa satisfação ao cliente. Neste sentido, a pesquisa realizou um estudo de caso, por meio do qual analisou a eficácia das ferramentas da qualidade no mapeamento de problemas e no desenvolvimento de soluções em uma pizzaria localizada no centro do município de Tomé-Açú, região nordeste do Pará. Teve como objetivo identificar a razão dos atrasos nos pedidos de delivery, causa de reclamações dos clientes. Para o alcance dos objetivos, utilizou o ciclo PDCA como método para mapear problemas no setor produtivo da empresa até a entrega que é o consumidor final. Por meio das ferramentas 5W2H, Diagrama de Ishikawa e matriz GUT foram encontrados os gargalos que impedem um serviço de qualidade ao cliente, e também sugestões de correções e melhorias.

This study analyzed the epidemiological characterization of pathogens in acute diarrheal diseases in Incheon Metropolitan City from 2018 to 2021. The causative pathogens were detected in feces of patients (3,550 cases) who visited or were hospitalized for diarrhea at hospitals in Incheon. The highest bacterial detection rate was 28.2% at 6-9 years of age, followed by 24.1% at 10-19 years of age and 17.2% at 1-5 years of age. And the highest virus detection rate was 39.3% at 1-5 years of age, followed by 18.1% at under 1 year of age and 16.7% at 6-9 years of age. The detection rate of enteric pathogen exhibited typical seasonality; that of bacteria was high from July to August (summer), whereas that of viruses was high from November to April (early winter-spring). The most prevalent bacteria were Escherichia coli (205 cases), followed by Salmonella spp. (127 cases), Staphylococcus aureus (42 cases), Campylobacter jejuni (32 cases) and Bacillus cereus (27 cases). And the most prevalent viruses were Norovirus (313 cases), followed by Rotavirus (141 cases), Adenovirus (71 cases), Astrovirus (47 cases), Sapovirus (25 cases). Among the total of 3,550 cases, co-infection were observed in 114 cases. One hundred five cases had two pathogens, 8 cases had three pathogens and 1 cases had four pathogens. The most common types of co-infection were Escherichia coli -Norovirus and Norovirus -Rotavirus (13 cases respectively). Through this study, we confirmed the characteristics of acute diarrhea pathogens in Incheon Metropolitan City by age and season.

Alzheimer’s disease (AD) is the most common form of dementia, and causes a progressive decline in memory, language, executive and visuospatial function, personality, and behaviour. For many years, there have been only four approved medications to help improve cognition in patients with AD, but these only address the symptoms, and do not affect the course of the underlying disease. Here we discuss information presented at the 13th and 14th Clinical Trials on Alzheimer’s Disease conferences about the GREEN MEMORY trial (NCT04520412) of GV-971® (sodium oligomannate). This treatment, as well as the recently approved aducanumab, provides hope that new therapeutics with novel mechanisms of action may provide disease-modifying effects and help slow disease progression in people with AD.

Com a investigadora —tant a l'Institut de Recerca en Cultures Medievals de la Universitat de Barcelona com en el projecte Corpus Biblicum Catalanicum de l'Associació Bíblica de Catalunya—, Gemma Avenoza (1959–2021) centra una part dels seus interessos en la qüestió relativa a la presència i la circulació de la Bíblia en l'Europa medieval des d'unes perspectives —la de revisar els repertoris dels fons documentals i la d'inventariar els arxius pendents— desenvolupades a redós d'escriure i defensar la tesi de doctorat (1989). Es tracta d'unes opcions que, en la pràctica, la integren en la cadena que, pel que respecta a les anàlisis bíbliques, Samuel Berger (1843–1900) comença arran de finalitzar la primera etapa dels estudis teològics (1867). En certa manera, doncs, l'oportunitat d'homenatjar Avenoza brinda la circumstància de reivindicar Berger. Per assolir-ho, aquest article en recupera —i en rellegeix en clau filològica— la contribució «Nouvelles recherches sur les bibles provençales et catalanes » (1890). No endebades, inaugura la recerca acadèmica entorn de les traduccions bíbliques catalanes medievals a partir dels testimonis manuscrits. A més, articula la proposta primicera adreçada a donar-ne raó amb una voluntat global. I, principalment, orienta, amb les seves afirmacions conclusòries, totes les percaces posteriors sobre aquestes traduccions bíbliques, entre les quals destaquen les de Josep Perarnau (1978-1983), Josep Izquierdo (1997), Armand Puig (1997-2001) i Pere Casanellas / Armand Puig (2004-2021). Comptat i debatut, heus aquí l'estela també prosseguida per Avenoza.