MSR8 Revolutionizing Drug Discovery and Preclinical Research Via Artificial Intelligence: A Targeted Literature Review

The article is devoted to the study of the application of artificial intelligence technologies in law enforcement activities in Ukraine and the world. The purpose of the article is to analyze the international and domestic experience of using digital technologies in law enforcement activities, to identify the shortcomings of the legal regulation of the use of artificial intelligence in this area, to provide proposals for its improvement in Ukraine. It was found that one of the countries that is actively expanding the use of artificial intelligence and successfully introducing relevant technologies into public administration is China. The artificial intelligence system which is used in China called «Zero Trust». The purpose of using this system is to prevent the commission of corruption offenses. It is emphasized, that the disadvantage of the «Zero Trust» system is that artificial intelligence, identifying the cause of corruption, does not indicate the algorithms and principles of this process. At the same time, the experience of using artificial intelligence in the field of preventing and combating corruption in Ukraine is considered when carrying out automated verification of persons declarations of authorized to perform state and local government functions. Ways of improving legal regulation when conducting financial control of declarations using artificial intelligence technologies are proposed. It has been found that artificial intelligence is widely used in the USA to predict the prevalence and state of crime. It was emphasized that Ukraine also has experience in the application of artificial intelligence technologies in law enforcement activities. Artificial intelligence is used in the development and implementation of departmental specialized intelligent software, the implementation of operative and investigative actions (for the recognition of video objects observation by comparing images in social networks, etc). It was concluded that artificial intelligence and digital technologies help to quickly process large volumes of information in the investigation and prevention of criminal activity. Modern developments in the field of artificial intelligence and advanced digital technologies, which are implemented in foreign countries to prevent and fight crime, are of great importance for the improvement of legal regulation in this field in Ukraine.

Drug discovery and development (DDD) is a highly complex process that necessitates precise monitoring and extensive data analysis at each stage. Furthermore, the DDD process is both timeconsuming and costly. To tackle these concerns, artificial intelligence (AI) technology can be used, which facilitates rapid and precise analysis of extensive datasets within a limited timeframe. The pathophysiology of cancer disease is complicated and requires extensive research for novel drug discovery and development. The first stage in the process of drug discovery and development involves identifying targets. Cell structure and molecular functioning are complex due to the vast number of molecules that function constantly, performing various roles. Furthermore, scientists are continually discovering novel cellular mechanisms and molecules, expanding the range of potential targets. Accurately identifying the correct target is a crucial step in the preparation of a treatment strategy. Various forms of AI, such as machine learning, neural-based learning, deep learning, and network-based learning, are currently being utilised in applications, online services, and databases. These technologies facilitate the identification and validation of targets, ultimately contributing to the success of projects. This review focuses on the different types and subcategories of AI databases utilised in the field of drug discovery and target identification for cancer.

In addition to creativity, modern landscape design also needs some auxiliary tools to predict the design effect, so as to ensure the design effect before the completion of the landscape. With the development of computer network and electronic information technology, human society has entered the information age, and artificial intelligence technology has been applied to all walks of life. With the continuous development of artificial intelligence, artificial intelligence has existed in all aspects of our lives and has a great impact on our lives. At the same time, through the achievements in recent years, artificial intelligence gradually affects other fields such as design. Therefore, combined with the current situation of landscape design auxiliary system in China, this paper introduces artificial intelligence and information technology into it, and makes the landscape design auxiliary system get further development with the help of artificial intelligence and information technology. This paper first introduces artificial intelligence, analyzes the advantages and development trend of automatic informatization of landscape design auxiliary system, and finally discusses the application of artificial intelligence technology in landscape design auxiliary system.

AI Applications in Health Sector: Use of Artificial Intelligence in Covid-19 Crisis and Impacts of Medical Robots on Global Economy

