PSYCHOLOGIES OF SMALL DIFFERENCES.

Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets

Efforts to Describe Mental Illnesses Continue to Make Progress

Fascinating Sessions in Exciting City Promise Not-to-Be-Missed Meeting

Journal of Comparative NeurologyVolume 64, Issue 2 p. 313-324 Article Lamination of the medial lemniscus in Macacus rhesus A. Ferraro, A. Ferraro Department of Neuropathology, New York State Psychiatric Institute and Hospital, New YorkSearch for more papers by this authorS. E. Barrera, S. E. Barrera Department of Neuropathology, New York State Psychiatric Institute and Hospital, New YorkSearch for more papers by this author A. Ferraro, A. Ferraro Department of Neuropathology, New York State Psychiatric Institute and Hospital, New YorkSearch for more papers by this authorS. E. Barrera, S. E. Barrera Department of Neuropathology, New York State Psychiatric Institute and Hospital, New YorkSearch for more papers by this author First published: August 1936 https://doi.org/10.1002/cne.900640208Citations: 11AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume64, Issue2August 1936Pages 313-324 RelatedInformation

CancerVolume 15, Issue 5 p. 1009-1018 ArticleFree Access Comparative data on cancer in aging twins Lissy F. Jarvik M.D., PH.D., Lissy F. Jarvik M.D., PH.D. Department of Medical Genetics, New York State Psychiatric Institute, 722 W. 168th St., New York 32, N.YSearch for more papers by this authorArthur Falek PH.D., Arthur Falek PH.D. Department of Medical Genetics, New York State Psychiatric Institute, 722 W. 168th St., New York 32, N.YSearch for more papers by this author Lissy F. Jarvik M.D., PH.D., Lissy F. Jarvik M.D., PH.D. Department of Medical Genetics, New York State Psychiatric Institute, 722 W. 168th St., New York 32, N.YSearch for more papers by this authorArthur Falek PH.D., Arthur Falek PH.D. Department of Medical Genetics, New York State Psychiatric Institute, 722 W. 168th St., New York 32, N.YSearch for more papers by this author First published: September/October 1962 https://doi.org/10.1002/1097-0142(196209/10)15:5<1009::AID-CNCR2820150518>3.0.CO;2-9Citations: 19AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume15, Issue5September/October 1962Pages 1009-1018 ReferencesRelatedInformation

Back to table of contents Previous article Next article Clinical and Research NewsFull AccessTrial of Interpersonal Therapy May Open New Door to Treat PTSDAaron LevinAaron LevinSearch for more papers by this authorPublished Online:16 Apr 2015https://doi.org/10.1176/appi.pn.2015.4b1AbstractInterpersonal therapy gets a closer comparison to other treatments for posttraumatic stress disorder and shows encouraging results without the added stress of exposure therapy.A randomized trial of posttraumatic stress disorder (PTSD) treatments has found that interpersonal therapy (IPT) was “roughly equipotent” with exposure therapy, the current gold standard for treating the disorder.Results of the new study suggest a useful alternative, assuming that it is replicated in larger and more diverse cohorts.In 2008, the Institute of Medicine said exposure-based therapies for PTSD were the only ones for which there was good evidence of efficacy.“These findings contradict the widespread clinical belief in PTSD therapeutics that patients require cognitive-behavioral therapy or exposure to trauma reminders,” wrote John Markowitz, M.D., a research psychiatrist at the New York State Psychiatric Institute and a professor of clinical psychiatry at Columbia University College of Physicians and Surgeons, and colleagues in the February 13 AJP in Advance. “We found what many have suspected: exposure therapy is valuable, but not a sine qua non.”The researchers randomly assigned 38 participants to prolonged exposure therapy, 40 to interpersonal psychotherapy, and 32 to relaxation therapy. About half of each group had comorbid depressive disorder. The study sought to test whether IPT was “no more than minimally inferior to prolonged exposure.” IPT produced improvements on the Clinician-Administered PTSD Scale (CAPS) that were only 5.5 points worse than exposure therapy, less than the 12.5-point threshold set in advance for inferiority. Response rates were also clinically better, although statistically nonsignificant. “The results show that both exposure therapy and IPT are effective in treating PTSD to a similar degree, one that seems better than the control condition,” said Daniel Pine, M.D., chief of the Section on Development and Affective Neuroscience in the National Institute of Mental Health (NIMH) Intramural Research Program, in an interview with Psychiatric News.“This is a particularly important study because it includes the gold-standard psychotherapy, exposure, plus a suitable control—relaxation therapy—and a therapy we usually think of as beneficial in depression, interpersonal therapy,” added Pine, who was not involved with Markowitz’s research.IPT was developed to treat depression, possibly explaining the lower dropout rate among depressed patients treated with IPT compared with those receiving exposure therapy. Its mechanism of action likely differs as well.“IPT may work through alternative attachment mechanisms involving emotional understanding, social support, and learning to cope with current life rather than confronting past traumas,” suggested Markowitz and colleagues. “Yet, in order to remit from PTSD, patients must eventually face their fears. As previously reported, patients who improved in IPT seemed to gain confidence in daily social interactions, gathered social support, and then spontaneously—without therapist encouragement—exposed themselves to trauma reminders.”Thus, Pine said, the study expands the range of treatments that might be useful in treating PTSD.The study was funded by NIMH. ■An abstract of “Is Exposure Necessary? A Randomized Clinical Trial of Interpersonal Psychotherapy for PTSD” can be accessed here. ISSUES NewArchived

Experiences With a Novel Policy for Managing Conflicts of Interest of Guideline Developers

Journal of School HealthVolume 38, Issue 1 p. 18-26 THE BALANCE* Gert Heilbrunn M.D., Gert Heilbrunn M.D. Clinical Professor of Psychiatry, University of Washington, Seattle, Washington.Search for more papers by this author Gert Heilbrunn M.D., Gert Heilbrunn M.D. Clinical Professor of Psychiatry, University of Washington, Seattle, Washington.Search for more papers by this author First published: January 1968 https://doi.org/10.1111/j.1746-1561.1968.tb04936.x * Read at the Eighth Annual School Nurse Educational Conference, Tacoma, Washington, October 20, 1967. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume38, Issue1January 1968Pages 18-26 RelatedInformation

Luft and 0livecrona.s~ 4 Pearson et aL,@ and Ray and Pearson.

High levels of high sensitive C-reactive protein (hs-CRP), homocysteine (Hcy) and oxidative stress are known to be associated with premature vascular disease in type 2 diabetes mellitus (DM). The aim of this study was to estimate homocysteine levels and oxidant-antioxidant status and to determine the relationship between them in type 2 diabetic patients with and without microalbuminuria. The study population consisted of 75 subjects [age and sex-matched] divided into three groups. Fasting blood samples were obtained from 50 diabetic patients (25 with and 25 without microalbuminuria) and 25 healthy subjects. The level of blood glucose, HbA1C, urea, creatnine and serum lipids were significantly higher in the patients with microalbuminuria compared with patients without microalbuminuria and control subjects, comparatively higher level in patients with microalbuminuria. On the other hand HDL-C was found to be significantly lower in patients with microalbuminuria. The level of hs-CRP and Hcy levels were found to be significantly higher in patients with microalbuminuria compared with patients without microalbuminuria and healthy controls. The level of plasma thiobarbituric acid reactive substances (TBARS) was markedly increased and the level of enzymic and non-enzymic antioxidant was significantly decreased in the patients with microalbuminuria compared with patients without microalbuminuria and control subjects. The present study highlights the occurrence of lipid peroxidation and possible breakdown of antioxidant status in patients with microalbuminuria. Decreased antioxidant levels, increased lipid peroxidation and increased hs-CRP and Hcy levels were observed in patients with microalbuminuria.

Journal Article Experimental Allergic Encephalomyelitis Induced by Brain Fractions Containing Mitochondria Get access L. Roizin, M.D., L. Roizin, M.D. †Dept. of Neuropathology, New York State Psychiatric Institute and Dept. of Pathology, College of Physicians and Surgeons, Columbia University, New York. Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Berger Wechsler, Ph.D. M. Berger Wechsler, Ph.D. ‡Dept. of Experimental Psychiatry, New York State Psychiatric Institute and Dept. of Biochemistry, College of Physicians and Surgeons, Columbia University, New York. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Neuropathology & Experimental Neurology, Volume 18, Issue 4, October 1959, Pages 636–644, https://doi.org/10.1097/00005072-195910000-00016 Published: 01 October 1959

CancerVolume 4, Issue 4 p. 726-736 ArticleFree Access Glomus tumors of the stomach S. Kay M.D., S. Kay M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorW. P. Callahan Jr. M.D., W. P. Callahan Jr. M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorM. R. Murray Ph.D., M. R. Murray Ph.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorH. T. Randall M.D., H. T. Randall M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorA. P. Stout M.D., A. P. Stout M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this author S. Kay M.D., S. Kay M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorW. P. Callahan Jr. M.D., W. P. Callahan Jr. M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorM. R. Murray Ph.D., M. R. Murray Ph.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorH. T. Randall M.D., H. T. Randall M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this authorA. P. Stout M.D., A. P. Stout M.D. Surgical Pathology Laboratory, College of Physicians and Surgeons, Columbia University, and the Department of Surgery, Presbyterian Hospital, New York, New YorkSearch for more papers by this author First published: July 1951 https://doi.org/10.1002/1097-0142(195107)4:4<726::AID-CNCR2820040410>3.0.CO;2-ZCitations: 48AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume4, Issue4July 1951Pages 726-736 ReferencesRelatedInformation