The acceptance of technology at the higher educational level has been a significant discussion, with little attention on the gender dynamics on the acceptance of artificial intelligence (AI ) tools by senior lecturers. This study delved into a detailed analysis of the gender dynamics in the discussion of technology acceptance mainly AI tools, in foreign language (FL) education. Quantitative study approach was adopted in the process, and survey design was implemented. Data was collected using structured digital questionnaire, based on the Unified Theory of Acceptance and Use of Technology (UTAUT) model. A total of ninety-five (95) male senior lecturers and one hundred and three (103) female senior lecturers participated in the study. Analysis was conducted using relevant statistical measures. The results showed disparities in the attitudes and views of senior lecturers towards artificial intelligence (AI) technologies in the context of FL education, greatly influenced by gender. In relation to usage, male senior lecturers have higher positive reactions (61.06%) in comparison to their female counterparts (46.6%). However, in relation to the assumption that AI technologies improve the performance of learners, 69% of male senior lecturers agree with this notion, but a substantially greater percentage of 72.81% of female senior lecturers hold the same perspective. Moreover, there exists a little disparity in the level of proficiency in using AI technologies across genders. Specifically, 56.84% of male senior lecturers see it as uncomplicated, while 61.16% of their female counterparts share the same sentiment. The gender discrepancy that is most notable pertains to the perceived level of ease in using artificial intelligence (AI) technologies during foreign language (FL) lessons. The data reveals that a majority of male senior lecturers, calculated as 69.48%, see the use of these tools very easy. In contrast, a much higher proportion of female senior lecturers, 86.41%, share the same perception. This discrepancy highlights a notable disparity in confidence levels between the two genders. These results together emphasise the changing gender dynamics in the acceptance of technology, interrogating conventional assumptions and underscoring the need for customised support systems to guarantee fair and efficient integration of artificial intelligence (AI) technologies in foreign language instruction among senior lecturers.

Drug discovery research is a rational science aimed to identify new drugs to alleviate symptoms of numerous health problems. It takes around 10–15 years to develop a new drug with concerted efforts of multidisciplinary scientists. The cost of bringing a new drug to the market is approximately $2.6 billion. Only 10% of the promising drug candidates make it to the clinic. Rational drug design techniques have become very common in drug discovery research and expedite initial stage of screening. Artificial intelligence (AI) can exploit large chemical database from combinatorial chemistry and high-throughput screening to extract significant chemical and biological information to accelerate development of drugs and simultaneously cut down expenses of discovering new drugs. AI can assist new drug discovery in numerous ways like predicting targets for a disease and their three-dimensional structures for structure-based drug design, coming up with entirely novel chemical structure and its route of synthesis, improving reproducibility of results, accelerating repurposing of drugs for new therapeutic applications, prediction of toxicities, and other desired molecular properties in designed molecules, prioritization of potential drug candidate, and identifying privileged scaffolds. Several organizations like Merck, Schrodinger, Relay Therapeutic, and NVIDIA are investing in AI-driven drug discovery and development. This chapter will discuss in detail the vital role of AI in advancing various stages of drug discovery and development process and future directions.

In an era where artificial intelligence (AI) technology is increasingly penetrating various aspects of life, including education, it is important to understand its impact on students' social relationships. These changes raise questions about how interactions between students and teachers are affected by AI Technology. This research aims to investigate the impact or artificial intelligence on students' social relationships in an educational environment. The focus is on understanding changes in interactions between students, student-teacher interaction, as well as broader implications for social dynamics inside the classroom and outside the classroom. The research method used is a literature review which uses data collections sources that are relevant to this research, which can be in books, megazines and other print media, or can be obtained from photos and videos. The research results show that artificial intelligence technology has a complex impact on students' social relationships. Although it can improve efficiency and learning outcomes, AI technology can also reduce social inequality, and create excessive dependence on technology. Educators and policymakers need to carefully consider the use of AI technology in education to ensure that positive impacts are maximized, while negative impacts are minimized.

Artificial intelligence (AI) technology, as one of the most sophisticated science and technology in today's world, is increasingly being used to production and life, particularly in the manufacturing business. it demonstrates how artificial intelligence technology is used in mechanical manufacturing, namely in defect detection, quality inspection, enhancing workplace safety, and other areas. Artificial intelligence technology is becoming increasingly important in people's lives as it becomes more widely used in people's daily lives, such as the widespread use of smart dishwashers and smart sweepers, which are the products of the fusion of artificial intelligence and the mechanical manufacturing industry. Indeed, artificial intelligence technology has been widely utilized in the mechanical manufacturing business, which not only ensures production precision, but also enhances job productivity and workplace safety. The rise of artificial intelligence has caused significant changes in the manufacturing industry as a whole. Without exception, the manufacturing industry must rely on AI technology to accomplish automation and intelligent development, as well as to improve productivity. Using artificial intelligence to categorize mechanical components, we may propose parts from a based solely on an image or CAD model. To find a necessary component in a machines we must currently browse through a catalogue and be able to discern which part you want based on the available possibilities and your understanding of the catalogue. There are serial numbers to memorize since a single digit or character change might indicate a different sort of part. The algorithm will choose which sections are the best and will significantly facilitate our search.