Annals of the New York Academy of SciencesVolume 118, Issue 10 p. 471-485 PHONOCINEFLUOROCARDIOGRAPHY AND INDIRECT LEFT A TRIAL PULSES IN ASSESSMENT OF MITRAL VALVE DISEASE* W. M. Rogers, W. M. Rogers Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorK. Ellis, K. Ellis Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorJ. S. Harrison, J. S. Harrison Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorJ. D. Baker, J. D. Baker Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorM. Pinchot, M. Pinchot Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this author W. M. Rogers, W. M. Rogers Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorK. Ellis, K. Ellis Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorJ. S. Harrison, J. S. Harrison Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorJ. D. Baker, J. D. Baker Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this authorM. Pinchot, M. Pinchot Departments of Anatomy and Radiology, Columbia University and the Radiological Service. Presbyterian Hospital, New York, N.Y.Search for more papers by this author First published: January 1965 https://doi.org/10.1111/j.1749-6632.1965.tb33969.xCitations: 1 * Supported by a grant from the Lillie Babbitt Hyde Foundation. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume118, Issue10Mitral Valve DiseaseJanuary 1965Pages 471-485 RelatedInformation

Recent trends in adolescent sexual behavior offer mixed messages. It is very encouraging that teenagers’ overall rates of sexual activity, pregnancy and childbearing are decreasing, and that their rates of contraceptive and condom use are increasing. 1 However, the proportion of young people who have had sex at an early age has increased. 2 Moreover, while adolescent females’ contraceptive use at first sex is rising, their use at most recent sex is falling. 3 There is general consensus that the proportion of teenagers who engage in behaviors that put them at risk of pregnancy and of HIV and other sexually transmitted infections (STIs) remains too high. Each year, approximately one million young women aged 15–19—or one-fifth of all sexually active females in this age-group—become pregnant; the vast majority of these pregnancies are unplanned. 4 In the United States, the risk of acquiring an STI is higher among teenagers than among adults. 5 Moreover, rates of unprotected sexual activity, STIs, pregnancy and childbearing continue to be substantially higher among U.S. adolescents than among young people in comparable industrialized countries. 6 Research has also begun to highlight an alarmingly high rate of involuntary sex among young people. In the 1995 National Survey of Family Growth, 13% of 15–19-year-old females reported that they had been forced to have sex. 7 When asked about their first sexual experience, 22% of 15–44-year-old women for whom it occurred before age 15 reported that the act was involuntary, as did 16% of those who first had sex before age 16. Involuntary sexual activity is typically unprotected and thus puts its victims at very high risk of pregnancy and STIs. Finally, recent research and clinical observations suggest that a substantial proportion of teenagers, including those who report having never had vaginal sex, are engaging in oral sex. 8 This trend has negative implications for teenagers’ sexual health because many seem unaware that STIs can be acquired through unprotected oral sex.

Philosophical PerspectivesEarly View ORIGINAL ARTICLE Modal Pluralism and Higher-Order Logic Justin Clarke-Doane, Corresponding Author Justin Clarke-Doane [email protected] Columbia University & Institute for Advanced Study, Princeton Correspondence Justin Clarke-Doane, Columbia University & Institute for Advanced Study, Princeton. Email: [email protected] William McCarthy, Columbia University. Email: [email protected]Search for more papers by this authorWilliam McCarthy, Corresponding Author William McCarthy [email protected] Columbia University Correspondence Justin Clarke-Doane, Columbia University & Institute for Advanced Study, Princeton. Email: [email protected] William McCarthy, Columbia University. Email: [email protected]Search for more papers by this author Justin Clarke-Doane, Corresponding Author Justin Clarke-Doane [email protected] Columbia University & Institute for Advanced Study, Princeton Correspondence Justin Clarke-Doane, Columbia University & Institute for Advanced Study, Princeton. Email: [email protected] William McCarthy, Columbia University. Email: [email protected]Search for more papers by this authorWilliam McCarthy, Corresponding Author William McCarthy [email protected] Columbia University Correspondence Justin Clarke-Doane, Columbia University & Institute for Advanced Study, Princeton. Email: [email protected] William McCarthy, Columbia University. Email: [email protected]Search for more papers by this author First published: 02 March 2023 https://doi.org/10.1111/phpe.12165Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Early ViewOnline Version of Record before inclusion in an issue RelatedInformation