PurposeThe introduction of artificial intelligence (AI) technology has had a substantial influence on the retail industry. However, AI adoption entails considerable responsibilities and risks for senior managers. In this study, the authors developed an evaluation and selection mechanism for successful AI technology adoption in the retail industry. The multifaceted measurement and identification of critical factors (CFs) can enable retailers to adopt AI technology effectively and maintain a sustainable competitive advantage.Design/methodology/approachThe evaluation and adoption of organisational AI technology involve multifaceted decision-making for management. Therefore, the authors used the analytic network process to develop an AI evaluation framework for calculating the weight and importance of each consideration. An expert questionnaire survey was distributed to senior retail managers and 17 valid responses were obtained. Finally, the Vlse Kriterijumska Optimizacija Kompromisno Resenje (VIKOR) method was used to identify CFs for AI adoption.FindingsThe results revealed five CFs for AI adoption in the retail industry. The findings indicated that after AI adoption, top retail management is most concerned with factors pertaining to business performance and minor concerned about the internal system's functional efficiency. Retailers pay more attention to technology and organisation context, which are matters under the retailers' control, than to external uncontrollable environmental factors.Originality/valueThe authors developed an evaluation framework and identified CFs for AI technology adoption in the retail industry. In terms of practical application, the results of this study can help AI service providers understand the CFs of retailers when adopting AI. Moreover, retailers can use the proposed multifaceted evaluation framework to guide their adoption of AI technology.

Scientific studies related to information on possible treatments and vaccines have been growing with the development of the COVID-19 pandemic. The research databases are publicly available, which provides a solid resource in supporting the global research community. However, challenges remain in terms of searching the insightful information quickly for the purpose of finding the right treatments and vaccines in the current situation. Artificial intelligence technologies can help to build tools in order to search, rank, extract, and aggregate useful results from enormous databases. This chapter presents a systematic review for investigating current research in drug discovery and vaccine development for COVID-19 throughout protein structural basis analysis and visualization, machine learning- and deep learning-based models, and a big data-driven approach. The survey study indicates that applied big data and AI can generate new insights in support of the ongoing fight against COVID-19 in terms of developing new drugs and vaccines efficiently.

Objectives: The objective of this scientific paper is to shed light on the challenges facing the legislative industry in the field of artificial intelligence (AI) technologies. Specifically, it aims to anticipate and predict the difficulties related to creating an independent legal personality for AI tools, enabling them to assume rights and obligations, as well as establishing criminal responsibility and punishment in cases where AI technologies commit crimes punishable by law. Methods: To achieve the stated objectives, this paper employs a theoretical and analytical approach. It involves a comprehensive review and analysis of existing literature, legal frameworks, and case studies related to the legal implications of AI technologies. Additionally, hypothetical scenarios and potential challenges are discussed to illustrate the complexities involved in creating legal frameworks that address the unique nature of AI tools and their impact on society. Results: The analysis reveals several key challenges facing the legislative industry in the field of AI technologies. These challenges include the conceptualization of an independent legal personality for AI tools, determining the rights and obligations associated with such personality, and establishing mechanisms for holding AI technologies accountable for their actions. Furthermore, the paper explores the difficulties in imposing criminal responsibility and punishment on AI technologies in cases where they commit crimes. Conclusion: In conclusion, this scientific paper highlights the complexities and challenges associated with creating legal frameworks for AI technologies. By anticipating and predicting these challenges, it provides valuable insights for legislators, policymakers, and legal professionals involved in shaping the regulatory landscape for AI. Moving forward, it is essential to address these challenges proactively and develop legal frameworks that strike a balance between promoting innovation and safeguarding societal interests in the era of artificial intelligence.

The convergence of blockchain, artificial intelligence (AI), and cloud computing is catalyzing a paradigm shift in developing secure, intelligent, and scalable digital infrastructures. This triad of technologies is increasingly utilized to improve performance, transparency, and trust in engineering-driven and socio-technical environments. This study systematically reviews the evolution, integration strategies, and applications of blockchain, AI, and cloud computing in digital ecosystems. The analysis is based on 108 peer-reviewed studies spanning the years 2012 to 2025. A comprehensive literature analysis was conducted to identify trends, synergies, and sector-specific implementations of these systems. The review explores how their integration supports real-world engineering and operational use cases. Blockchain contributes to decentralized architectures, secure data exchange, and identity verification. AI supports adaptive behavior, autonomous decision-making, and predictive analytics. Cloud computing offers the scalable infrastructure necessary for deployment. Key challenges addressed include interoperability, latency, security trade-offs, and resource allocation. Use cases in digital finance, supply chain management, and industrial automation demonstrate the effectiveness of this integration in building resilient, ethically aligned, and high-performance infrastructures. The findings offer valuable insights and technical considerations for engineers and architects seeking to design next-generation cyber-physical systems that are secure, intelligent, and socially responsive. Clinical Trial Number Not applicable. This article accentuates the extensive use of blockchain, cloud computing, and AI principles, emphasizing their crucial significance in the contemporary digital environment and paths in which blockchain technology may be employed to automate financial transactions, enhance the security of personal data and records, facilitate cross-border transactions, verify identities, execute smart contracts, utilize cryptocurrencies, and manage supply chains. This research systematically assesses the development and practical application of blockchain, cloud computing, and artificial intelligence technologies over the past decade. This study primarily focuses on monitoring the progress, practical applications, and benefits of blockchain technology in the context of financial transactions. This article probes the symbiotic relationship between artificial intelligence, cloud and blockchain technology, analyzing the evolution and fundamental concepts of their integration from 2012 to 2025. This paper also presents a detailed analysis of 108 research works acquitted over the past decade. The study provides a comprehensive examination of the current state and fundamental principles related to the integration of artificial intelligence, cloud, and blockchain technology. This paper offers a comprehensive analysis of the major obstacles confronted by blockchain technology, examining its wide-ranging applications over several industries and its socko role in transaction systems and the domain of cryptocurrencies.

Everything related to Artificial Intelligence (AI) technology has a crucial role to play in helping to improve efficiency, lowering expenses, and optimizing decision-making across numerous industries, including accounting, where Generation Z accountants, particularly in Batam, must continuously develop their skills and readiness to leverage AI despite challenges related to data privacy and security. This research seeks to evaluate the readiness of a Generation Z accountant to embrace artificial intelligence (AI) technology by applying the Technology Acceptance Model (TAM). In the context of the fourth industrial revolution, AI adoption is crucial for improving efficiency and effectiveness in accounting practices. The study employs a quantitative approach with purposive sampling, involving 220 Generation Z accountant participants from Batam City. The analysis, conducted using the PLS-PM method in R programming and data processing with Google Colab statistics, reveals that the Technology Readiness (TR) variable significantly influences the interest of Generation Z accountants in adopting AI technology. While the perceived ease of use (PEOU) variable showed no significant effect, perceived usefulness (PU) emerged as the dominant factor in technology adoption. The R-Squared value of 0.920 indicates that 92% of the variables influencing AI technology adoption are explained by TR and PU. This study highlights the importance of technology readiness in helping Generation Z accountants adapt to technological advancements and offers recommendations for enhancing education, training, and technology development within the accounting profession.

PurposeThis article aims to elaborate on the current relevant policies, research literature and technical applications of administrative intelligent decision-making in major countries in the world, to summarize the current focus areas of international competition in administrative intelligent decision-making and to provide references and insights for other countries.Design/methodology/approachThe knowledge graph tool CiteSpace was used to conduct a quantitative analysis of the field of administrative intelligent decision-making, using the two dimensions of research literature and technology patents to analyze the basic status and evolution process of artificial intelligence applied to administrative decision-making.FindingsOver the past 30 years, theoretical research on administrative intelligent decision-making has primarily centered on countries like the United States of America, China and Japan. The main themes include leveraging artificial intelligence (AI) technology to enable digital government transformation, enhance administrative efficiency and promote public value through service-oriented initiatives. Countries like South Korea, China and the United States of America have demonstrated significant advantages in technology development and patent applications, focusing on e-government systems, intelligent government auditing, addressing policy mismatches between supply and demand and integrating online and offline administrative services. The international competitive landscape in this field is shaped by three key factors: foundational theories, technological advancements and practical scenario applications.Originality/valueDespite the rapid advancements in AI technology and the acceleration of enterprise digital transformation, discussions on the intelligent transformation of administrative decision-making leveraging next-generation information technology remain limited. This study summarizes the development trajectory of administrative intelligent decision-making in major countries worldwide, analyzes the international competitive landscape of its theoretical and application research and highlights key focus areas. These findings offer valuable insights for advancing the construction of administrative intelligent decision-making systems in other nations.

Art education has undergone significant transformation in the era of digitalization. With the advancement of Artificial Intelligence (AI) technology, there is tremendous potential to enhance the art learning experience. This research aims to elucidate how AI technology can be effectively utilized to improve art education in the context of digitalization. The study aims to introduce AI technology and explore its potential applications in enhancing the art learning experience. In the context of art learning experience, AI technology can provide broader access to digital art collections, online galleries, and virtual museums. Students can explore various artworks and cultures through digital platforms, thereby enriching their understanding and appreciation of art. The research findings reveal that AI technology can offer personalized guidance to students in developing their artistic skills. Intelligent AI systems can analyze students' artworks, provide tailored suggestions, and assist in enhancing their technical and creative abilities. In conclusion, the integration of AI technology in art education holds immense potential to elevate students' learning experiences. By expanding access, providing personalized guidance, and creating interactive experiences, AI technology enriches art learning in the era of digitalization. This is expected to provide greater insights and understanding of how AI technology can be harnessed to enhance the art learning experience in the context of digitalization. By optimizing the potential of AI, art education can become more inclusive, personalized, and engaging.